logarithmic gains measurements of the sensitivity of the model
Báo cáo y học: "The Proteomic Code: a molecular recognition code for proteins" docx
Ngày tải lên :
13/08/2014, 16:21
... target sequences the progression of the residues Synthesis pattern for construction of depending on the and Synthesis pattern for construction of target sequences and the progression of the permutations ... Effects of a single codon residue on the structure of the amino acids Effects of a single codon residue on the structure of the amino acids Page 12 of 44 (page number not for citation purposes) Theoretical ... interactions of complementary segments W-C base pair formation lowers the average free energy, dG, of the RNA and the magnitude of change is proportional to the number of base pair formations Therefore the...
- 44
- 418
- 0
Báo cáo khoa học: A novel plant protein disulfide isomerase family homologous to animal P5 – molecular cloning and characterization as a functional protein for folding of soybean seed-storage proteins docx
Ngày tải lên :
30/03/2014, 04:20
... (supplementary Fig S4) Nucleotide sequence of the ORF of the GmPDIM gene was identical to that of the cDNA Comparison of the soybean genomic sequence of GmPDIM with those of A thaliana (AGI number At1g04980 ... with either protease The sites of proteolytic cleavage were determined to be Lys150 (K150) and R255 by N-terminal sequencing of the trypsin peptide fragments The N-terminal sequences of other fragments ... facilitate the escape’ of the cystein residue of the active site from a mixed disulfide bond with substrate [5,23], were also conserved The amino acid sequence of GmPDIM and orthologs from other plant...
- 12
- 348
- 0
Báo cáo hóa học: "Reference values and physiological characterization of a specific isolated pig kidney perfusion model" doc
Ngày tải lên :
20/06/2014, 00:20
... examine the creatinine clearance used as approximation of the glomerular filtration rate (GFR) The creatinine clearance represents the mathematical product of the U/Pcrea quotient and the urine-flow ... qualify the outcome of the isolated kidney In this respect, considering the nephron's handling of substrates, the tubular reabsorption of sodium is a further prominent mechanism and the fractional ... conditions via the cannulated external jugular vein Organ collecting The pigs of the slaughterhouse groups were electrically stunned and then exsanguinated Then the organs were Page of 13 (page...
- 13
- 548
- 0
Báo cáo hóa học: " Design and Characterization of a 5.2 GHz/2.4 GHz ΣΔ Fractional-N Frequency Synthesizer for Low-Phase Noise Performance" potx
Ngày tải lên :
22/06/2014, 22:20
... Each of the three loops is identical The input of the second loop is taken from the quantized error Eq1 of the first loop, while the input of the third loop is taken from the quantized error Eq2 of ... between these two curves at an offset frequency of 200 kHz Therefore the best possible out -of- band phase noise is the raw phase noise of the VCO and the inband phase noise will be dominated by the ... the frequency at which the synthesizer is operating In this form, phase noise has the units of [rad2 /Hz] Often this is quoted as so many dB down from the carrier in units of [dBc/Hz] To further...
- 11
- 416
- 0
Báo cáo khoa học: A strategy for the generation of specific human antibodies by directed evolution and phage display An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom docx
Ngày tải lên :
23/03/2014, 13:20
... C noxius venom To the best of our knowledge, this is the first report of the generation of a human recombinant antibody fragment capable of neutralizing the toxic effects of the whole venom from ... of mouse weight) [13] Clone 3F was matured by three cycles of directed evolution The use of a set of stringent conditions in the third cycle allowed the selection of several improved clones The ... One of these changes occurred at framework of the heavy chain (Asp74Asn) and of the light chain Two of the changes (Thr152Ile and Ser197Gly) occurred at frameworks and 3, respectively, and the...
- 11
- 679
- 0
Báo cáo hóa học: " Nucleotide mismatches between the VP7 gene and the primer are associated with genotyping failure of a specific lineage from G1 rotavirus strains" potx
Ngày tải lên :
20/06/2014, 01:20
... was reported that the accumulation of point mutations in VP4 and VP7 genes was the main cause of the failure of the G or P-typing of rotavirus strains [7,8,12,16-21] At least, there are four multiplex ... out of 121 G1 strains from lineage I showed the four specific mismatches at the 5' end of the 9T1-1 primer This was associated with the failure of genotyping of G1 strains from Bangladesh Two of ... ❍; three out of the four mutations by ■, and three mutations plus others at the primer binding site by ᮀ The open branches indicate one or two mutations at the primer binding site The lineages...
- 4
- 329
- 0
Báo cáo y học: "Validation of a specific measure to assess healthrelated quality of life in patients with schizophrenia and bipolar disorder: the ‘Tolerability and quality of life’ (TOOL) questionnaire" doc
Ngày tải lên :
09/08/2014, 01:21
... in these multidimensional scales we used the unweighted scores In both cases, the higher the scores, the better the HRQoL, and vice versa (2) The Spanish version of the TOOL questionnaire The ... from the report from the Chair of the Outcomes Reference Group Leeds, UK: National Institute of Mental Health in England; 2005 Thornicroft G, Tansella M: Growing recognition of the importance of ... guided by the estimation of the utility function according to which a large number of patients is needed to maximise the precision and reduce the risk of measurement error To this end, in the present...
- 8
- 476
- 0
Báo cáo y học: "Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis" ppt
Ngày tải lên :
09/08/2014, 01:23
... significant at the 5% level In factorial regression, there also was a correlation of the SE with the Ratingen score (P = 0.044) The presence or absence of the SE explained 29% of the variance of the Ratingen ... of the inheritable factors of RA has largely focused on components of the immune system, such as the SE and the cytokine network [1,2,30] In the cohort investigated here, the association of the ... damage The 1G-5A haplotype explained the variability of the Ratingen score in the same order of magnitude as the SE Our data suggest that this association is phasic The possession of the 1G-5A...
- 9
- 357
- 0
Báo cáo y học: "The identification and characterization of a novel protein, c19orf10, in the synovium" docx
Ngày tải lên :
09/08/2014, 10:20
... area of the putative signal peptide were poorly conserved although the majority of the residues were non-polar The remainder of the protein showed a high degree of conservation between the human ... sequence of c19orf10 (a) The chromosomal localization of the region containing the c19orf10 c19orf10 gene is indicated on the ideogram The area containing the c19orf10 gene is expanded and the base-pair ... Research & Therapy Vol No Weiler et al endothelium displays an increased ratio of apoptotic to proliferative cells, which is indicative of vascular remodeling [3] These changes may contribute to the...
- 9
- 489
- 0
báo cáo khoa học: "Design and characterization of protein-quercetin bioactive nanoparticles" doc
Ngày tải lên :
11/08/2014, 00:23
... DLS measurements of the BSA system The concentration of BSA was 1.5 × 10-5 mol/L (A) ACF of BSA vs the concentration of DMSO; (A’) Size distribution histogram of BSA vs the concentration of DMSO; ... DLS measurements of the Lys system The concentration of Lys was 1.5 × 10-5 mol/L (A) ACF of Lys vs the concentration of DMSO; (A’) Size distribution histogram of Lys vs the concentration of DMSO; ... Figure DLS measurements of the Mb system The concentration of Mb was 1.5 × 10-5 mol/L (A) ACF of Mb vs the concentration of DMSO; (A’) Size distribution histogram of Mb vs the concentration of DMSO;...
- 14
- 290
- 0
Design and characterization of functional novel oligopeptides
Ngày tải lên :
04/10/2015, 10:25
... Three of the peptides synthesized consist of alternating hydrophobic and hydrophilic residues Out of these three peptides, two of them consist of a cell adhesion motif ‘RGD’ in the middle of the ... complete automation of the entire synthesis is possible At the same time, some of the potential disadvantages of the stepwise SPPS involve incomplete reactions and the gradual buildup of insoluble by-products ... with an overall neutral charge have the ability to form fiber-like structure In the last section of the thesis, the role of the peptides on the nucleation of CaCO3 crystals was studied All peptides...
- 95
- 274
- 0
Design and characterization of interposers for high speed fine pitch wafer level packaged device testing
Ngày tải lên :
04/10/2015, 10:25
... contributing to the signal degradation is the design of the printed circuit board (PCB) part of the interposer 75 % of the loss of the overall test system is attributed to this board viii List of Figures ... 4.7: Cross sectional view of the interposer showing the thickness of the layers and the composition of the materials used 63 Figure 4.8: Top view showing the layout of the proposed elastomer interposer ... governed by the number of probes in the array and their proximity to each other Varying the width of the blade shank increases or decreases the surface area where the blade is attached to the probe...
- 126
- 202
- 0
Tài liệu Báo cáo khoa học: Characterization of a chemosensory protein (ASP3c) from honeybee (Apis mellifera L.) as a brood pheromone carrier pdf
Ngày tải lên :
21/02/2014, 03:20
... equivalent (Qeq), the average amount of pheromone found in the gland of mated queen [50] The synthetic pheromone blend was dissolved in ethanol to a final concentration of 10 mgÆmL)1 Other competitor ... frame encodes a 130-amino acid polypeptide The comparison of the amino acid sequence deduced from the cDNA sequence with that of the N-terminal sequence of the natural ASP3c protein [20] showed that ... reported for other CSPs The deduced amino acid sequence of ASP3c compared with those of other insect CSPs and related proteins clearly identified ASP3c as a member of the CSP family (Fig 2) The honeybee...
- 11
- 642
- 0
Báo cáo khoa học: Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage potx
Ngày tải lên :
30/03/2014, 04:20
... Substitution of the H2AX Ser129 by Ala restored the ability of the pph3D strain to turn off checkpoint signalling in a timely manner and re-enter the cell cycle after DNA repair of the double-strand ... [9] One of the earliest events in the cellular response to many DNA-damaging agents is the phosphorylation of histone 2AX (H2AX) at Ser129 in its C-terminal tail and the accumulation of the phosphorylated ... amounts of cH2AX generated in the presence of increasing doses of MMS (Fig 3C) and even with the low levels of cH2AX that were sometimes present in yeast cell lysates in the absence of DNA-damaging...
- 11
- 362
- 0
Báo cáo khoa học: Proteome analysis of a rat liver nuclear insoluble protein fraction and localization of a novel protein, ISP36, to compartments in the interchromatin space pptx
Ngày tải lên :
30/03/2014, 20:20
... underneath the inner nuclear membrane and function to maintain the nuclear architecture [3] The majority of vimentin may be bound to the nuclear lamina from the outside the nucleus [18] The presence of ... from the interchromatin region and found in the periphery of condensed chromosomes (Fig 9, panels and 7) Some of the ISP36 did not diffuse into the cytoplasm and remained near the chromosomes These ... such that the color became yellow (Fig 8) These results confirmed the presence of ISP36 in compartments in the interchromatin space To precisely examine the localization of ISP36 in the cell cycle,...
- 12
- 400
- 0
Knowledge transfer in Tehran University of Medical Sciences: an academic example of a developing country pdf
Ngày tải lên :
11/08/2014, 05:21
... Priorities of the professoriate New York, The Carnegie Foundation for the Advancement of Teaching; 1990 Glassick CE, Huber MT, Maeroff GI: Scholarship assessed: Evaluation of the professoriate ... of the total score The maximum score attainable in the active strategies was six and the mean score of the researchers' performance in these strategies was 0.54 (SD = 1.02), which consisted of ... 9% of the total score Table and show the results of a linear regression analysis with the 'Enter' method As shown in tables and 4, the dependent variables in these regressions are the scores of...
- 8
- 341
- 0
báo cáo khoa học: " Knowledge transfer in Tehran University of Medical Sciences: an academic example of a developing country" pot
Ngày tải lên :
11/08/2014, 16:21
... Priorities of the professoriate New York, The Carnegie Foundation for the Advancement of Teaching; 1990 Glassick CE, Huber MT, Maeroff GI: Scholarship assessed: Evaluation of the professoriate ... of the total score The maximum score attainable in the active strategies was six and the mean score of the researchers' performance in these strategies was 0.54 (SD = 1.02), which consisted of ... 9% of the total score Table and show the results of a linear regression analysis with the 'Enter' method As shown in tables and 4, the dependent variables in these regressions are the scores of...
- 8
- 315
- 0
Magnetic resonance spectroscopy correlation with histological analysis in gliomas and structure determination of a hypothetical protein
Ngày tải lên :
10/11/2015, 11:35
... for many weeks The inherent low sensitivity of the technique requires protein concentrations of about 1mM Due to the large number of protons in a protein, to reduce the problem of peak overlap ... shifts of metabolites With the chemical shift database of metabolites and the correlations between protons provided by the COSY spectrum, almost all of the metabolites shown in the HSQC spectrum of ... detect and diagnose type of brain diseases at the beginning The more efficient and accurate the diagnosis is made, the higher the possibility for the patient to be cured Therefore it is significant...
- 92
- 284
- 0
Báo cáo khóa học: Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus A member of a novel protein family related to protein disulfide-isomerase doc
Ngày tải lên :
16/03/2014, 16:20
... the presence of the nucleotide These experiments indicate that the binding and/or hydrolysis of ATP not have any effect on the conformation of PfPDO, possibly because of the localization of the ... is far away from the redox active sites in the sequence Furthermore, the measurements of the rates of PDI-catalysed refolding of scrambled RNase A, in the absence or presence of ATP, show that ... using PDI However, the temperature of the assay, which is limited by the stability of the protein substrate RNase, is very far from the optimal growth temperature of the hyperthermopilic micro-organism...
- 12
- 506
- 0