lebrenne shahriar islam and malcolm r alison

Báo cáo y học: "Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation" pps

Báo cáo y học: "Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation" pps

... are expressed as mean ± standard deviation of four replicates from a representative culture of RA fibroblasts Similar values were obtained when the assays were carried out using two other fibroblast ... hours Values are expressed as mean ± standard deviation of four replicates from a representative culture of rheumatoid arthritis fibroblasts Similar values were obtained when the assays were carried ... cell preparations, with similar results Regression analysis was performed using Microsoft Excel Page of 10 (page number not for citation purposes) Arthritis Research & Therapy Vol No Hardy et...

Ngày tải lên: 09/08/2014, 08:22

10 438 0
Báo cáo khoa học: "A Construction-Specific Approach to Focused Interaction in Flexible Parsing" ppt

Báo cáo khoa học: "A Construction-Specific Approach to Focused Interaction in Flexible Parsing" ppt

... d e r R e c i p i e n t CC) SlotFiller: [DescriptionOf: Person FirstName: fred Surname: s m i t h Do you mean: t the messages from Fred Smith that arrived after January the messages from Fred ... Canyonflying to New York•" The ddhcully dr=seebeCauSethe ami0mgu=ty¢sstructural, structural arnblt'JllJtleSc~n occur no ma~er ~nat form of structure rs crtosen [ StructureType: Object ObjectName: ... used by other parts of the interface The actual grammar rules needed by FlexP are generated by first filling in a pre-stored skeleton pattern for NounPhrase, resulting in: The point here is not...

Ngày tải lên: 31/03/2014, 17:20

4 287 0
báo cáo hóa học: " Comparison of the discriminative ability of a generic and a condition-specific OHRQoL measure in adolescents with and without normative need for orthodontic treatment" potx

báo cáo hóa học: " Comparison of the discriminative ability of a generic and a condition-specific OHRQoL measure in adolescents with and without normative need for orthodontic treatment" potx

... irregularity + largest anterior mandibular irregularity + 2×(anterior maxillary overjet) + 4×(anterior mandibular overjet) + 4×(vertical anterior openbite) + 3×(anteroposterior molar relation) + 13 ... Performance scores were estimated by multiplying the corresponding frequency and severity scores The overall score for the CSOIDP attributed to malocclusion was the sum of the performance scores ... measures are complementary, rather than alternative sources of information Although this holds true for situations in which researchers are interested in assessing not only the overall profile...

Ngày tải lên: 18/06/2014, 19:20

6 594 0
báo cáo hóa học: " Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population" pot

báo cáo hóa học: " Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population" pot

... of the Chronic Respiratory Questionnaire, St Georges Respiratory Questionnaire and four other health-related quality of life instruments for patients with chronic lung disease Respiratory medicine ... or "role emotional") should correlate moderately to strongly with self-reported or doctor-diagnosed "depression" and only weakly with validation measures for physical impairment ("respiratory ... were present when the AQLQ domain scores were found between and 2, and and 7, respectively, and when the SF-36 domain scores were found between and 10, and 90 and 100, respectively For internal...

Ngày tải lên: 18/06/2014, 22:20

11 767 0
Báo cáo hóa học: " Experimental observations of rapid Maize streak virus evolution reveal a strand-specific nucleotide substitution bias" potx

Báo cáo hóa học: " Experimental observations of rapid Maize streak virus evolution reveal a strand-specific nucleotide substitution bias" potx

... commercial agriculture and basic subsistence farming throughout the tropical and temperate regions of the world [15-18] The geminiviruses are a highly diverse group comprising more characterised ... Sambrook J, Fritsch EF, Maniatis T: Molecular cloning: a laboratory manual Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY; 1989 Owor B, Martin DP, Shepherd DN, Edema R, Monjane AL, Rybicki ... JA, Rybicki EP: A three-nucleotide mutation altering the Maize streak virus Rep pRBR-interaction motif reduces symptom severity in maize and partially reverts at high frequency without restoring...

Ngày tải lên: 20/06/2014, 01:20

11 308 0
báo cáo hóa học:" Application of a disease-specific mapping function to estimate utility gains with effective treatment of schizophrenia" pot

báo cáo hóa học:" Application of a disease-specific mapping function to estimate utility gains with effective treatment of schizophrenia" pot

... of oral risperidone Assessments performed prior to this run-in period, however, were considered as the baseline for this analysis By protocol, pharmacokinetic considerations, and investigator judgment, ... function Summary of Fit RSquare RSquare Adj Root Mean Square Error Mean of Response Observations (or Sum Wgts) 0.043629 0.04147 0.112998 0.028649 445 Parameter Estimates Term Intercept Change ... development for disseminating the results of biomedical researc h in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical...

Ngày tải lên: 20/06/2014, 15:20

8 374 0
Báo cáo khoa học: " Effects of L-NAME, a non-specific nitric oxide synthase inhibitor, on AlCl3-induced toxicity in the rat forebrain cortex" doc

Báo cáo khoa học: " Effects of L-NAME, a non-specific nitric oxide synthase inhibitor, on AlCl3-induced toxicity in the rat forebrain cortex" doc

... nitrite concentrations after h in the ipsilateral forebrain cortex, and bilateral nitrite concentrations were unchanged after 30 d in this brain structure compared to the controls It has been previously ... irreversible protein impairment [10] Under our experimental conditions, h after L-NAME injection, there was increased bilateral NO production in the forebrain cortex compared to the control group ... control and the AlCl3-treated groups At h after L-NAME injection, ∙O2 production was decreased in the ipsilateral forebrain cortex compared with controls, and bilaterally for this brain structure...

Ngày tải lên: 07/08/2014, 23:22

8 288 0
Báo cáo khoa học: "Myxoid liposarcoma: a rare soft-tissue tumor with a misleading benign appearance" docx

Báo cáo khoa học: "Myxoid liposarcoma: a rare soft-tissue tumor with a misleading benign appearance" docx

... years after treatment, then annually for at least years after this Since sarcomas are exceedingly rare tumors, our review of the world literature provided very few studies on liposarcomas and ... pattern [8,10] In the present case (histopronostic grade featuring more than 10% of round cells), the presence of a great number of round cells is considered as the major predicting factor for prognosis, ... the surrounding structures and is well circumscribed Neither functional nor general symptoms are associated and routine blood tests are normal Such features suspects a common adipose tumor of...

Ngày tải lên: 09/08/2014, 04:21

6 213 0
Báo cáo y học: "Long-term cyclical in vivo loading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy study" ppt

Báo cáo y học: "Long-term cyclical in vivo loading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy study" ppt

... M, Carter DR: Articular cartilage functional histomorphology and mechanobiology: a research perspective Bone 2003, 33:1-13 29 Carter DR, Beaupre GS, Wong M, Smith RL, Andriacchi TP, Schurman ... Research Program (to ES) References 10 11 12 13 14 Carney SL, Muir H: The structure and function of cartilage proteoglycans Physiol Rev 1988, 68:858-910 Eyre D: Collagen of articular cartilage Arthritis ... deep zones were examined using Fourier Transform Infrared (FTIR) microspectroscopy FTIR microspectroscopy is a novel non-destructive method for visualizing the spatial distribution and the amount...

Ngày tải lên: 09/08/2014, 08:22

8 346 0
Báo cáo y học: "Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells" pdf

Báo cáo y học: "Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells" pdf

... Trizol Reagent (Invitrogen Corporation) were reverse-transcribed using random hexamers Realtime polymerase chain reactions were performed using 10 ng of cDNA and SYBR Green mix (Bio-Rad Laboratories, ... the proliferation, real-time reverse transcription- Table Reverse transcription-polymerase chain reaction primers for differentiation-specific gene expression analysis Genes Primer sequences ... 1.0) for sulfated proteoglycans Total RNA isolation and real-time reverse transcriptionpolymerase chain reaction Total cellular RNA samples extracted from day 21 monolayer and pellet cultures using...

Ngày tải lên: 09/08/2014, 10:23

12 359 0
Báo cáo y học: "Development and validation of the self-administered Fibromyalgia Assessment Status: a disease-specific composite measure for evaluating treatment effect" pptx

Báo cáo y học: "Development and validation of the self-administered Fibromyalgia Assessment Status: a disease-specific composite measure for evaluating treatment effect" pptx

... improve outcome measurement in rheumatology Trials 2007, 8:38 35 Turk DC, Dworkin RH, Allen RR, Bellamy N, Brandenburg N, Carr DB, Cleeland C, Dionne R, Farrar JT, Galer BS, Hewitt DJ, Jadad AR, ... ACR criteria for rheumatoid arthritis (RA) [20], who were randomly matched from 469 RA patients participating in an ongoing longitudinal outcome project and reflected the age/gender-related stratification/distribution ... better its discriminant power ROC = receiver operating characteristic Page of 12 (page number not for citation purposes) Arthritis Research & Therapy Vol 11 No Salaffi et al Table Convergent...

Ngày tải lên: 09/08/2014, 14:22

12 424 0
Báo cáo y học: " Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to " pdf

Báo cáo y học: " Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to " pdf

... Laboratories; all other tissue culture reagents were from GIBCO-BRL (Grand Island, NY) Kinase assay kits, U0126, and antibodies against phosphorylated and non-phosphorylated ERK1 and ERK2 were ... from several laboratories reported that SP-A interaction with macrophages and macrophage cell lines resulted in production of reactive oxygen and nitrogen species and inflammatory cytokines, and ... http://respiratory-research.com/content/10/1/60 59 60 61 62 63 64 65 66 Chroneos ZC, Abdolrasulnia R, Whitsett JA, Rice WR, Shepherd VL: Purification of a cell-surface receptor for surfactant protein...

Ngày tải lên: 12/08/2014, 14:20

11 435 0
Báo cáo y học: "The SLC2A9 non-synonymous Arg265His variant and gout; evidence for a population-specific effect on severit" docx

Báo cáo y học: "The SLC2A9 non-synonymous Arg265His variant and gout; evidence for a population-specific effect on severit" docx

... much greater re-uptake of urate from the lumen into the blood and reduced urinary urate excretion [15] In contrast, over-expression of the URAT1 renal urate transporter does not enhance urate reabsorption, ... Kimura T, Fukutomi T: Urate transport: regulators of serum urate levels in humans Curr Rev Rheumatol, in press 18 Wallace SL, Robinson H, Masi AT, Decker JL, McCarty DJ, Yu TF: Preliminary criteria ... articular chondrocytes and increase the risk for deposition of MSU crystals and formation of tophi in joint structures A further issue is that host factors other than hyperuricaemia may contribute...

Ngày tải lên: 12/08/2014, 15:23

25 266 0
Báo cáo y học: " Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons" pdf

Báo cáo y học: " Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons" pdf

... Offredo C, Pangon B, PierreAudigier C: Molecular fingerprinting of Mycobacterium tuberculosis and risk factors for tuberculosis transmission in Paris, France, and surrounding area J Clin Microbiol ... number not for citation purposes) Respiratory Research 2006, 7:77 http://respiratory-research.com/content/7/1/77 Table 1: Demographic and behavioral characteristics of the study participants Variables ... injected intradermally into the volar aspect of the forearm and transverse induration diameter was measured 72 hours later Individuals performing the TST were blinded to QFT-G results and vice-versa...

Ngày tải lên: 12/08/2014, 16:20

9 434 0
Báo cáo sinh học: "Syntenator: Multiple gene order alignments with a gene-specific scoring function" docx

Báo cáo sinh học: "Syntenator: Multiple gene order alignments with a gene-specific scoring function" docx

... assignment and conservation of gene orders are interlinked and should be jointly studied Boyer et al [10] present a generic approach to merge information from two or more primary graphs They ... Syntenator Syntenator combines conservation of gene order and local sequence similarity to deduce gene orthology Partial order alignments are represented by partial order graphs (POG) We present ... the recurrence relation We need to modify the recurrence relation of the traditional Smith-Waterman approach to work on POGs To compute a maximal alignment score for a particular pairing of vertices...

Ngày tải lên: 12/08/2014, 17:20

12 236 0
Báo cáo y học: "Latency profiles of full length HIV-1 molecular clone variants with a subtype specific promoter" pps

Báo cáo y học: "Latency profiles of full length HIV-1 molecular clone variants with a subtype specific promoter" pps

... of reverse transcription and provirus formation, we performed a real-time TaqMan assay to score the average number of HIV-1 DNA copies per cell We measured no difference between TNFa induced and ... CA-p24 was corrected for the percentage of intracellular CA-p24 positive cells Results are shown as the ratio of extracellular versus intracellular CA-p24 The results presented are the average values ... demonstrate that latency gets more dramatic over time Similar experiments were performed with the HDAC inhibitor Vorinostat (Figure 3B and 3D) Over time, both mock and Vorinostat treated cultures...

Ngày tải lên: 13/08/2014, 01:21

12 238 0
Báo cáo y học: "Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell line" ppsx

Báo cáo y học: "Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell line" ppsx

... Faucette, Frank Malik and Dr Lily I Cheng Dr Sandra Ruscetti, NCI, kindly provided the anti-Rauscher p30 goat antiserum Dr Bruce Chesebro, NIAID, kindly provided MAb 538 References Abbreviations ... PZ performed electron microscopy and first found the virus particles AM, JWH and JMW carried out mouse studies JWH and JMW drafted the paper Acknowledgements This work was supported in part by ... Division of Cancer Treatment, NCI, Frederick, MD and studied under NIAID Animal Care and Use Committee approved protocols and housing Mice were observed for to 12 months and necropsied when signs...

Ngày tải lên: 13/08/2014, 06:20

6 330 0
A site specific design of a fixed pitch fixed speed wind turbine blade with multiple airfoils as design variable

A site specific design of a fixed pitch fixed speed wind turbine blade with multiple airfoils as design variable

... they are referred as root, mid, and tip airfoils for simplicity 3.1 Chord and twist distributions Bezier curves require four control points each containing two coordinates, in this case the first ... Agriculture (USDA) for their support to this project via the BuildinG a Regional Energy and Educational Network (BGREEN) grant References [1] R Wiser, 2012 Wind technologies market report (2014) [2] R. W ... FPFS rotor with different airfoils with variable relative thickness described by four Bezier curves; the chord and the twist are also modeled using one Bezier curve each In particular the airfoils...

Ngày tải lên: 09/09/2015, 10:17

12 347 0
Glial cell line drived neurotrophic factor (GDNF) family of ligands is a mitogenic agent in human glioblastoma and confers chemoresistance in a ligand specific fashion

Glial cell line drived neurotrophic factor (GDNF) family of ligands is a mitogenic agent in human glioblastoma and confers chemoresistance in a ligand specific fashion

... Randomised Control Trial RET Rearranged during transfection RF Radiofrequency RNA Ribonucleic Acid RT Reverse Transcription RTK Receptor Tyrosine Kinase RTOG Radiation Therapy Oncology Group SCC Squamous ... Ebstein-Barr Virus ECM Extracellular Matrix EGFR Epidermal Growth Factor Receptor EOR Extent of resection ErbB2/HER2/Neu v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma ... hallmark is the presence of prominent microvascular proliferation and/ or necrosis 1.3 Malignant Astrocytoma Malignant astrocytomas are the most frequent primary brain tumours in adults and represent...

Ngày tải lên: 14/09/2015, 12:13

203 290 0
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