levels enzyme activities and metabolites in diurnal cycles
Báo cáo khoa học: "The influence of the PRKAG3 mutation on glycogen, enzyme activities and fibre types in different skeletal muscles of exercise trained pigs" pot
Ngày tải lên :
12/08/2014, 18:22
... differences were seen in m longissimus dorsi and in m semitendinosus, muscles thus considered to be less involved during training on a treadmill [10] In both genotypes training adaptations in the fibres ... with myosin ATPase stains and type I and IIA+ IIX with myosin heavy chain antibodies NADH-tetrazolium reductase staining intensity was subjectively evaluated as low, medium and high in the different ... 0.05) in m biceps femoris and m longissimus dorsi in the carriers than in the noncarriers Discussion The main new finding of this study is, that after exercise training the PRKAG3 mutation influences...
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Báo cáo khoa học: Measuring enzyme activities under standardized in vivo-like conditions for systems biology pdf
Ngày tải lên :
06/03/2014, 09:22
... enzyme of interest should be investigated in the context of the in vivo-like medium Finally, in vivo, the enzymes are present at much higher concentrations than in typical enzyme assays, in which ... lines, there are many more metabolites in the cell than in our standardized medium, and each of them may have an effect on the kinetics of a particular enzyme However, it will be impossible and ... extracts are diluted The crowded intracellular environment may affect protein–protein interactions and thereby also the activities of the enzymes involved [58] As an indirect test, we have mimicked...
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Báo cáo khoa học: Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of b-lactam antibiotics pptx
Ngày tải lên :
08/03/2014, 08:20
... addressed the kinetic properties of the enzyme and mutants [4,9–13], investigations into the individual rate and binding constants underlying the kinetic properties and biocatalytic performance in the ... reversed binding of the substrate, in which the leaving group, p-nitrophenol, occupies the acyl binding site and the acetyl group binds at the leaving group binding site, sterically hindering the ... hydrolysis and synthesis of penicillin G, ampicillin and cephalexin Furthermore, insight into the nature of the transition state in the rate-determining steps of the reaction was obtained by analysing...
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Báo cáo y học: "Raised intrathecal levels of APRIL and BAFF in patients with systemic lupus erythematosus: relationship to neuropsychiatric symptoms" docx
Ngày tải lên :
09/08/2014, 10:23
... IgG-albumin ratio, IgG index, and the presence of oligoclonal bands have all been described with varying frequencies Increased levels of interleukin (IL)-1 [6], IL-6 [6,7], IL-8 [8], and interferon-gamma ... George-Chandy et al Figure Raised APRIL and BAFF levels in cerebrospinal fluid of systemic lupus erythematosus (SLE) patients Cerebrospinal fluid levels of (a) APRIL and (b) levels in cerebrospinal ... transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI), which are found mainly on B cells and plasma cells [14] In addition, BAFF binds to BAFF receptor found mainly on B cells,...
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Using short activities and game in the post speaking stage to increase grade 11 A4 students interets at Chan Mong hight school, Phu Tho Province
Ngày tải lên :
14/05/2015, 11:34
... from learning Usually, the students have more interest at the beginning of the lesson After doing many exercises and taking part in speaking activities in the pre- speaking and while- speaking stage, ... speaking activities 1.6 Short activities and games 1.6.1 The role of short activities and games in language teaching and 6 7 7 8 10 11 11 learning process 1.6.2 Principles of using short activities ... short activities and games in language teaching and learning process Short activities and games (or communicative activities) really play an important part in language teaching and learning Their...
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Báo cáo y học: " Decreased glutathione levels and impaired antioxidant enzyme activities in drug-naive first-episode schizophrenic patients" pptx
Ngày tải lên :
11/08/2014, 15:22
... Results Antioxidant enzyme activities and glutathione levels There was no significant correlation between age and AODS included enzyme activities and glutathione levels, in patients or healthy controls ... http://www.biomedcentral.com/1471-244X/11/124 and other thiol-containing groups also play critical roles as antioxidants GSH participates in the reduction of oxyradicals and its levels in the brain are high especially during early ... an increased activity of GPx and a decreased activity of CAT in RBCs (3) a positive correlation exists between the score of SAPS and the levels of GSHt and GSHr The findings of this study indicate...
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Báo cáo y học: "Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes" pptx
Ngày tải lên :
14/08/2014, 17:22
... changes in transcript and metabolite levels and enzyme activities during the diurnal cycle and an extended night (XN) Distribution of global changes in transcript and metabolite levels and enzyme activities ... changes in transcript levels, enzyme activities and metabolites in diurnal cycles reviews In pgm, most metabolites showed similar or smaller diurnal changes than in WT (Figure 4) The left-hand column ... changes in transcript levels, metabolites and enzyme activities during the diurnal cycle and an extended night Changes in specific transcripts, enzyme activities and metabolites in rosettes of Arabidopsis...
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Báo cáo Y học: The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme pdf
Ngày tải lên :
24/03/2014, 03:21
... CYP101, CYP108 and CYP102 that the N-terminal region encodes an amino-acid sequence that is involved in substrate recognition and binding as well as redox partner binding [20] This finding was also ... expressed in COS-1 cells in the presence of DOC, indicating that other amino acids, including some at the N-terminus, contribute to efficient CYP11B1 and CYP11B2 wild-type activity In addition, ... from the Protein Data Bank [31], using the SYBYL 6.6 subroutine COMPOSER (Tripos Inc., St Louis, MO, USA) The standard procedure of protein modelling using COMPOSER includes the following steps:...
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Báo cáo y học: "he Association Among Lipoprotein-associated Phospholipase A2 Levels, Total Antioxidant Capacity and Arousal in Male Patients with OSA"
Ngày tải lên :
25/10/2012, 11:00
... arousal index was associated with increased LP-PLA2 level The elevated levels of circulating LP-PLA2 may explain prone to sudden death due stroke and AMI in patients with OSA and increased arousal index ... divided into two groups according to the median arousal value and patients’ characteristics and laboratory findings were demonstrated in Table LP-PLA2, total cholesterol and triglyceride levels ... triglyceride levels were increased in patients above median arousal and TAC was reduced in these subjects Other demographic and laboratory findings were comparable in two groups According to the arousal...
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Annual and Diurnal Profiles of Cryptosporidium and Giardia in River Water in Japan
Ngày tải lên :
05/09/2013, 10:17
... batch mode, and the effluent discharge is normally performed in the morning and/ or evening Therefore, the concentration might increased in the morning and evening Actually, in the morning, we confirmed ... and diurnal differences in the concentrations of Cryptosporidium and Giardia in river water which is used for drinking water sources in Japan In addition, the relationship between microbial indicators ... Davis J P and Havens P L (1997) Cryptosporidiosis in children during a massive waterborne outbreak in Milwaukee, Wisconsin: clinical, laboratory and epidemiologic findings, Epidemiol Infect.,...
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iec 60076-3 power transformers - insulation levels, dielectric tests and external clearances in a
Ngày tải lên :
25/12/2013, 10:34
... applicable intable 1, astandardswitchingimpulsewithstandvoltage terminals according to table 4; (SI) for theline - a standard lightning impulse withstand voltage for line (LI) the terminals according ... neutral terminal, see 13.3.2 The test is intended to verify the impulse withstand voltage of the neutral terminal and its connected winding(s) to earth and other windings, and along the winding(s) ... strength of the line and neutral terminals and their connected windings to earth and other windings - Short-duration induced AC withstand voltage test (ACSD), see 12.2 and 12.3 Thetest is intended to...
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Tài liệu Changes in Business Cycles: Evidence and Explanations ppt
Ngày tải lên :
17/02/2014, 21:20
... genuinely aiming at price stability and attempting to restrain aggregate demand starting in 1955 It simply missed its target for a while because of outdated operating procedures and a misunderstanding ... expansions and inadequate restraint in the face of high growth and rising in ation is a topic of some debate De Long (1997) stresses historical accidents and a lingering fear of recession stemming from ... October 1979, and December 1988 For example, in September 1955, the FOMC voted for the “maintenance of, and preferably some slight increase in, the restraining pressure it had been exerting through...
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Báo cáo khoa họcRe-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme docx
Ngày tải lên :
06/03/2014, 00:20
... facilitating productive binding of the phosphorylated coenzyme by enlarging the potential binding pocket and removing the negative charge, likely to repel the 2Â-phosphate of NADP(H), and replacing ... entirely vindicating the initial thinking behind the mutagenesis Wider implications Careful purication of nicotinamide coenzymes has been recognized in the past as an important issue in the study ... dehydrogenase and its specicity, but also has wider signicance for the study of coenzyme specicity in other enzymes Coenzyme preference in glutamate dehydrogenase Results and Discussion Initial kinetic...
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Báo cáo khoa học: Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer’s disease brain doc
Ngày tải lên :
16/03/2014, 22:20
... Gingras AC, Sonenberg N & Thomas G (1997) The insulin-induced signalling pathway leading to S6 and initiation factor 4E binding protein phosphorylation bifurcates at a rapamycin sensitive point ... sectors, and the entorhinal and temporal cortice (Fig 4D), but weak staining in the granule layers of the dentate gyrus (not shown) In contrast, in control brain slices there was weak stainings in ... proteins with either polyglutamine or polyalanine expansions in Huntington disease, Huntington related diseases, and various forms of a-synuclein associated with Parkinson disease and synucleinopathies...
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Báo cáo Y học: Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot
Ngày tải lên :
17/03/2014, 17:20
... results indicate that Tk-G10A and Tk-G10S are functional both in vivo and in vitro, whereas Tk-G10L and Tk-G10P are not functional either in vivo or in vitro The kinetic parameters of Tk-G10A and ... the substrate binding affinity Binding analyses using BIAcore system To examine whether the mutation of Gly10 to Leu or Pro affects the substrate binding affinity of the protein, the interactions ... stable and active Introduction of the bulky side chains of Pro and Leu in this position causes a significant conformational change around the substrate binding site and active site, and thereby inactivates...
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Báo cáo khoa học: The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein ppt
Ngày tải lên :
30/03/2014, 14:20
... ADAM10 and TACE are involved in the shedding of APP, neither ADAM is involved in the shedding of ACE Furthermore we show that APMA can distinguish between the shedding of ACE and APP Materials and ... cleavage of APP in the human SH-SY5Y cells again underlines that TACE is not critically involved in APP shedding, at least in this cell line Although we failed to see an increase in the shedding of APP ... would appear that ADAM10 and TACE are not critically involved in the shedding of ACE APMA has been reported to induce the shedding of a number of protein ectodomains, including APP, from CHO cells...
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mirlin. statistics of energy levels and eigenfunctions in disordered systems
Ngày tải lên :
24/04/2014, 17:14
... results (3.75) and (3.78) of the non-perturbative calculation in this regime Furthermore, in the 1/g order [which means keeping only linear in terms in (3.84) and neglecting !i in denominator of Eq ... axis) obeying the Poisson statistics In particular, the variance of the number N of levels in an interval E increases linearly, var(N)"1N2, in contrast to the slow logarithmic increase in the RMT ... K0.00387, and a K0.0106 Note that for d(4 the sum in Eqs (2.25) and (2.26) converges, so that no ultraviolet cut-o! is needed Using now Eq (2.14) and calculating the remaining integral over...
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báo cáo hóa học:" Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study" potx
Ngày tải lên :
18/06/2014, 15:20
... measurements of fibrinogen-binding or expression of P-selectin Presented results are the mean-% of fibrinogen-binding and Pselectin expression ± SEM Reference values (obtained earlier during routine analysis ... function In this study, platelet adhesion to albumin, collagen and fibrinogen was investigated in the presence of soluble platelet activators including adenosine 5'-diphosphate (ADP), adrenaline, ... adhesion to albumin induced by simultaneous stimulation by LPA and adrenaline (a variable belonging to the LPA-factor in the present study) can be inhibited by inhibition of ADPsignalling in vitro [25]...
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báo cáo sinh học:" The role of nurses and midwives in polio eradication and measles control activities: a survey in Sudan and Zambia" pdf
Ngày tải lên :
18/06/2014, 17:20
... caring for, supporting and comforting clients; continuously assessing and monitoring health needs and responses to interventions; advocacy and education of clients and communities; and delivering ... at all levels; planning of activities with community involvement; and proper training of persons involved in programme implementation For supplementary activities, in contrast to routine activities, ... planning and budgeting for activities In addition, for the polio programme, nurses and midwives coordinated advocacy meetings at the district level and also organized sensitization meetings and...
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