lunasin a new breast cancer chemopreventive seed peptide

$Báo cáo y học: "Immobilized pH gradient-driven paper-based IEF: a new method for fractionating complex peptide mixtures before MS analysis" pdf$

Báo cáo y học: "Immobilized pH gradient-driven paper-based IEF: a new method for fractionating complex peptide mixtures before MS analysis" pdf

Ngày tải lên : 13/08/2014, 13:20

... Innovative Molecular Analysis Technologies (IMAT) program of the National Cancer Institute, National Institutes of Health, Grant #R33 CA092731 Author details Department of Pathology and Laboratory ... iTRAQ ratio before plotting, and the y axis represents the iTRAQ ratio The x axis appears thick because each protein is represented by a small vertical bar (>800 such bars are juxtaposed along ... issues of iTRAQ quantitation accuracy (defined as being close to the true value and measured by statistical mean) and precision (defined as reproducibility and measured by standard deviation) [28-32]...

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báo cáo hóa học: " Syndecan-1 antigen, a promising new target for triple-negative breast cancer immuno-PET and " potx

Ngày tải lên : 21/06/2014, 01:20

... GL, Horak ID, Goldenberg DM: Preclinical therapy of breast cancer with a radioiodinated humanized anti-EGP-1 monoclonal antibody: advantage of a residualizing iodine radiolabel Breast Cancer Res ... in several cancer types, including breast, colorectal, gastric, pancreatic, prostate, lung, endometrial, and ovarian cancers, as well as squamous cell carcinoma of the head and neck and multiple ... in conservatively managed triple negative early-stage breast cancer J Clin Oncol 2006, 24(36):5652-5657 11 Oakman C, Viale G, Di Leo A: Management of triple negative breast cancer Breast 2010,...

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Báo cáo y học: " Clustering of sebaceous gland carcinoma, papillary thyroid carcinoma and breast cancer in a woman as a new cancer susceptibility disorder: a case report" pptx

Ngày tải lên : 11/08/2014, 17:21

... gland carcinoma, papillary thyroid carcinoma, and breast cancer Her mother who died at age 73 and maternal aunt who died at age 67 with a diagnosis of breast at around age 50, were both diagnosed ... inoperable brain tumor, and a male and a female paternal second degree cousin had breast cancer However, her family history was negative for colon cancer, endometrial or ovarian cancers, thyroid cancer, ... pathognomonic mucocutaneous lesions such as facial trichilemmomas, acral keratoses and papillomatosis; hamartomatous polyps, and internal visceral malignancies including breast and thyroid cancer...

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Báo cáo y học: "Gain of a 500-fold sensitivity on an intravital MR Contrast Agent based on an endohedral Gadolinium-Cluster-Fullerene-Conjugate: A new chance in cancer diagnostics"

Ngày tải lên : 26/10/2012, 09:07

... of heavy ions demands absolute reliability of new diagnostics and treatment planning for prostate and brain tumors By the fact that the rare earth metals trapped inside of the carbon cage are ... Gd@C60[C(COOH)2]10 as a MRI contrast agent J Am Chem Soc 2003; 125: 5471-8 Okumura M, Mikawa M, Yokawa T, et al Evaluation of water-soluble metallofullerenes as MRI contrast agents Acad Radiol 2002; ... Then the organic phase was washed with water, followed by 1N-HCl and again water The organic layer was dried over Na2SO4 and evaporated The resulting residue was chromatographed on silicagel by elution...

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Tài liệu Voices of Fear and Safety¿ Women¿s ambivalence towards breast cancer and breast health: a qualitative study from Jordan pdf

Ngày tải lên : 13/02/2014, 06:20

... “Voices of Fear and Safety” Women’s ambivalence towards breast cancer and breast health: a qualitative study from Jordan Hana Taha1,2,3* Email: hana.taha@ki.se Raeda Al-Qutob4,5 Email: raeda@johud.org.jo ... American Cancer Association: Survival rates for breast cancer Atlanta: 2012 http://www .cancer. org /Cancer/ BreastCancer/OverviewGuide /breastcancer- overviewsurvival-rates Jordan Ministry of Health: ... Foundation, Amman, Jordan Abstract Background Breast cancer is the leading cause of cancer mortality among Jordanian women Breast malignancies are detected at late stages as a result of deferred breast...

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Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx

Ngày tải lên : 21/02/2014, 15:20

... to a MUC-1 that has only part of its carbohydrate chains removed [10] It was later shown on a molecular level that a small oligosaccharide attached to Thr3 enhances binding afﬁnity of glycopeptides ... assumed to have equal intensity Proton pair ˚ Lower limit (A) ˚ Upper limit (A) Asp2 -a/ Thr3-NH* GalNAc-H1/Thr3-NH* Pro5-dd¢/Arg4-cc¢ Arg4 -a/ Arg4-dd¢ Arg4 -a/ Arg4-cc¢ Arg4 -a/ Pro5-dd¢ Arg4-bb¢/Arg4-dd¢ ... each separated by a ms delay, leading to a total saturation time of 2.04 s The pulse scheme is as follows: relaxation delay, presaturation pulse train, (p/2), spin lock (where applicable), acquisition...

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Breast cancer risk in relation to occupations with exposure to carcinogens and endocrine disruptors: a Canadian case–control study pptx

Ngày tải lên : 06/03/2014, 02:21

... Luginaah I, Laukkanen E, Hellyer D, Reinhartz A, Watterson A, Abu-Zahra H, Maticka-Tyndale E, Schneider K, Beck M, Gilbertson M: Occupation and breast cancer: a Canadian case– control study Ann ... and other mechanistic aspects of breast carcinogenesis [69] Menopausal status Finding distinct patterns for pre- versus postmenopausal breast cancer, such as increased premenopausal breast cancer ... JA, Terry MB, Wang LW, Wang Q, Stellman SD, Beyea J, Hatch M, Kabat GC, Wolff MS, Levin B, Neugut AI, Santella RM: Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysis...

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New Malignancies Following Breast Cancer docx

Ngày tải lên : 06/03/2014, 02:21

... Giordano SH 2005 A review of the diagnosis and management of male breast cancer Oncologist 10(7):471-479 Murakami R, Hiyama T, Hanai A, et al 1987 Second primary cancers following female breast cancer ... lumpectomy or mastectomy for primary breast carcinoma Cancer 97(6):1404-1411 Zablotska LB, Chak A, Das A, et al 2005 Increased risk of squamous cell esophageal cancer after adjuvant radiation therapy for ... SURVIVORS: SEER CANCER REGISTRIES, 1973–2000 NEW MALIGNANCIES FOLLOWING BREAST CANCER Male Breast Cancer Breast cancer among men is uncommon, accounting for less than 1% of breast cancers in the...

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Occupation and Breast Cancer: A Canadian Case–Control Study docx

Ngày tải lên : 06/03/2014, 02:21

... Cancer Research (LHBCR) by the Canadian Breast Cancer Foundation and the Breast Cancer Society of Canada REFERENCES DAVIS, D.L., D AXELROD, L BAILEY, et al 1998 Rethinking breast cancer risk and the ... research grant from Canadian Breast Cancer Research Foundation—Ontario Chapter 60 BROPHY, J., M KEITH, I LUGINAAH, et al 2003 Occupational histories of breast cancer patients year research grant ... Classification Ottawa, Canada 16 STATISTICS CANADA 1998 North American Industrial Classification System Ottawa, Canada 17 CHECKOWAY, H., N PEARCE & D CRAWFORD-BROWN 1989 Research Methods in Occupational...

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Báo cáo khoa học: Synthesis and characterization of a new and radiolabeled high-afﬁnity substrate for H+/peptide cotransporters pdf

Ngày tải lên : 07/03/2014, 05:20

... strates of H+ ⁄ peptide cotransporters, such as Gly-Sar, Ala-Ala, Lys-Lys, Ala-Asp, d-Phe-Ala, Ala-Ala-Ala, d-aminolevulinic acid, cefadroxil and Ala-4-nitroanilide (all 100 lm, Table 1) Glycine, ... standard error, n ¼ Lys[Z(NO2)]-Val, Lys(4-nitrobenzyloxycarbonyl)-Val Compound Bip-[3H]Pro uptake (%) Control Gly Gly-Sar Bip-Pro Ala-Ala Pro-Ala Lys-Lys Ala-Asp D-Phe-Ala Ala-Ala-Ala d-Aminolevulinic ... [Gly1-14C]Gly-Sar (speciﬁc radioactivity 53 mCiÆ mmol)1) was custom synthesized by Amersham International (Little Chalfont, UK) Dexamethasone, apotransferrin, Gly-Gln, AlaAla, Ala-Ala-Ala, Lys-Lys, d-aminolevulinic...

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Management of breast cancer in women: A national clinical guideline ppt

Ngày tải lên : 08/03/2014, 14:20

... mortality or breast cancer mortality after mastectomy alone or mastectomy plus axillary clearance Radiotherapy did reduce all cause mortality and breast cancer mortality after mastectomy plus axillary ... treated breast and new primary in the contralateral breast Relapses in the treated breast are detected clinically or mammographically Mammography is the gold standard method of imaging for cancer ... non -cancer related deaths, such as vascular deaths Excess vascular deaths are also evident from two years after radiotherapy, but are particularly significant if more than 10 years have elapsed after...

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Cornell University Program on Breast Cancer and Environmental Risk Factors in New York State (BCERF) pptx

Ngày tải lên : 15/03/2014, 01:20

... Breast Cancer and Environmental Risk Factors in New York State Smoking has effects that can both increase and decrease breast cancer risk On one hand, tobacco smoke contains chemicals that can cause ... women, as well as leukemia and brain cancer in children, have been reported Does smoking at a young age or being passively exposed to tobacco smoke at a young age affect a woman’s breast cancer ... Program on Breast Cancer and Environmental Risk Factors in New York State breast cancer risk There is direct documentation that breasts are exposed to chemicals within tobacco smoke in active...

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Báo cáo khoa học: An estrogen receptor a suppressor, microRNA-22, is downregulated in estrogen receptor a-positive human breast cancer cell lines and clinical samples pptx

Ngày tải lên : 22/03/2014, 21:20

... Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y & Takahashi T (2006) A polycistronic microRNA cluster, miR-17-92, is overexpressed in human ... 5¢-GUG GAUAUUGUUGCCAUCA-3¢ The sequences of two siRNAs for ESR1 are as follows: ERa siRNA #2 sense strand 5¢-UCAUCGCAUUCC UUGCAAAdTdT-3¢, antisense strand 5¢- UUUGCAAGGAAUGCGAUGAdTdT-3¢; ERa siRNA ... analyzed for ERa mRNA expression by quantitative RT-PCR at 48 h after transcription The data were normalized against the expression of GAPDH mRNA Data are presented as mean ± standard deviation...

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Targeting New Pathways and Cell Death in Breast Cancer Edited by Rebecca L. Aft docx

Ngày tải lên : 23/03/2014, 17:20

... Chapter Cell Cycle Regulatory Proteins in Breast Cancer: Molecular Determinants of Drug Resistance and Targets for Anticancer Therapies 113 Aamir Ahmad, Zhiwei Wang, Raza Ali, Bassam Bitar, Farah ... LTED breast cancer cells Death Receptor pathway FasL E2 Estradiol Fas Bcl-2 FADD Mitochondria Caspase NF-κB HER2/neu Cytochrome C Apaf1 Bax Bim Bak P53 NOXA GADD45 GADD45 Caspase Caspase Caspase ... (Avastin/Bevacizumab) have found their clinical applications in the war against breast cancers (Schlotter et al, 2008) In particular, as a well-documented adjuvant drug for metastatic breast cancer...

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Delayed presentation in breast cancer: a study in Iranian women docx

Ngày tải lên : 28/03/2014, 14:20

... www-dep.iarc.fr/globocan/globocan.html] Jarvandi S, Montazeri A, Harirchi I and Kazemnejad A: Beliefs and behaviours of Iranian teachers toward early detection of breast cancer and breast self-examination ... operable breast cancer patients Eur J Cancer Prev 2001, 10:53-59 Ebrahimi M, Vahdaninia M and Montazeri A: Risk factors for breast cancer in Iran: a case-control study Breast Cancer Research 2002, ... biased, especially in cases with longer delay Another limitation was that there were no data for patients' knowledge and attitudes towards breast cancer Health beliefs and knowledge of breast cancer...

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Breast Cancer In Younger Women - Proceedings Of A Conference Held At The National Institutes Of Health, Bethesda, Maryland, January 28, 1993 pot

Ngày tải lên : 28/03/2014, 23:20

... Ecuador El Salvador Granada Guatemala Guyana Haití Honduras Jamaica México Nicaragua Panamá Paraguay Perú República Dominicana Saint Kitts y Nevis San Vicente y las Granadinas Santa Luc a Surinam ... PAÍSES INDUSTRIALIZADOS Alemania Andorra Australia Austria Bélgica Canadá Chipre Dinamarca Eslovaquia Eslovenia Espa a Estados Unidos Estonia Finlandia Francia Grecia Hungr a Irlanda Islandia ... sistemas no dan abasto debido al SIDA y a la mortalidad asociada esta enfermedad En última instancia, aunque las causas de la mortalidad materna y de las lesiones y discapacidades relacionadas el...

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Breast cancer incidence and case fatality among 4.7 million women in relation to social and ethnic background: a population-based cohort study pdf

Ngày tải lên : 29/03/2014, 01:20

... decreasing breast cancer case fatality over the last decades in native Swedes and immigrants but not in immigrants’ daughters We found disparities in breast cancer case fatality by age at diagnosis ... http:/ /breastcancer- research.com/content/14/1/R5 Page of 13 Table Hazard ratio (HR) of case fatality of breast cancer by education, calendar year and area of diagnosis Immigrants Death HR* (95% CI) Immigrants’ daughters Death HR* (95% ... equal access to a uniform health care system, indicating higher breast cancer mortality among socio-economically disadvantaged women [53-56] It has already been shown that breast cancer mortality...

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Reducing the Risk of Breast Cancer With Medicine: A Guide for Women potx

Ngày tải lên : 29/03/2014, 01:20

... women are born with a gene that puts them at high risk for breast cancer Having radiation treatment at a young age also raises the risk Learning About Breast Cancer Breast cancer is a malignant ... older raises the risk of breast cancer Family history Having a mother, sister, or daughter who had breast cancer raises the risk Breast biopsy history Having an abnormal finding on a past breast ... cover treatments for women who already have breast cancer Risk of Breast Cancer Most women will never get breast cancer A woman’s risk of breast cancer depends on her age and other risk factors...

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báo cáo hóa học:" PAR1 is selectively over expressed in high grade breast cancer patients: a cohort study" docx

Ngày tải lên : 18/06/2014, 15:20

... thank Margarita Alvarez for technical support processing paraffin samples and Alejandro Cabrera for invaluable help using Stata program References Bray F, Ferlay J, Pisan P, Parkin DM: Global CancerStatistics ... functional PAR1, PAR2, and PAR4 Another human carcinoma breast cancer cell line, MCF-7, which is minimally invasive, expresses only trace amounts of PAR1 and low levels of PAR2 and PAR4 These data are ... IIB-stage cancer In contrast, of the 21 PAR1-negative patients, only six (29%) had IIIA-stage or greater cancer, whereas 15 (71%) had IIB-stage or lower cancer We also performed a multivariate analysis...

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Báo cáo hóa học: " Cathepsin B: a potential prognostic marker for inflammatory breast cancer" ppt

Ngày tải lên : 18/06/2014, 16:20

... Lejeune C, Romain S, Tubiana N, Beedassy B, Martin PM, Serment H, Piana L: Inflammatory carcinomas of the breast: a clinical, pathological, or a clinical and pathological definition? Int J Cancer 1995, ... 3P4 Canada Department of Medical Oncology, National Cancer Institute, Cairo University, Giza 12613 Egypt 8Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA Authors’ ... Auwera I, Merajver SD, Van Marck EA, van Dam P, Vermeulen PB, Dirix LY, van Golen KL: Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer Breast Cancer...

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