... http://www.translational-medicine.com/content/7/1/1 Figure Western blotting analysis of survivin protein in oral cancer cell lines Western blotting analysis of survivin protein in oral cancer cell lines Lysates from oral ... Survivin expression in oral cancer cells We previously showed that the survivin mRNA level was elevated in various cancer cell lines, including gastric cancer cells, colon cancer cells, breast cancer ... survivin expression in the protein level In all the oral cancer cell lines examined in the present study, wild type survivin was detected, but not in normal oral mucosal tissue by Western blotting...
Ngày tải lên: 18/06/2014, 15:20
... Quality of life changes and clinical outcomes in thyroid cancer patients undergoing radioiodine remnant ablation (RRA) with recombinant human TSH (rhTSH): a randomized controlled study Clin Endocrinol ... Discussion In recent years, attention has been paid to the effect of treatment on QOL in cancer patients [25] We have previously found as Pacini et al, that the use of rhTSH preserves the QOL of patients ... at the time of the initial treatment resulting in a slightly older cohort than in our study [10,12,16] Also our proportion of pT1 was higher than in Pacini’s study, and we did not include pT1...
Ngày tải lên: 20/06/2014, 15:20
báo cáo hóa học:" Quality of life in colon cancer patients with skin side effects: preliminary results from a monocentric cross sectional study" pot
... aspects of life over time Finally, considering the clinical conditions of patients included in this study (mainly metastatic and cancer) it was not considered feasible in our setting to administer ... relationship and in providing these groups of patients with accurate and truthful information In respect to comparative data of subjects with skin clinical problems, our sample of colon cancer patients ... treatment [16,17] Patients are generally informed about this kind of correlation since the start of the treatment and this awareness should be taken into account in the coping process of patients with...
Ngày tải lên: 20/06/2014, 16:20
báo cáo hóa học:" Species distribution and antimicrobial susceptibility of gram-negative aerobic bacteria in hospitalized cancer patients" pdf
... patients, 33.3% in case of solid-tumor cancer patients) and Klebsiella pneumoniae (27.3% in case of leukemic patients, 47.6% in case of solid-tumor cancer patients) In both leukemic patients and ... Results in table indicated that in both leukemic patients and solid-tumor cancer patients, gram-negative bacteria causing nosocomial UTI were mainly Escherichia coli (39% in case of leukemic patients, ... solid-tumor cancer patients, gram-negative bacteria causing nosocomial RTI were mainly Klebsiella pneumoniae (48.4% in case of leukemic patients, 27.3% in case of solid-tumor cancer patients) Escherichia...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Responsiveness of the EQ-5D in breast cancer patients in their first year after treatment" ppt
... Classifying patients into subgroups Change scores on global health of the EORTC QLQ-C30 were used to identify subgroups of patients In an analysis of the clinical significance of changes in HRQoL, ... and Treatment of Cancer QLQC30: a quality -of- life instrument for use in international clinical trials in oncology J Natl Cancer Inst 1993, 85(5):365-376 Bottomley A, Aaronson NK: International ... quality -of- life measurement in randomized clinical trials in breast cancer – taking stock Journal of the National Cancer Institute 2003, 95(4):263-281 Montazeri A: Health-related quality of life in...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Association between perceived chewing ability and oral health-related quality of life in partially dentate patients" ppt
... both constructs was different in men and women and in two categories of years of schooling, with the male patients and those patients with higher years of schooling having the stronger correlations ... version of the chewing function questionnaire in partially dentate patients BMC Oral Health 2009, 9:9 23 Baba K, Inukai M, John MT: Feasibility of oral health-related quality of life assessment in ... responses were combined, resulting in a to 20 summary score that was called the “chewing function score,” where higher scores indicate better chewing ability Internal consistency of chewing function...
Ngày tải lên: 20/06/2014, 15:20
báo cáo khoa học: "Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients" pot
... high [7] Cancer invasion begins with inflammation around cancer cells Thus, it has been reported that serum CRP levels are higher in cases of invasive cancer than in cases of non-invasive cancer ... significance of interleukin serum levels in patients with ovarian cancer Br J Cancer 1995, 71:354-356 De Vita F, Orditura M, Auriemma A, Infusino S, Roscigno A, Catalano G: Serum levels of interleukin ... Murai M: Serum interleukin as a prognostic factor in patients with prostate cancer Clin Cancer Res 2000, 6:2702-2706 Wise GJ, Marella VK, Talluri G, Shirazian D: Cytokine variations in patients with...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo khoa học: "Successful enteral nutrition in the treatment of esophagojejunal fistula after total gastrectomy in gastric cancer patients" pps
... grams of protein per kilogram of weight per day, by using an infusion bomb during 20 hours, (with a resting time of hours) Results The complete closing of the fistula was evident in day 8, 14 ... the adequate place, in the intestinal lumen, distal to the zone of escape (Figure 4) This emphasizes the importance of experience in the handling of this alternative therapy In this case, a radiographic ... the fistula duct absolute restriction of oral route and the administration of antibiotics From the point of view of the nutritional assistance that these patients require, it always has been understood...
Ngày tải lên: 09/08/2014, 03:22
Báo cáo khoa học: "Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients" pot
... bacterial contamination by an aerobic and anaerobic bacteria are common causes of diarrhea after the radiation treatment of gynecological cancer Maintaining intestinal integrity during radiotherapy ... changes in intestinal flora mediated through fermented milk intake FEMS Immunol Med Microbiol 1994, 10:55-64 19 Salminen E, Elomaa I, Minkkinen J, Vapaatalo H, Salminen S: Preservation of intestinal ... evening), beginning days before starting radiotherapy and continuing everyday during radiotherapy In the other control group, an the identical-appearing placebo was administered in the same schedule...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo khoa học: "An ultrasonographic evaluation of skin thickness in breast cancer patients after postmastectomy radiation therapy" docx
... measurement points taken in patients with Grade Figure Erythema and dry desquamation seen in Grade grade 4) showed a convincing trend of an increased probability of thinning in the skin thickness ... following conservative surgery and irradiation Correlations of Acute skin scoring (RTOG) and fibrotic skin thickness Skin reactions occurring within a time interval of up to three months following ... assessment at the end of every radiotherapy treatment In this study, grade acute skin reaction was found in 72% of patients, grade in 22% of patients and grade and grade were found in 3% each No patient...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: " An ultrasonographic evaluation of skin thickness in breast cancer patients after postmastectomy radiation therapy" pptx
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "The evolution of rectal and urinary toxicity and immune response in prostate cancer patients treated with two three-dimensional conformal radiotherapy techniques" ppt
... toxicity observed in patients during their last inspection are shown In the cohort of patients included in the WP group, pretreatment GI toxicity of grade was found in the history of patients (1.72%), ... the diminution of late GI and GU toxicity to grades 0-1 in a majority of acute toxicities of patients suffering grades 1-3 The relevance of our study lies in the complex evaluation of clinical ... toxicity developed in 20 (24.69%) and grade in (1.23%) patients Late grade GU toxicity occurred in (8.64%) and grade in (7.41%) patients None of the patients in the cohort had grade of GU toxicity...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients" doc
... trypsin inhibitor (TATI), also called pancreatic secretory trypsin inhibitor (PSTI) and serine protease inhibitor Kazal type (SPINK1), is a biomarker of poor prognosis in colorectal cancer patients, ... a trypsin inhibitor that balances concentrations of trypsin and also functions as a weak inhibitor of other serine proteinases [10,11] In addition, TATI has been found to be involved in tissue ... [20] Interestingly, we found a significant post-operative increase in s-TATI concentrations in patients treated by short-term RT but not in long-term RT treated patients In line with previous findings,...
Ngày tải lên: 09/08/2014, 09:21
Báo cáo khoa học: " Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence" doc
... illustration of the protein with important areas such as substrate binding domains, Leucine zipper, ATP-binding domains, FAT domain and PI3K domain [17] together with exonic information (The size of the ... PI3K domain, substrate binding domains and ATPbinding domains, is illustrated in Figure Single marker associations Risk for developing breast cancer The association between any variant in the ATM ... both in monomeric (active) and dimeric (inactive) state [16] The protein contains several important domains such as 1) the C-terminal protein kinase domain (PI3K-domain), 2) the substrate binding...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Down-regulation of kallikrein-related peptidase 5 (KLK5) expression in breast cancer patients: a biomarker for the differential diagnosis of breast lesions" doc
... analysis of KLK5 in cancerous and benign breast lesions, targeting the evaluation of the clinical use of KLK5 expression for the discrimination of the malignant from the non-cancerous tumors of the ... potential as cancer biomarkers Clin Cancer Res 2003, 9:1710-20 18 Shinoda Y, Kozaki K, Imoto I, et al: Association of KLK5 overexpression with invasiveness of urinary bladder carcinoma cells Cancer ... (ER) staining (p = 0.028) of the breast cancer patients In more details, post-menopausal breast cancer women displayed a significant downregulated KLK5 expression profile, with 70.2% of them...
Ngày tải lên: 13/08/2014, 13:20
Radiogenomics in gynecological cancer patients doc
... Recombination IARC: International Agency for Research on Cancer IFNγ: Interferon-γ IGF1: Insulin-like Growth Factor-1 IL: Interleukin IMRT: Intensity Modulated Radiotherapy vi IVS: Intervening ... adjuvant chemotherapy For a minority of patients hormonal therapy is a therapeutic option (68) 1.2.1.3 Cancer of the endometrium Endometrial cancer, cancer of the lining of the uterus, is the most ... effective in selected patients with endometrial cancer (71) 18 1.2.1.4 Cancer of the vulva, vagina and choriocarcinoma Cancer of the vulva and the vagina are relatively rare malignancies, accounting...
Ngày tải lên: 05/03/2014, 13:20
Báo cáo khoa học: Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73c in lung cancer doc
... combinations between differential N-terminal domain and C-terminal domain [15] Despite the rarity of p73 mutations, overexpression of p73 isoforms is common in several types of cancer [14,16], including ... treatment of A549 cells with increasing concentrations of the Sp1 inhibitor mithramycin A (Fig 3B), which not only interferes with the transcription of genes containing GC-rich regions in their ... C-terminal domain of TAp73c is that, owing to the excision of exon 11 during alternative splicing, it lacks most of the Glu ⁄ Pro-rich domain and the Pro-rich domain, which are located in a region...
Ngày tải lên: 29/03/2014, 09:20
Báo cáo sinh học: "Elevated expression of CDK4 in lung cancer" pptx
... staining intensity and the percentage of positive staining areas of cells The staining intensity was scored as previously described(0-3) [8,9] and the percentage of positive staining areas of ... phosphorylating the retinoblastoma protein Overexpression of CDK4 has been described in many tumors, including lung cancer In this investigation, we analyzed the expression of CDK4 protein in lung cancer ... localization of CDK4 protein in 89 archived paraffin-embedded lung cancer samples and 23 normal lung tissues using immunohistochemical staining (Figure 1A-E) Specific CDK4 protein staining was found in...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo sinh học: " No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients" pdf
... Conclusion By examining the distribution of mast cells in the primary tumor, in lymph node metastasis and in the normal regional-draining lymph node in 93 stage IIIB colon cancer patients, we found ... evidence that infiltration of mast cells into primary cancer tissue impacted the progression of colon cancer *: MCCstroma, the count of tryptase-positive mast cells in the cancer stroma of the primary ... the infiltration of mast cells into primary colorectal cancers and the function of mast cells might vary with their location in cancer tissue, it is reasonable to examine the distribution of mast...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo hóa học: " Markedly impaired bilateral coordination of gait in post-stroke patients: Is this deficit distinct from asymmetry? A cohort study" ppt
... minutes, including the preparation time for the patient The post processing time was less than minutes including uploading, calculation and reporting In off-line analysis, only straight walking ... stepping coordination in post stroke patients What is the source of the dis-coordination of left-right stepping seen in the present study? Impairments in bilateral coordination of rhythmic arm swinging ... coordination of stepping in the pathophysiology of freezing of gait in Parkinson’s disease Mov Disord 2008, 23(Suppl 2):S444-S450 Ustinova KI, Fung J, Levin MF: Disruption of bilateral temporal...
Ngày tải lên: 19/06/2014, 08:20