management of gastric cancer

... imaging findings of gastric wall invasion included case of T1, of T2 (Figure 7), and 11 of T3 (Figure 8) Pathologic results of resected specimens included cases of pT1, of pT2, and 12 of pT3 Differentiation ... layers of the gastric wall and also MRI of gastric carcinoma could enable accurate diagnosis of location, gross appearance, degree of gastric wall invasion of the tumors and delineation of regional ... often are used for better assessment of the stage of the disease Positron emission tomography (PET) has been evaluated recently in the staging of gastric carcinoma 38 Management of Gastric Cancer...

Ngày tải lên: 28/06/2014, 05:20

... 2008.11,12  management of cervical cancer 1.2 remit of the guideline This guideline will cover presentation, referral, diagnosis, staging and treatment of cervical cancer The management of small ... assessment of results of the investigations and discussion with the patient 12 MANAGEMENT OF COMPLICATIONS IN ADVANCED DISEASE The management of extrinsic malignant ureteric obstruction is a balance of ... counselling 35 management of cervical cancer 12.3 THROMBOTIC and bleeding problems Patients with advanced cervical cancer are at risk of both thrombosis and haemorrhage as a consequence of their cancer...

Ngày tải lên: 14/02/2014, 22:20

... range of aspects of breast cancer treatment 1.4 Statement of intent This guideline is not intended to be construed or to serve as a standard of care Standards of care are determined on the basis of ... treatment of breast cancer Clinical practice guidelines for the care and treatment of breast cancer: 14 The role of hormone replacement therapy in women with a previous diagnosis of breast cancer ... PJ.Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) as a measure of psychosocial function in Breast cancer patients Eur J Cancer 1998;34(4):510-7...

Ngày tải lên: 08/03/2014, 14:20

... selected T1 rectal cancers Level of Evidence: Class II; Grade of Recommendation: B Local excision of rectal cancer is an appropriate alternative therapy for selected cases of rectal cancer with a ... assessment of the size and degree of fixation of mid and low rectal tumors Although digital assessment of the extent of local disease may be imprecise, it provides a rough estimate of the local ... Campbell H, et al Accuracy of reporting of family history of colorectal cancer Gut 2004;53:291–5 Nicholls RJ, Mason AY, Morson BC, Dixon AK, Fry IK The clinical staging of rectal cancer Br J Surg 1982;69:...

Ngày tải lên: 15/03/2014, 01:20

... 13 Ovarian cancer: the recognition and initial management of ovarian cancer Figure 1.18 Stages of the National Cancer Peer Review Programme on gynaecology cancer teams (2004-2008) All cancer networks ... diagnosis of cancer Part of this initiative has led to the development of ‘Key messages for ovarian cancer for health professionals’1 which aim to raise awareness of signs and symptoms of the disease ... prior probability of undiagnosed ovarian cancer of 0.04% (Hamilton et al., 2009) 17 Ovarian cancer: the recognition and initial management of ovarian cancer Box 2.1 Definitions of terms used in...

Ngày tải lên: 22/03/2014, 16:21

... breast cancer Management of special problems in breast cancer Figure 13 Paget’s disease of the nipple-areola complex Figure 14 Cancer of the male breast: diagnosis 37 38 Guidelines for management of ... breast cancer This chapter gives guidelines on management of special problems in breast cancer (Figures 11–16) Figure 11 Phyllodes tumour of the breast 36 Guidelines for management of breast cancer ... score ≥ 75% of the tumour is composed of tubules score 10%–75% of the tumour is composed of tubules score < 10% of the tumour is composed of tubules Pathological handling of breast cancer excision...

Ngày tải lên: 28/03/2014, 23:20

... thyroid cancer, (69%) were due to second malignancies (three breast cancer case, prostate cancer case, case of sigmoid colon cancer, case of liver cancer, case of glioblastoma multiform, case of pancreatic ... survival of thyroid cancer by age group, excluding MPTC (1978-2001) 1,0 8-44 years of age 45-54 years of age 55-64 years of age 65-74 years of age Cancer- specific Survival 0,8 75-95 years of age ... corresponded to medullary and papillary cancers of the thyroid Anaplastic cancer and Hỹrthle cells occurred at older ages Of the total of thyroid cancers, 78.3% of the cases were females and 21.7%...

Ngày tải lên: 30/03/2014, 22:20

... Post HOC Scheffe, p > 0.05) GC, gastric cancer; EGC, early gastric cancer; AGC, advanced gastric cancer Page of 11 (page number not for citation purposes) Journal of Translational Medicine 2009, ... (cut-off value of 5.5 ng/ml), and 71% and 67% (cut-off value of ng/ml) The sensitivity and specificity of serum CEA levels for the diagnosis of high-risk lesions was 39% and 76% (cut-off value of ... of our study [20,21] However, the sensitivity and specificity of serum HMGB1 was about 71% and 67% (cut-off value of ng/ml) for the detection of cancer (EGC), and 70% and 64% (cut-off value of...

Ngày tải lên: 18/06/2014, 15:20

... the interface of tumor nest and stroma is the main location of infiltrating macrophages in gastric cancer, and phagocytosis of cancer cells by macrophage, indicating the coexistence of M1 and M2 ... observable step of cancer progression Cancer invasion occurs in a particular context of tissue microenvironment which is under constant evolution largely due to the interactions of cancer cells ... of cancer molecules, while the clinical studies focused on the “spatial evolution” of cancer tissues The underlying theory behind these studies is to focus on cancer itself A major drawback of...

Ngày tải lên: 18/06/2014, 16:20

... evaluation of HIPEC In recent years, increasing number of animal models of PC have been intensively studied, including nude mouse model of gastric cancer PC constructed by implanting human gastric cancer ... by the Animal Welfare Committee of the Center Construction of rabbit model of VX2 gastric carcinoma with PC Rabbit VX2 carcinoma was used to establish gastric cancer with PC in this study The ... animal model of PC from gastric cancer for experimental studies to test extensive CRS and HIPEC In our previous study [19], we have established a stable rabbit model of gastric cancer with PC...

Ngày tải lên: 18/06/2014, 19:20

... augments anti -cancer immunity in a mouse model of gastric cancer Journal of Translational Medicine 2011 9:140 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient ... increase of Tregs does not necessarily affect the anticancer effect of the treatment It remains to be determined whether late appearance of Tregs actually has an impact on the therapeutic efficacy of ... four mimicry epitopes for gastric cancer Cancer Biol Ther 2005, 4:308-312 25 Nockel J, van den Engel NK, Winter H, Hatz RA, Zimmermann W, Kammerer R: Characterization of gastric adenocarcinoma cell...

Ngày tải lên: 18/06/2014, 22:20

... evaluation of HIPEC In recent years, increasing number of animal models of PC have been intensively studied, including nude mouse model of gastric cancer PC constructed by implanting human gastric cancer ... by the Animal Welfare Committee of the Center Construction of rabbit model of VX2 gastric carcinoma with PC Rabbit VX2 carcinoma was used to establish gastric cancer with PC in this study The ... animal model of PC from gastric cancer for experimental studies to test extensive CRS and HIPEC In our previous study [19], we have established a stable rabbit model of gastric cancer with PC...

Ngày tải lên: 20/06/2014, 03:20

... irradiation sensitizer in gastric cancer therapy Guidelines of the NCCN on gastric cancer Figure Quantification of mRNA expression of different genes Analysis of mRNA expression of COX-2, VEGF and EGFR ... and EGFR genes in gastric cancer cells, which was mainly due to the decrease in expression of NF-B via inhibited b-ARs Discussion Gastric cancer is one of the major causes of cancer mortalities ... patients with a high risk of recurrence in gastric cancer Investigation of the specific mechanisms of NF-B activation by radiation is currently a rapidly expanding field of research It has been...

Ngày tải lên: 09/08/2014, 09:20

... the SPSS software package (SPSS Inc, Chicago, USA) A value of P < 0.05 was considered significant Results Down-regulation of COX-2 inhibited the growth and tumorigenecity of gastric cancer cells ... might inhibit the malignant growth of SGC7901 cells in vivo Down-regulation of COX-2 inhibited angiogenesis of gastric cancer cells As shown in Figure 3, the number of endothelial cells within the ... (right) Yao et al Journal of Experimental & Clinical Cancer Research 2011, 30:13 http://www.jeccr.com/content/30/1/13 Page of of COX-2 was frequently found in gastric cancer, in which COX-2 expression...

Ngày tải lên: 10/08/2014, 10:21

... retention in cancer cells The results of FCM showed that down-regulation of miR- Figure Effects of a miR-27a on expression of cyclin D1, P-gp, p21 and p27 in gastric cancer cells The mRNA level of the ... time results of MTT assay and soft agar assay revealed that down-regulation of miR-27a inhibited cell growth of gastric cancer cells in vitro, which was consistent with the data of nude mice ... of miR-27a might inhibit the growth of MKN45 cells in vitro and in vivo Down-regulation of miR-27a might reverse drug resistance of gastric cancer cells As shown in Table 1, the IC50 values of...

Ngày tải lên: 10/08/2014, 10:21

... Yamamoto H: Participation of c-met in the progression of human gastric cancers: anti-c-met oligonucleotides inhibit proliferation or invasiveness of gastric cancer cells Cancer Gene Ther 1996, 3:393-404 ... promotes apoptosis of gastric cancer cells Journal of Experimental & Clinical Cancer Research 2011 30:67 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online ... therapeutic target for this type of cancer [3] The aim of this study was to evaluate the effects of recombinant immunotoxin anti-c-Met/PE38KDEL on proliferation and apoptosis of GC cells and explore the...

Ngày tải lên: 10/08/2014, 10:21

... or kill early gastric cancer cells is very key for early diagnosis and therapy of patients with gastric cancer Up to date, looking for biomarkers closely associated with gastric cancer is still ... associated with early gastric cancer were identified [5,6], no one gene can be confirmed to be specific biomarker of gastric cancer Therefore, in order to recognize early gastric cancer cells, we ... target for most gastric cancer, if as-prepared nanoprobes may recognize 64% patients with early gastric cancer, it will be very useful for diagnosis and therapy of clinical gastric cancer patients...

Ngày tải lên: 11/08/2014, 00:23

... karyotyping of seventeen gastric cancer cell lines 7.1 Gastric cancer spectral karyotypes 7.2 148 Recurrent patterns of translocations Multimodality whole genome characterization of gastric cancer ... Table of contents Contents TITLE PAGE i ACKNOWLEDGEMENTS ii TABLE OF CONTENT iv SUMMARY vii LIST OF TABLES xi LIST OF FIGURES xiii LIST OF ABBREVIATIONS xx REVIEW OF THE LITERATURE Gastric cancer ... in surgery: gastric cancer Curr Probl Surg 43, 566-670 (2006) 22 Japanese Gastric Cancer Association Japanese Classification of Gastric Carcinoma - 2nd English Edition - Gastric Cancer 1, 10-24...

Ngày tải lên: 14/09/2015, 08:38

... the cancer biology through systematic analysis of whole genomes and transcriptomes 1.2 Gastric Cancer Gastric cancer is a leading cause of cancer mortality worldwide, surpassed only by lung cancer ... treatment of gastric cancer is that very few of the currently utilized classification schemes are strong predictors of clinical behavior Traditional classifications of gastric cancer on the basis of ... members of Asia-Pacific Gastric Cancer Genomics Consortium (Prof Hiroyuki Aburatani, University of Tokyo, Japan; Prof David Bowtell, Peter MacCallum Cancer Centre, Australia; Assoc Prof Suet...

Ngày tải lên: 15/09/2015, 17:09