... relationships of co-ordination (or parataxis – the linking of elements of equal status, the initiating and continuing elements are free) and subordination (or hypotaxis – the linking of elements of unequal ... many areas of English grammar It is called “functional” because of his development of the theory of the ideational, interpersonal, and textual metafunctions – functional components of meaning ... ideational, interpersonal, and textual Each of the three metafunctions is about a different aspect of the world, and is concerned with a different mode of meaning of clauses The ideational metafunction...
Ngày tải lên: 07/09/2013, 13:48
... grammatical and lexical cohesion analyses for the cohesive harmony of the text; to a summary of the context of situation of the text in terms of the three contextual parameters: field, tenor and ... in 20, don’t understand in 27, and don’t worry in 34) characterising the perception and feeling of the characters when they land in the new planet; and 7 are relational and existential processes ... total number of references, the number of clauses, the number of cohesive ties in the text and the number of ties per clause. The meaning and structure of a science fiction story: A sysyemic...
Ngày tải lên: 12/02/2014, 20:20
Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): reactivity and structure of metal–thiolate clusters* doc
... is a soft ligand and therefore shows a preference for soft metals. More- over the structures of metallothioneins are not rigid and hence there is little selectivity concerning the size of the ... determination of the spatial structure of the N-terminal domain con- taining the Cd(II) 3 -CysS 9 cluster was thus precluded. For a more detailed discussion of the dynamics of the protein structure and ... Cu(I) 4 ,Cu(I) 4 MT3 and Cu(I) 6 ,Cu(I) 6 MT3]. The determination of a 3D struc- ture seems crucial for understanding the differences between Cu–MT3 and Cu–MT1 ⁄ 2 (structure also not known) and the presence and...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Unusual metal specificity and structure of the group I ribozyme fromChlamydomonas reinhardtii23S rRNA pptx
... the P9 subdomains, most of P9 is protected, but most of P9.1 is neutral The 5¢ strand of P9.0 is protected despite the absence of the 3¢ strand For the idiosyncratic P7.1 and P7.2 domains, the ... P5, P6 and minor parts of P5a and P6a are protected Also, J4 ⁄ is weakly protected, but J5 ⁄ is weakly cleaved Of particular significance is the observed cleavage of J6 ⁄ and the neutrality of J3 ... three nucleotides of P7, and the 3¢-half of J8 ⁄ 7, are not protected The first three nucleotides of P7 are part of the G binding site, as are the terminal nucleotides of J6 ⁄ and J8 ⁄ [35–37];...
Ngày tải lên: 19/02/2014, 07:20
Báo cáo khoa học: Phosphorylation mechanism and structure of serine-arginine protein kinases pot
... SRPK1 and SRSF1, together with crystal structures of SRPK1 bound to peptide and pro- tein substrates and the recent structures of CLK1 and CLK3, suggest an elegant mechanism of recognition and ... sequential phosphorylation. X-ray structures of the kinase domains of CLK1 and CLK3 have been reported recently [41], and are G. Ghosh and J. A. Adams SRPK structure and mechanism FEBS Journal 278 ... ARTICLE Phosphorylation mechanism and structure of serine-arginine protein kinases Gourisankar Ghosh 1 and Joseph A. Adams 2 1 Department of Chemistry and Biochemistry, University of California, San Diego,...
Ngày tải lên: 15/03/2014, 00:20
Báo cáo hóa học: " Research Article The Methods of Hilbert Spaces and Structure of the Fixed-Point Set of Lipschitzian Mapping" docx
... Point Theory and Applications Volume 2009, Article ID 586487, 12 pages doi:10.1155/2009/586487 Research Article The Methods of Hilbert Spaces and Structure of the Fixed-Point Set of Lipschitzian ... that Fix T F and the Lipschitz constant of T tends to 1 if ε ↓ 0. For more information on the structure of fixed point sets see 4, 5 and references therein. In 1973, Goebel and Kirk 3 introduced ... techniques of asymptotic centers and the methods of Hilbert spaces, we establish some result on the structure of fixed point sets for mappings with lipschitzian iterates in a Hilbert space. The class of...
Ngày tải lên: 21/06/2014, 20:20
PHRASAL VERBS AND STRUCTURE OF ENGLISH
... dõi 1/ OF - ashamed of: xấu hổ về - afraid of : sợ , e ngại - ahead of : trớc - aware of : nhận thức - capable of : có khả năng - confident of : tin tởng - doubtful of : nghi ngờ - fond of : ... thích - full of : đầy - hopeful of : hy vọng - independent of : độc lập - proud of : tự h o - jealous of : ghen tị với - guilty of : phạm tội , có tội - sick of : chán nản về - joyful of : vui mừng ... 48.stand by : giữ lời hứa , sẵn sàng ủng hộ 49.stand for : đại diện cho , tha thứ 50.stand in for : thay thế cho 51.stand up to : chịu đựng ( chỉ vật ) 52.stand up for : bênh vực ai 53.stand...
Ngày tải lên: 06/07/2014, 03:00
Báo cáo y học: "Sequence and structure of Brassica rapa chromosome A3." pdf
... University of Queensland, Brisbane, QLD 4067, Australia 11Australian Centre for Plant Functional Genomics and School of Land Crop and Food Sciences, University of Queensland, Brisbane, ... 4 of 12 Figure 2 Distribution of various repeats and features on chromosome A3. The long arm of chromosome A3 is shown on the x-axis and is numbered from the beginning of contig 1 to the end of ... de Jong H, Bancroft I, Lim YP, Park BS: Characterization of the centromere and peri-centromere... Excellence for Integrative Legume Research and School of Land, Crop and Food Sciences,...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo sinh học: " History and structure of the closed pedigreed population of Icelandic Sheepdogs" pps
... Ballou and Lacy [6] as: where N is the number of candidates and f ij is the kinship between individual i and individual j. The mean kinship of an animal is a measure of the relationship of that ... dog of Scandinavia and contains 85% of the total population size. It includes the entire Norwegian and Finnish populations and almost every animal born in Sweden or Denmark, and a large part of ... Iceland (1654), Germany (153), Norway (774), Denmark (2241) and Finland (113). Pedigree data contained unique ID, father, mother, gender, date of birth, country of birth, and occasionally date of...
Ngày tải lên: 14/08/2014, 13:21
the meaning and structure of an american short story a systemic functional analysis = cấu trúc và ngữ nghĩa của một truyện ngắn mỹ
... tool and an effective method to help me understand the story further in terms of both meaning and structure 1.2 Aims and Scope of the Study Within the framework of a minor thesis, the aim of the ... distinct kinds of meaning that are embodied in the structure of a clause Each of these three strands of meaning is construed by configuration of certain particular functions Actor, Subject and Theme ... file supervised by Prof Dr Hoang Van Van such as: The meaning and Structure of a Biology text: a systemic functional analysis by Ho Thi Mai (2008); The meaning and structure of a fairy tale story:...
Ngày tải lên: 28/02/2015, 11:55
Particle Toxicology - Chapter 11 pot
... lungs of rats only occurs with DEP and not with carbon black (Ma and Ma 2002) The mechanisms of transfer of organic compounds from particles to the target cells can involve the uptake of particles ... extracts of DEP and PM increase IL-8, TNF and COX2 Organic extracts of DEP increase IL-8 Organic extracts of DEP did NOT alter costimulatory molecules (B7) and MHC class II (CDIa) expression and antigen ... 635–644, 1998 Ma, J Y and Ma, J K., The dual effect of the particulate and organic components of diesel exhaust particles on the alteration of pulmonary immune/inflammatory responses and metabolic enzymes,...
Ngày tải lên: 11/08/2014, 21:21
Báo cáo khoa học: Regulation of Cyr61/CCN1 gene expression through RhoA GTPase and p38MAPK signaling pathways Role of CREB and AP-1 transcription factors doc
... SRF of an, as yet, unidentified accessory factor [54] The regulation of c-jun is complex and may involve an increase in the levels of c-jun protein and/ or phosphorylation of specific serines (63 and/ or ... levels of CTGF/CCN2 peaked after h of incubation with S1P and decayed progressively thereafter These experiments revealed a stronger and earlier increase of Cyr61/CCN1 mRNA levels than those of Fig ... A-fos and A-ATF-2 proteins Immunodetection of endogenous c-fos and ATF-2 was performed with anti-c-fos and anti-ATF-2 Igs, respectively, using the same cell lysates Detection of K-CREB and endogenous...
Ngày tải lên: 08/03/2014, 08:20
Withdrawing from Iraq- Alternative Schedules, Associated Risks, and Mitigating Strategies potx
... behavior of the main opposition groups and their forces—i.e., al-Sadr and Jaysh al-Mahdi (JAM), the Sunni and the Sons of Iraq (SoI), and the Kurds and Summary xxv the Peshmerga and of the GoI and ... advising and assisting by the end of August 2010, and the military com2 Agreement Between the United States of America and the Republic of Iraq on the Withdrawal of United States Forces from Iraq and ... Reviewers of This Report Finally, we appreciate the thorough and thoughtful reviews of our four reviewers: RAND colleagues Lynn Davis and John Dumond, Michael O’Hanlon of the Brookings Institution, and...
Ngày tải lên: 23/03/2014, 02:20
Báo cáo khoa học: Liver receptor homolog-1 localization in the nuclear body is regulated by sumoylation and cAMP signaling in rat granulosa cells docx
... the effect of cAMP signaling on SUMO pathway is complex and cell type dependent Notwithstanding, the up regulation of E1, the down regulation of E2 or E3 and the increased expression of SENP2 lead ... incubating lL of in vitro 35S-labeled product with lg of Aos1 ⁄ Uba2, 150 ng of UBC9 and lg of SUMO-1 in sumoylation buffer (20 mm Hepes, pH 7.5, mm MgCl2 and mm ATP) SAE1 ⁄ SAE2, UBC9 and SUMO-1 ... lL of serum-free medium were placed in a mm cuvette (Bio-Rad, Hercules, CA, USA) A total amount of lg of DNA (2 lg of Myc-tagged LRH-1 expression plasmid, 1.5 lg of pDsRed-SUMO-1 and 1.5 lg of...
Ngày tải lên: 23/03/2014, 06:20
Erectile Dysfunction – Disease-Associated Mechanisms and Novel Insights into Therapy Edited by Kenia Pedrosa Nunes potx
... Changes of adrenal hormones The role of adrenal hormones and their changes are not well established in the etiology of ED Studies have correlated the low levels of dehydroepiandrosterone with ED Androstenedione ... molecular basis and mechanisms of ED have yet to be completely understood In the last decades, elucidation of the macroscopic structures of the erectile system 4-5 ushered in a new era of therapeutic ... innervations of the penis is both autonomic (sympathetic and parasympathetic) and somatic (sensory and motor) From the neurons in the spinal cord and peripheral ganglia, the sympathetic and parasympathetic...
Ngày tải lên: 23/03/2014, 17:20
Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx
... D19S425 and D19S418, at a distance of 32 centiRay (cR) [log of odds (LOD) score ¼ 6.47] and 29 cR (LOD score ¼ 6.28), respectively, and corresponded to an approximate physical distance of 960 and ... recruitment of SHP-1 and partial recruitment of SHP-2 The q FEBS 2001 recruitment of SHPs suggests that the function of siglec-10 is similar to that of other siglecs such as siglec-3/CD33 and siglec-7 ... spliced regions (S1 ¼ Ig domain and S2 ¼ Ig domain 5) of siglec-10 b-Actin was also probed as a control for mRNA integrity and loading washed and then twofold dilutions of the GST fusion proteins,...
Ngày tải lên: 24/03/2014, 04:21
báo cáo hóa học:" Bioactivity-guided identification and cell signaling technology to delineate the immunomodulatory effects of Panax ginseng on human promonocytic U937 cells" potx
... Cheng of Yale University and Prof Paul Tam of University of Hong Kong for their valuable advice and insightful comments We also thank Genome Research Centre of The University of Hong Kong for the ... of the suppressive effect of the PGSE on CXCL-10 induction, we measured the activities of MAP kinases, including ERK1/2 and p38MAPK, by Western analysis Intense activation of phospho-ERK1/2 and ... PGSE for 24 hours and followed by 20 units/ml of TNF-α for hours DNase-treated RNA samples were reverse transcribed and the levels of mRNA induction of (A) CXCL-10, (B) IL-8 and (C) TNFAIP3 as...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury" potx
... Better understanding of the improvement of neurological outcome with gelsolin may allow an in-depth understanding of the mechanisms by which gelsolin attenuates the acute response, and to what ... single dose of gelsolin can dramatically reduce mortality by ameliorating cerebral inflammatory lesions and apoptosis via acceleration of recruitment of monocytes and down-regulation of phospho-ERK1/2 ... manuscript, and participated in the writing of the manuscript QC participated in the design of the study and the preparation of the animal model JRK prepared all the cryostat sections LC and XMZ...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: " Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain" pptx
... activation of AMPK (Figure 3A) and a reversible inhibition of both ERK (Figure 3B and C) and mTOR signaling (Figure 3D–H) Hence, resveratrol dose- and time-dependently activates AMPK and inhibits ERK and ... activation of mTOR’s negative regulator, TSC2 [49] This results in a profound inhibition of mTOR and its downstream targets involved in translation control (e.g 4EBP and ribosomal S6 kinase and rS6p ... (Ser473, cat# 4058), total AKT, GAPDH and eIF4A Statistical Analysis and Data Presentation Data are shown as means and the standard error of the mean (± SEM) of eight independent cell culture wells,...
Ngày tải lên: 21/06/2014, 19:20
Associated Technologies And Milling Cutter by J Smith_2 doc
... effectiveness of the production process This latter point, not only influences method of component clamping, dictating: how, where and what will be the optimum method of ‘location and restraint’17 of the ... other important factors [Courtesy of Sandvik Coromant] Milling Cutters and Associated Technologies 163 Table 7: The ratio of cut width-to-diameter (W/D) Number of inserts in-cut Zc W/D: 0.88 0.80 ... life’ somewhat, but this is only part of the problem of off-centre cutting Returning to the cutter positioned centrally (i.e Fig 84g), here the direction of the radial component cutting forces...
Ngày tải lên: 21/06/2014, 21:20