medical management of abdominal compartment syndrome
báo cáo khoa học: " Comparison of hyperthermia and adrenaline to enhance the intratumoral accumulation of cisplatin in a murin model of peritoneal carcinomatosis" potx
... should assess the effect of adrenaline; and that of groups and should assess the effect of the duration of IPC A 2- Page of hour HIPEC was impossible due to intolerance of the animals Atomic absorption ... France 2Department of Digestive Surgical Oncology, University Hospital of Dijon, France 3Department of Digestive Surgery, University Hospital of Besançon, France 4Department of Medical Oncology, ... the muscle of the abdominal wall We observed a ratio of to 17 in drug uptake between an abdominal muscle and a distant thoracic muscle This reflects the pharmacological advantage of IPC to obtain...
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Báo cáo y học: "New onset diabetes complicated by haemolysis and rhabdomyolysis: a case report and review of the literature" pot
... demonstrated in this case However, it is Page of (page number not for citation purposes) Journal of Medical Case Reports 2008, 2:159 http://www.jmedicalcasereports.com/content/2/1/159 A B C D ... complication of diabetic hyperosmolar nonketotic (HONK) state Journal of the Royal Society of Medicine 2006, 99(4):200 DKA: diabetic ketoacidosis; HONK: hyperosmolar nonketotic syndrome; G6PD: ... oximetry of 85% that did not alter with the concentration of inspired oxygen, and with discoloured urine and muscle weakness Despite the pulse oximetry reading, arterial blood gas showed a pO2 of 18.3...
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báo cáo hóa học:" Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)" pptx
... with microCT scanning of mice Author details Department of Pharmacology & Toxicology, University of Louisville, Louisville, KY 40292, USA 2Department of Chemistry, University of Louisville, Louisville, ... enhancement of cisplatin-induced cell death The goal of this study is to determine how sodium arsenite and hyperthermia modulate mechanisms of cisplatin resistance in vivo We developed murine models of ... were anesthetized with 3% isoflurane in an inhalation chamber and maintained on 1% isoflurane during surgery Incisions (~0.5 cm) were made on both sides of the lower abdominal wall allowing entry...
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Báo cáo hóa học: " Synthesis of Bio-Compatible SPION–based Aqueous Ferrofluids and Evaluation of RadioFrequency Power Loss for Magnetic Hyperthermia" docx
... precipitation of the oxide The rate of reaction was controlled by allowing one drop of ammonia per second to react with this solution until a pH of 10, to get a thick dark precipitate Five grams of citric ... a 1-cm cuvette at the photon energy of diode laser (670 nm) The simulation of the power loss spectrum of the sample was performed for applied field strength of 500Oe in the range 100–900 kHz Results ... nearly spherical Statistical analysis (Fig 2b) of the images revealed a normal distribution of particles with a mean size of 10 nm and a width of nm This is in fair agreement with the particle...
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Chapter 017. Fever and Hyperthermia (Part 1) docx
... define the 99th percentile for healthy individuals In light of these studies, an A.M temperature of >37.2°C (>98.9°F) or a P.M temperature of >37.7°C (>99.9°F) would define a fever The normal daily ... mechanisms of heat balance that function in the afebrile state When the hypothalamic set point is again reset downward (in response to either a reduction in the concentration of pyrogens or the use of ... elevation of body temperature that exceeds the normal daily variation and occurs in conjunction with an increase in the hypothalamic set point (e.g., from 37°C to 39°C) This shift of the set...
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Chapter 017. Fever and Hyperthermia (Part 2) docx
... often fatal The neuroleptic malignant syndrome occurs in the setting of neuroleptic agent use (antipsychotic phenothiazines, haloperidol, prochlorperazine, metoclopramide) or the withdrawal of ... sweating can dissipate ~600 kcal/h, requiring the production of >1 L of sweat Even in healthy individuals, dehydration or the use of common medications (e.g., over-the-counter antihistamines ... hyperthermia, but may be distinguished by the presence of diarrhea, tremor, and myoclonus rather than the lead-pipe rigidity of the neuroleptic malignant syndrome Thyrotoxicosis and pheochromocytoma can...
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Chapter 017. Fever and Hyperthermia (Part 3) pot
... (organum vasculosum of lamina terminalis)—networks of enlarged capillaries surrounding the hypothalamic regulatory centers Destruction of these organs reduces the ability of pyrogens to produce ... manifestation of disease in the absence of microbial infection For example, inflammatory processes, trauma, tissue necrosis, or antigen-antibody complexes can induce the production of IL-1, TNF, ... Elevation of the Hypothalamic Set Point by Cytokines During fever, levels of prostaglandin E2 (PGE2) are elevated in hypothalamic tissue and the third cerebral ventricle The concentrations of PGE...
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Chapter 017. Fever and Hyperthermia (Part 4) potx
... infections Measurement of circulating cytokines in patients with fever is of little use since levels of pyrogenic cytokines in the circulation often are below the detection limit of the assay or not ... the increasing use of anticytokines to reduce the activity of IL-1, IL-6, IL-12, and TNF, the effect of these agents on the febrile response must be considered The blocking of cytokine activity ... the production of fever is played by these cytokines produced in the brain itself? In experimental animals, the concentrations of cytokine required to cause fever are several orders of magnitude...
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Chapter 017. Fever and Hyperthermia (Part 5) pdf
... fever, hyper-IgD syndrome, familial cold-induced autoinflammatory syndrome, neonatal-onset multisystem autoinflammatory disease, Blau syndrome, Schnitzler syndrome, Muckle-Wells syndrome, and TNF ... to antipyretics Mechanisms of Antipyretic Agents The reduction of fever by lowering of the elevated hypothalamic set point is a direct function of reducing the level of PGE2 in the thermoregulatory ... with days of fever followed by a several-day afebrile period and then a relapse of days of fever In the Pel-Ebstein pattern, fever lasting 3–10 days is followed by afebrile periods of 3–10 days;...
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Chapter 017. Fever and Hyperthermia (Part 6) doc
... with cooling of blood may be performed.Malignant hyperthermia should be treated immediately with cessation of anesthesia and IV administration of dantrolene sodium The recommended dose of dantrolene ... malignant hyperthermia because of the likelihood of ventricular fibrillation in this syndrome Dantrolene at similar doses is indicated in the neuroleptic malignant syndrome and in drug-induced ... hyperthermia of the serotonin syndrome and thyrotoxicosis The neuroleptic malignant syndrome may also be treated with bromocriptine, levodopa, amantadine, or nifedipine or by induction of muscle...
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Chapter 020. Hypothermia and Frostbite (Part 1) potx
... factors often compound these problems by impeding adequate measures to prevent hypothermia Neonates have high rates of heat loss because of their increased surface-to-mass ratio and their lack of ... increases susceptibility to hypothermia Agenesis of the corpus callosum, or Shapiro syndrome, is one cause of episodic hypothermia, characterized by profuse perspiration followed by a rapid fall in ... Hunters, sailors, skiers, and climbers also are at great risk of exposure, whether it involves injury, changes in weather, or lack of preparedness Ethanol causes vasodilatation (which increases...
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Chapter 020. Hypothermia and Frostbite (Part 2) pot
... nervous system (CNS) lesion or one of the organic acidoses A markedly depressed level of consciousness in a patient with mild hypothermia should raise suspicion of an overdose or CNS dysfunction ... increased on increase diminishing of atrial and per level of ventricular 8°C autoreg drop in ulation conscio arrhythmias temperature usness; ; suggestive ; absence of impaire pupillar (J- y ECG wave) ... stimulation by hypothermia, there is progressive depression of all organ systems The timing of the appearance of these clinical manifestations varies widely (Table 20-2) Without knowing the core temperature,...
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Chapter 020. Hypothermia and Frostbite (Part 3) doc
... predicated on the type and severity of the precipitants of hypothermia There are no validated prognostic indicators for recovery from hypothermia A history of asphyxia with secondary cooling is ... hyperventilation in the setting of depressed CO2 production When the PCO2 decreases 10 mmHg at 28°C, it doubles the pH increase of 0.08 that occurs at 37°C The severity of anemia may be underestimated ... technique is preferable Insertion of a gastric tube prevents dilatation secondary to decreased bowel motility Indwelling bladder catheters facilitate monitoring of cold-induced diuresis Dehydration...
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Chapter 020. Hypothermia and Frostbite (Part 4) pot
... other forms of active core rewarming, it eliminates respiratory heat loss and adds 1°–2°C to the overall rewarming rate Crystalloids should be heated to 40°–42°C, but the quantity of heat provided ... with a countercurrent in-line heat exchanger Heated irrigation of the gastrointestinal tract or bladder transfers minimal heat because of the limited available surface area These methods should be ... hemithoraces Thoracostomy tubes should not be placed in the left chest of a spontaneously perfusing patient for purposes of rewarming Peritoneal lavage with the dialysate at 40°–45°C efficiently...
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Chapter 020. Hypothermia and Frostbite (Part 5) pdf
... sick euthyroid syndrome (Chap 335), historic clues or physical findings suggestive of hypothyroidism should be sought When myxedema is the cause of hypothermia, the relaxation phase of the Achilles ... rewarming The role of prophylaxis and treatment of ventricular arrhythmias is problematic Preexisting ventricular ectopy may be suppressed by hypothermia and reappear during rewarming None of the class ... administration of parenteral levothyroxine to euthyroid patients with hypothermia, however, is potentially hazardous Because laboratory results can be delayed and confounded by the presence of the sick...
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báo cáo khoa học: "Inflammatory myopathy and severe rhabdomyolysis induced by leuprolide acetate therapy for prostate cancer: a case report" pot
... of While cancer-associated myositis can ameliorate during cancer treatment [7], the treatment of cancer in our patient resulted in the development of clinical signs of myopathy On the basis of ... human immunodeficiency virus test was negative MRI of his legs showed edema of the proximal muscles, particularly of both adductors A biopsy of adductor muscle tissue was performed Histological ... immunohistochemical signs of autoimmune polymyositis or dermatomyositis The negative results of screening of our patient for these antibodies represent an additional argument against a diagnosis of autoimmune...
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báo cáo khoa học: " Hypothyroidism in a five-year-old boy with rhabdomyolysis and recent history of cardiac tamponade: a case report" pptx
... ultrasound Results of an anterior chest X-ray were normal Hematology tests on admission revealed a total leukocyte count of 6.83 K/UL, hemoglobin level of 12.5 g/dL and a platelet count of 310 K/μL ... ventricular collapse Delgado Hurtado et al Journal of Medical Case Reports 2011, 5:515 http://www.jmedicalcasereports.com/content/5/1/515 Page of Figure Thyroid scan with technetium showing a normal ... history of cardiac tamponade: a case report Journal of Medical Case Reports 2011 5:515 Consent Written informed consent was obtained from the patient’s legal guardian for publication of this...
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Báo cáo y học: " Near fatal posterior reversible encephalopathy syndrome complicating chronic liver failure and treated by induced hypothermia and dialysis: a case report" pps
... the first documented case of PRES associated with cirrhosis as well as the first report of induced hypothermia for the management PRES and the use of CVVHD for control of hyperammonemia in a cirrhotic ... ammonia levels by decreasing brain Page of (page number not for citation purposes) Journal of Medical Case Reports 2009, 3:6623 http://jmedicalcasereports.com/jmedicalcasereports/article/view/3/3/6623 ... loss of cerebral auto-regulation resulting in increased cerebral blood flow and vasogenic edema [7–10] Using magnetic resonance Page of (page number not for citation purposes) Journal of Medical...
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Báo cáo y học: "Hypothermia and neurologic outcome in patients following cardiac arrest: should we be hot to cool off our patients" pot
... summarizes some of the features of the two recent studies that examined the neuroprotective advantage of hypothermia in treatment of cardiac arrest ICU, intensive care unit; ROSC, restoration of spontaneous ... delayed hypothermia In a rat model, delays of 15 and 30 preserved the beneficial effect of hypothermia, but with delays of 45 there was no attenuation of infarct volume [12] In dogs, delaying hypothermia ... aspects were different (such as the time of initiation of hypothermia [in the field versus hospital] and duration of hypothermia [12 versus 24 hours]) Critics of those studies have expressed concerns...
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