morbid obesity and chronic intra abdominal hypertension

... with intraperitoneal cisplatin and adrenaline were definitively cured, whereas those treated with intraperitoneal cisplatin alone had only a delay in tumor growth [18] In two phase I studies, intraperitoneal ... treated 21 days after intraperitoneal cell inoculation Laparotomy was performed in anaesthetized rats (isoflurane inhalation as induction and then 100 mg/kg of intramuscular ketamine and 15 mg xylazine ... sampled and kept at -80° C until the platinum assay The comparison of groups and should assess the effect of hyperthermia; that of groups and should assess the effect of adrenaline; and that...

Ngày tải lên: 10/08/2014, 10:20

... transfusions and all medication was stopped apart from the intravenous insulin and intravenous fluids His haemoglobin increased, reticulocytes count rose and serum creatine kinase and bilirubin ... was calculated as 422 mmol/l and the diagnosis revised to diabetes mellitus with hyperosmolarity and acidosis The rate of intravenous insulin was reduced to U/hour and intravenous fluids changed ... electrolytes and renal function normalised but CRP increased to 350 mg/l and ceftriaxone and metronidazole were started for presumed aspiration pneumonia Clinically the patient improved and began...

Ngày tải lên: 11/08/2014, 23:21

... discomfort Immediately (0 h) and 24 h after perfusion, mice were euthanized and tumors, kidneys, liver, spleen, heart and brain were dissected and snap frozen in liquid nitrogen and stored at -80°C until ... cancer patient and sodium Figure Murine hyperthermic intraperitoneal chemotherapy model A Drawing of tumor bearing mouse undergoing HIPEC Depicted are inlet (a) and outlet (b) ports and anal temperature ... recorded every 15 and remained stable within 1°C throughout the 60 perfusion (Table 1) Platinum and arsenic accumulation and retention in metastatic tumors We determined Pt and arsenic accumulation...

Ngày tải lên: 20/06/2014, 07:20

... substrate and the base liquid was allowed to evaporate Magnetic Hysteresis loops of SPIONs were measured at room temperature and at a low temperature of K and are depicted in Fig Field-cooled (FC) and ... electrostatic and steric effects and could easily get conjugated to iron oxide particles Iron oxide is most recommended because of its higher magnetization values, lesser toxicity [19] and the ease ... 500Oe in the range 100–900 kHz Results and Discussion The fluid synthesized exhibited good shelf life and stability against sedimentation under gravitational and magnetic fields Fluid when an external...

Ngày tải lên: 21/06/2014, 07:20

... infections and rapid breathing Lower-esophageal temperatures closely reflect core temperature Tympanic membrane (TM) thermometers measure radiant heat from the tympanic membrane and nearby ear canal and ... then rises by ~0.6°C (1°F) with ovulation and remains at that level until menses occur Body temperature can be elevated in the postprandial state Pregnancy and endocrinologic dysfunction also affect ... raised, neurons in the vasomotor center are activated and vasoconstriction commences The individual first notices vasoconstriction in the hands and feet Shunting of blood away from the periphery...

Ngày tải lên: 06/07/2014, 12:20

... prescription psychotropic drugs and illicit drugs Drug-induced hyperthermia may be caused by monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and amphetamines and by the illicit use of ... bedridden, persons taking anticholinergic or antiparkinsonian drugs or diuretics, and individuals confined to poorly ventilated and non-air-conditioned environments are most susceptible.Drug-induced hyperthermia ... typically occurs in individuals exercising at elevated ambient temperatures and/ or humidities In a dry environment and at maximal efficiency, sweating can dissipate ~600 kcal/h, requiring the...

Ngày tải lên: 06/07/2014, 12:20

... cytokine is encoded by a separate gene, and each pyrogenic cytokine has been shown to cause fever in laboratory animals and in humans When injected into humans, IL-1 and TNF produce fever at low doses ... inflammatory, and hematopoietic processes For example, the elevated leukocytosis seen in several infections with an absolute neutrophilia is the result of the cytokines interleukin (IL) and IL-6 Some ... intravenously into volunteers, a dose of 2–3 ng/kg produces fever, leukocytosis, acute-phase proteins, and generalized symptoms of malaise Pyrogenic...

Ngày tải lên: 06/07/2014, 12:20

... receptors are called Toll-like receptors and are similar in many ways to IL-1 receptors The direct activation of Toll-like receptors also results in PGE2 production and fever Production of Cytokines ... CNS Several viral diseases produce active infection in the brain Glial and possibly neuronal cells synthesize IL-1, TNF, and IL-6 CNTF is also synthesized by neural as well as neuronal cells What ... OR HYPERTHERMIA Physical Examination Attention must be paid to the chronology of events and to other signs and symptoms preceding the fever The temperature may be taken orally or rectally, but...

Ngày tải lên: 06/07/2014, 12:20

... brucellosis, leptospirosis, some drug-induced fevers, and factitious fever In newborns, the elderly, patients with chronic renal failure, and patients taking glucocorticoids, fever may not be ... of an unusual febrile disease For example, the usual times of peak and trough temperatures may be reversed in typhoid fever and disseminated tuberculosis Temperature-pulse dissociation (relative ... period and then a relapse of days of fever In the Pel-Ebstein pattern, fever lasting 3–10 days is followed by afebrile periods of 3–10 days; this pattern can be classic for Hodgkin's disease and...

Ngày tải lên: 06/07/2014, 12:20

... indicated in the neuroleptic malignant syndrome and in drug-induced hyperthermia and may even be useful in the hyperthermia of the serotonin syndrome and thyrotoxicosis The neuroleptic malignant ... et al: Beneficial response to anakinra and thalidomide in Schnitzler's syndrome Ann Rheum Dis 65:542, 2006 Dinarello CA: Infection, fever, and exogenous and endogenous pyrogens: Some concepts ... 2002 [PMID: 12075060] Chandrasekharan NV et al: COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression Proc Natl...

Ngày tải lên: 06/07/2014, 12:20

... thermal perception and are more susceptible to immobility, malnutrition, and systemic illnesses that interfere with heat generation or conservation Dementia, psychiatric illness, and socioeconomic ... surface-to-mass ratio and their lack of effective shivering and adaptive behavioral responses In addition, malnutrition can contribute to heat loss because of diminished subcutaneous fat and because of ... loss), reduces thermogenesis and gluconeogenesis, and may impair judgment or lead to obtundation Phenothiazines, barbiturates, benzodiazepines, cyclic antidepressants, and many other medications...

Ngày tải lên: 06/07/2014, 12:21

... n; oxygen triiodot apathy; vasoconstri consumptio hyronin n; e and ia; increase in bronchorrhe thyroxin impaire cardiac d output and bronchospa increase judgme blood in a; ased increase preshiverin ... dioxide flow; thermogene production renal sis; rigidity and decrease in in renal shivering- depressi increased on increase diminishing of atrial and per level of ventricular 8°C autoreg drop in ulation ... motion; (82.4°F cerebro decrease in congestion ) vascula blood and edema; blood nerve- r pressure, 75% conduction autoreg heart ulation; and cardiac oxygen decreas decline output; re- consumptio e...

Ngày tải lên: 06/07/2014, 12:21

... evidence of intravascular thrombosis with a fibrinogen value < 0.5 g/L (

Ngày tải lên: 06/07/2014, 12:21

... is best accomplished with forced-air heating blankets Other options include radiant heat sources and hot packs Monitoring a patient with hypothermia in a heated tub is extremely difficult Electric ... provides less heat than some other forms of active core rewarming, it eliminates respiratory heat loss and adds 1°–2°C to the overall rewarming rate Crystalloids should be heated to 40°–42°C, but the ... provided is significant only during massive volume resuscitation The most efficient method for heating and delivering fluid or blood is with a countercurrent in-line heat exchanger Heated irrigation...

Ngày tải lên: 06/07/2014, 12:21

... most of the symptoms and signs of infection, notably fever and leukocytosis Shaking rigors from infection may be mistaken for shivering Except in mild cases, extensive cultures and repeated physical ... arteriovenous shunting increases tissue pressures, and edema forms Finally, thrombosis, ischemia, and superficial necrosis appear The development of mummification and demarcation may take weeks to months ... with standard therapy The administration of parenteral levothyroxine to euthyroid patients with hypothermia, however, is potentially hazardous Because laboratory results can be delayed and confounded...

Ngày tải lên: 06/07/2014, 12:21

... trước thị giác vùng đồi thị Interleukin-1 kích thích trình tổng hợp prostaglandin nhóm E từ acid arachidonic Prostaglandin E mà đặc biệt PG-E1 kích thích trình tổng hợp adenyl monophosphat vòng ... tăng sản xuất prostaglandin E làm tăng trình sinh nhiệt ngược lại (aspirin dẫn xuất có tác dụng hạ sốt thông qua chế ức chế men cyclooxygenaza ngăn cản tổng hợp prostaglandin E1, E2 Glucocorticoid ... hạ nhiệt thông qua chế ức chế sản xuất interleukin-1 v.v ) Prostaglandin đặc hiệu CSN ngoại sinh CSN nội sinh (IL-1) Prostaglandin Acid arachidonic AMP vòng Hypothalamus (Dưới đồi) TB bắp tăng...

Ngày tải lên: 05/08/2014, 20:22

... strength in both his hands and his feet, but active lifting of his head, legs, and arms was barely possible while he was supine, and his speech was slurred His reflexes, eye movements, and cranial nerve ... creatinine 51 μmol/L, BUN 6.4 mmol/L, sodium 122 mmol/L, and potassium 4.3 mmol/L His serum 25OH vitamin D level and thyroid gland function were normal, and his human immunodeficiency virus test was negative ... Switzerland 2Emergency Department, University Hospital Bern, 3010 Bern, Switzerland Authors’ contributions MB and MR contributed equally to the case report Both of them wrote the report and conducted...

Ngày tải lên: 10/08/2014, 23:20

... anti-double-stranded DNA results were negative and serum complement (C3 and C4) levels were within normal limits HIV rapid test and serum antibody (IgM) tests for cytomegalovirus and Epstein Barr ... doctor in charge of our patient and revised the case report ER revised the case report CL and SS were consulting physicians and revised the case report All authors read and approved the final manuscript ... psychomotor development, and vaccinations had been given on schedule On physical examination, his vital signs were within normal limits and he was not febrile His weight was 13.6 kg and his height 98...

Ngày tải lên: 10/08/2014, 23:20

... intubated for airway protection and to facilitate endoscopy He was resuscitated with crystalloids, 5% albumin, packed cells and fresh frozen plasma and treated with vancomycin and piperacillin/ tazobactam ... occipital and parietal lobes bilaterally and pons Our patient’s clinical examination, together with the transcranial Doppler and neuroimaging studies suggested that he had severely increased intracranial ... lipoprotein membranes, reduction in the oxygen demand in low flow regions, reduction in intracellular acidosis, and inhibition of the biosynthesis, release, and uptake of excitatory neurotransmitters...

Ngày tải lên: 11/08/2014, 17:21