molecular and clinical aspects

... and L Coiffard Chapter Malignancy in Relation to Autoimmune Blistering Dermatoses: Molecular and Clinical Aspects 159 Paweł Pietkiewicz, Justyna Gornowicz-Porowska, Monika BowszycDmochowska and ... both, age-specific and crude rates, and the standardized incidence rates (per the population of 100 000) with the use of a direct method and “the world’s population” as a standard [9] The cumulative ... standardized rate (World Standard Population) Cumulative – cumulative risk (0-74 years) Table Age-specific, crude and age-standardized incidence rates of cutaneous melanoma (C43) among men and...

Ngày tải lên: 23/03/2014, 22:20

... Teck, Zhao Wenwen, and many others Importantly, I want to thank my parents, family, and friends, who have supported me My fianc`e Marissa Iskandar for her continuous support e and prayer Their presence, ... bacterial species, and thus unravelling the DNA organisation modes of H-NS, H-NS-family proteins, and proteins that can antagonize gene silencing are key to better understand the molecular mechanism ... proteins, and our work will focus mainly on H-NS and H-NS-family proteins To be more specific, first we would like to gain better understanding on the mechanism of gene regulation by H-NS and H-NS-family...

Ngày tải lên: 09/09/2015, 11:26

... of gratitude for his support and encouragement, for his enlightening teachings and guidance, and for his invaluable mentorship and friendship He has created a unique and yet conducive environment ... family and a subunit encoded by the DP family of genes 43 In mammalian cells, there are six E2F genes (encoding E2F1, E2F2, E2F3, E2F4, E2F5 and E2F6) and two DP genes (encoding DP1 and DP2) E2F and ... of Molecular Nephrology and Gene Regulation, who made the lab such an enjoyable place to work and learn Special thanks to fellow colleagues Sharon Thio, Christopher Yang, Shahidah, Jit Kong and...

Ngày tải lên: 16/09/2015, 17:12

... marker protein), and CYP2E1 (C) Mitochondria of yeast cells expressing wild-type CYP2E1 were treated with bicarbonate, and both the soluble and insoluble fractions were separated and analyzed by ... as above 5¢ BamH1 sense and 3¢ HindIII antisense primers were used to amplify the su9-DHFR and cloned into the same sites of yeast vector pNS61 was cut with Spe1 and Xho1 and cloned into same sites ... excitation and emission wavelengths of 528 nm and 590 nm, respectively The ERND activities of mitochondria and mitoplast fractions expressing yeast CYP1A1 were measured as described by Anandatheerthavarada...

Ngày tải lên: 18/02/2014, 16:20

... (first lane), band to TbPEX14-N,H (last lane), band to the complex formed by the two proteins (lane 3), and bands and correspond to noncomplexed TbPEX5 and TbPEX14-N,H, respectively (lane and 5) association ... single band detected has the molecular mass of the PEX14 fragment and was absent from noninduced bacteria The anti-ALD Ig were purified on Protein A beads, coupled with AlexaFluorTM 488 (Molecular ... association of the proteins TbPEX5 and TbPEX14-N,H (Fig 1) The proteins were mixed and incubated for 30 before subjected to electrophoresis In lanes and (Fig 1A), TbPEX5 and TbPEX14-N,H alone were,...

Ngày tải lên: 23/03/2014, 17:21

... between Plk1 and CHMP6, CHMP4B, CHMP3 and CHMP2A (all ESCRT-III) Furthermore, interactions were demonstrated between CDC14A and CHMP4B and CHMP2A 4 These results indicate that polo kinase and Cdc14 ... subcellular localisation and functions CDC14A localises to the centrosomes during interphase and at the spindle midzone and midbody during mitosis and cytokinesis On the other hand, CDC14B is found ... analysis of Clp1p and the ESCRT proteins 99   Table 3.6: A summary of physical interactions between the ESCRT proteins and Plo1p and Clp1p 100   Chapter Table 5.1: Genetic and physical...

Ngày tải lên: 22/12/2014, 17:54

... labmates, both past and present, for making the lab such a lively place To my friend and flatmate, Dr Andrea Lisa Holme for her encouragements during the writing of this thesis and her help during ... anti-apoptotic Bcl-2 proteins 34 2.6.3 Simultaneous modulation of extrinsic and intrinsic pathways 35 2.7 Pre -clinical and clinical evaluation of TRAIL 36 2.7.1 Recombinant human TRAIL ... depolarization ("#m) and mitochondrial aggregation 88 LY30 and TRAIL treatment engages the mitochondrial apoptotic pathway 91 LY30 and TRAIL combined treatment induces, and is dependent on,...

Ngày tải lên: 11/09/2015, 10:14

... between the top of the gradient (monomers, dimmers and low molecular size oligomers) and fractions corresponding to a high molecular mass (Figure 29A and B) Interestingly, treatment with LY30 alone ... 1h Levels of cytochrome c and Smac in the mitochondrial and cytosolic fractions were then assayed by western blotting 92 LY30 and TRAIL combined treatment induces, and is dependent on, caspase ... combined treatment of TRAIL and LY30 was blocked by zVAD-fmk at 12h (Figure 18A, B and C) Moreover, specific inhibitors for caspase-3 and -8 activity (z-DEVD-fmk and z-IETD-fmk, respectively)...

Ngày tải lên: 11/09/2015, 10:15

... Xuhua, Dandan, Zhuang Ying, Chen Jing, Xin Gang, Wang Fan, Liu Yang, Jia Hai,…for their warm friendship and great help Thank God for bringing me here to Singapore and with His amazing grace and unfailing ... MICROBIAL PROTEASES AND PAMP IN THE ACTIVATION OF HMC/PPO AND HB INTO ROS PRODUCER 125 3.5.1 LTA itself can enhance production of ROS by HMC/PPO and metHb 125 3.5.2 PAMPs and proteases enhance ... HMC subunit and the view of the PO active site 22 Figure 1.9 The link between the horseshoe crab clotting and prophenoloxidase-activating systems and a comparison between the insect and crustacean...

Ngày tải lên: 12/09/2015, 08:16

... Understand Political Landscape  Types of Political Environments • Minimally Politicized Arena – power possessed by those  who are truthful and demonstrate regard for their own  outcomes and those of others ... an undesirable action plan Rule #11: Don’t Play Same Hand Twice  Develop extensive command of  negotiation strategies or a repertoire of  strategies and tactics  Don’t utilize the same tactic/strategy  ... Demonstrate recall & understanding of  information  Suggest an agenda      Rule #2: Do Your Research  Smart talk – sounding confident,  articulate or eloquent  Stay abreast of content areas and read  a broad range of materials...

Ngày tải lên: 22/08/2012, 22:07

... business and liquidity, and of short-term developments of demand and supply in the specific sectors and markets where enterprises operate Investment financial institutions, on the other hand, develop ... key players in recapitalization of banks; in Poland and Hungary foreign banks brought much needed know-how and capital; and in Argentina and New Zealand, foreign banks also brought fresh capital ... entry and sanctioning criteria, and ban discriminatory and unfair practices Government should also ensure that SRO rules and operations are not detrimental to small participants and consumers, and...

Ngày tải lên: 24/10/2012, 09:33

... Thi Thanh Xuan - Standing member • Mr Hoang Dang Doanh - Standing member • Mr Do Xuan Quang - Standing member • Mr Nguyen Giang Tien - Standing member 2.1.3 Statues and Standard Trading Conditions ... improve the transaction standards and the quality of business activities for enhancing the efficiency of export and import activities, expanding the external economic relations and co-operate with ... need to be renewed to facilitate export and import The General Department of Customs, the Ministry of Trade and examining bodies, and the Bureau of Standards and Measures should have consensus on...

Ngày tải lên: 27/10/2012, 16:42

... Seroprevalence of Toxoplasma gondii infection and risk factors associated with seropositivity of pregnant women in Korea J Parasitol 2008; 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases ... and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163 http://www.medsci.org ...

Ngày tải lên: 03/11/2012, 11:06

... language to influence and persuade those who have power and also because their languages, experiences and knowledge are down played in the new policies and technologies Conclusion and recommendations ... between the poor and rich, formal and non formal education and help people cope with political, economic and social changes adult education programs need to respond to language conflicts and inequalities ... and promotes Setswana and English at the expense of the other languages that exist in the country, the adult language program in Botswana maintains the hegemony and the gap between the poor and...

Ngày tải lên: 05/11/2012, 16:27

... use the card within demand deposit account balance and/ or overdraft for payments of merchandises or services or for cash withdrawal/advance and other services at ATM/EDC and other cash disbursement ... use the card within demand deposit account balance and/ or overdraft for payments of merchandises or services or 19 for cash withdrawal/advance and other services at ATM/EDC and other cash disbursement ... income and stable such as: petroleum, banking, telecommunication, aviation and private businesses increasingly make up bigger population They has high income and stable and also has needs and enough...

Ngày tải lên: 03/04/2013, 12:13

... tiền phải dựa sở nguời vay phải có khả trả cho người cho vay tương lai  Nhu cầu có khả toán(Demands): nhu cầu tự nhiên mong muốn hợp với khả mua sắm Nhà kinh doanh phát nhu cầu tự nhiên, mong ... cấp) thay văn phòng đại diện để trở thành Nhà phân phối thức  Tên giao dịch Quốc tế: Equipments and Values Development  Tên viết tắt: EVD, Co., Ltd  Trụ sở chính: Tầng – Số 10 – Lê Quý Đôn –...

Ngày tải lên: 08/04/2013, 17:01

... increase in sophistication and understanding of brand equity and advertising can be largely attributed to increased consumer exposure and understanding of both ads and branding 23 In an effort to ... different brands are on the store shelves and thousands of new products are introduced every year The opportunity to advertise new brands gives companies the incentive to develop new brands and improve ... selective demand Primary demand advertising is designed to stimulate demand for the general product class or entire industry; selective demand advertising focuses on creating demand for a particular...

Ngày tải lên: 16/04/2013, 11:05

... styles of women and men and concluded that some differences existed Eagly and Johnson (1990) found that male and female leaders performed similarly in both interpersonally oriented and task-oriented ... goals and missions of the organisation, and according to Mandell and Pherwani (2003), this awareness enables followers to look beyond their own interests, which subsequently benefits the group and ... approaches and their biases’’, Journal of Business Ethics, Vol 9, pp 267-74 Fielden, S.L and Davidson, M.J (1999), ‘‘Stress and unemployment: a comparative review and research model of female and male...

Ngày tải lên: 08/10/2013, 15:56

... Stimulating domestic demand and combating deflation by implementing a sound monetary policy; (7) Expanding the scope of financial service and initiating consumer credit market; and (8) The emergence ... will be expanded, with its decision-making mechanism improved and direction and intensity rationally decided and timely adjusted In terms of operations, we will increase trading frequency and introduce ... gradually advanced and an interest rate system with the central bank rate as benchmark and deposit and lending rates of financial institutions determined by market supply and demand of funds will...

Ngày tải lên: 18/10/2013, 07:15

Ngày tải lên: 25/10/2013, 05:20