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Báo cáo khoa học: Fluorescence studies of the replication initiator protein RepA in complex with operator and iteron sequences and free in solution pdf
... titration. In the fits, the protein concentrationwas left free, to serve as an indicator of stoichiometry. In the case of 1IR, the fit resulted in a binding stoichi-ometry of 2 : 1, i.e. dimer binding. ... S1),indicating that it is static in nature. We do not havean unequivocal interpretation of the origin of the staticquenching. However, judging from the binding stoichi-ometry together with the ... available, indicating secondary struc-tural changes in the linker connecting the dimerizationand DNA-binding domains, and rearrangement of the relative orientation of the two domains [7,9]. The con-formational...
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Tài liệu An overview of the drinking water supply situation in the Mekong river delta, Vietnam pdf
... recorded the acidity in the rain water in April, May yearly. No using of rain water in early rainy season is recommended as way to treat the air-dust and other pollutants deposited in the house-roofs ... in the coastal lands of the delta. Saline encroachment effects almost half of the MD. The salinity is caused by sea water intrusion in open mouths and estuaries. The phenomenon of salinity ... bars in the sea in front of the estuaries. Otherwise, in early rainy season, nearly 1,6 million hectares of the delta are infected by the acidity water due to the washing out aluminium and iron...
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Tài liệu COMING OUT OF THE FOODSHED: CHANGE AND INNOVATION IN RURAL ALASKAN FOOD SYSTEMS pptx
... vulnerability as they manifest in the past and present of Alaska Native foodways. The first paper, ‘Outpost Gardening in Interior Alaska’ examines the historical dimensions of cropping by Athabascan ... high-frequency of forest fires collects within the basin of the Alaskan interior, and during 8 Whether real or perceived, the coldness of river water is mentioned often in BIA reports from schoolteachers ... political economies of cheap food increases, outpost agriculture is finding a renewed niche in emerging indigenous movements against the vulnerabilities embedded within participation in the cheap food...
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Tài liệu Women of the World Women''''s Health in India doc
... 1995). In the past few years, there has beenan increase in the reported inci-dence of torture — cruelty by the husband and the husband’s rela-tives. The reported number of incidents of torture increased ... compo-nents of the spread of HIV. Sur-veys in some areas show 5 to 10percent of truck drivers in the country are HIV infected (AIDSAnalysis, 1996).Despite the alarming growth of the epidemic, ... to turn to theirparents if they leave their husbandsbecause their parents either will not(because of the social stigma) orcannot (because of economics)take them in. Generally, the policehave...
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Tài liệu Đề tài " Geometry of the uniform spanning forest: Transitions in dimensions 4, 8, 12, . . . " pptx
... graph obtained from G by contracting the edges in E1and delet-ing the edges in E2. Let H be the graph obtained from Zdby contracting the edges in K1and deleting the edges in K2. By ... U(W; x, y) the intersection of U(W) with the event that the path connecting x, y in the USFis edge-disjoint from the oriented USF paths connecting the vertices in V :=W \{x, y} to in nity. By ... ΥR, the paths in F to ΥRfrom the vertices in the complement of ΥR∪ B(x, R) are conditionally independent of γR. Therefore the conditional distribution of ζRgiven ΥRis just the harmonic...
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Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx
... insulinreceptor-interacting region (PIR) [6] and inhibits the tyrosine kinase activity of the IR [7]. On the basis of the crystal structure of the tyrosine kinase domain of the IR in complex with the PIR ⁄ BPS domain ... residues of the IR kinase loop, which help position the PIR–BPS andincrease binding affinity [8]. Although the interaction of Grb14 with the IR is probably the major determi-nant of the insulin-induced ... amodel for the Grb14–IR interaction. The PIR–BPSbinds as a pseudosubstrate inhibitor in the substrate-binding groove of the kinase, whereas the SH2 domaininteracts with phosphorylated tyrosine residues...
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Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx
... cells were incubated for 24 heither in the absence or in prese nce of FSH, dbcAMP,cholera toxin or bFGF, either in combination with FSH ordbcAMP or cholera toxin and bFGF.Extraction of total ... [5154]. Inhibitory transcription factorsthat bind to AP-1 or FIN-1 o r that inactive b inding ortransactivation capacity of, for example, FIN-1 and USF-1,could explain activation or inhibition of ... partners of bFGF (Eur. J. Biochem. 269) 509 The bFGF binding requires speciđc motifs on highlysulfated HS chains. Sodium chlorate, in inducing structuralalteration of HS chains, prevents the bFGF...
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Báo cáo khoa học: Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions pptx
... results in blocking of the binding of the SH2 domain to the substrate and thereby preventing interaction of the substrate with the kinase domain. For active n-Src in which the C-tail tyrosine was ... demonstrated that intra-domain interactions betweenSrc family kinases (SFKs), stabilized by binding of the phosphorylatedC-terminus to the SH2 domain and ⁄ or binding of the SH2 kinase linker to the SH3 ... studies of inactive andactive Src, the SH2 and SH3 domains are believed toform a ‘regulatory apparatus’. Binding of the phos-phorylated C-terminus to the SH2 domain and ⁄ orbinding of the SH2-kinase...
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THE FINANCIAL CRISIS INQUIRY REPORT - Final Report of the National Commission on the Causes of the Financial and Economic Crisis in the United States docx
... ∞ THE FINANCIAL CRISISINQUIRY REPORTFINAL REPORT OF THE NATIONAL COMMISSION ON THE CAUSES OF THE FINANCIAL AND ECONOMIC CRISIS IN THE UNITED STATESOFFICIAL GOVERNMENT EDITION THE FINANCIAL ... Oce of the Comptroller of the Cur-rency and the Oce of Thrift Supervision, caught up in turf wars, preempted stateregulators from reining in abuses. CONCLUSIONS OF THE FINANCIAL CRISIS INQUIRY ... this inquiry. In the course of its research and investigation, the Commission reviewed millions of pages of documents, interviewed more than witnesses, and held days of public hearings in...
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Lord of the World docx
... his mind, pro-gress lay in the merging of the individual in the family, of the family in the commonwealth, of the commonwealth in the continent, and of the continent in the world. Finally, the ... after the renewed German attacks in the twenties; and the Divinity of our Lord, some think, had gone all but in name by the beginning of the century. The Kenotic theory had provided for that. Then ... hydraulic power into the centre of the dining-table, had be-come universal in the houses of the well-to-do. The floor consisted en-tirely of the asbestos cork preparation invented in America, noiseless,clean,...
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Báo cáo khoa học: Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L) pot
... However, the amino acidsforming the catalytically active center of the A-chains of the MLp toxins are fully conserved and retained in corresponding positions, as in the A-chain of ricin [27] ... Gln256 of the ricin B-chain in the second sugar binding site [28]. The exceptions are the replacement of Trp38 fi Ser in the ML2p B-chain andTyr252 fi Phe in the ML3p B-chain (Fig. 2). The highly ... ricin [40]. The introduced mutation of Trp37 fi Ser noticeably decreased the efficiency of its binding to Gal. In the second binding site of the ML3p and ML3.1p B-subunits, the replacement of the...
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The Bravest of the Brave or, with Peterborough in Spain pot
... of all classes, the hatred of the Commons, the defection of the Lords, the alarm of the Church, and the wavering loyalty of the army.William, however, was already informed of these facts, and ... dispute being the succession to the crown of Spain, England's feelings in the matterbeing further imbittered by the recognition by Louis XIV of the Pretender as King of England. Therefore,although ... conditions of this treaty became known theyinspired natural indignation in the minds of the people of the country which had thus been arbitrarily allotted,and the dying Charles of Spain was infuriated...
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Report of the Director-General on developments in the maritime sector pot
... interest in improving working and living conditions in the shipping industry. The Office’s programme on decent work in the maritime industry played a major role in improving the promotion of ... relating to the health of seafarers, often through the Joint ILO/WHO Committee on the Health of Seafarers. Since the Committee’s last meeting in 1993, 3 the two Organizations held, in 1997, the ... view to reducing the prevalence of gender stereotypes within the industry. Training 145. For the purpose of guaranteeing equality of opportunity and treatment in access to training, maritime...
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Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt
... is the shift of the pH optimumfrom near neutral in the wild-type to pH 9.2 in the R389Amutant, which is in accord with an increase in the pK of Y229 if the stabilizing R389 residue is lacking. ... coordination to the otherligands of the binding site (center I), but the bindingbecomes much weaker as emphasized by the dramaticincrease of the Na+ion concentration required to saturate the enzyme. ... carboxybiotin, or slow Na+move-ment through the channel to its binding site.Following the decarboxylation of carboxybiotin in the reaction cycle (Fig. 4B,C), the biotin prosthetic group leavesthe...
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