local treatment issues in women with hereditary breast cancer

... maintenance therapy for patients with metastatic breast cancer in complete remission following induction treatment J Clin Oncol 1998; 16 (5): 1669-1676 French Epirubicinn Study Group Epirubicin-based ... breast cancer during first-line paclitaxel chemotherapy Anticancer Res 2003; 23(2C): 1939-42 Nomura Y Different survival determinants of metastatic breast cancer patients treated with endocrine ... sites (single versus multiple); type of first-line chemotherapy (anthracycline- and/or taxane-containing regimen versus other); previous line of hormonotherapy administered in metastatic setting...

Ngày tải lên: 08/08/2014, 17:20

... formal paraffin section remain widespread In this study, we describe our experience of routine intraoperative frozen section of sentinel nodes in women with invasive breast cancer but without overt ... surgical technique Consecutive, consenting, clinically node negative women with unifocal, invasive breast cancer undergoing surgical treatment for invasive breast cancer between December 2004 and December ... dissection with all resected tissue being sent for standard pathological processing and review Any remaining sentinel nodal tissue after frozen sectioning were fixed in formalin and embedded in paraffin...

Ngày tải lên: 09/08/2014, 07:21

... examining adjuvant radiotherapy in DCIS for patients with breast cancer: ipsilateral invasive breast cancer recurMeta-analysis examining adjuvant radiotherapy in DCIS for patients with breast cancer: ... examining adjuvant radiotherapy in DCIS for patients with breast cancer: ipsilateral DCIS breast cancer recurMeta-analysis examining adjuvant radiotherapy in DCIS for patients with breast cancer: ... examining adjuvant radiotherapy in DCIS for patients with breast cancer: contralateral breast cancer recurrence Meta-analysis examining adjuvant radiotherapy in DCIS for patients with breast cancer: ...

Ngày tải lên: 09/08/2014, 10:21

... of women The finding that women with cervical cancer experienced a greater improvement than women with endometrial cancer and women who had received radical hysterectomy faired better than women ... depressed women at baseline who especially improved on this measure with the PED Increasingly, the importance of combining quantitative with qualitative methods is being encouraged in women s sexuality ... effective in women with sexual complaints following treatment for early-stage gynaecologic cancer, and raise opportunities for adapting the PED to other subgroups of women such as women with more...

Ngày tải lên: 22/03/2014, 10:20

... having primary or less education Physical scores increase as the education level increases in the women Women who had monthly income

Ngày tải lên: 28/03/2014, 14:20

... surfaces (e.g., skin, lining of the intestine) against bacteria, and plays a critical role in chronic intestinal inflammation [24,25] The unchanged IL-17 and IL-23 levels in CFS noted in this study ... fundamental evaluation tool in Clinical Medicine Clin Chem 1993, 39:561-577 Waldmann TA: The biology of interleukin-2 and interleukin15: implications for cancer therapy and vaccine design Nature Rev ... patients in other studies had elevated TNFα [15,17] Interleukin-13, associated with inhibitory effects on inflammatory cytokine production, was lower in cases compared to controls The anti-inflammatory...

Ngày tải lên: 18/06/2014, 15:20

... and/ or improved time to relapse when administered in the adjuvant setting in women with Her2-expressing breast cancer as a single agent or in combination with chemotherapy [3-7] However, trastuzumab ... stimulating factor (GM-CSF) and interleukin (IL)-2 in eight patients with metastatic breast carcinoma overexpressing Her2 All but one patient received concomitant trastuzumab treatment during the ... the first amino acid in the Her2 protein) were in computer modelling predicted to bind multiple human leukocyte antigen (HLA)-DR molecules and indeed found to exhibit high-affinity binding to a...

Ngày tải lên: 18/06/2014, 16:20

... role in the intra-ovarian mechanisms regulating the ovarian function In fact, significant changes in serum AMH levels in PCOS patients ovulating under metformin, such as in those remaining anovulatory ... cells to FSH determining an higher number of follicles and a major ovarian volume [15-17] Metformin, an insulin-sensitizing drugs recently introduced for the treatment of women with PCOS, has been ... globulin (SHBG)], and metabolic evaluation, including evaluation of fasting glucose and insulin levels Insulin resistance was evaluated using the homeostasis model analysis (HOMA) [fasting glucose...

Ngày tải lên: 20/06/2014, 07:20

... Glucose-to-insulin ratio rather than sex hormone-binding globulin and adiponectin levels is the best predictor of insulin resistance in nonobese women with polycystic ovary syndrome J Clin Endocrinol ... trimester insulin resistance and subsequent pre-eclampsia In fact, insulin resistance, in concert with other contributing factors, including hyperandrogenism [27], inflammation [28] and increased ... between insulin resistance and subsequent pre-eclampsia In particular, two prospective studies [23,24] showed an increased risk of pre-eclampsia in women with impaired insulin resistance during the...

Ngày tải lên: 20/06/2014, 07:20

... confirming that there is endothelial dysfunction in women with PCOS in comparison with normal subjects The pathophysiological mechanism of inducing endothelial dysfunction remains unclear, but insulin ... Sahin T, Duman C: Endothelial dysfunction in young women with polycystic ovary syndrome: relationship with insulin resistance and low-grade chronic inflammation Journal of Clinical Endocrinology ... low-density lipoprotein (LDL) Insulin resistance (IR) was assessed using both fasting insulin levels and the homeostasis model assessment (HOMA) calculation: fasting serum insulin (micro units per millilitre)...

Ngày tải lên: 20/06/2014, 08:20

... irrespective of including or excluding cases of FMS, there were no significant differences in age between those women with and those women without paraproteins within the group of women with CTD but ... γ-globulin and immunoglobulin levels in women with silicone implants compared with those in women without implants are thus at variance with these earlier observations Since all serum globulin fractions ... when only women from Groups and were compared Within the group of women with silicone implants and CTD (Group 1), between those women with paraproteins and those women without paraproteins there...

Ngày tải lên: 09/08/2014, 10:21

... to HIV-infected women without lipodystrophy We and others have reported similar findings among other HIV-infected populations [8,25] Despite its increasing prevalence, HIV disease remains a social ... regarding their body and reduction in their body image related quality of life as compared to HIV-infected women without lipodystrophic changes However, by ascertaining lipodystrophy presence in ... quantifying how persons' body image experiences affect a broad range of life domains, including sense of self, social functioning, sexuality, emotional well-being, eating, exercise, grooming, etc...

Ngày tải lên: 10/08/2014, 05:20

... undertaking this study all researchers were final year podiatry students who had participated in the same training in interview techniques More than one interviewer was involved in generating data ... as those with RA often report frustration with everyday footwear citing difficulties with availability and choice [13], making goals associated with increasing activity unlikely, causing further ... the study Following the initial interview, the interview schedule was further refined (Additional file 1) Generation of data Each interview took place within the out-patient clinic from which...

Ngày tải lên: 10/08/2014, 21:24

... delay (months), morning stiffness (minutes), night pain (number of awakenings) and pain intensity (visual analogue scale (VAS): 0-100 mm, = no pain and 100 = severe pain imaginable) Disease activity ... nondistressed marriage is linked with less pain and better functioning [11] In fact, the associations between spinsterhood and disease progression and severity in RA are complex and interpretation requires ... found that unmarried women had poorer HAQ scores [4,11] However, it has been shown that being married in itself is not associated with better health in RA but that being in a well-adjusted or...

Ngày tải lên: 12/08/2014, 00:20

... J, Crosby RD, Crow SJ, Klein MH, le Grange D, Mitchell JE, Peterson CB, Wonderlich SA: Examining a psychosocial interactive model of binge eating and vomiting in women with bulimia nervosa and ... To be included in the study, a patient had to participate in the investigation in an informed and voluntary way The tenets of the Declaration of Helsinki were followed, and the study gained approval ... because individuals who engage in bingeing and vomiting also manifest problems with social adjustment [48,49] However, our first hypothesis was to correlate the social maladjustment domain with...

Ngày tải lên: 12/08/2014, 01:21

... domain including components of spirituality, acculturation, and interconnectedness; (3) Demographic domain including components of chronological age; and (4) Healthcare System domain including ... specific issues in detail, such as what QOL domains are known to be important for Chinese women Regarding the issue of instrument selection, choosing an instrument for Chinese cervical cancer survivors ... Since the family relationship and kinship play very important roles in daily life in Chinese communities [62], roles and relationship changes due to cancer and treatment greatly influence Chinese...

Ngày tải lên: 12/08/2014, 01:21

... gene with two clusters in a) the extracellular domain (exons 2-4) and b) the serine/threonine protein kinase domain (exons 9-11) Four mutations occurred in more than one independent patient/family: ... species ESEfinder prediction Clinical classification according to family history p.A154G Transmembrane domain Disease causing conserved Not affected IPAH p.E386G Serine/threonine kinase domain Disease ... is in concordance with the results of the French PAH registry [15] Since occurrence of BMPR2 mutations obviously influences the clinical phenotype genetic testing may become of increasing clinical...

Ngày tải lên: 12/08/2014, 13:22

... LBP with or without pain radiating into the leg, who were new to the clinic or had not received chiropractic treatment within the past three months, were invited to participate in the study in ... the groups in relation to type of work, smoking, fee subsidization, leg pain, pain intensity at base-line and at the 4th visit, dura- tion of pain at base-line, total duration of pain in the past ... base-line (duration of pain at base-line, total duration of pain in the past year, and general health), as well as for one previously non-significant variable: pain in other parts of spine in the...

Ngày tải lên: 13/08/2014, 14:20

... examined the timing of muscle activity during PHE in patients with LBP to determine the order in which the muscles are activated during this motor pattern [14-17] To our knowledge, no study has investigated ... was greater in women with LBP than healthy subjects These findings demonstrate an altered activity pattern of the lumbo-pelvic muscles during hip extension in patients with chronic LBP In this study, ... these patients [26] The spinal stabilizing system was primarily described by Panjabi [28], including of subsystems: the spinal column providing intrinsic stability; spinal muscles, Table Electromyographic...

Ngày tải lên: 13/08/2014, 15:21

Ngày tải lên: 29/11/2014, 07:00