... extending our knowledge of membrane trafficking: the order of events involved in assembling protein complexes for endocytosis, the emerging field of clathrin- independent endocytosis, roles for ... 3: PtdIns(3,5)P, is required for delivery of endocytic cargo into the Trang 7 CHAPTER 4: An interaction between the yeast epsin Entl and GTPase activating proteins for Cdc42 is required for cell ... recognition motifs for endocytic machinery to aid in sequestering cargo into sites of endocytosis Coated pit formation Coated pits are sites of vesicle formation, in which clathrin and endocytic
Ngày tải lên: 14/11/2014, 06:20
... for further 48 h For transfection of EGFP-C2-LC3 plasmid, a gift from Dr James Murray (Trinity College Dublin, Dublin), Lipofectamine® 2000 (ThermoFisher Scientific) was used instead The GFP signal ... Silencing of iASPP or autophagy inhibition sensitized choriocarcinoma cell towards oxidative stress Chloroquine, a clinically used lysosomal inhibitor, was also effective in blocking autophagy In ... mediators are involved in determination of p53-induced senescence or apoptosis In contrast, another group showed iASPP silencing reduced p21WAF1/Cip1 expression in keratinocytes and promoted terminal
Ngày tải lên: 17/06/2020, 18:38
Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor - and extracellular matrix-induced signalling events in breast cancer
... observed for stromal αv integrin staining with increasing invasiveness of the tissue types examined (Figure 1B) In contrast, the β1 integrin immunoreactivity detected in the stroma of metastatic ... of IGF and ECM protein interactions on the dissemination and progression of breast cancer in vivo are unclear Given this, we chose to investigate the clinical relevance of proteins required for ... ECM-induced signalling proteins in metastatic breast cancers This study has provided insights into the changing pattern of cellular localisation and expression of IGF- and ECM-induced signalling
Ngày tải lên: 14/10/2020, 15:05
An evaluation of american headway 1 for first year junior college students in electric power university submitted in partial fulfilment of requirements for the degree of master of arts in tesol
... first year junior college students in Electric Power University LIST OF TABLES AND FIGURES Table The Factors that need examining in the materials evaluationprocess Table The detailed information ... \ takes care of people in the hospital takes care of peoples money writes for a newspaper translates things sells things 4flies planes, serves drinks Match a job in A with a line in B Memorize ... M IN IS TR Y OF EDUCATIO N A N D TR A IN IN G HANOI UNIVERSITY NG UYEN TH I BICH NGOC AN EVALUATION OF AMERICAN HEADWAY FOR FIRST YEAR JUNIOR COLLEGE STUDENTS IN ELECTRIC POWER
Ngày tải lên: 02/10/2021, 18:28
Full List of Management Accounting for Decision Makers_17 pot
... information 369 non-financial information 24–5 quality 30 range 30 standards setting 245 see also management accounting: information information systems 21 information technology(IT) 26–7 innovation, ... indicators of performance). The performance for the business as a whole is often given the most weighting, and individual performance the least weighting. Thus, 50 per cent of the bonus may be for corporate ... decentralisation of decision making, this need not necessarily be the case. (b) The benefits of allowing divisional managers autonomy include: l Better use of market information. l Increase in management
Ngày tải lên: 21/06/2014, 10:20
LISTS OF ACCEPTABLE POLYMERS FOR USE IN FOOD PACKAGING APPLICATIONS ppsx
... strong they replaced Kevlar for use in bullet proof vests Large sheets of it can be used instead of ice for skating rinks Food Packaging Materials Polyethylene is vinyl polymer, made from the ... OTHERWISE ARISING OUT OF GOODS OR IN CONNECTION WITH THE INFORMATION CONTAINED HEREIN RECYCLING OF PLASTICS MAY NOT BE AVAILABLE EVERYWHERE CHECK TO SEE IF PLASTICS RECYCLING IS AVAILABLE IN YOUR COMMUNITY ... Use of this code indicates that the package in question is made with a resin other than the six listed above, or is made of more than one resin listed above, and used in a multilayer combination
Ngày tải lên: 01/08/2014, 07:20
báo cáo khoa học: "Implementing health research through academic and clinical partnerships: a realistic evaluation of the Collaborations for Leadership in Applied Health Research and Care (CLAHRC)" pot
... sensing and inter- preting new evidence, integrating it wi th existing evi- dence; reinforcement (or not) by p rofessional networks, which in turn is mediated by local context [23], includ- ing ... standing tradition of including ‘insiders’ [78,79]. An insider perspective will provide insight and enable us to crosscheck face validity of data against the experience of operating within a ... provide information with which to further contextualise findings, provide insight into influences of implementation, and help explanation building. Evaluation team reflection and monitoring Including
Ngày tải lên: 10/08/2014, 11:20
List of Transition Words for Essays pot
... (that) for the purpose of with this intention with this in mind in the hope that to the end that for fear that in order to seeing / being that in view of If then unless when whenever since while ... speaking in the final analysis all things considered as shown above in the long run given these points as has been noted in a word for the most part after all in fact in summary in conclusion in ... They join individual words, phrases, and independent clauses Whereas coordinating conjunctions join parts of a 'sentence', the purpose of transitional words. .. since then before hence since
Ngày tải lên: 10/08/2014, 20:20
Báo cáo y học: " Assessing medically unexplained symptoms: evaluation of a shortened version of the SOMS for use in primary care" doc
... specificity for this cut-off on the 29 symptoms list as well as for the full list. The ROC curve for the FCSE yielded the cut-offs of 6 symptoms for women and 4 for men, but different cut-off for self-report, ... strictly instructing the participants to be aware of severity criteria, the common underesti- mation of somatoform symptoms [10] has been rein- forced in our study. Although stability of single ... a kind of umbrella for other (unexplained) symptoms. At FCSE those symptoms turned to unexplained. As reported for false-positives, the clinical interview setting also seemed to interfere in
Ngày tải lên: 11/08/2014, 16:22
Báo cáo sinh học: "A study on the minimum number of loci required for genetic evaluation using a finite locus model" pptx
... solved for a in terms of n,η,σ 2 a and σ 2 d . Next, by substituting the value obtained for a in the first equation we can obtain p in terms of n, η, σ 2 a and σ 2 d , and then by substituting p in ... matrix of coefficients for θ q . Recursive formulae are available to compute the elements of C q [23]. In the absence of inbreeding, the number of dispersion parameters is Number of loci in finite ... to examine the effect of the presence of inbreeding. The parameters of the FLMS used to calculate BP’s for the data gener- ated according to the nine situations described above, are given in Table
Ngày tải lên: 14/08/2014, 13:22
design, synthesis, and characterization of polymeric materials for uses in energy storage applications
... monomer linearly linked to a polymer of a different monomer Graft copolymers result when there is a central polymer chain that has branching points to... monomers into linear polymer chains (Figure ... polymeric. .. structure of the monomer units plays an integral role in determining the physical properties of the polymer, the architecture of the polymer chain can have an equeally important ... propagation of the active chain end with additional monomers causing the chain to increase in length Termination is when the active chain end is quenched, making it unable to grow any longer...
Ngày tải lên: 13/11/2014, 11:13
fluence of au nanoparticles on the properties of tio2 film for use in DSSC
... the explanation of photocurrent damping seen for Au/ TiO2 composite films in the. .. driving force for electron injection into the semiconductor and hole injection into the electrolyte ... for electron injection in TiO2, but these are also the positions occupied first by Au atoms inserted into the composite films. The loss of the injection pathways contributes to the lowering of ... INFLUENCE OF AU NANOPARTICLES ON THE PROPERTIES OF TIO2 FILMS FOR USE IN DYE-SENSITIZED SOLAR CELL HU XIAOPING (M. Eng. CISRI) THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY
Ngày tải lên: 10/09/2015, 15:47
Q4B EVALUATION AND RECOMMENDATION OF PHARMACOPOEIAL TEXTS FOR USE IN THE ICH REGIONS
... sign-off text 4) Additional clarifying information is incorporated by one or more of the PDG pharmacopoeias in their respective information chapters on pharmacopoeial harmonisation Therefore, ... guideline 2.1.5 Step The annex moves to the regional regulatory implementation step 2.2 Annex Contents The Q4B annexes will contain the following information at a minimum information might be incorporated ... Therefore, the revised information chapter on harmonisation from each pharmacopoeia incorporating such information (in draft form where this is available) should accompany the provided documents If any
Ngày tải lên: 04/12/2017, 04:16
Báo cáo khoa học: The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury pdf
... plated in media containing Geneticin to select for cell containing vector DNA (as in Fig. 5A,G). After three weeks, the number of cells was determined by fixing cells and staining with dye. Individual ... protein, (C) SEP70 protein, (D) AG-2 protein and (E) loading controls for squamous and Barrett’s biopsies (ink stain immu- noblot to normalize for protein loading), as indicated. (F) Immunostaining ... concentrations of ethanol (for 6 h), or (D) combination of fixed DCA (500 l M) and increasing concentrations of ethanol for 2 h. Viability was determined as indicated in Experimen- tal procedures using Trypan...
Ngày tải lên: 23/03/2014, 10:21
Tài liệu effective internet presenceted demopoulos’now required for success in business and life doc
... you think you deleted it. For example, the “Internet Wayback Machine” and Google cache contain copies of “deleted” information. “Unlike footprints left in the sand at the beach, our online data ... search engines will index and display some of these comments when people search on your name, adding to your Internet presence. Effective Internet Presence: Now required for success in business ... Presence: Now required for success in business and life Ted Demopoulos 7 This Personal Branding Thing A brand is what prevents something from being a commodity. It’s why I pay more for a cup of Starbucks...
Ngày tải lên: 14/02/2014, 04:20
Tài liệu The Development of the Feeling for Nature in the Middle Ages and Modern Times doc
... pleasure in digging his fields in spring, clearing them of nettles, and levelling the ground thrown up by the moles, in protecting his seedlings from rain and sun, and, later on, in his gay beds of ... the present of earth vanished into the future of Heaven, and the Kingdom of the Infinite arose upon the ruins of the finite.' The beauty of earth was looked upon as an enchantment of the devil; ... suggestive myth of Baldur, god of light and spring, killed by blind Hödur, was the expression of general grief at the passing of beauty. The Edda has a touching picture of the sorrow of Nature, of her...
Ngày tải lên: 21/02/2014, 20:20
Applying online for admission in 2013 docx
... Nursing College 1005974 Carinus Nursing College 1005977 Charlotte Searle Nursing College 1005986 Coronation Nursing College 1005999 Edendale Nursing College 1006016 Frere College of Nursing 1006019 ... following documents: - Form 1PG - the application form - Form 4 - to be completed if a relative of yours attended UCT in the past; (this information is for the purposes of updating the Alumni Office ... N Theatre & Performance HM008DRM02 Y Y Y N N N Master of Arts in Fine Art Fine Art HM010FIN01 N Y N Y N N Master of Fine Art Fine Art HM011FIN01 N N N Y N N Master of Library and Information Science...
Ngày tải lên: 16/03/2014, 05:20
The Practicalities of Using Nevirapine for PMTCT in Under-Resourced Settings ppt
... challenging, particularly for developing countries, because of the duration of treatment and infusion of the injectable form of AZT during labour and delivery. In the Eastern Cape Province, two clinics ... for easy packing and dispensing . Crucial issues that must be borne in mind include the necessity of developing PMTCT doses that can be self-administered, the need to train TBAs, the need for ... No part of this book may be reprinted or reproduced or utilised in any form or by any electronic, mechanical, or other means, including photocopying and recording, or in any information...
Ngày tải lên: 22/03/2014, 18:20
Báo cáo khoa học: Limited proteolysis of Escherichia coli cytidine 5¢-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis potx
... enzyme into its GAT and synthase domains. Our interest in delineating structural aspects of E. coli CTPS led us to examine the susceptibility of CTPS to controlled proteolysis. In preliminary ... (2002) Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-b- D -arabinofuranosyl cytosine in a human T-lym- phoblastic cell line. Int. J. Cancer 98, 616–623. 15. ... hydrolysis of glutamine, but had a value of k cat thatwashalfofthat observed for wild-type CTPS in the absence of GTP. When the concentration of GTP was increased to 1 m M ,thevalue of k act was increased...
Ngày tải lên: 23/03/2014, 17:22
Towards a safer use of the Internet for children in the EU – a parents’ perspective ppt
... obtain such software (18% vs. 13%-14% of the Internet users). Table 8: Use of filtering and monitoring software Using filtering and/or monitoring software Reasons for not using filtering ... know in real life Spending a lot of time online Creating a profile in an online community Using chat rooms Accessing certain websites Downloading/playing music, films, games Using email/instant ... source for information about safe Internet use in a majority of the countries, in half of the countries less than one-third of the parents used it as a source of information: from 23% in Cyprus...
Ngày tải lên: 29/03/2014, 19:20