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Báo cáo khoa học: Fluorescence studies of the replication initiator protein RepA in complex with operator and iteron sequences and free in solution pdf

Báo cáo khoa học: Fluorescence studies of the replication initiator protein RepA in complex with operator and iteron sequences and free in solution pdf

... titration. In the fits, the protein concentration was left free, to serve as an indicator of stoichiometry. In the case of 1IR, the fit resulted in a binding stoichi- ometry of 2 : 1, i.e. dimer binding. ... S1), indicating that it is static in nature. We do not have an unequivocal interpretation of the origin of the static quenching. However, judging from the binding stoichi- ometry together with the ... available, indicating secondary struc- tural changes in the linker connecting the dimerization and DNA-binding domains, and rearrangement of the relative orientation of the two domains [7,9]. The con- formational...

Ngày tải lên: 07/03/2014, 04:20

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Tài liệu An overview of the drinking water supply situation in the Mekong river delta, Vietnam pdf

Tài liệu An overview of the drinking water supply situation in the Mekong river delta, Vietnam pdf

... recorded the acidity in the rain water in April, May yearly. No using of rain water in early rainy season is recommended as way to treat the air-dust and other pollutants deposited in the house-roofs ... in the coastal lands of the delta. Saline encroachment effects almost half of the MD. The salinity is caused by sea water intrusion in open mouths and estuaries. The phenomenon of salinity ... bars in the sea in front of the estuaries. Otherwise, in early rainy season, nearly 1,6 million hectares of the delta are infected by the acidity water due to the washing out aluminium and iron...

Ngày tải lên: 20/12/2013, 19:15

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Tài liệu COMING OUT OF THE FOODSHED: CHANGE AND INNOVATION IN RURAL ALASKAN FOOD SYSTEMS pptx

Tài liệu COMING OUT OF THE FOODSHED: CHANGE AND INNOVATION IN RURAL ALASKAN FOOD SYSTEMS pptx

... vulnerability as they manifest in the past and present of Alaska Native foodways. The first paper, ‘Outpost Gardening in Interior Alaska’ examines the historical dimensions of cropping by Athabascan ... high- frequency of forest fires collects within the basin of the Alaskan interior, and during 8 Whether real or perceived, the coldness of river water is mentioned often in BIA reports from schoolteachers ... political economies of cheap food increases, outpost agriculture is finding a renewed niche in emerging indigenous movements against the vulnerabilities embedded within participation in the cheap food...

Ngày tải lên: 13/02/2014, 05:20

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Tài liệu Women of the World Women’''''s Health in India doc

Tài liệu Women of the World Women’''''s Health in India doc

... 1995). In the past few years, there has been an increase in the reported inci- dence of torture — cruelty by the husband and the husband’s rela- tives. The reported number of incidents of torture increased ... compo- nents of the spread of HIV. Sur- veys in some areas show 5 to 10 percent of truck drivers in the country are HIV infected (AIDS Analysis, 1996). Despite the alarming growth of the epidemic, ... to turn to their parents if they leave their husbands because their parents either will not (because of the social stigma) or cannot (because of economics) take them in. Generally, the police have...

Ngày tải lên: 13/02/2014, 06:20

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Tài liệu Đề tài " Geometry of the uniform spanning forest: Transitions in dimensions 4, 8, 12, . . . " pptx

Tài liệu Đề tài " Geometry of the uniform spanning forest: Transitions in dimensions 4, 8, 12, . . . " pptx

... graph obtained from G by contracting the edges in E 1 and delet- ing the edges in E 2 . Let H be the graph obtained from Z d by contracting the edges in K 1 and deleting the edges in K 2 . By ... U(W; x, y) the intersection of U(W) with the event that the path connecting x, y in the USF is edge-disjoint from the oriented USF paths connecting the vertices in V := W \{x, y} to in nity. By ... Υ  R , the paths in F to Υ  R from the vertices in the complement of Υ  R ∪ B(x, R) are conditionally independent of γ R . Therefore the conditional distribution of ζ R given Υ R is just the harmonic...

Ngày tải lên: 14/02/2014, 17:20

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Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

... insulin receptor-interacting region (PIR) [6] and inhibits the tyrosine kinase activity of the IR [7]. On the basis of the crystal structure of the tyrosine kinase domain of the IR in complex with the PIR ⁄ BPS domain ... residues of the IR kinase loop, which help position the PIR–BPS and increase binding affinity [8]. Although the interaction of Grb14 with the IR is probably the major determi- nant of the insulin-induced ... a model for the Grb14–IR interaction. The PIR–BPS binds as a pseudosubstrate inhibitor in the substrate- binding groove of the kinase, whereas the SH2 domain interacts with phosphorylated tyrosine residues...

Ngày tải lên: 18/02/2014, 18:20

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Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx

Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx

... cells were incubated for 24 h either in the absence or in prese nce of FSH, dbcAMP, cholera toxin or bFGF, either in combination with FSH or dbcAMP or cholera toxin and bFGF. Extraction of total ... [5154]. Inhibitory transcription factors that bind to AP-1 or FIN-1 o r that inactive b inding or transactivation capacity of, for example, FIN-1 and USF-1, could explain activation or inhibition of ... partners of bFGF (Eur. J. Biochem. 269) 509 The bFGF binding requires speciđc motifs on highly sulfated HS chains. Sodium chlorate, in inducing structural alteration of HS chains, prevents the bFGF...

Ngày tải lên: 21/02/2014, 03:20

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Báo cáo khoa học: Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions pptx

Báo cáo khoa học: Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions pptx

... results in blocking of the binding of the SH2 domain to the substrate and thereby preventing interaction of the substrate with the kinase domain. For active n-Src in which the C-tail tyrosine was ... demonstrated that intra-domain interactions between Src family kinases (SFKs), stabilized by binding of the phosphorylated C-terminus to the SH2 domain and ⁄ or binding of the SH2 kinase linker to the SH3 ... studies of inactive and active Src, the SH2 and SH3 domains are believed to form a ‘regulatory apparatus’. Binding of the phos- phorylated C-terminus to the SH2 domain and ⁄ or binding of the SH2-kinase...

Ngày tải lên: 06/03/2014, 01:20

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THE FINANCIAL CRISIS INQUIRY REPORT - Final Report of the National Commission on the Causes of the Financial and Economic Crisis in the United States docx

THE FINANCIAL CRISIS INQUIRY REPORT - Final Report of the National Commission on the Causes of the Financial and Economic Crisis in the United States docx

... ∞ THE FINANCIAL CRISIS INQUIRY REPORT FINAL REPORT OF THE NATIONAL COMMISSION ON THE CAUSES OF THE FINANCIAL AND ECONOMIC CRISIS IN THE UNITED STATES OFFICIAL GOVERNMENT EDITION THE FINANCIAL ... Oce of the Comptroller of the Cur- rency and the Oce of Thrift Supervision, caught up in turf wars, preempted state regulators from reining in abuses. CONCLUSIONS OF THE FINANCIAL CRISIS INQUIRY ... this inquiry. In the course of its research and investigation, the Commission reviewed millions of pages of documents, interviewed more than  witnesses, and held  days of public hearings in...

Ngày tải lên: 06/03/2014, 09:22

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Lord of the World docx

Lord of the World docx

... his mind, pro- gress lay in the merging of the individual in the family, of the family in the commonwealth, of the commonwealth in the continent, and of the continent in the world. Finally, the ... after the renewed German attacks in the twenties; and the Divinity of our Lord, some think, had gone all but in name by the beginning of the century. The Kenotic theory had provided for that. Then ... hydraulic power into the centre of the dining-table, had be- come universal in the houses of the well-to-do. The floor consisted en- tirely of the asbestos cork preparation invented in America, noiseless, clean,...

Ngày tải lên: 06/03/2014, 15:20

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Báo cáo khoa học: Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L) pot

Báo cáo khoa học: Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L) pot

... However, the amino acids forming the catalytically active center of the A-chains of the MLp toxins are fully conserved and retained in corresponding positions, as in the A-chain of ricin [27] ... Gln256 of the ricin B-chain in the second sugar binding site [28]. The exceptions are the replacement of Trp38 fi Ser in the ML2p B-chain and Tyr252 fi Phe in the ML3p B-chain (Fig. 2). The highly ... ricin [40]. The introduced mutation of Trp37 fi Ser noticeably decreased the efficiency of its binding to Gal. In the second binding site of the ML3p and ML3.1p B-subunits, the replacement of the...

Ngày tải lên: 07/03/2014, 15:20

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The Bravest of the Brave or, with Peterborough in Spain pot

The Bravest of the Brave or, with Peterborough in Spain pot

... of all classes, the hatred of the Commons, the defection of the Lords, the alarm of the Church, and the wavering loyalty of the army. William, however, was already informed of these facts, and ... dispute being the succession to the crown of Spain, England's feelings in the matter being further imbittered by the recognition by Louis XIV of the Pretender as King of England. Therefore, although ... conditions of this treaty became known they inspired natural indignation in the minds of the people of the country which had thus been arbitrarily allotted, and the dying Charles of Spain was infuriated...

Ngày tải lên: 08/03/2014, 15:20

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Report of the Director-General on developments in the maritime sector pot

Report of the Director-General on developments in the maritime sector pot

... interest in improving working and living conditions in the shipping industry. The Office’s programme on decent work in the maritime industry played a major role in improving the promotion of ... relating to the health of seafarers, often through the Joint ILO/WHO Committee on the Health of Seafarers. Since the Committee’s last meeting in 1993, 3 the two Organizations held, in 1997, the ... view to reducing the prevalence of gender stereotypes within the industry. Training 145. For the purpose of guaranteeing equality of opportunity and treatment in access to training, maritime...

Ngày tải lên: 08/03/2014, 17:20

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Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt

Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt

... is the shift of the pH optimum from near neutral in the wild-type to pH 9.2 in the R389A mutant, which is in accord with an increase in the pK of Y229 if the stabilizing R389 residue is lacking. ... coordination to the other ligands of the binding site (center I), but the binding becomes much weaker as emphasized by the dramatic increase of the Na + ion concentration required to saturate the enzyme. ... carboxybiotin, or slow Na + move- ment through the channel to its binding site. Following the decarboxylation of carboxybiotin in the reaction cycle (Fig. 4B,C), the biotin prosthetic group leaves the...

Ngày tải lên: 08/03/2014, 23:20

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