long life is associated with increased resistance to stress
Báo cáo y học: " Endothelial Endotoxemia related to cardiopulmonary bypass is associated with increased risk of infection after cardiac surgery: a prospective observational stud" pptx
... Thus, this period of endotoxemia represents the first “hit” in a two “hit” model of risk Faist et al first used this “two hit” hypothesis to describe the increased risk of development of sepsis in ... largely been disappointing Strategies have included antagonists to the endotoxin Toll-like receptor (TLR4), extracorporeal endotoxin removal systems, performance “off pump” cardiac surgery to eliminate ... levels Importantly, endotoxemia at the conclusion of CPB is associated with a significant risk of the development of postoperative infections Further research is necessary to assess whether a targeted...
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báo cáo hóa học: " Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?" doc
... depression [13] This hypothesis is based on the observation that the above mentioned proinflammatory cytokines induce a shift from serotonin synthesis to tryptophan Page of metabolism via the kynurenine ... application for double immunohistochemistry J Histochem Cytochem 1982, 30:1079-1082 37 Polak M, Haymaker W, Johnson JE, D’Amelio F: Neuroglia and their reactions In Histology and Histopathology of the Nervous ... imbalances are associated with acute disease phases In a postmortem study of chronically stable patients with MDD or BD, transient microglial changes may be missed account for the histo-architectural...
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Báo cáo y học: "Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD" ppsx
... measured by ELISA using respective duo-antibody kits (R&D Systems, Minneapolis, MN) according to the manufacturer’s instructions Immunohistochemical staining for tissue macrophages Immunohistochemical ... susceptible to increased lung inflammatory cell influx in response to CS Augmented inflammatory response in the lung from environmental stress or toxicants results in the activation of inflammatory ... exposure augments the proinflammatory cytokine levels in lungs of ApoE-/- mice In order to confirm whether the inflammatory cell influx was associated with proinflammatory cytokine release in ApoE-/-...
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Báo cáo y học: "Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD" potx
... measured by ELISA using respective duo-antibody kits (R&D Systems, Minneapolis, MN) according to the manufacturer’s instructions Immunohistochemical staining for tissue macrophages Immunohistochemical ... susceptible to increased lung inflammatory cell influx in response to CS Augmented inflammatory response in the lung from environmental stress or toxicants results in the activation of inflammatory ... exposure augments the proinflammatory cytokine levels in lungs of ApoE-/- mice In order to confirm whether the inflammatory cell influx was associated with proinflammatory cytokine release in ApoE-/-...
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báo cáo khoa học: " Timing is everything: early degradation of abscission layer is associated with increased seed shattering in U.S. weedy rice" doc
... rice has a distinct mechanistic basis from that of the shattering wild ancestor of rice, consistent with the reevolution of this trait in weedy groups from domesticated ancestors Surprisingly, independently ... by Toluidine Blue O Protoplasma 1964, 59:367-373 doi:10.1186/1471-2229-11-14 Cite this article as: Thurber et al.: Timing is everything: early degradation of abscission layer is associated with ... easily with the floral tissue at flowering The lack of an abscission layer at flowering in all three indica cultivated accessions is consistent with their lack of shattering (average BTS = 70 to...
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Báo cáo y học: "Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment" potx
... NM_000577 Interleukin receptor antagonist IRF2 NM_002199 Interferon regulatory factor IRF7 NM_001572 Interferon regulatory factor X X X X X X X X X X ISG15 NM_005101 ISG15 ubiquitin-like modifier ... response to infliximab treatment is associated with treatmentinduced increase in type I IFN response gene activity Discussion In this study, we demonstrated that blockade of the inflammatory cytokine ... divided into two groups (ratio < and ratio > 1) on the basis of their IFN response upon TNF blockade and compared with each other with respect to clinical response to treatment The ratio is determined...
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Báo cáo y học: "(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis" ppsx
... expression is increased in response to inflammatory markers, LDL and oxidative stress and this increased expression was associated with increased mineralisation [100-102] den Uyl et al Arthritis Research ... atherosclerosis and osteoporosis An increased IMT has been associated with severity of atherosclerosis and increased cardiovascular risk and considered useful in identifying subjects with increased risk ... osteoporosis and specific categories of CV disease Links between CV disease and osteoporosis Common pathogenesis CV disease is preceded by atherosclerosis, for example, arterial disease Atherosclerosis...
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Báo cáo y học: "Seropositivity is associated with insulin resistance in patients with early inflammatory polyarthritis: results from the Norfolk" pot
... (IP) and is particularly associated with seropositive disease [1-4] Insulin resistance (IR) is known to be increased in patients with established RA [5,6] and has been shown to be a risk factor for ... insulin resistance; IP: inflammatory polyarthritis; IQR: interquartile range; NOAR: norfolk arthritis register; RA: rheumatoid arthritis; RF: rheumatoid factor; TNF: tumour necrosis factor; VAS: visual ... (CVD) is the leading cause of death in patients with inflammatory polyarthritis (IP) especially in seropositive disease In established RA, insulin resistance (IR) is increased and associated with...
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Báo cáo khoa học: "Occult hypoperfusion is associated with increased mortality in hemodynamically stable, high-risk, surgical patients" pdf
... same group of investigators in trauma patients have shown that persistent occult hypoperfusion is associated with increased morbi-mortality, and early correction seems to improve outcome [7,8,16] ... predictors of mortality and morbidity Am J Surg 2003, 185:485-491 McNelis J, Marini CP, Jurkiewicz A, Szomstein S, Simms HH, Ritter G, Nathan IM: Prolonged lactate clearance is associated with increased ... (e.g pancreatitis, peritonitis); and previous disease of a vital organ, defined as compensated or prior congestive cardiac failure, previous clinical indication of ischemic heart disease (previous...
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Báo cáo y học: "The risk for bloodstream infections is associated with increased parenteral caloric intake in patients receiving parenteral nutrition" pdf
... attributed to TPN -associated hyperglycemia [10,17] This risk is not restricted to surgical patients Patients receiving stem cell transplantation have an increased infection risk with TPN -associated ... admission diagnosis was not associated with an increased risk for BSI Diagnosis of BSI was a median of 7.5 days (3–14 days) after initiation of TPN As expected, ICU admission was an important risk ... consisted primarily of long- chain triglycerides Lipids were infused separately and limited to 12 hours each night, in order to reduce the known risk of proliferation of pathogenic organisms within...
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Báo cáo y học: "Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries" potx
... of storage in this study population References • Mortality at 30 days was increased with to units of RBCs of 28 or more days of storage in this study population • This is the first study to specifically ... and increased risk of sepsis independently associated with old RBCs will also increase these risks [25,27,35-38] We theorize that the hyper-inflammatory and hypercoagulable state associated with ... indicates that patients with type A blood have increased concentrations of factor VIII and von Willebrand's factor, which was associated with increased risk of DVT [40] In our analysis, although there...
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Báo cáo y học: "High serum cortisol level is associated with increased risk of delirium after coronary artery bypass graft surgery: a prospective cohort study" pps
... serum cortisol level was associated with significantly increased risk of postoperative delirium in this risk-adjusted analysis (odds ratio [OR] 3.091, 95% confidence interval [CI] 1.763 to 5.418; ... graft surgery • High serum cortisol level was associated with increased risk of postoperative delirium Whether this relationship is causal or due to other confounders is still unclear • Patients ... delirious symptoms, but it is also possible that hypercortisolemia merely reflects the stress associated with delirium [62] Therefore, further study is needed to illuminate the mechanisms by which...
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báo cáo khoa học: " Resistance to Plasmopara viticola in a grapevine segregating population is associated with stilbenoid accumulation and with specific host transcriptional responses" doc
... individuals to be distributed in nine classes ranging from total resistance to total susceptibility (Additional file 1) The parents in all three years, one confirmed to be partially resistant (M) ... latter group whose resistance could be ascribed to a different mechanism which does not involve the presence of viniferins Interestingly, with respect to both resistance trait distribution and stilbene ... proliferation is swiftly blocked by a combination of constitutive and post-infection resistance mechanisms [6,7] Indeed, resistant Vitis species may benefit from a higher level of constitutive resistance...
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Báo cáo y học: " Off hour admission to an intensivist-led ICU is not associated with increased mortality" pps
... the organisational model with intensivists present during the day and residents supervised by intensivist during off hours is adequate enough to avoid a 'quality gap' during off hours This study ... (0.63 to 0.84) 0.80 (0.64 to 0.99) SMR SAPS II 0.78 (0.67 to 0.90) 0.80 (0.64 to 1.00) SMR APACHE II 0.66 (0.56 to 0.79) 0.71 (0.58 to 0.85) SMR SAPS II 0.69 (0.58 to 0.82) 0.70 (0.58 to 0.85) ... Admission type 14.8 0.001 Admission type (1) 0.001 0.969 0.995 (0.772 to 1.283) Admission type (2) 9.15 0.002 1.377 (1.119 to 1.695) Off hours admission 1.89 0.121 1.125 (0.969 to 1.306) Admission...
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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... SF2 is a genuine SG component (Fig 4B) To determine whether other cellular stresses led to the migration of ASF ⁄ SF2 into SGs, COS cells expressing HA-ASF ⁄ SF2 were exposed to cytoplasmic stresses ... pathway is a pre-requisite for ASF ⁄ SF2 migration into SGs upon stress Because both RRMs contributed to ASF ⁄ SF2 cytoplasmic redistribution, we investigated their intrinsic capacity to so by ... determinants and mechanisms of the subcellular distribution of TIAR [5], as well as its capacity to assemble into cytoplasmic stress granules (SGs) [12,13] However, the molecular mechanism by which TIAR...
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Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx
... 7A,B), which is in good agreement with the halflife of HO-1 mRNA determined in HeLa cells [37] Interestingly, the half -life of HO-1 mRNA was prolonged to about h in HeLa cells transfected with siHO-2 ... expression with each of two different siRNAs is consistently associated with increased expression of HO-1 mRNA and protein Moreover, we provide evidence 5340 that at least three mechanisms may ... of HO-1 mRNA In this context, we have reported that maximum induction of HO-1 mRNA expression was detected within h by treatment with cadmium in HeLa cells, which is due to increased transcription...
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Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
... activity This requirement for prolonged treatment of cells to ST to observe desensitization, is in contrast to the rapid inactivation that is seen for other members of the guanylyl cyclase receptors, ... reported to undergo ligand-mediated internalization with a t1/2 of in HEK293 cells [3] Forty to fifty per cent of the internalized receptor is recycled back to the surface and the rest is directed to ... GC-C signaling pathway is modulated in vivo in response to ligand In T84 cells, 18 h ST treatment led to cellular refractoriness to further ST stimulation and this refractoriness was contributed...
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Báo cáo khoa học: A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration pdf
... that the ANT of our mitochondrial preparations of A franciscana embryos is fully functional ANT of A franciscana is refractory to inhibition by BKA As mentioned above, BKA was without an effect on ... failed to inhibit ANT operation as compared with the control (5 mm NH4OH, which is the vehicle of BKA, trace c) With the same BKA stocks, this poison fully inhibited ANT operation in rat liver mitochondria ... from broken mitochondria in the suspension The effect of oligomycin alone is hard to predict, because this inhibitor blocks both ATP formation by polarized mitochondria and ATP hydrolysis by depolarized...
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báo cáo hóa học:" Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival" doc
... regard to cardiovascular risk factors and enrolled 10.902 women[12] The standard surgical management was a total abdominal hysterectomy, bilateral salpingo-oophorectomy and omentectomy with cytological ... should incorporate this in any multivariate analysis While associated with AR expression, neither ER nor PR expression correlated with survival in this study Such findings contrast with Lee et al who ... as a single disease, but rather several distinct entities with different clinical behaviours These entities are in part reflected in histopathological characteristics and therefore, to obtain better...
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báo cáo hóa học:" Reduced renal function is associated with progression to AIDS but not with overall mortality in HIV-infected kenyan adults not initially requiring combination antiretroviral therapy" potx
... models, lower CrCl remained significantly associated with shorter times to developing WHO stage or disease, but was no longer associated with times to developing CD4 counts of less than 200 cells/mm3 ... 5, Model 2) were associated with overall mortality Discussion To our knowledge, the current study is the largest analysis to date investigating the natural progression of HIV disease in sub-Saharan ... 2) at enrolment was associated with lower CrCl, but not with lower eGFR Lower enrolment weight was associated with lower CrCl, but in contrast, lower weight was associated with higher eGFR Of...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25