... be the reference); 2, docked into the active site of the human DPP-IV; 3, docked into the active site of the crystalline structure of PepX from L. lactis;and4, docked into the active site of the ... Sites for the design of inhibitors of PepX activity FEBS Journal 272 (2005) 2050–2059 ª 2005 FEBS 2051 The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design ... 2). The interactions of the bound ligand with the resi- dues of the specificity site (Fig. 4A) reveal good stack- ing between the pyrrolidine ring of the drug and the side chain of Tyr380 (Pos1 subsite),...
Ngày tải lên: 23/03/2014, 13:20
... together to form long chains of -CH 2 - .[75] There has been disagreement over the exact reaction and order of the reactions since the 36 Figure 9: Product distribution for different α for the ... From the calculations derived in Appendix A, the energy demand for the modified pulping section of the plant is 56 MW of electricity and 267 tonnes per day of steam. The demand for the steam ... intermediate. The first part of the reaction from synthesis gas to methanol is quite exothermal and it is limited by equilibrium at a fairly low temperature. Therefore, the first part of the reaction...
Ngày tải lên: 26/02/2014, 14:20
Báo cáo khoa học: "THE DESIGN OF THE KERNEL ARCHITECTURE FOR THE EUROTRA* SOFTWARE" pptx
... on theoretically sound grounds, we argue that, given the state of the art, the only viable solution for the designer of software tools for MT, is to provide the linguists building the ... in charge of redesigning the system whenever new needs for the user arise. Therefore the part of the system that is visible to the linguistic user will be a system generator, rather than ... of an MT system. B. Computational Paradigm for MT Software The computational paradigm we have chosen for the systems to be generated is the one of expert systems because the design of software...
Ngày tải lên: 08/03/2014, 18:20
Biosecurity protocols for the prevention of spread of porcine reproductive and respiratory syndrome virus ppt
... Followingsanitation, the vehiclemustbeallowedadequatedryingtimeafter disinfection.Aswithfacilities,thisis the mostimportantstepin the sanitation protocoltocompletelyinactivate the virus. The use of highvolumewarmair candecrease the amount of timeneeded for drying. The thermoassisteddrying anddecontamination ... itoescanserveasmechanicalvectors of PRRSVandcan transport the virusatleast2.4kmfromaninfectedfarm. The site of retentiono f the virus in the flyis the GItractand the rate of viraldecayovertimeisinfluencedbyquantity ingestedandenvironmentaltemperature.Inordertopreventspread of PRRSVvia insects the followingstepsarer ... receivesemenvalidatedasPRRSV negativeinrealtimeandsafelyintroduceittotheirherds. Bloodtestingisoweangiltsinquarantine Indirectroutes PRRSVcanbemechanicallytransmittedinanumber of ways. The follow ing sectionwillreviewroutes of transmiss ionandoutline the biosecurity protocols designed tohelpprevent spreadviatheseroutes. 13 v Once the evacuationperiodisover,...
Ngày tải lên: 22/03/2014, 12:20
Windows Mobile Game Development: Building Games for the Windows Phone and Other Mobile Devices pdf
... and all of the devices for the new platform will CHAPTER 1 ■ WINDOWS MOBILE AND .NET 6 These emulators actually offer a full implementation of the emulated device and are capable of running ... with the rest of the device to avoid irritating your user. There are a number of things we can do to reduce the impact of this type of interruption: automatically pause the game if another ... Windows CE forms the underlying platform for Windows Mobile devices. These use many of the features and services provided by the core operating system, but add a significant amount of additional...
Ngày tải lên: 22/03/2014, 15:21
Báo cáo khoa học: "The Design of a Computer Language for Linguistic Information" ppt
... form of subject-verb agreement. Note that the process of unification is order-independent. For instance, we would get the same effect regardless of whether the unifications at the top of the ... requires that the agr feature of the DAG associated with the VP be the same as (unified with) the agr of the V. Thus, the VP's agr feature will have as its value the same node as the V's ... the application of the rule. The grammar rules describe how constituents can be built up to form new constituents with associated DAGs. The right side of the rule lists the cat values of the...
Ngày tải lên: 24/03/2014, 01:21
API - 2510A - Fire-Protection Considerations for the Design and Operation of Liquefied Petroleum Gas (LPG) Storage Facilities
... Þres: a. The time of the ÞreÕs inception if there is ßame impinge- ment or engulfment of the vessel. b. The liquid level in the storage vessel and whether it is above or below the area of ßame ... determination of the distance between the vessel and the center of the pool Þre at which the maximum incident heat ßux to the vessel shell surface will be at the critical value of 7000 British thermal ... holes to the side of the vessel or to grade. 2.10.2.4 The vertical stack from the valve should be sup- ported independently of the valve. Otherwise, the ßow reac- tion forces can impose stresses on the...
Ngày tải lên: 27/03/2014, 14:07
Báo cáo khoa học: "TENSE GENERATION IN AN INTELLIGENT TUTOR FOR FOREIGN LANGUAGE TEACHING: SOME ISSUES IN THE DESIGN OF THE VERB EXPERT" pot
... This information includes, for example, the kind of clause (main, coordinate, subordinate), whether the clause has a verb to be solved, the voice and form of the clause, the kind of event ... hypotheses about their causes. On the basis of these hy- potheses, the Tutor selects the next exercise which will test the student on the critical aspects pointed out so far and will allow the ... employed for producing it. At this point, the Student Modeler compares the answer of the student with that of the expert in order to identify the errors, if any, present in the former and to formulate...
Ngày tải lên: 01/04/2014, 00:20
Design for the Wisdom of Crowds
... Feedback getsatisfaction.com/apple Click! brooklynmuseum.org/exhibitions/click P2P File Sharing Putting It All Together Stock Market Thanks toothpastefordinner.com google.com/search?q=apple Change Jar Red vs Blue threadless.com/submission/197749 getsatisfaction.com/apple Seeing ... Emailed Stories Implicit Feedback Implicit Feedback Pageviews Searches Velocity Interestingness The End www.powazek.com flickr.com/photos/tags/apple/clusters amazon.com/product-reviews/B000BNI90Y ...
Ngày tải lên: 10/06/2014, 09:49
Báo cáo sinh học: " A critical assessment for the value of markers to gate-out undesired events in HLA-peptide multimer staining protocols" pot
... did the final approval of the manuscript. MK, MP, LMcN, TC, JY, KO and AH were driving the conception and design of the study, selected the donors for the study, interpreted the data and wrote the ... in collaboration with the CIC executive office and the steering committee of the CIC Immunoassay working group. The authors of this group acknowledge the con- cept of the Minimal Information About ... S2 Acknowledgements The organizers of this study are indebted to all the participating labs for their constant support of the proficiency panel program. The organizers also thank Beckmann Coulter and ProImmune for...
Ngày tải lên: 18/06/2014, 22:20
o cáo hóa học:" A critical assessment for the value of markers to gate-out undesired events in HLA-peptide multimer staining protocols" pot
... did the final approval of the manuscript. MK, MP, LMcN, TC, JY, KO and AH were driving the conception and design of the study, selected the donors for the study, interpreted the data and wrote the ... in collaboration with the CIC executive office and the steering committee of the CIC Immunoassay working group. The authors of this group acknowledge the con- cept of the Minimal Information About ... using the irrelevant MULTIMERS in four donors stratified by DUMP channel use and further subdivision by the use of dead cell marker. The table also indicates the number of labs (N) for each of the...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo hóa học: "A framework for ABFT techniques in the design of fault-tolerant computing systems" pot
Ngày tải lên: 20/06/2014, 22:20
Báo cáo hóa học: " Optimizing the design of nanostructures for improved thermal conduction within confined spaces" docx
Ngày tải lên: 21/06/2014, 03:20
Báo cáo hóa học: "Research Article WING/WORLD: An Open Experimental Toolkit for the Design and Deployment of IEEE " ppt
Ngày tải lên: 21/06/2014, 23:20
Báo cáo hóa học: " Research Article Interference Robust Transmission for the Downlink of an OFDM-Based Mobile Communications System" docx
Ngày tải lên: 22/06/2014, 06:20
Báo cáo hóa học: " Research Article Interference Robust Transmission for the Downlink of an OFDM-Based Mobile Communications " pptx
Ngày tải lên: 22/06/2014, 19:20
Báo cáo sinh học: "Optimal design for the detection of a major gene segregation in crosses" potx
Ngày tải lên: 09/08/2014, 18:21