magnitude and relative significance of pathways

... and stand behind the offering that the customer will buy and use.” (Aaker, 2004, 6) The concept of a brand goes beyond the name or mark The brand identifies and differentiates the offerings of ... strong brand essential for the success of the company Brand awareness, brand credibility and brand loyalty are key factors in generating competitive advantage and growth Brand recognition and a ... Journal of Product and Brand Management, 21, 6, 439-451 Hoeffler, S and Keller, K L (2003) The marketing advantages of strong brands, Journal of Brand Management, 10, 6, 421-445 Huang,R and Sarigöllü,

Ngày tải lên: 19/12/2016, 12:18

... by deposition of several kilometres of Palaeozoic and Mesozoic sedimentary and volcanic strata It is, therefore, worthwhile to consider the mechanisms and timing of exhumation of the exposed Neoproterozoic–Early ... terms of the age and tectonic significance of its basement and the history of its exhumation In this research we used U-Pb Laser Inductively Coupled Mass Spectrometry (LA-ICP-MS) age data and focused ... structure of the Sanandaj-Sirjan Zone was imposed during the collision of Arabia and Eurasia and the subsequent southward propagation of the fold-thrust belt (Alavi 1994), with the Sanandaj-Sirjan

Ngày tải lên: 13/01/2020, 19:24

... naru2000us@yahoo.com Faculty of? ?Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001, India Full list of author information is available at the end of the article Discovery of drug is a slow, ... binding pocket Compounds Ax8 and Ax10 having significant antimicrobial and anticancer activities may be selected as lead compounds for the development of novel antimicrobial and anticancer agent, respectively ... class of antimicrobial drugs [2] Tumor is a severe health issue and 2nd leading/most reason for mortality in the globe It is caused by deregulation of the cell cycle which results in failure of

Ngày tải lên: 29/05/2020, 13:51

... Foundation of Hubei Province All funding bodies contributed equally in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript Availability of data and ... domains: selection of participants, comparability of study groups, and the ascertainment of outcomes of interest We considered studies with scores more than as high-quality studies, and those with ... characteristics of the included studies are shown in Table Among these studies, a total of 613 patients were Page of 10 included, with a maximum sample size of 153 patients and a minimum sample size of 54

Ngày tải lên: 03/07/2020, 01:14

... family, and serves as a negative regulator of the immune system by inhibiting the function of T-cells in local tissues [2, 3] PD-L1 (also known as CD275 and B7-H1) is one of the PD-1 ligands and ... parameters of the studies included in this meta-analysis Kim et al BMC Cancer (2017) 17:690 Page of 11 Kim et al BMC Cancer (2017) 17:690 England, Switzerland, Korea, and Saudi Arabia In of the studies, ... Ministry of Health & Welfare, Republic of Korea (1420080) and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future

Ngày tải lên: 06/08/2020, 04:16

... Foundation of China (No 81572874) The funding body was not involved in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript Availability of data and ... Page 12 of 13 selection, and figs CY, KZ and ZW provided clinical expertise and interpretation of data The report was drafted, revised, and approved by all investigators All authors read and approved ... conclusions of this article are included within the article Authors’ contributions CY and KZ contributed equally to this work CY, KZ, and BX were responsible for conception and design of the study CY and

Ngày tải lên: 06/08/2020, 04:31

... further evaluate the prognostic significance of mTOR and p-mTOR in detail, all of six included studies addressing on the relationship between mTOR/p-mTOR expression and OS of ESCC cases were stratified ... evaluate the prognostic and clinicopathological significance of mTOR/p-mTOR expression in ESCC Methods: Literature retrieval was conducted by searching PubMed, EMBASE and the Web of Science for full-text ... the feasibility and safety of esophagectomy but hardly benefited the prognosis of ESCC [4] The possible main reason may be the detectable regional and distant metastasis in most of the patients

Ngày tải lên: 20/09/2020, 18:47

... cut-off value was determined as the point yielding the greatest sum of sensitivity and specificity for prediction of outcome b, c Kaplan-Meier analysis of progression-free and overall survival of ... prognostic and predictive significance of LINE-1 hypomethylation in metastatic CRC patients who undergo treatment with FOLFOX The aim of the present study was therefore to determine whether the level of ... contribute to the development and progression of cancer, including CRC, by silencing the expression of tumor suppressor genes [5] On the other hand, genome-wide hypomethylation of tumor DNA induces genomic

Ngày tải lên: 20/09/2020, 18:56

... tomography of the chest and upper abdomen, and ultrasound of the neck Pulmonary and cardiac function tests were routinely performed to assess medical operability Recurrent laryngeal nerve palsy and ... model for outcomes of esophageal cancer patients also requires to be further investigated The purpose of this study was to evaluate the prognostic and predictive significance of tumor length in ... undergoing radical resection Jie Wu* and Qi-Xun Chen Abstract Background: The objective of this study was to investigate the prognostic and predictive significance of tumor length in patients with

Ngày tải lên: 21/09/2020, 01:38

... contributions ZG and DJ contributed equally to this work ZG, DJ, and JH participated in the conception and design of the study ZC and MW participated in article selection and data extraction and provided ... expertise ZG and DJ did the studies selection, data extraction, statistical analyses and the writing of report MW and ZC contributed to the literature search and figures ZG, DJ, and JH participated ... revision of the manuscript and interpretation of data All authors drafted and critically revised the manuscript and approved the final version Acknowledgments We thank the department of Breast

Ngày tải lên: 22/09/2020, 23:53

... University of Technology and Education make and the significance of error correction in English writing teaching To achieve the desired aims of the current study, I combined both qualitative and quantitative ... between errors and mistakes 1.4 Sources of errors 1.5 Error analysis Error correction and significance of error correction CHAPTER II : METHODS OF THE STUDY ... English major students at Hung Yen University of Technology and Education and the significance of correcting errors to English writing teaching” Aims of the study The study is aimed at investigating

Ngày tải lên: 23/09/2020, 22:13

... Digest of Statistics Directorate of Economics and Statistics Government of Jammu and Kashmir Pp- 152 Anonymous 2016-17b Digest of Statistics Directorate of Economics and Statistics Government of ... potential of the crop Yield and yield attributes of direct seeded basmati rice The data on yield attributes viz., number of plants/m2, number of panicles/m2, number of grains/panicle and test weight and ... weights of 9.41 and 9.14 % recorded at crop harvest stage under weedy check plots during kharif seasons of 2014 and 2015, respectively Economics Relative economics in terms of net returns and B

Ngày tải lên: 28/09/2020, 16:46

... Long-Term Study of 105 Patients with Cystic Fibrosis Ama Journal of Diseases of Children 1958, 96(1):6-15 14 [Anon]: Standardization of Spirometry - 1994 Update American Journal of Respiratory and Critical ... small number of patients, CRP levels of >60 mg/l were present in 20 of all 32 (= 63%) children with bacterial pneumonia and had a high diagnostic accuracy of 93.6% for diagnosis of pneumonia ... in serum at a cut-off value of 5429 ng/ml resulting in a sensitivity of 100% and a specificity of 96.8% Figure Soluble CD14 levels and bacterial pneumonia BALF (A) and soluble (B) sCD14 levels...

Ngày tải lên: 12/08/2014, 11:21

... genetic, and biochemical factors associated with the development and progression of OA at multiple sites (hand, knee, hip, and spine) Subjects between the ages of 50 and 80 years where randomly ... Osiris software (University of Geneva, Geneva, Switzerland) and were defined as areas of increased signal adjacent to the subcortical bone at the medial tibial, medial femoral, lateral tibial, and ... Knee pain, function, and stiffness assessments consisted of 5, 17, and questions each; therefore, the range for each of these is from to 45, to 153, and to 18, respectively Page of 12 In further...

Ngày tải lên: 12/08/2014, 15:22

... addition of GlcA and GlcNAc N-deacetylation and N-sulphation of GlcNAc units N-deacetylation and N-sulphation of GlcNAc units N-deacetylation and N-sulphation of GlcNAc units N-deacetylation and N-sulphation ... single acini of variable size and separation, cribriform and papillary patterns irregular masses of acini and fused epithelium, presence of clear cells almost complete loss of glandular lumen; ... addition of GlcA and GlcNAc Chain polymerization: alternate addition of GlcA and GlcNAc Chain polymerization: alternate addition of GlcA and GlcNAc Chain polymerization: alternate addition of GlcA and...

Ngày tải lên: 12/09/2015, 11:08

... intensity of bands after background subtraction and are relative to white (value 0) and black (value 256) The blots each show a single band for Akt and p-Akt at about 60 kDa and each show a double band ... inhibition of the Akt and Erk pathways inhibit the stimulatory actions of FSH and IGF on cultured bovine granulosa cells and LH on theca cells in vitro Furthermore, inhibition of the Akt and Erk pathways ... double band for Erk and p-Erk at about 44 and 42 kDa Experiment Effects of LH in combination with PD98059 and/ or LY294002 on cell number and secretion of androstenedione and progesterone from...

Ngày tải lên: 20/06/2014, 07:20

... et al.: Pathways to child and adolescent psychiatric clinics: a multilevel study of the significance of ethnicity and neighbourhood social characteristics on source of referral Child and Adolescent ... structure and the ethnic composition of Sweden, with her relatively new immigrant population, differ significantly from those of the USA Nevertheless similar patterns of discrimination and of inequalities ... decade of the 20th and the first years of the 21st century from the former Yugoslavia, the former Soviet union, Iraq and Somalia [5] According to data from the Swedish National Board of Health and...

Ngày tải lên: 13/08/2014, 18:21

... plexin-B3CD and fascin-1 211 7.2.2 Significance of direct interaction between plexin-B3CD and RhoGDIα 213 7.2.3 Significance of direct interaction of plexin-B3 and CIPP 214 7.2.4 Binding sites of ... activity of plexins 24 1.2.4 Kinases and kinase receptors in the signaling pathway of plexins 30 1.3 Biological functions of plexins and semaphorins 31 1.3.1 Role of semaphorins and ... 210 7.1 Summary of results 210 7.2 Significance of interactions of pleixn-B3 with fascin-1, RhoGDIα, and CIPP ……………………………………………………………………………… 211 7.2.1 Significance of direct interaction...

Ngày tải lên: 11/09/2015, 09:11

... pay-for-performance relationship for a plan, and the nature of the type of reward offered by a plan, influences employees’ future job performance A weakness of compensation theory, and the compensation literature ... specified for each reward) and the discretion of the supervisor The grids specified ranges of rewards (i.e., a performance rating of could lead to a merit raise of % to %), and thus the specific relationship ... reduce the leverage of high values Employees were also classified as being in one of four bands Bands reflected the level of hierarchy in the compensation system The employee’s band was used as a...

Ngày tải lên: 11/09/2013, 11:44

... facility because of concerns about the water source and the design of the treatment plant (Office of the Auditor Women and Health Care Reform and NNEWH – Women and Water in Canada General of Canada, ... Health Canada and the Department of Indian and Northern Affairs reported that 25 percent of reserve water systems posed a health risk to their communities (Office of the Auditor General of Canada, ... health implications of moves towards privatization and commercialization of water systems are considered in the next section of this report The Significance of Privatization and Commercialization...

Ngày tải lên: 13/02/2014, 06:20