microrna regulation in cardiovascular disease
gene therapy in cardiovascular disease
... generating in- creased collateral flow. But documented clinical success in reducing angina scoresand improving myocardial perfusion in otherwise untreatable patients has beenobserved. In a porcine ... GENE THERAPY IN CARDIOVASCULAR DISEASE in the affected area. Additionally, increased conversion of xanthine dehydrogenaseinto xanthine oxidase takes place. Upon exposure to oxygen during the period ... CARDIOVASCULAR DISEASE CHAPTER 8Gene Therapy in Cardiovascular Disease VICTOR J. DZAU, M.D., AFSHIN EHSAN, M.D., and MICHAEL J. MANN, M.D.INTRODUCTIONThe explosive growth in understanding the changes in...
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Báo cáo y học: "Hypoalbuminaemia – A Marker of Cardiovascular Disease in Patients with Chronic Kidney Disease Stages II - IV"
... 21. Levin A, Foley RN. Cardiovascular disease in chronic renal insufficiency. Am J Kidney Dis. 2003; 36: S24-30. 22. Danesh J, Collins R, Peto R. Lipoprotein (a) and coronary heart disease. ... is the reflection of inflammation induced malnutrition. The underlying mechanism be-hind this includes appetite suppression and increased catabolism by inflammatory cytokines (38). Cai and colleagues ... D. Cardiovascular disease and mortality in a community based cohort with mild renal insufficiency. Kidney Int. 1999; 56: 2214-19. 6. Shilpak MG, Fried LF, Crump C et al. Cardiovascular disease...
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Tài liệu Changing patterns of cardiovascular diseases and cancer mortality in Portugal, 1980--2010 docx
... gastro-intestinal diseases, injuries and poisoning, and infectious and parasitic diseases in the last three decades, in Portugal [10]. Since some of these causes of death are more common in the ... of disease came from cancers in men and from cardiovascular diseases in women. Keywords Cancer, Cardiovascular diseases, Mortality, Trends, Portugal Background In 2004, cardiovascular diseases ... significant change in the log-linear slope of the trend (joinpoints) [14]. The analysis starts with the minimum number of joinpoints (no joinpoints corresponds to a straight line), and tests...
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Urbanization and cardiovascular disease: Raising heart-healthy children in today’s cities pot
... are faced by individuals living in SSA in their ability to adopt heart-healthy lifestyles. Specifically, urban sprawl, including the lack of integrated planning, inadequate housing, poor water ... prevalence of heart disease has been increasing in China, partly as a result of a worsening profile of risk factors including increased prevalence of hypertension, smoking and obesity levels ... major in uence in the risk of CVD. 4.2.3.2 Tobacco useLevels of tobacco use in Brazil are declining. In 1989, the total prevalence of smoking was 34.8 per cent. In 2001, a survey of individuals...
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Báo cáo y học: "BRCA1 May Modulate Neuronal Cell Cycle Re-Entry in Alzheimer Disease"
... in all cases of Alzheimer disease. These findings not only further define the cell cycle reentry phenotype in Alzheimer disease but also indicate that the neurofibrillary tangles which define ... working with other factors to halt the cell cycle and mediate DNA repair. Interestingly, a much higher proportion of NFT were labeled in AD cases than in control cases. These findings hint ... fixed either in 10% buffered formalin or in methacarn (methanol:chloroform:acetic acid, 6:3:1), and embedded in paraffin. 6μm sections were depar-affinized in xylene and rehydrated in graded...
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Cell Cycle Regulation in Mammalian Germ Cells
... Connexin 43 These intracellular signaling molecules in their absence cause Juneja et al. 1999impaired folliculogenesis resulting in a germ cell deficiencywithin the gonads.Gja4/Cx37 Connexin 37 Intracellular ... absence of which results in vestigialelement binding protein ovaries with immature oocytes arrested at the pachytene stage.Dazla Dazla protein (Deleted in RNA binding protein that affects translational ... Chaperone protein involved in protein folding, Dix et al. 199670 kDa protein 2 (HSP70-2) leads to spermatogenic arrest at metaphase stage in knockouts.Cell Cycle Regulation in Mammalian Germ...
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Tài liệu Reading Our Lips: The History of Lipstick Regulation in Western Seats ... doc
... low in England during the nineteenth century, focusing only on lipstick in England could generate a most misleadingimage of lipstick’s global status. For example, during the same period in China, ... Members, 16 Law & Ineq. J. 661 (1998) (pointing out that: “a Marine recruit trainingmanual used after the Gulf War stated that female recruits would be given ‘instruction in hair care, techniques ... well as the continued complaining of religious writers,makes clear that lipstick remained at least relatively in use by females and entirely free from regulation oflaw.37 In Spain around 500...
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Tài liệu ESC Guidelines on the management of cardiovascular diseases during pregnancy pdf
... is in keeping with what is recommended in the guidelines,thus completing the loop between clinical research, writing ofguidelines, and implementing them into clinical practice.The guidelines ... CardiologyESC Guidelines 3195ESC GUIDELINESESC Guidelines on the management of cardiovascular diseases during pregnancyThe Task Force on the Management of Cardiovascular Diseasesduring Pregnancy ... an i.v. infusion of 5 mg/min,and gradually increased every 3–5 min to a maximum dose of100 mg/min.DeliveryInduction of delivery is indicated in gestational hypertension withproteinuria with...
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Tài liệu Cardiovascular Disease doc
... not exist in developing countries.Similarly, interventions that are cost saving in the United Statesmay not be cost saving in developing countries but may well becost-effective in terms of ... that have led to large increases in diabetesand hypertension. If these trends continue, age-adjusted CVDmortality rates could increase in the high-income countries in the coming years. These trends ... target oflipid-lowering therapy has been lowering total or LDL choles-terol, medical experts are increasingly recognizing the impor-tance of increasing HDL cholesterol and lowering triglyceridelevels,...
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Tài liệu Báo cáo khoa học: MicroRNAs and cardiovascular diseases ppt
... extracellularmatrix-related proteins involved in fibrosis, includingmultiple collagens, fibrillins and elastin [75]. miR-29 isdramatically repressed in the border zone flanking theinfracted area in the mouse model ... (Continued)miRNA TargetsGenesymbol FunctionBinding site in mouseConservation in mouseBinding sites in humanConservation in humanSNPs(dbSNP) ReferencesmiR-221 ⁄ 222 p27(Kip1) CDKN1B Inhibition ... mitogen-activated protein kinasesignaling pathway [76]. Upregulation of miR-21 in response to cardiac injury was shown to enhance extra-cellular signal-regulated kinase ⁄ mitogen-activated pro-tein kinase...
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Tài liệu Emotion Regulation in Couples and Families ppt
... domain playsan important role in maintaining good interpersonal relationships.Managing EmotionsBefore we discuss findings supporting the importance of managing emo-tions in ... areregulated intrapersonally (within individuals) than interpersonally (betweenindividuals). Investigators are only beginning to propose and test dyadicmodels specifying how the emotion regulation ... emotions, ranging from listening to musicto drinking caffeinated beverages to withdrawing from social interaction.Parkinson and Totterdell (1999) classified various emotion regulation...
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Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx
... in point, formation of huntingtin-containing inclusionbodies in Huntington’s disease encourages cell survival,whereas monomers and small inclusion bodies of hunt-ingtin, a protein possessing ... cells deficient in desmin, again demonstrating inclusion body construc-tion independent of intermediate fialments [62]. Inter-estingly, inclusion body formation is slowed byaB-crystallin, Hsp27 and ... aB-Crystallin R120 corresponds to aA-crystal-lin R116 and both are conserved a-crystallin domainarginines. R120G aB-crystallin permits intermediate fil-ament self association in vitro, although binding...
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