microrna regulation in cardiovascular disease

... generating in- creased collateral flow. But documented clinical success in reducing angina scores and improving myocardial perfusion in otherwise untreatable patients has been observed. In a porcine ... GENE THERAPY IN CARDIOVASCULAR DISEASE in the affected area. Additionally, increased conversion of xanthine dehydrogenase into xanthine oxidase takes place. Upon exposure to oxygen during the period ... CARDIOVASCULAR DISEASE CHAPTER 8 Gene Therapy in Cardiovascular Disease VICTOR J. DZAU, M.D., AFSHIN EHSAN, M.D., and MICHAEL J. MANN, M.D. INTRODUCTION The explosive growth in understanding the changes in...

Ngày tải lên: 10/04/2014, 22:11

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... 21. Levin A, Foley RN. Cardiovascular disease in chronic renal insufficiency. Am J Kidney Dis. 2003; 36: S24-30. 22. Danesh J, Collins R, Peto R. Lipoprotein (a) and coronary heart disease. ... is the reflection of inflammation induced malnutrition. The underlying mechanism be- hind this includes appetite suppression and increased catabolism by inflammatory cytokines (38). Cai and colleagues ... D. Cardiovascular disease and mortality in a community based cohort with mild renal insufficiency. Kidney Int. 1999; 56: 2214-19. 6. Shilpak MG, Fried LF, Crump C et al. Cardiovascular disease...

Ngày tải lên: 03/11/2012, 11:52

... gastro-intestinal diseases, injuries and poisoning, and infectious and parasitic diseases in the last three decades, in Portugal [10]. Since some of these causes of death are more common in the ... of disease came from cancers in men and from cardiovascular diseases in women. Keywords Cancer, Cardiovascular diseases, Mortality, Trends, Portugal Background In 2004, cardiovascular diseases ... significant change in the log-linear slope of the trend (joinpoints) [14]. The analysis starts with the minimum number of joinpoints (no joinpoints corresponds to a straight line), and tests...

Ngày tải lên: 15/02/2014, 04:20

... are faced by individuals living in SSA in their ability to adopt heart- healthy lifestyles. Specifically, urban sprawl, including the lack of integrated planning, inadequate housing, poor water ... prevalence of heart disease has been increasing in China, partly as a result of a worsening profile of risk factors including increased prevalence of hypertension, smoking and obesity levels ... major in uence in the risk of CVD. 4.2.3.2 Tobacco use Levels of tobacco use in Brazil are declining. In 1989, the total prevalence of smoking was 34.8 per cent. In 2001, a survey of individuals...

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Ngày tải lên: 20/06/2014, 03:20

... in all cases of Alzheimer disease. These findings not only further define the cell cycle reentry phenotype in Alzheimer disease but also indicate that the neurofibrillary tangles which define ... working with other factors to halt the cell cycle and mediate DNA repair. Interestingly, a much higher proportion of NFT were labeled in AD cases than in control cases. These findings hint ... fixed either in 10% buffered formalin or in methacarn (methanol:chloroform:acetic acid, 6:3:1), and embedded in paraffin. 6μm sections were depar- affinized in xylene and rehydrated in graded...

Ngày tải lên: 26/10/2012, 10:04

... Connexin 43 These intracellular signaling molecules in their absence cause Juneja et al. 1999 impaired folliculogenesis resulting in a germ cell deficiency within the gonads. Gja4/Cx37 Connexin 37 Intracellular ... absence of which results in vestigial element binding protein ovaries with immature oocytes arrested at the pachytene stage. Dazla Dazla protein (Deleted in RNA binding protein that affects translational ... Chaperone protein involved in protein folding, Dix et al. 1996 70 kDa protein 2 (HSP70-2) leads to spermatogenic arrest at metaphase stage in knockouts. Cell Cycle Regulation in Mammalian Germ...

Ngày tải lên: 25/10/2013, 21:20

... low in England during the nineteenth century, focusing only on lipstick in England could generate a most misleading image of lipstick’s global status. For example, during the same period in China, ... Members, 16 Law & Ineq. J. 661 (1998) (pointing out that: “a Marine recruit training manual used after the Gulf War stated that female recruits would be given ‘instruction in hair care, techniques ... well as the continued complaining of religious writers, makes clear that lipstick remained at least relatively in use by females and entirely free from regulation of law. 37 In Spain around 500...

Ngày tải lên: 16/01/2014, 22:20