mathematical modeling of the loss of telomere sequences

... calculate the angles of the triangle Knowing these angles, we further calculated changes in the location of the right knee that would result from hypothetical reductions in the length of either the ... knee position affected both the altitude of the knee from the table top, and its Y axis position along the length of the table We also calculated the hypothetical effect of one hip being drawn up ... to bring the infant's feet to his or her buttocks In neither of these papers we see any mention of assessing the Y axis location of the knee, as chiropractors performing their version of Allis...

Ngày tải lên: 13/08/2014, 14:20

... a mathematical model of the cell cycle and its circadian control The following question is addressed: Can one sustain, on the basis of mathematical models, that for cancer cells, the loss of ... of operating cells The central idea of the mathematical model is that the regulatory nature of osteocytes is the basis of the cyclic behavior associated with the system (remodeling process) as ... hypothesis about the existence of the pool of nonspecific electron acceptors and donors The results of 3D simulation visually display the role of spatial organization of the system in forming the...

Ngày tải lên: 27/06/2014, 10:20

... in this thesis is also presented in this chapter 2.1 Theories of mathematical modeling Employing mathematical modeling in the design of batteries has a long history In the late 1950’ the macroscopic ... In this thesis, only irreversible capacity fade is taken into account 1.2 MATHEMATICAL MODELING OF LITHIUM-ION BATTERIES 1.2 Mathematical modeling of lithium-ion batteries Mathematical modeling ... review of the mathematical models developed for predicting the electrochemical and the thermal behavior of lithium-ion batteries as well as the existing thermal management designs 12 1.5 OUTLINE OF...

Ngày tải lên: 09/09/2015, 08:12

... declare that the thesis is my original work and it has been written by me in its entirety I have duly acknowledged all the sources of information which have been used in the thesis This thesis has...

Ngày tải lên: 09/09/2015, 17:54

... cytoplasm of the cell contains a vast array of other proteins and structures which maintain the everyday activities of the cell In cell migration, the skeleton of the cell, known as the cytoskeleton, ... researchers realize the need for quantitative analysis of both the mechanical as well as the biochemical aspects at multiple scales The objective of this thesis is therefore to use mathematical and ... prevent the elongation of actin filaments by blocking the addition of new monomers at the barbed end [264] Gelsolin, on the other hand, can sever actin filaments, therefore regulating the length of...

Ngày tải lên: 09/09/2015, 18:51

... part of the oxidant parasitically reacts with the crossover fuel The fuel loss is the culprit behind the reduction of the open-circuit voltage, for example, the methanol-fed fuel cell have the theoretical ... experimental validation of a DLFC model (Chap 9) There are ten chapters in this thesis The rst chapter motivates the aim of the work along with an overview of the contributions of the thesis Chapter provides ... and the codependency of these phenomena in the individual layers of the DLFC Owing to the typical size of the DLFC (see Fig 1.2), it is di cult to measure these internal quantities within the...

Ngày tải lên: 10/09/2015, 08:26

... that the NTHi form biofilms on the respiratory mucosa of humans and other mammals and it has been hypothesized that this contributes to the chronicity of these infections [1,2] They are the most ... compared to the Rd KW20 strain The average total length of non-matching sequences between the 12 clinical strains and Rd was 321 kb, approximately 18% of the genome The quantity of non-matching sequences ... estimated by the A histogram of gene the expected number of genes of 13 H influenzae A histogram of gene clusters observed in exactly N of 13 H influenzae strains compared to the expected number of genes...

Ngày tải lên: 14/08/2014, 07:21

... many years Rather the ideas of kinetic theory found their way into other fields, such as radiative transfer, the theory of ionized gases, the theory of neutron transport and the study of quantum ... extension of the molecular hypothesis is the theory (called the kinetic theory of heat) that the molecules move more or less rapidly, the hotter or colder the body of which they form part; and that the ... molecules These structures are therefore not of immediate concern in the kinetic theory of gases; they determine the exterior fields of force, which form the outworks of the molecule, and it is only the...

Ngày tải lên: 13/02/2014, 23:20

... illustrates the overall saddle shape of the dimeric structure and the key heparin-binding residues in the N-terminal domain held coordinately by the two subunits on the top of the hollow (Fig 1A) The ... established Of two possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL ... peak of wild-type LPL The LPL in the eluate was detected by Western blot with LPL polyclonal antibody 7640 The fraction number of the high-affinity peak was the same for the wild type and the WW...

Ngày tải lên: 21/02/2014, 15:20

... induced against the linear isoform of the HNE peptide Although the binding pattern may be somewhat blurred by these antibodies and by the polyclonal nature of the sera, the importance of residues ... crossreactivity with the intact protein (Fig 8B,F) For the binding of the sera to the HNE peptide, the importance of the Cys residues was relatively low, in comparison to the binding with the mAbs BH216, ... In some of the conformers a hydrogen bond was predicted between the carbonyl atom of the Cys386 residue and the main chain nitrogen atom of residue Ile390 The total contact surface of the epitope...

Ngày tải lên: 08/03/2014, 08:20

... added to the cells, in order to assess the influence of these added substrates on the rate of urea synthesis Model Written in Mathematica, the basic model simulates the timedependent flux of metabolites ... Simulating the effect of the addition of mM unlabelled arginine on the distribution of radioactivity in cytoplasmic intermediates of the urea cycle As the pattern of distribution of radioactivity ... equations using these matrices Results Simulation in the absence of added metabolites The Mathematica program stores the numerical solution of the differential equations as a set of interpolating...

Ngày tải lên: 08/03/2014, 08:20

... overloading of the SRP pathway The re-routing of (G-10L)prePhoE to the Sec translocon via the SRP instead of the SecB pathway could be explained by the increased hydrophobicity of the hydrophobic core of ... analysis of signal sequences revealed the common occurrence of helix-breaking residues within the hydrophobic core [28], suggesting that the disruption of the a-helix is a common feature of signal sequences ... prePhoE in the case of the TF crosslinked complexes These amounts were set to 100%, and the relative cross-linking efficiencies of the other prePhoE forms to TF and P48 are shown of SecA The  40-kDa...

Ngày tải lên: 08/03/2014, 09:20

... The Mathematical Foundation of Informatics This page intentionally left blank The Mathematical Mathematicalal a al Foundation of Informatics I Proceedings of the Conference 25 ... where P is the class of all polynominals, then L is not acceptable by any Petri net Proof The proof is analogous to the one of corollary By the Corollaries and 2, we can show a lot of rather simple ... recognizing L The cardinal of the set of subsets (of the set of states) is 2ca'd(d(L)) This number bounds the number of V, ( n 1) Theorem Let L be a rational language L is a n w-code i f and only if there...

Ngày tải lên: 15/03/2014, 12:20

... re-entry of protons into the matrix, bypassing F0 F1-ATPsynthase [6] The dotted line shows the result of the modeling after estimation of the unknown parameters The con- Modeling of ANT ditions of the ... is from the matrix to the intramembrane space The integer coefcients of the right-hand side of the second equation of the system (3) were chosen on the basis of the knowledge of number of charges ... also seen in Fig 3, the calculated values of the protonmotive force (PMF) in the presence of nigericin are higher than those in the absence of the ionophore The calibration of the safranine O uorescence...

Ngày tải lên: 16/03/2014, 00:20

... diffusion of silicon atoms from the surface to the catalyst/NW interface Here, h is the height of the NW and O is the atomic volume of a silicon atom in a silicon lattice, the factor is the ratio of the ... equations describing the growth of NWs The second two MC experiments reproduce a fragment of a Fig The MC simulations of the kinetics for spreading of the mobile atoms across the surface in a two-component ... but by the direct adsorption of molecules to the vacant sites located in the very peripheral region of a catalyst particle The width of the region gradually decreases with the increase in the input...

Ngày tải lên: 16/03/2014, 15:18

... layer, problems of modeling of avalanching, etc In spite of the fact that the foundations of the theory have been laid even at the beginning of the development of continuum mechanics in the classical ... features of the deformation process are obtained The static and kinematic theorems of the limit equilibrium theory are extended to the case of heteromodular materials On the basis of the finite ... Mathematical Modeling, System Analysis and Automation’’ of the Presidium of RAS, the Interdisciplinary Integration Project no 40 of the Siberian Branch of RAS, the grant no MK– 982.2004.1 of the President...

Ngày tải lên: 16/03/2014, 22:20

Ngày tải lên: 17/03/2014, 14:03

Ngày tải lên: 17/03/2014, 14:36

... on the basis of the Nambu equations of motion, and anti-rigid if the correction terms act to enhance the curvature of the world sheet Numerical simulation of the collapse of a circular loop of ... ingredients of cosmological models solely because of the role of the Higgs mechanism in electroweak unification Most accounts of the formation of cosmic strings offer only a heuristic explanation of the ... assume their false vacuum values (n and respectively) on the axis of symmetry, and fall off exponentially with the cylindrical radius ρ The centre of the string is, therefore, the set of points...

Ngày tải lên: 17/03/2014, 14:48