localization of transmitter candidates in the hippocampal region

... specific labelling of ACh in the pools after infiltration of labelled choline into the cerebral cortex (Chakrin and Whittaker, 1969) constitutes proof that the pools exist in vivo The binding of ACh ... of cholinergic cell bodies or nerve terminals in a certain region (Table I) The main part of ChAc from the hippocampus and caudate nucleus is obtained in particulate form indicating that in these ... supply of choline, and hence the choline for ACh-synthesis, in a lipid-bound form from the blood In some preliminary studies, the uptake of [Me-’4C]choline into the subcellular fractions of brain...

Ngày tải lên: 29/03/2014, 13:20

... selectivity of the palytoxin-induced pore Assuming that palytoxin might induce cation-permeable pores in the apical membrane, the Isc evoked by the toxin should consist of an in ux of Na+, the prevalent ... we were interested in investigating the interactions of the toxin with the H+/K+-ATPase from rat colon The experiments were carried out in an Ussing chamber, which, compared to the single-cell ... paradigm, has the advantage of allowing one to asses at any time of the measurement either the apical or the basolateral surfaces of the epithelial cell membrane Administration of palytoxin on the apical...

Ngày tải lên: 17/03/2014, 11:20

... limited number of cytokines that inhibit the adhesiveness, growth and migration of cancer cells The most intriguing finding of the present study was that the function of MDA-7 in prostate cancer ... is linked to the invasiveness of prostate cancer cells [12] and participates in the regulation of the interactions between prostate cancer cells and endothelial cells, the later involving the ... sec which resulted in complete death of the cells over the electrode The migration of healthy cells from the edge of the wounding to the wounding space was tracked Similar to the changes seen with...

Ngày tải lên: 18/06/2014, 19:20

... limited number of cytokines that inhibit the adhesiveness, growth and migration of cancer cells The most intriguing finding of the present study was that the function of MDA-7 in prostate cancer ... is linked to the invasiveness of prostate cancer cells [12] and participates in the regulation of the interactions between prostate cancer cells and endothelial cells, the later involving the ... sec which resulted in complete death of the cells over the electrode The migration of healthy cells from the edge of the wounding to the wounding space was tracked Similar to the changes seen with...

Ngày tải lên: 20/06/2014, 03:20

... anti-inflammatory action of statins in RA The combined effects of DAF, at the level of C3 and C5 convertases, and of CD59 inhibiting the terminal attack complex has the potential to exert antiinflammatory ... respectively Furthermore, the failure of squalene to influence the response suggested that the mechanism underlying the actions of the statins was cholesterol independent Although the effect of statins on ... complement-mediated injury [18] DAF and MCP act at the level of the C3 convertase In contrast, CD59 inhibits the terminal pathway of complement activation, preventing the incorporation of C9 into the MAC...

Ngày tải lên: 09/08/2014, 08:22

... indicated by CSAD- and taurine-positive cells We found the presence of taurine-containing cells and taurine-induced acid secretion in the stomach In the body of the stomach, taurine-immunoreactive cells ... during oxidation Taurine-containing cells are present in the myenteric plexus and submucosal plexus of the enteric nervous system in the stomach Taurinergic neurons in the muscle layer of the ... various doses of taurine and acid secretion Values are the mean ± SEM (n = 6) increases the level of cAMP Fourth, the presence of taurine-containing cells in the rat stomach is confirmed, as indicated...

Ngày tải lên: 10/08/2014, 05:21

... explaining the purpose of the study to the prospective respondent General 33 instructions on completing the questionnaire and the importance of completing all questions were included The covering ... organization considering the costs of leaving In continuance commitment, the employees consider the disadvantages of leaving the organization and avoid quitting Continuance commitment also includes factors ... object to another, it is a measure of the 19 employees‟ willingness to remain with a firm in the future It often reflects the employees‟ belief in the mission and goals of the firm, willingness to...

Ngày tải lên: 22/10/2015, 13:43

... as in clinical trials,7–10 to evaluate the equivalence of the two case-control studies in assessing the risk of cancer deaths due to smoking We first defined a range of equivalence as an interval ... prevalence of smoking between male living spouses of women who died of any cause and those spouses of women who died of some other causes other than smoking related causes The prevalence of smoking ... uncertain of the age when smoking began A validity study in Shanghai was conducted where the surviving spouse was the informant and both husband and wife had reported their smoking habits in the...

Ngày tải lên: 26/10/2012, 09:48

... Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Spring Rice – 2009 ( Quinal/ha) Number of paricals/m2 Number of grain/pan 1A 1B 12 LS DO5 % of umfiiied ... DO5 Number of grain/pan % of umfiiied grain 1000 grain weight(g) Grain yield Tab 6: Effect of KNO3 Spraying on rice yield on degraded Soie in Bac Giang 2009 ( Quinal/ha) Treat Spring Rice Summer ... umfiiied grain 1000 grain weight(g) Grain yield Tab 5: Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Summer rice – 2009 ( Quinal/ha) Number of paricals/m2...

Ngày tải lên: 20/01/2014, 02:20

... difficulty in understanding these concepts, which may have resulted in inconsistent responses We found inconsistencies in 12.2% of the sample, indicating the difficulties in communicating the information ... influence in their life Nine point seven percent of the participants were classified into the group with "high religiosity" There were no Muslim, Hindu or Buddhist participants The majority of ... among the study sites, but the data from the pilot project were not The following is an outline of the questionnaire: the first page was an informed consent form to participate in the study The...

Ngày tải lên: 13/02/2014, 06:20

... chromium was located in the middle of the specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority of the chromium was present in the form of Cr(VI) and this ... in the glacial till As a result of this, the electro-osmotic flow in contaminated kaolin is higher than that observed in the contaminated glacial till The potable water initially introduced into ... velocity of 0.013 cmyh for kaolin and 0.03 cmyh for glacial till Thus, the electro-osmotic flow is slightly influenced by the soil type and the presence of the contaminants, including the form of chromium...

Ngày tải lên: 16/03/2014, 00:07

... chromium was located in the middle of the specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority of the chromium was present in the form of Cr(VI) and this ... in the glacial till As a result of this, the electro-osmotic flow in contaminated kaolin is higher than that observed in the contaminated glacial till The potable water initially introduced into ... velocity of 0.013 cmyh for kaolin and 0.03 cmyh for glacial till Thus, the electro-osmotic flow is slightly influenced by the soil type and the presence of the contaminants, including the form of chromium...

Ngày tải lên: 16/03/2014, 00:07

... chromium was located in the middle of the specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority of the chromium was present in the form of Cr(VI) and this ... in the glacial till As a result of this, the electro-osmotic flow in contaminated kaolin is higher than that observed in the contaminated glacial till The potable water initially introduced into ... velocity of 0.013 cmyh for kaolin and 0.03 cmyh for glacial till Thus, the electro-osmotic flow is slightly influenced by the soil type and the presence of the contaminants, including the form of chromium...

Ngày tải lên: 16/03/2014, 00:07

... in the baseline health status reached minimal clinical significance, and may have influenced the changes in health status However, except for the baseline score of the Symptoms in the SGRQ, the ... total score of the CRQ Following the baseline scores, the frequency of exacerbations significantly accounted for the changes in the Mastery of the CRQ (R2 = 0.03) and the Symptoms of the SGRQ (R2 ... baseline were observed in two domains (Dyspnea and Emotion), the total scores of the CRQ and in the Activity scores of the SGRQ In subjects with exacerbations, statistically significant declines in...

Ngày tải lên: 18/06/2014, 19:20

... in the baseline health status reached minimal clinical significance, and may have influenced the changes in health status However, except for the baseline score of the Symptoms in the SGRQ, the ... total score of the CRQ Following the baseline scores, the frequency of exacerbations significantly accounted for the changes in the Mastery of the CRQ (R2 = 0.03) and the Symptoms of the SGRQ (R2 ... baseline were observed in two domains (Dyspnea and Emotion), the total scores of the CRQ and in the Activity scores of the SGRQ In subjects with exacerbations, statistically significant declines in...

Ngày tải lên: 20/06/2014, 16:20

... mg/kg/day of acrylamide showed histopathological changes in the seminiferous tubules (Fig 5B) There were thickening and multiple layering of the tubular endothelium, degeneration of germ cells, and the ... formation of many multinucleated giant cells (arrow heads) in seminiferous tubules H & E stain, ×50 and multiple layering of the tubular endothelium, degeneration of germ cells, and the formation of ... mM of acrylamide significantly increased the frequencies of chromosomal aberration in the presence or absence of S9 mixture Moreover, the cells treated with 10 or 50 mM of acrylamide further increased...

Ngày tải lên: 07/08/2014, 18:21

... targets of anti-TNF-α activity in RA, and may provide an insight into a new and interesting mechanism of action of anti-TNF-α mAbs in the control of inflammatory arthritis Competing interests The ... neutrophils were mixed in ml polystyrene vials with × 10-5 mol/l lucigenin in a final volume of 700 µl The vials were placed in the Luminometer 1251 (LKB Wallace, Turku, Finland) in the dark and allowed ... phagocytic cells and the involvement of these cells in the host defence against infections suggest that impairment in phagocytic cell activity may heighten the risk for infection during TNF-α neutralization...

Ngày tải lên: 09/08/2014, 06:22

... peptide (AP9) on the invasive ability of the co-culture cells (a) The haematoxylin and eosin staining results of the cells lower surface filters show that the cells had invaded through the filter and ... showed positive expression of TIMP-1 in the lining and the sublining layers The expression of CD147 correlated significantly with that of MMP-1 (p < 0.05), but the expression of CD147 and MMP-1 did ... metalloproteinase-1 (RA MMP-1), tissue inhibitor of metalloproteinases-1 (RA TIMP-1) and blank contrast (RA blank) in the lining and sublining layers in RA synovium (× 400) The bottom two images show the...

Ngày tải lên: 09/08/2014, 06:23

... the role of CYC in the care of these patients In our meta-analysis, two of the three greatest mean differences of the FVC after 12 months of therapy were achieved in observational studies using ... difference in the meta-analysis The overall pooled analysis included the mean changes of the FVC and the DLCO after 12 months of therapy obtained from the observational studies and from the CYC ... within the range of those reported in the literature altered the results Adverse events We evaluated the relative risk of having adverse events in the CYC group compared with the control groups in...

Ngày tải lên: 09/08/2014, 13:22

... flow into a collecting circuit filled with heparinized saline (4 U/ml of saline) positioned 54 cm above the rat The temperature of the blood in the syringe was maintained at 37- 37.5°C The aortic ... recovery of hind limb function The placing/stepping reflex (SPR) was assessed by dragging the dorsum of the hind paw along the edge of a surface This normally evokes a coordinating lifting and placing ... responses of the spinal cord in IRI but also its clinical neurological impacts [14] Interruption of aortic blood flow in IRI may not only induce spinal cord injury, but also induce injury of the heart,...

Ngày tải lên: 10/08/2014, 05:21