molecular mechanisms biological effects and therapeutic strategies of protection

... PROPHLACTIC AND THERAPEUTIC POTENTIAL OF SYNTHETIC PEPTIDES AGAINST ENTEROVIRUS 71 (EV71) DAMIAN FOO GUANG WEI NATIONAL UNIVERSITY OF SINGAPORE 2008 PROPHLACTIC AND THERAPEUTIC POTENTIAL OF SYNTHETIC ... vitro culturing and activation of dendritic cells (DCs) 64 CD4+ T cell selection and proliferation 65 Molecular biology 66 2.3.1 Design and synthesis of EV71-specific primers and probes 66 ... epidemic of aseptic meningitis and/ or hand, foot, and mouth disease. Lancet 1974;13:112. 6. Cello J, Samuelson A, Stålhandske P, Svennerholm B, Jeansson S, and Forsgren M: Identification of group-common

Ngày tải lên: 12/09/2015, 08:19

... characteristics of FHHs b) socio-economic background of FHHs and nature of problems c) age and marital status of female head d) educational status of female head e) tangible resource of FHHs f) intangible/social ... mostly widowed and abandoned by their husbands (21.7% and 22.5%, respectively). A third of the sample (34.1%) was married. These women were living with their disabled husbands, and in some cases, husbands ... systematic studies of the forms of vulnerable livelihoods in urban areas of Bangladesh. Hence, the present study will investigate the livelihood, constraints and coping strategies of the female heads of households

Ngày tải lên: 03/10/2015, 21:58

... perception of the existence of fair treatment in the workplace This typically consists of such factors as fairness in the selection of employees, evaluation of performance and distribution of rewards and ... talents and experience of them, and take the time to dig into it 5 Principles of fairness and equal treatment Recognition of fair and equitable treatment... employee and determine ... idea of the sustained presence of service is very important to understand the research environment In addition to benefits such as legal and mandatory provident fund and service, here is a list of

Ngày tải lên: 09/05/2016, 17:46

... laboratory and nursery of Thai Nguyen university of Agriculture and Forestry Structure of the study report Beside of introduction and conclusion, the report includes chapters: Chapter 1: Overview of ... nutrients for trees 3.3.3.1 Influence of minerals and nutrients on the growth of height and diameter of Phay species Influence of minerals and nutrients on growth of Phay species has shown in the ... large timber plantation protection and evaluation of growth and development of Phay... Influence of shading on amount of chlorophyll in Phay’s leaves Amount of chlorophyll (HLDL)

Ngày tải lên: 21/07/2016, 11:03

... probably due to the off-stoichiometry of Cr2CoGa and the existence of the disorders and phase separation II EXPERIMENTAL Cr2CoGa films with thickness of 60 nm were grown on Si(001) and GaAs(001) substrates, ... moment probably due to the off-stoichiometry of Cr2CoGa and the existence of phase separation and disorders In addition, the distinct difference between the in-plane and out -of- plane saturated magnetization ... the off-stoichiometry of Cr2CoGa and the existence of phase separation and disorders Moreover, the T2 dependence of magnetization has been previously observed in half-metallic Heusler alloys and

Ngày tải lên: 02/09/2017, 08:42

... Cross-Tabulation of Valuation of Job Title and Gender 56 4.16 Cross-Tabulation of Valuation of Job Title and Age 57 4.17 Cross-Tabulation of Valuation of Job Title and Education 58 4.18 Result of the Logistic ... Valuation of Job Title and the Satisfaction from Benefits 49 4.9 Cross-Tabulation of Work Satisfaction and Gender 50 4.10 Cross-tabulation of Work Satisfaction and Age 51 4.11 Cross-Tabulation of Work ... Satisfaction and Education 52 4.12 Cross-Tabulation of Emotional Attachment and Gender 53 4.13 Cross-Tabulation of Emotional Attachment and Age 54 4.14 Cross-Tabulation of Emotional Attachment and Education

Ngày tải lên: 02/10/2017, 09:03

... realizations of direct and indirect strategies of politeness are associated with two types of strategies of face threatening acts (FTAs), namely bald-on-record and offrecord strategies The off-record ... bald-on-record and off-record strategies proposed by Brown and Levinson in the hope of finding out to what extent the characters’ strategies of politeness differ from social expectations of polite speech and ... directness and indirectness strategies in the light of Brown and Levinson’s politeness theory These strategies include the bald-on-record and the off-record strategies, with the focus on the use of rhetorical

Ngày tải lên: 10/01/2020, 05:02

... co-deletions of chromosomes 1p and 19q [20] Different patterns of the IDH1 mutation between primary and secondary GBM, as well as between other grades of astrocytomas, and between other types of gliomas, ... inclusion of temozolomide to surgery and radiotherapy resulted in a median survival of 15 months, 2.5 months more than surgery and radiation alone, and this regimen has become the current standard ... type of astrocytoma, representing 55% of all cases of glioma GBM treatment has traditionally involved surgery and radiation, with chemotherapy being of little additional value [2] A recent randomized

Ngày tải lên: 15/01/2020, 20:25

... metabolic profiles in response to salt and alkali stress Based on the comparison results of metabolic profiles and SPAD values between salt stress and alkali stress, the harmful effects of alkali ... concentration and fold changes of 75 metabolites in leaves of wheat seedlings after 15 days of salt and alkali treatment The relative concentration of each metabolite is an average of data from five biological ... concentration and fold changes of 75 metabolites in roots of wheat seedlings after 15 days of salt and alkali treatment The relative concentration of each metabolite is an average of data from five biological

Ngày tải lên: 26/05/2020, 21:36

... kg/hm2 K2SO4, and 15 kg/hm2 ZnSO4 The control and treatment groups were randomized based on a block design of three replications with a seeding rate of 22.5 kg/hm2 and spacing of 20 cm The developing ... in protein synthesis and the folding, assembly, transport, and secretion of nascent proteins [1] One of the most important functions of the ER involves the quality control of nascent proteins, ... complexes [21] Expression profile of TaBiP genes in different wheat organs Expression profiles of the three obtained TaBiP genes in the roots, stems, leaves, and seeds of wheat were investigated

Ngày tải lên: 27/05/2020, 01:23

... width and TKW Here, we mainly analyzed haplotypes of TaGW2-6B and their effects on TKW and interaction with haplotypes at TaGW2-6A Results: About 2.9 kb of the promoter sequences of TaGW2-6B and ... focused on sequencing and diversity studies of the promoter regions of TaGW26B and TaGW2-6D, functional marker development, and Page of 19 an expression pattern comparison of the three homoeologous ... of Crop Gene Resources and Germplasm Enhancment, Ministry of Agriculture/The National Key Facility for Crop Gene Resources and Genetic Improvement/Institute of Crop Science, Chinese Academy of

Ngày tải lên: 27/05/2020, 01:46

... ZE-4c, ZE-5a and ZE-5b inhibited arachidonic acid, adenosine diphosphate and collagen-induced platelets aggregation with ­IC50 values of 40.1, 785 and 10.01 (ZE-4b), 55.3, 850.4 and 10 (ZE-4c), ... Amir Badshah1, Arif‑ullah Khan1*, Humaira Nadeem1 and? ?Sagheer Ahmed2 Abstract  In the present study, a series of new hydrazone and sulfonamide derivatives of 1,2,4-triazole were synthesized Initially ... by FTIR, 1HNMR, 13CNMR and elemental analysis data Furthermore, the new hydrazone and sulfonamide derivatives ZE-4(b–c) and ZE-5(a–b) were evaluated for their antiplatelet and anticoagulant activities

Ngày tải lên: 29/05/2020, 12:48

... rise above 140 mg/dL The focus of this thesis is to understand the molecular mechanisms of insulin-mediated glucose transport into adipose tissue and skeletal muscle and how this process becomes ... the Food and Nutrition Board of the Institute of Medicine of the National Academy of Sciences, 34 the adequate intake of chromium is set to 30 µg/d (243) Given the known absorption of chromium ... caloric intake and/ or obesity currently remain the largest predisposing risk factors for the development of type diabetes Discerning the cellular and molecular mechanisms responsible and amendable...

Ngày tải lên: 24/08/2014, 10:54

... template-assembly approach requires a complex and carefully planned protocol of orthogonal protection and deprotection strategies to ensure proper coupling and parallel growth of several peptide chains onto ... inhibition of Hep3B and L929 cell adhesion to collagen Cell adhesion to native and denatured collagen and PT-assembled collagen-mimetic peptides Cytoskeletal organization and focal adhesion immunofluorescence ... ε-amino group of a protein-bound lysine (K donor group) results in the formation of intermolecular isopeptide ε-(γ-glutamyl)lysine crosslink (Lorand and Graham, 2003; Esposito and Caputo, 2004)...

Ngày tải lên: 12/09/2015, 08:20

... Reimer W: Costs of stroke and stroke services: Determinants of patient costs and a comparison of costs of regular care and care organised in stroke services Cost Effectiveness and Resource Allocation ... Selection of outcome measures The economic evaluation compares lifetime health effects and costs of the stroke service as compared to usual stroke care Health effects Lifetime health effects were ... patient and each place of Page of 10 residence (hospital, nursing home, revalidation centre and home) at which the patient stayed during this period, weighted by the length of stay Costs of care...

Ngày tải lên: 25/10/2012, 10:35

... (rooftop of Sumida-ku Ward Office as catchment area) and communal RWH called ‘rojison’ - 190 - Journal of Water and Environment Technology, Vol 9, No.2, 2011 From the interviews with Sumida-ku officers, ... promote sales of SWT devices □ Coincidence of TMG's request for the development of SWT devices to the makers with strategies of makers out of Tokyo Metropolis □ Cost consciousness of industrial ... policy makers and end-users) Journal of Water and Environment Technology, Vol 9, No.2, 2011 Mandatory Scheme The introduction of WWR and cumulative charging system are considered as mandatory schemes,...

Ngày tải lên: 05/09/2013, 10:17

... aggregates and cells, and the response of cells to the presence of aggregates [14,31] According to our previous data, the differing extent of alterations in ROS and free Ca2+ in IMR90 and Hend ... lack of LDH release from both Hend and IMR90 cells exposed to aggregates Mechanisms of apoptotic death in exposed cells Fig Time course of ATP levels in exposed cells and determination of MTP ... by later activation of caspase In IMR90 cells only moderate activation of caspase was found as a consequence of the modest activation of caspase and the lack of activation of caspase (Fig 7A)...

Ngày tải lên: 16/03/2014, 13:20

... safety and efficacy of cell therapy products The greater the understanding of the biology of stem cell self-renewal and differentiation, the more precise the evaluation and prediction of potential ... Advances in identification of the optimal characteristics of the matrix and an increased understanding of interactions between cells and biomaterials will condition development of future cell therapy ... wide range of development of new drugs and new procedures for the treatment of a great number of human diseases At least 5-10 years will elapse until these products, not therapeutic yet and under...

Ngày tải lên: 18/06/2014, 16:20

... Care and Use Committee of UCI and were in accordance with the guidelines of the National Institutes of Health Page of 15 viruses was confirmed by RT-PCR and restriction/ sequence analysis of the ... surface of VLP in a repetitive and ordered array Such organization of the epitope may induce T cell-independent B cell activation and production of anti-Ab antibodies of IgM isotype On the other hand, ... analyses and interpretation of data and statistical analysis She helped to draft the manuscript RC participated in preparation of chimeric viruses, purification of viral proteins and performing of...

Ngày tải lên: 18/06/2014, 22:20