more than just a brc

... impaired, hidden genetic variation is revealed, resulting in altered genetic signal inputs (black peaks) that are abnormally outputted These altered outputs may lead to an abnormal phenotypic variation ... cycle, transposons are both a source of piRNAs and a target of piRNA-mediated silencing However, classification of piRNAs according to their origins indicated that piRNAs derived from a particular ... AGO3, Aubergine, and Piwi, all of which exhibit the small RNA-guided ribonuclease (‘Slicer’) activity Deep sequencing and bioinformatic analyses of Drosophila piRNAs suggest a model for piRNA...

Ngày tải lên: 09/08/2014, 20:21

... calibration for whole blood and plasma And just what is the standard reference method for glucose [10], and should there not be a reference method for each sample type - whole blood, plasma and ... intensive care unit patients Critically ill patients may have very low hematocrits, high or low arterial of venous oxygen tensions and may present extreme acid-base abnormalities, all of which have ... accuracy have to be determined using standardized protocols and care has to be taken to choose the suitable reference method [10], which may not be the one available in the central laboratory where...

Ngày tải lên: 13/08/2014, 03:20

... Szekanecz Z, Koch AE: Macrophages and their products in rheumatoid arthritis Curr Opin Rheumatol 2007, 19:289-295 Martinez FO, Sica A, Mantovani A, Locati M: Macrophage activation and polarization ... patients who failed all the conventional Available online http://arthritis-research.com/content/11/4/237 treatments and, hence, had more active RA were assessed, RA patients with a broader range ... many other immune cells, the role of macrophages cannot be simply associated with inflammation, and a distinct subset of macrophages can also act as suppressive cells via immunomodulatory factors,...

Ngày tải lên: 09/08/2014, 14:22

... slides used to measure TC, HDL, and TGs, whereas a dual chamber package was used to assess LDL, apolipoprotein (Apo) A and ApoB Insulin resistance was evaluated from fasting glucose and insulin using ... patients Ann Rheum Dis 1990, 49:363-369 Han C, Robinson DWJ, Hackett MV, Paramore LC, Fraeman KH, Bala MV: Cardiovascuar disease and risk factors in patients with rheumatoid arthritis, psoriatic ... rheumatoid arthritis patients as in non-rheumatoid arthritis patients? Ann Rheum Dis 2008, 67:64-69 11 Gonzalez-Gay MA, Gonzalez-Juanatey C, Lopez-Diaz MJ, Pineiro A, Garcia-Porrua C, Miranda-Filloy JA,...

Ngày tải lên: 09/08/2014, 14:22

... significance In addition to using archival data as a primary source of data, this study also uses multiple additional sources of data such as national and international statistics, involving information ... the Marina Barrage Area 122 Figure 5.3: Marina Barrage: Sustainable Singapore Gallery - 124 List of Abbreviations ABC Waters Program - Active, Beautiful and Clean ... Singapore’s water management system over the past four to five decades was available for analysis A systematic and organized manner of going through, sorting out and codification of the data was...

Ngày tải lên: 13/10/2015, 16:50

... Quezia Leandro Moura and Maria Lucia Jardim Macambira Chapter 11 Plant Productivity is Temporally Enhanced by Soil Fauna Depending on the Life Stage and Abundance of Animals 253 Ayu Toyota and ... Maltamo, M.; Malinen, J.; Packalen, P.; Suvanto, A & Kangas, J (2006) Nonparametric estimation of stem volume using airborne laser scanning, aerial photography, and stand-register data Canadian ... Teak Plantations in Comparison with Seasonally Dry Tropical Forests in Thailand 209 Masamichi Takahashi, Dokrak Marod, Samreong Panuthai and Keizo Hirai Chapter 10 Fertility, Microbial Biomass...

Ngày tải lên: 28/06/2014, 09:20

... crack users: viral detection on crack paraphernalia Eur J Gastroenterol Hepatol 2008, 20:29-32 Haydon E, Fischer B: Crack use as a public health problem in Canada: call for an evaluation of 'safer ... in manuscript writing JBa reviewed qualitative interviews and assisted in manuscript writing All have read and approved the final manuscript Acknowledgements We are grateful to Carolin Timms and ... supplies distributed An invitation letter was sent to the contact at each selected site A research assistant contacted potential participants to arrange an approximately one-hour in-person interview...

Ngày tải lên: 11/08/2014, 18:20

... Laniado S, Schwartz D, Yachnin T, et al.: The use of subcutaneous erythropoietin intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac ... failure improves cardiac and renal function and functional cardiac class and markedly reduces hospitalization J Am Coll Cardiol 2000, 35:1737-1744 Ehrenreich H, Hasselblatt M, Dembowski C, Cepek ... Cerami A: Erythropoietin crosses the blood brain barrier to protect against experimental brain injury Proc Natl Acad Sci USA 2000, 97:10526-10531 Liu XZ, Xu XM, Hu R, Du C, Zhang SX, McDonald...

Ngày tải lên: 12/08/2014, 20:20

... to thank my seniors and labmates in Tissue Modulation Laboratory, who have not only saved a first year graduate student from many crises and disasters in lab, but more importantly, have also made ... Rabbit polyclonal Secondary Antibodies S34253 A1 1072 TIE-2 488 goat anti mouse 594 goat anti rabbit Cat No Format Primary Antibodies Mature Pericyte Markers AB32570 Rabbit monoclonal AB5320 Rabbit ... rehydrated by a series of xylene, ethanol and water washes, and then stained with Alcian Blue and Fast Red which stain for sulfated glycosaminoglycans and nuclei, respectively Ficoll was added...

Ngày tải lên: 02/10/2015, 17:13

... between a portrait and a landscape (Dorfman, 2003) In a news story framed as a portrait, audiences may learn a great deal about an individual or an event, with great drama and emotion But it is hard ... discipline, and hard work are seen as dominant factors, reinforcing individualism A shift to social justice demands a rebalancing of these values with others that Americans also hold (Wallack & Lawrence, ... presumably attract a larger audience FRAMING PUBLIC HEALTH Public health issues, such as tobacco, alcohol, guns, and traffic safety, have all experienced a transition from a focus on behavior to attention...

Ngày tải lên: 14/02/2014, 13:20

... discriminative additional pay were more easily manipulated or negated through managers’ actions, and therefore full payout was less certain than if stars’ base salaries were simply raised As for ... star players of the teams they nominally ran As the manager’s autocracy waned, more clubs also hired an additional nonplaying coach to improve players’ performance and provide a less threatening ... , to an escalating stipend equal to the average player share They also lamented the escalation of on-field violence and player threats as their pay in relation to that of the latter had fallen...

Ngày tải lên: 23/03/2014, 22:20

... Quality Management Aligned with PMI Practice Standards International Project Management Management of Major Programs Hot! Strategic Management for Project Professionals PMP Exam Preparation Team-based ... waterfall approach is that you are able to define all aspects of a software project at its outset The iterative and agile approaches maintain that this premise does not hold up in an era of rapid ... Project Management • IT Management • Management Information Systems Master of Science in Management • Acquisition Management • Criminal Justice Administration • General Management • Project Management...

Ngày tải lên: 29/03/2014, 23:20

... simply emerged as a practical way to keep track of an organization’s resources Entering transactions twice provides a check to ensure computational accuracy and allows managers to track asset ownership ... ownership: A notable example was RJR Nabisco’s extravagant 1980s spending on a corporate aircraft fleet Investors and creditors fashioned contracts from financial accounting balances in attempts to align ... entry The manager had learned that a client had amassed a sizable bond position and sustained adverse interest rate changes Financial statements recently filed with the Securities and Exchange Commission...

Ngày tải lên: 30/03/2014, 14:20

... and protozoa can cause parasitic brain abscesses, but these are rare Clinical presentation Patients with brain abscess may present a myriad of complaints including headache, mental status changes, ... gastrointestinal examination However, on neurological examination, he was lethargic, and found to have dysarthria and ataxia A computed tomography (CT) scan was immediately ordered CT scan Figure - Coronal ... both ears, with bulging tympanic membranes and decreased light reflex The throat was normal The lungs were clear to auscultation bilaterally, and the heart exam was unremarkable He had a soft and...

Ngày tải lên: 21/06/2014, 02:20

... furfural, and acetoin act as external electron acceptors during anaerobic fermentation of xylose in recombinant Saccharomyces cerevisiae Biotechnol Bioeng 78(2):172–178 Watanabe S, Abu Saleh A, Pack ... this article as: Olofsson et al.: A mutated xylose reductase increases bioethanol production more than a glucose/xylose facilitator in simultaneous fermentation and co-fermentation of wheat straw ... xylose catabolism from transport to downstream catabolic reactions The mXR mutant has a higher Vmax and higher NADH/NAPH selectivity ratio, which was shown to directly relate to increased anaerobic...

Ngày tải lên: 21/06/2014, 05:20

Ngày tải lên: 23/06/2014, 00:20

... erythematosus syndrome [6] 71 Arthritis Research & Therapy Vol No Costedoat-Chalumeau et al Morphological heart abnormalities and anti-SSA/Ro antibodies Cardiac malformations Classically, autoantibody-mediated ... 13:760 Cimaz R, Meroni PL, Brucato A, Fesstova VV, Panzeri P, Goulene K, Stramba-Badiale M: Concomitant disappearance of electrocardiographic abnormalities and of acquired maternal autoantibodies ... data from therapeutic abortions, are needed for the correct evaluation of the frequency of major anatomic heart abnormalities associated with anti-SSA/Ro, but physicians should already be aware...

Ngày tải lên: 09/08/2014, 06:22

... Yang LP, Saah A, Hoover D: Maternal vitamin A deficiency and infant mortality in Malawi J Trop Pediatr 1998, 44(4):232-234 Semba RD, Miotti PG, Chiphangwi JD, Liomba G, Yang LP, Saah AJ, Dallabetta ... factorial trial assessing the impact of vitamin A, and of multivitamins excluding Vitamin A, on vertical transmission of HIV-1 and child mortality on pregnant women in Dar es Salaam, Tanzania (n = ... quality of life of patients, but also a human rights imperative [32] Specific trials aimed at women with low nutritional status may provide an additional armament in the fight against HIV/AIDS...

Ngày tải lên: 10/08/2014, 05:20

... including a considerable variety of cyanobacteria is available They comprise almost all phyla and classes of eukaryotic algae, but an emphasis is put on algae from freshwaters and terrestrial habitats ... significance tests (Non-Parametric Multivariate Analysis of Variance, Analysis of Similarity) and visualised as ordinations from multigroup discriminant analysis (Canonical Variates Analysis) ... three algal eukaryotic supergroups (Plantae, Chromalveolates, Excavates/Euglenoids) as based on fatty acid distribution patterns of 373 investigated cyanobacterial and algal strains using Canonical...

Ngày tải lên: 11/08/2014, 11:21

... these small RNAs are generated from doublestranded RNA, they are known as small interfering RNAs (siRNAs); however, if these small RNAs are produced from within the cell as natural RNAs that fold ... activation of the JAK/STAT (Janus kinase/signal transducer and activator of transcription) pathway and global up-regulation of interferon-stimulated genes This process is regulated in part by ... Johnson KL, Garcia-Sastre A, Ball LA, Palese P, Ding SW: Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing Proc Natl Acad Sci U S A 2004, 101:1350-1355...

Ngày tải lên: 13/08/2014, 09:21