methods to assess the activity of topicals against viruses

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Ngày tải lên: 07/08/2014, 20:23

... calculation of the equivalent of the degree of difficulty [25] as a measure of an Index of Discrimination (D) in order to identify those items from the TEMPS-A scale that best discriminate groups The ... between the different genotype groups to a high degree, no scale compiling these items showed high sensitivity and specificity with respect to the presence of the s allele Even the combination of the ... carried the ss genotype, 50 (36.23%) the ll and 69 (50%) sl genotype A total of 88 subjects (63.77%) carried the s allele while 50 subjects (36.23%) did not carry the s allele The frequency of the...

Ngày tải lên: 08/08/2014, 23:21

... the hospital along with feasibility to evaluate biomarkers of response to chemotherapy in these biopsies The correlation to response, if proven, would help clinicians to tailor chemotherapy to ... responders, similar to those reported in literature, are indirect evidence of the efficacy of the chemotherapy in these patients in eliminating the mitotic fraction It is intriguing to note that, as ... specimens using immunohistochemistry (IHC) c) Quantification of extent of change in these biomarkers of response to chemotherapy one day and 21 days after first cycle of chemotherapy http://www.wjso.com/content/7/1/35...

Ngày tải lên: 09/08/2014, 04:21

... peak to peak of the M-wave Motor distal latency (MDL) was obtained from the onset latency of the M-wave The latency between the anterior cells and the muscle was calculated according to the formula ... in the F-wave of the median nerve in CTS [17,18] Stoehr and colleagues found that the extent of the retrograde changes correlated with the degree of CTS severity [28] The sensory fibers of the ... cells and the muscle from the onset latency of MEPcr The latency from the anterior horn cells to the rootlet (CRL) was calculated by subtracting the onset latency of the MEPcv from the latency...

Ngày tải lên: 10/08/2014, 10:20

... instrument Phase 3: assessment of the reliability and validity of the new theory-based global instrument The objective of phase is to assess the reliability and validity of the new theory-based global ... assess the relationships between the constructs based on the proposed integrated model using path analysis Observation of the expected relationships will be further proof of the validity of the ... half of the participants, randomly selected, will be asked to complete the evaluation instrument both before and at the end of the CPD activity, and half of the participants will be asked to complete...

Ngày tải lên: 10/08/2014, 10:23

... 1% (-11% to +11%) and 9% (-4% to +21%) 6% (-31% to 33%) and 10% (-16% to 31) 31% (17% to -14%) and 19% (62% to 24%) 3% (17% to -14%) and 14% (-3% to +28%)1 13% (29% to -6%) and 36% (17% to 50%) ... be imprinted with the name of the patient and addressed directly to the primary care physician The statement will be faxed to the physician following the completion of the patient's coronary angiogram ... access to the data None of the local opinion leaders received any financial compensation for their participation in the study or endorsement of the evidence summaries Discussion We report the protocol...

Ngày tải lên: 11/08/2014, 05:22

... the SSRIs Furthermore, medication was superior to placebo in reducing the severity of the three symptom clusters of PTSD, as well as alleviating the symptoms of depression, and in improving the ... treatment of PTSD, the findings of prior topiramate studies suggest that this anticonvulsant may be promising in the management of patients with PTSD Aims of the Study 1) To compare the efficacy of topiramate ... prognosis [2] The development of treatments for PTSD is challenging due to the complexity of the symptoms and psychiatric comorbidities Psychotherapy and pharmacotherapy are the two main classes of PTSD...

Ngày tải lên: 11/08/2014, 17:20

... person within the area unit irrespective of where they live in that unit, the amount of time that they spend in the area, and their ability to travel within and beyond the boundary of the administrative ... measures of physical activity) so that the precise location where the physical activity is occurring is also captured [33,34] Given the high cost of the equipment, these data are often costly to collect, ... devices also enable investigators to track the mobility patterns of individuals through the environment to develop measures of their travel routes and activity spaces [32] These technologies have...

Ngày tải lên: 14/08/2014, 08:20

... mirror of the recording head and to close the flux loop from the head 1.2.2 Read and Write head The read sensor, the writer coil, together with the air bearing surface (ABS) are fabricated together ... relative to the position of linear stages A camera is positioned perpendicular to the plane of the disk media and guiding lines are drawn within the acquisition window to align the edge of the cartridge ... 2-1(a), the narrow peaks correspond to the harmonics of repeatable mechanical distortions (RRO) due to the rocking mode of the spindle system as well as disk surface distortions due to disk clamping...

Ngày tải lên: 26/11/2015, 12:14

... alpha-fetoprotein (AFP), found their way at an early stage into clinical laboratories Many others have followed in the meantime However, most of them are not tumor specific The use of changes of serum ... standard chemotherapies is usually high and that therefore the value of being able to escape useless treatments can be great The high cost of tests has to be considered too, yet the costs of drug treatment ... strategy of cancer drug therapy seems to be necessary, i.e the management may include, in cases of the detection of broad drug resistance, the omission of aggressive chemotherapy This would help to...

Ngày tải lên: 25/10/2012, 11:10

... In studies assessing the effect of ligand-binding on the quaternary structure of the receptors, the possibility that the antibodies could inhibit binding to the receptor also needs to be controlled ... expressed as the ratio of the distance ‘r’ separating the donor and the acceptor over the distance resulting in 50% of the maximal efficacy (R0) As indicated by the Forster equation, the efficiency of ¨ ... efficiency of transfer is determined both by the orientation of the energy transfer partners and by the distance between them [28] The fact that the efficiency of transfer varies with the 6th-power of the...

Ngày tải lên: 16/03/2014, 22:20

... malignant according to the histology To characterize the prosurvival activity of the peritoneal fluids against TRAIL, we assessed the cell viability in the presence or absence of peritoneal fluids ... anti-apoptotic activity of ascites Effect of ascites on drug sensitivity The sensitivity of CaOV3 cells to chemotherapeutic drugs was compared to that of TRAIL in the presence or absence of ascites ... sub-type of ovarian cancer In addition, the effect of ascites on primary tumor cells and most importantly the clinical significance of the prosurvival activity of ascites have not been assessed The...

Ngày tải lên: 20/06/2014, 07:20

... polymorphism, finding up to 32 polymorphic bands in all the trees evaluated On the other hand, the understanding of the genetic diversity presents in a species and the distribution of this variation ... 0.283) The 27.0% of the genetic diversity of this last group was detected among populations; however, this value was higher in Cordoba with 34.8% of total genetic diversity The proportion of genetic ... analyzed Previous to protein extraction, the samples (≈ 50 mg of cotyledon) were un-lipped with diethyl ether and acetone Cotyledon proteins were sequentially extracted according to the method described...

Ngày tải lên: 07/08/2014, 10:22

... in these multidimensional scales we used the unweighted scores In both cases, the higher the scores, the better the HRQoL, and vice versa (2) The Spanish version of the TOOL questionnaire The ... guided by the estimation of the utility function according to which a large number of patients is needed to maximise the precision and reduce the risk of measurement error To this end, in the present ... than 0.20 in the discrimination rate To assess the dimensionality of the questionnaire, an exploratory factorial analysis (extraction criterion of eigenvalue >1) was also conducted The Spearman...

Ngày tải lên: 09/08/2014, 01:21

... levels of MMP9 Implication of matrix metalloproteinases in proteolytic reactivity found in synovial fluids of RA patients To further assess the contribution of MMP-9 and other members of the MMP ... product of the chondrocytes, have predominant roles because they are rate limiting in the process of collagen degradation [27,28] The efficiency of these two inhibitors to block the enzymatic activity ... the net proteolytic activity resulting from the balance between the active forms of proteases and the naturally occurring protease inhibitors, to measure for the first time the diversity of the...

Ngày tải lên: 09/08/2014, 08:22

... care due to a lack of recognition by practitioners of ischemia or an underestimation of the severity of infections [10] Comprehensive assessments by health care professionals of risk factors are ... and their use of research evidence to inform practice [27,51-63] Similarly, a systematic review of 30 studies identified the lack of support from managers, and 'other staff' to be one of the ... diabetes 2) To determine the impact of the intervention on client, nurse and system outcomes 3) To understand the feasibility of influencing leadership behaviours through the intervention 4) To test...

Ngày tải lên: 11/08/2014, 05:21

... to inform them which arm of the trial they have been allocated to RA2 contacts the relevant support worker who will guide the relative through the intervention and instructs them to arrange the ... the participant’s views on the consequences of the illness, comprehension of the illness, knowledge of prognosis, the extent to which they attribute blame, knowledge of potential causes and their ... contributed to design of the intervention, recruits and assesses participants, and manages the process of randomisation; VP contributed to the design of the intervention and management of the project;...

Ngày tải lên: 11/08/2014, 15:22

... care due to a lack of recognition by practitioners of ischemia or an underestimation of the severity of infections [10] Comprehensive assessments by health care professionals of risk factors are ... and their use of research evidence to inform practice [27,51-63] Similarly, a systematic review of 30 studies identified the lack of support from managers, and 'other staff' to be one of the ... diabetes 2) To determine the impact of the intervention on client, nurse and system outcomes 3) To understand the feasibility of influencing leadership behaviours through the intervention 4) To test...

Ngày tải lên: 11/08/2014, 16:21

... (divergent selection from the top and bottom 5% of the population) to 0.83 (selection from the top 10% of the population) Sample sizes to detect significant = departures of Regr(u from its expectation ... absorption of ) fixed effects into u equations and factoring of residual variance from both sides of the equation, the coefficient matrix for u has: = = where A is the ratio of residual to sire ... of the u distribution a varied uniformly l l over the interval 0.7 to 0.95 AS2: 20 000 animals from the upper and lower 10% of the ui distribution a varied l uniformly over the interval 0.7 to...

Ngày tải lên: 14/08/2014, 19:22

... ―in terms of the appropriateness of the translator‘s intention to that of the author of the original, not of the appropriateness of the translator‘s intention to that of the evaluator‖ (1987:223) ... and professional activity but also to the field or topic of the text in its widest sense or ―area of operation‖ of the language activity, as well as details of the text production as far as these ... address the target audience of the translation because they are tight to the culture and the language community where they originate Therefore, to this type of translation, the function of the translation...

Ngày tải lên: 30/03/2015, 15:48