... recent data on cytokine distribution in CFS/ME patients point towards an increase in pro-inflammatory cytokines suggesting the presence of an underlying viral prevalence in these patients [17,18] ... element DNA binding complex pathway, therefore changes in VNs such as elevations in VPACR2 may suggest an increase in IL-10 [45] Further, an increase in TNF-a and IFN-g suggests an inability of ... (Th)1, Th2 and Th17 cytokine expressions were investigated using the cytometric bead array kit (BD Pharmingen, San Diego, CA) [25] for determining levels of interleukin (IL)-2, IL-4, IL-6, IL10,...
Ngày tải lên: 18/06/2014, 19:20
... recent data on cytokine distribution in CFS/ME patients point towards an increase in pro-inflammatory cytokines suggesting the presence of an underlying viral prevalence in these patients [17,18] ... element DNA binding complex pathway, therefore changes in VNs such as elevations in VPACR2 may suggest an increase in IL-10 [45] Further, an increase in TNF-a and IFN-g suggests an inability of ... (Th)1, Th2 and Th17 cytokine expressions were investigated using the cytometric bead array kit (BD Pharmingen, San Diego, CA) [25] for determining levels of interleukin (IL)-2, IL-4, IL-6, IL10,...
Ngày tải lên: 20/06/2014, 03:20
Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"
... Vainchenker W, Wendling F Prominent role of TGF-beta in thrombopoietin-induced myelofibrosis in mice Blood 2002;100:3495-503 32 Erusalimsky JD, Franklin R and Hong Y Is the platelet lowering activity ... the other, is in accordance with some previous results [13,19] This lack also suggests that interactions are rather complex or slow; thus, in samples obtained at a single time point it might not ... advocated as a protein susceptible to reductions during anagrelide treatment for MPD [30] We can not corroborate those findings here, despite using the same assay as those investigators At this...
Ngày tải lên: 03/11/2012, 10:52
Tài liệu Deteriorating Access to Women’s Health Services in Texas: Potential Effects of the Women’s Health Program Affiliate Rule doc
... excluded from WHP, the remaining non-PPFA clinics would have to absorb a massive increase in WHP patients in order to maintain the overall 2011 caseload level Non-PPFA clinics in Bexar and Dallas Counties ... Effects of Reductions in Family Planning Funds As noted earlier, the planned changes in the WHP follow on major reductions in funding for family planning services in Texas beginning in 2011.46 It was ... women) in need of publicly-funded family planning services were served at publicly funded clinics and Title X clinics in Texas in 2008, which averted 98,700 unintended pregnancies, resulting in a...
Ngày tải lên: 13/02/2014, 06:20
Tài liệu Báo cáo khoa học: Critical roles of Asp40 at the haem proximal side of haem-regulated phosphodiesterase from Escherichia coli in redox potential, auto-oxidation and catalytic control doc
... black dotted and cyan broken lines, respectively The figure was obtained using PYMOL [20] characteristics, including optical absorption spectra, cyanide binding, redox potential and auto-oxidation ... structure in terms of cyanide binding in the Fe(III) complex Redox potentials Fig Soret and visible optical absorption spectra of Fe(III) (solid line), Fe(II) (broken line) and Fe(II)-CO (dotted line) ... J.D & Kang, C (2004) Insights into signal transduction involving PAS domain oxygen-sensing heme proteins from the X-ray crystal structure of Escherichia coli DOS heme domain (Ec DOSH) Biochemistry...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis pot
... is increased in chronic- vitamin A deficiency when compared to control rats Using Western blot analysis it was also found that p53 protein was increased and c-Jun protein was decreased in liver chronic- vitamin ... explain in part the decreased expression of c-Jun found in chronic1 9 vitamin A-deficient rats The molecular mechanism that explains the decrease in C-H-Ras expression found in chronic- vitamin A ... controls, while in acute hypervitaminosis the binding was significantly higher These changes in the RAR–DNA binding is not due to different levels of the retinoic acid receptor induced by the treatment,...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Supramolecular calsequestrin complex Protein–protein interactions in chronic low-frequency stimulated muscle, postnatal development and ageing pot
... the CSQ-binding element JUN, show decreased protein–protein interactions during fiber type shifting and the ageing process Reduced protein coupling between the major elements regulating Ca2+homeostasis ... changes in protein interactions between other SR Ca2+-regulatory proteins might also be involved in triggering impaired triadic signal transduction resulting in a progressive functional decline of ... heterogeneous protein–protein interactions Slow CSQ might be involved in a more indirect type of physiological coupling process in transformed fibers, while fast CSQ appears to be a directly interacting endogenous...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo Y học: Role of critical charged residues in reduction potential modulation of ferredoxin-NADP+ reductase Differential stabilization of FAD redox forms doc
... stabilizing the transient semiquinone, destabilizing the flavin hydroquinone complex and therefore in uencing the FAD reduction potential, support the original hypothesis of its role in proton ... respectively, suggesting that the K75 side-chain is somehow in uencing the FAD reduction potential within the protein environment FNR structure shows that K75 side-chain is not making any contact ... one-electron potentials This also indicates that, in E301A FNR, the H-bond network connecting E139 and N5 of the isoalloxazine does not substitute for E301 in modulating the flavin potential [18],...
Ngày tải lên: 08/03/2014, 23:20
EDUCATING TO IMPROVE POPULATION HEALTH OUTCOMES IN CHRONIC DISEASE ppt
... This domain includes: core clinical skills, applying knowledge of chronic conditions to clinical decision-making, physical examination skills, investigations and the rational use of medicine Note: ... nutrition etc Smoking Individual – Brief interventions in each consultation Community – Smoke free zones in public buildings • Conducting education to school kids about smoking • Running smoking education ... multidisciplinary teamwork, maintaining medical records; confidentiality; ethics in managing chronic disease; duty of care; professional standards, self-care, disciplinary scope of practice Clinical...
Ngày tải lên: 14/03/2014, 20:20
Anterior Knee Pain and Patellar Instability doc
... patellae have medial instability If someone performs a routine lateral release in a case of medial instability, he will end up vii viii Foreword having to repair the lateral retinaculum in order to ... worsening of clinical e We define the term “isolated symptomatic PFM” as anterior knee pain or patellar instability, or both, with abnormalities of patellar tracking during physical examination ... when patellar instability is going to be operated on, it is extremely important that the surgeon carefully controls in what direction the instability takes place All instability is not in lateral...
Ngày tải lên: 29/03/2014, 17:20
Anterior Knee Pain and Patellar Instability ppt
... patellae have medial instability If someone performs a routine lateral release in a case of medial instability, he will end up vii viii Foreword having to repair the lateral retinaculum in order to ... worsening of clinical e We define the term “isolated symptomatic PFM” as anterior knee pain or patellar instability, or both, with abnormalities of patellar tracking during physical examination ... when patellar instability is going to be operated on, it is extremely important that the surgeon carefully controls in what direction the instability takes place All instability is not in lateral...
Ngày tải lên: 29/03/2014, 17:20
Báo cáo hóa học: " Immune and hemorheological changes in Chronic Fatigue Syndrome" pdf
... severity of chronic fatigue syndrome Clin Infect Dis 1994, 18(Suppl 1):157-159 Maher KJ, Klimas NG, Fletcher MA: Chronic fatigue syndrome is associated with diminished intracellular perforin Clin Exp ... Belch JJF: Increased neutrophil apoptosis in chronic fatigue syndrome J Clin Pathol 2004, 57:891-893 Streeten DHP, Bell DS: Circulating blood volume in Chronic Fatigue Syndrome J Chronic Fatigue ... be an indicator of elevations in apoptotic neutrophils This potentially increases the life of bacteria and other pathogens in the body as they are not efficiently lysed owing to limited intracellular...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells" pot
... Becton-Dickinson, San Jose, CA) for 20 minutes, then treated with fixing and permeabilizing reagents (Fix&Perm kit, Caltag, Burlingame, CA) according to the manufacturer’s instructions, and finally stained ... following National Cancer Institute-Working Group guidelines [16] The concordance index (c index) was used to determine the predictive ability of ZAP-70 positivity in a TTT model Briefly, the c index ... expressing ZAP-70 according to T/B Ratiomethod (73), or expressing ZAP-70 according to either ISO- or Tmethods (30) Institution, in which ZAP-70 staining and analyses were performed utilizing a...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo sinh học: " Serum levels of preS antigen (HBpreSAg) in chronic hepatitis B virus infected patients" potx
... fusion during entry [20] Since preS mainly exist in the DNAcontaining Dane HBV particles, detection of HBpreSAg present in serum of HBV patients may have a clinical value in management of HBV infection ... recombinant S proteins was used to plot a standard curve The amount of HBsAg present in serum was determined according to the amount of recombinant S protein The result shown in Fig 1B indicated ... shown) Since the amount of spheres viral particles containing HBsAg is much more than that of infectious Dane particles (infectious particles containing L-M-S antigens and viral DNA) containing full...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo sinh học: " HBx M130K and V131I (T-A) mutations in HBV genotype F during a follow-up study in chronic carriers" potx
... infection in 2–10% of adults and in approximately 90% of infected infants Approximately 10% of these chronic patients develop progressive liver damage including cirrhosis and Hepatocellular Carcinoma ... Persistent chronic hepatitis, Knodell index ≤ Photomicrograph of liver showing chronic hepatitis with minimal activity Hepatocytes showing regenerative features are seen, with minimal inflammation ... Kobayashi et al, has shown in their study a higher prevalence of the T-A mutations in chronic patients during the acute phase than in acute self limited HBV infection in patients infected with genotypes...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo hóa học: " Energy expenditure in chronic stroke patients playing Wii Sports: a pilot study" pot
... boxing without extensive instruction and training Problems with timing of hitting the ball limited participants from playing Wii tennis, most likely resulting from stroke-induced deficits in ... decreased to chair-sitting level After resting, the participants played Wii Sports tennis and boxing for 15 minutes each, in random order, with a 10-minute minimum intervening rest period, or until ... tennis and boxing at home Larger prospective studies are needed to determine the effectiveness and potential side-effects of Wii game play for maintaining and improving health in chronic stroke...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo hóa học: " Effects of a robot-assisted training of grasp and pronation/supination in chronic stroke: a pilot stud" pot
... was significant increase in the MS (Friedman p
Ngày tải lên: 19/06/2014, 08:20
Báo cáo hóa học: " A new electromechanical trainer for sensorimotor rehabilitation of paralysed fingers: A case series in chronic and acute stroke patients" pdf
... extension in healthy subjects [23] While passive movements caused some increase in activation, active training led to more prominent increases in fMRI activation, recruitment curves (TMS) and intracortical ... concave, forming a gutter to maximise the contact area between finger & roll Two smaller locking rollers, also concave, hold each finger against the larger finger roll Each pair of locking rollers ... axis of the finger roll, and an elastic spring pulls each pair of locking rollers towards the finger roller These can be lifted out of the way when first positioning the hand & fingers in the device...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: "Effects of intensive arm training with the rehabilitation robot ARMin II in chronic stroke patients: four single-cases" potx
... arm functions (+21 points) The FMA gains of patients and were +5 points (from 24 to 29 points) and +8 points (from 11 to 19 points) These findings were in line with other investigations about ... sequences, including coordinated interactions between wrist, elbow and shoulder joints This seems to be an important feature since most everyday activities are composed of inter-joint coordination ARMin ... first pilot study with three chronic stroke patients showed significant improvements in motor functions with intensive training using the first prototype ARMin I Since ARMin I provided therapy only...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: "An explorative, cross-sectional study into abnormal muscular coupling during reach in chronic stroke patients" pdf
... This resulted in upward and outward reaching movements using both shoulder and elbow rotations, resembling for instance reaching for a cup in a drawer Two sets of multi-joint reaching movements ... result in more pronounced increases in SREvalues with resistance in chronic stroke patients than in healthy persons, especially regarding shoulder elevators and elbow flexors However, the findings ... = 0.094) Again, these results not point to an abnormal coupling between AD and elbow flexors, since an increase in AD activity was accompanied by a less than proportional increase in BIC and BRA...
Ngày tải lên: 19/06/2014, 08:20