lung carcinoma with bone metastases

Ngày tải lên: 09/08/2014, 07:22

Ngày tải lên: 12/08/2014, 00:20

... there were no obvious pathologi- cal changes in heart, liver, spleen, lung and kidney of trea- ted mice in comparison with animals without treatment (Figure 5B-F). Neither serum markers nor histology ... HRP, transduced LLC cells we re treated with IAA at indicated concentrations in Figure 2D. The results were s hown as the percentage of cell viability with respect to control cells without IAA treatment. LLC ... to adenovirus infection compared with human A549 cells (Figure 2A), w hich was consistent with previous reports [37]. The present study employed LLC cell line since it is syngenic with the immunocompetent...

Ngày tải lên: 18/06/2014, 19:20

... HRP, transduced LLC cells we re treated with IAA at indicated concentrations in Figure 2D. The results were s hown as the percentage of cell viability with respect to control cells without IAA treatment. LLC ... to adenovirus infection compared with human A549 cells (Figure 2A), w hich was consistent with previous reports [37]. The present study employed LLC cell line since it is syngenic with the immunocompetent ... there were no obvious pathologi- cal changes in heart, liver, spleen, lung and kidney of trea- ted mice in comparison with animals without treatment (Figure 5B-F). Neither serum markers nor histology...

Ngày tải lên: 20/06/2014, 03:20

... in bone metastases, correlating with the PSA response and ALP activity and offering a potential imaging biomarker for monitoring treatment response in bone metastases following treatment with 223 Ra-chloride. Background Prostate ... of measuring changes in the uptake of 18 F-fluoride with PET in patients with bone metastases from prostate cancer receiving systemic therapy with 223 Ra-chloride. Addi- tionally, it has shown ... [1]. Bone metas tases are common in patients with prostate cancer, and approximately 70% of patients have evidence of skeletal disease at post-mortem [2]. Bone metastases are associated with...

Ngày tải lên: 21/06/2014, 02:20

Ngày tải lên: 09/08/2014, 09:20

Ngày tải lên: 11/08/2014, 21:22

... nerves due to metastases in the bones. Less often, pain is caused by fractures. Cancer can cause bones to weaken and break. Not all bone metastases result in pain. 8. Q. How are bone metastases ... radiopharmaceutical (a drug that targets radiation to bone metastases) in development for the treatment of men with bone metastases. Osteoporosis in Men with Prostate Cancer 14. Q. What is osteoporosis? ... A. Bone metastases from prostate cancer can be found by a number of tests. Bone scan is the standard method for detecting bone metastases from prostate cancer. It is highly sensitive. A bone...

Ngày tải lên: 15/03/2014, 01:20

... tumor. Lytic metastases are the thinned areas of bone that are found when cancer cells spread into and grow within bone tissue. Blastic metastases are the thicker-than-normal bone that may ... Breast Cancer, Bone Metastases, & Treatment-Related Bone Loss A Publication of The Bone and Cancer Foundation The Relationship Between Breast Cancer and Bone Health ... treatment-related bone loss. Diagnosing bone loss. To make sure bone loss is identified quickly, breast cancer patients should receive bone mineral density tests every 1 to 2 years. Treating bone loss....

Ngày tải lên: 29/03/2014, 01:20

... treatment with Pycnogenol Ò in combination with selenite. (A) TrxR activity and (B) GPx activity in U1285 cell homogenates treated with Pycnogenol ề alone (25 lgặmL )1 ) or in combination with 5 ... cells (U1285, a small-cell lung carcinoma cell line [36]) were cultured in RPMI-1640 medium with GlutaMAX-1 and 25 mm Hepes (Invitrogen, Paisley, UK), supplemented with 10% heat-inactivated fetal ... hydrogen peroxide when added in combination with compounds known to pro- duce ROS, including selenite (Fig. 3). Even though our findings are based on use of a lung carcinoma cell line, we strongly believe...

Ngày tải lên: 30/03/2014, 02:20

... survival due to modification with SVV. Finally, we found that, although modification with SVV further reduced the infarct volume after MACO when compared with transplantation with GFP-MSCs, the extent ... respectively, when compared with group GFP. Expression of VEGF and bFGF in the ischemic tissue were further up-regulated by modification with SVV. Moreover, modification with SVV further reduced ... in lung are activated to secrete the anti-inflammatory protein TSG-6. stem cell 2009, 5:54-63. doi:10.1186/1479-5876-9-105 Cite this article as: Liu et al.: Effects of transplantation with bone marrow-derived...

Ngày tải lên: 18/06/2014, 19:20

... survival due to modification with SVV. Finally, we found that, although modification with SVV further reduced the infarct volume after MACO when compared with transplantation with GFP-MSCs, the extent ... occlu- sion (MCAO) was established with the modified Longa method [13]. Rats were initially anesthetized with 10% chloral hydrate. Rectal temperature was controlled at 37°C with a feedback-regulated water ... were prepared from rat bone marrow as described by Friedenstein et al [9]. In brief, we eutha- nized Sprague Dawley (SD) rats weighted 80-100 g and harvested bone marrow. Bone marrow cells were...

Ngày tải lên: 20/06/2014, 04:20

... compared with patients with chronic respiratory failure without cor pulmonale or controls [32,33]. In patients with idiopathic pulmonary hypertension, BNP was elevated and was co rrelated with the ... of BNP levels with RV dilatation and with patient outcomes (mortality) in patients with ALI. Although BNP levels were elevated in patients with ALI, there was no asso- ciation with RV dilatation ... et al.: Clinical significance of elevated B- type natriuretic peptide in patients with acute lung injury with or without right ventricular dilatation: an observational cohort study. Annals of Intensive...

Ngày tải lên: 21/06/2014, 03:20

... Bone Sarcomas and Bone Metastases (Part 1) Harrison's Internal Medicine > Chapter 94. Soft Tissue and Bone Sarcomas and Bone Metastases Soft Tissue and Bone Sarcomas and Bone Metastases: ... Factors Sarcomas in bone or soft tissues occur in patients who are treated with radiation therapy. The tumor nearly always arises in the irradiated field. The risk increases with time. Viruses ... is extremely rare, with the exception that malignant peripheral nerve sheath tumors (neurofibrosarcoma, malignant schwannoma) can arise from neurofibromas in patients with neurofibromatosis....

Ngày tải lên: 07/07/2014, 02:20

... disease, but a small number of patients with metastases can also be cured. Most patients with stage IV disease die within 12 months, but some patients may live with slowly progressive disease for ... persistent or growing masses should be biopsied, either by Chapter 094. Soft Tissue and Bone Sarcomas and Bone Metastases (Part 2) Classification Approximately 20 different groups of sarcomas ... common site of metastases. Exceptions are GISTs, which metastasize to the liver; myxoid liposarcomas, which seek fatty tissue; and clear- cell sarcomas, which may metastasize to bones. Central...

Ngày tải lên: 07/07/2014, 02:20

... excision of metastases. The two most active chemotherapeutic agents are doxorubicin and ifosfamide. These drugs show a steep dose-response relationship in sarcomas. Gemcitabine with or without ... patients are managed primarily with chemotherapy, with or without other modalities. Surgery Soft tissue sarcomas tend to grow along fascial planes, with the surrounding soft tissues compressed ... treated with surgery alone. Stage II patients are considered for adjuvant radiation therapy. Stage III patients may benefit from adjuvant chemotherapy. Stage IV patients are managed primarily with...

Ngày tải lên: 07/07/2014, 02:20

... M1a Lung M1b Other distant sites Histologic grade (G) GX Grade cannot be assessed G1 Well differentiated—low grade Chapter 094. Soft Tissue and Bone Sarcomas and Bone Metastases ... Chapter 094. Soft Tissue and Bone Sarcomas and Bone Metastases (Part 4) Bone Sarcomas Incidence and Epidemiology Bone sarcomas are rarer than soft tissue sarcomas; they accounted for only ... 2007. Several benign bone lesions have the potential for malignant transformation. Enchondromas and osteochondromas can transform into chondrosarcoma; fibrous dysplasia, bone infarcts, and Paget's...

Ngày tải lên: 07/07/2014, 02:20

... extension. A chest radiograph and CT scan are used to detect lung metastases. Metastases to the bony skeleton should be imaged by a bone scan. Almost all osteosarcomas are hypervascular. Angiography ... Chapter 094. Soft Tissue and Bone Sarcomas and Bone Metastases (Part 5) Stage Grouping Stage IA T1 N0 M0 G1,2 low grade Stage IB ... preoperative chemotherapy. Pathologic diagnosis is established either with a core-needle biopsy, where feasible, or with an open biopsy with an appropriately placed incision that does not compromise...

Ngày tải lên: 07/07/2014, 02:20

Ngày tải lên: 07/07/2014, 02:20