... 1999) In ewes, the ram effect has been extensively used to induce out-of-season estrus in order to obtain births during autumn (Martin et al 1986) Introducing rams to previously isolated ewes induces ... determines changes in endocrine and follicular profiles, estrous onset, ovulation and pregnancy rates A second objective was to characterize the ovarian response and the endocrine profiles in MAP-primed ... stimulated during the non-breeding season, and to determine if the endocrine stage at ram introduction may affect estrous expression and first ovulation Materials and methods Experiment The experiment...
Ngày tải lên: 12/08/2014, 15:21
... hypoxia 696 and emersion showed a 3-fold increase in glucose and a more than 30-fold increase in lactate, whereas the levels in controls remained constant The arginine kinase gene (AK) and the eukaryotic ... (peaks and 2), ranging from : for Cal sapidus, to : in Car maenas, to : 10 in Can pagurus [29,30], yielding peak as the major CHH The immunohistochemistry studies show that the intrinsically staining ... from the surface of the PO and into branchiocardiac veins through the direct openings of anterior and posterior bars [35] Furthermore, considering the localization of PO-CHH-producing cells in the...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo lâm nghiệp: "Oak growth, development and carbon metabolism in response to water stress" pps
... stress face the conflicting problem of maintaining some degree of photosynthesis while minimizing water loss Stomatal control in response to varying moisture stress is the first and perhaps the most ... potential continued to decrease, indicating that Q macrocarpa could not utilize rain water in the upper soil layers and Knapp, 1986) The ability to increase root growth into and to increase root proliferation ... photochemistry and quantum yield remained stable with increasing water stress and thus could not explain the nonstomatal response indicated by analysis of the A/C i curves Nonstomatal response to water...
Ngày tải lên: 08/08/2014, 18:21
Báo cáo lâm nghiệp: " Radial growth of mature pedunculate and sessile oaks in response to drainage, fertilization and weeding on acid pseudogley soils" ppt
... poor In winter and spring, during rainy periods, the water table rises close to the surface (0 to -5 cm); in an average year, it is prea sent from the middle of November to the end of May The ... divided into two parts in the spring of 1974 One part remained untouched; the other was drained by digging ditches, about 10 to 20 m away from one another Some measurements indicated that the corresponding ... from 1974 to 1991 (fig 1b) The difference in the reaction son In the Molinia site, a strong positive interaction was observed between weeding and drainage, in the young trees as well as in the old...
Ngày tải lên: 08/08/2014, 18:21
Báo cáo y học: "Human meniscus cells express hypoxia inducible factor-1α and increased SOX9 in response to low oxygen tension in cell aggregate culture" ppsx
... differently in cells in the outer and inner regions of the human meniscus [44-48] We also wished to determine whether the cells isolated from the outer and inner meniscus in culture differed in their response ... was absent from the outer region In order to determine whether these differences in expression in vivo were reflected in different responses inherent in the cells present in inner and outer meniscus, ... important in determining the phenotype of the inner meniscus Competing interests The authors declare that they have no competing interests Authors' contributions ABA conceived, designed and executed the...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: " Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilag" pps
... especially due to the presence in the OA joint of proinflammatory catabolic cytokines such as IL-1β, which has been shown to induce GLUT-1 expression both in the present study (Figure 2) and in other studies, ... identical to and reflects that in the plasma, both under normal conditions and in noninflammatory and inflammatory types of arthritis, excluding those associated with infections [12] To our knowledge, ... contributes to cartilage degradation in late OA In another study, exposure to either low or high glucose concentrations induced insulin-like growth factor-1 The aim of the present study was therefore to...
Ngày tải lên: 09/08/2014, 14:21
báo cáo khoa học: " Comparison of the transcriptomes of American chestnut (Castanea dentata) and Chinese chestnut (Castanea mollissima) in response to the chestnut blight infection" doc
... tissues To gain insight into the differences in the response of the American and Chinese chestnut species to infection by the blight-causing agent, we compared the transcriptomes from Chinese chestnut ... AB contributed to extracting RNA and making the 454 libraries, curated and analyzed the data, supervised the work SC and YZ, and wrote the paper CS and YZ contributed to the bioinformatics analyses ... responses The trees try first to block the progression of the pathogen by increasing the expression of hydrolases, lignin synthesis, and cell death The infection is also sensed by mitogen kinases,...
Ngày tải lên: 12/08/2014, 03:20
Báo cáo y học: " Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis" doc
... bleomycin challenge further increased cathepsin K mRNA and protein levels both in wild-type mice and in transgenic mice A more precise understanding of the factors governing cathepsin K regulation in ... proved to be minimally effective in limiting alveolitis and modifying the course of the disease, thus underlining the urgent need for novel therapeutic intervention strategies Cathepsin K (Cath ... significantly increased in the wildtype mice but not in the cath K overexpressing mice in response to bleomycin challenge, whereas the classical parameter to determine changes in lung elasticity due to...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: " γδ T lymphocytes from cystic fibrosis patients and healthy donors are high TNF-α and IFN-γ-producers in response to Pseudomonas aeruginosa" pptx
... proliferation in relation to clinical severity of patients (data not shown) Discussion The present study is the first, to our knowledge, that determines the "in vitro" intracytoplasmic cytokine response to ... Measurement of single cell intracellular cytokines allowed us to determine the kind of produced cytokines and which T subpopulation was their source This system avoided the purification of a minor T subset, ... CD45RO-positive cells to an effector function [28] This marker is then expressed by both memory and effector T cells To assess the type of cytokines secreted in response to PA, intracytoplasmic IL-4,...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo khoa học: " Germination of Pinus pinaster, P. radiata and Eucalyptus globulus in relation to the amount of ash produced in forest fires Otilia" doc
... unknown The aim of this experiment was to analon the seed germination of Pinus pinaster Aiton, Pinus radiata D Don and Eucalyptus globulus Labill and yse the effect of ash to determine whether ash ... conditions which include a more or less abundant ash bed, depending on the intensity of the fire and the type and amount of fuel Ash may influence the germinative process and later seedling development ... burn and the rainfall m in that region during the first rains after the burn [29] The ash treatment involved placing 0.454 g ash on Petri dishes (this quantity coincides with that found on the...
Ngày tải lên: 08/08/2014, 14:21
Curricular change in response to the 150 hour law for CPA exam candidates, a case study of business departments at three colleges
... this process The study’s findings were grouped under four main themes: constructing the path, on the path to the goal, guiding the routes and paths, and the finish line Subthemes and categories ... passing this exam and entering the profession Following is a history of the CPA exam and the events leading up to the 150-Hour Law History o f Accounting Education and the 150-Hour Law In the nineteenth ... mission of the college The attempt to halt the interest fails, and the administration and faculty then ignore the interest in the new subject Lastly, administration, surrendering to student interests,...
Ngày tải lên: 30/09/2015, 13:42
Tài liệu Báo cáo khoa học: Analyzing changes of chromatin-bound replication proteins occurring in response to and after release from a hypoxic block of replicon initiation in T24 cells pptx
... before the end of the respective incubation conditions, in case of hypoxic labeling by plunging a spatula carrying the appropriate quantity in dried form into the cell culture medium To stop incubations ... by Triton buffer was high in the same cells These results clearly show that the PCNA staining is colocated with the BrdU staining and this again signifies that PCNA is only bound to chromatin portions ... state in a satisfying specific manner The same problem occurred with the other cell lines examined Inhibitors such as thymidine or aphidicolin were not used, as they inhibit elongation and not...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx
... activating mutations in the EGFR tyrosine kinase domain; these primary mutations correlate well with clinical responses to the EGFR-specific, ATP-competitive tyrosine kinase inhibitors gefitinib and ... phosphorylating BIMEL to allow binding of RSK, which in turn dissociates to allow binding of bTrCP1 ⁄ 2? Are these events coordinated by a scaffold protein that brings the components together at the ... impairs imatinib binding [58,59] Accordingly, new therapies are being tested and these include second-generation tyrosine kinase inhibitors, such as dasatinib (inhibits BCR–ABL, KIT, PDGFR and SRC...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing docx
... Cells on the wound edge were divided equally into three sectors, including the front sector between the nucleus and the leading edge The Golgi in the front sector was determined to be in the polarized ... activity during cell polarization Multiple tyrosine residues in the substrate-binding domain of Cas are phosphorylated in response to various extracellular stimuli, including integrin-mediated ... ⁄ 3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways Mol Biol Cell 9, 3367–3382 34 Miyamoto Y, Yamauchi...
Ngày tải lên: 23/03/2014, 03:20
Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... MAPK and triggers its dissociation from the cytoskeletal protein GKAP, therefore releasing it from the cytoskeleton into the cytoplasm [3] Our aim in this study was to gain a better understanding ... sorbitol (60 min) and then incubated in sorbitol-free medium (6 h) Detached cells were washed with NaCl ⁄ Pi and cells remaining attached to the dish were treated with trypsin and counted using ... 60 min, and then incubated for h in sorbitol-free medium (in the continued absence or presence of the inhibitor) Endogenous levels of hDlg were analysed by immunoblotting (lower) and the percentage...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL-induced apoptosis in breast cancer cells pdf
... proteins involved in various cellular processes, including inhibition of apoptosis Hypoxia has been reported to inhibit apoptosis induced by tumor necrosis factor-related apoptosisinducing ligand ... sought to determine whether TRAIL was involved in the localization change First, we assessed whether there was a change in TRAIL expression in MDAMB-468 cells in response to hypoxia by analyzing ... TRAIL signaling, leading to the activation of two distinct pathways One pathway might lead to increased nuclear localization of BRCA1 and the other to apoptosis Hypoxia could block the apoptotic arm...
Ngày tải lên: 30/03/2014, 03:20
Báo cáo khoa học: Molecular identification and expression study of differentially regulated genes in the Pacific oyster Crassostrea gigas in response to pesticide exposure doc
... b-1,3-Glucan binding protein 3e-6 Procathepsin L 1e-12 Meningioma expressed antigen 7e-19 Lipoprotein receptor related protein 2e-24 Fucolectin-1 6e-4 Cytoskeleton Tubulin alpha chain 4e-40 Tubulin beta ... genes in common to both the ADI and glyphosate response SSH libraries These were glutamine synthase, ATP synthetase, b-1,3-glucan binding protein and some housekeeping genes such as tubulin and ... preventing the plant from producing an essential amino acid and by inhibiting the enzyme enolpyruvylshikimate-phosphate synthase which reduces the production of protein in the plant, thereby inhibiting...
Ngày tải lên: 30/03/2014, 15:20
Báo cáo sinh học: " High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" potx
... GSK1070916 The cell line response data was compared to the mutation patterns in the cell lines, gene expression patterns and the karyotypes of the cell lines High chromosome number in the cell lines ... Aurora inhibitors These findings warrant further investigation about the relationship of chromosome number in primary and secondary populations of the tumor during and after treatment to monitor ... lymphoma cell lines, of the cell lines were resistant to GSK1070916 and contained low chromosome number in the primary population of cells However, when in reviewing the ploidy content in the cell...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học: " Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide" ppt
... closest to brain endothelial cells, wrapping around them, joined to them by gap junctions, and interfacing with them by peg -and- socket structures [2,3] These cells are also essential for the induction ... pericytes by LPS Another interesting finding of our study is related to the production of important signaling molecules, cytokines and chemokines by pericytes Of 23 cytokines and chemokines that we ... macrophage-colony stimulating factor, eotaxin, CCL-3 and CCL-4 To further characterize pericyte immune capacity, we determined the effect of LPS on the release of cytokines and chemokines The results (Figure...
Ngày tải lên: 19/06/2014, 22:20
o cáo hóa học:" High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" ppt
... GSK1070916 The cell line response data was compared to the mutation patterns in the cell lines, gene expression patterns and the karyotypes of the cell lines High chromosome number in the cell lines ... Aurora inhibitors These findings warrant further investigation about the relationship of chromosome number in primary and secondary populations of the tumor during and after treatment to monitor ... lymphoma cell lines, of the cell lines were resistant to GSK1070916 and contained low chromosome number in the primary population of cells However, when in reviewing the ploidy content in the cell...
Ngày tải lên: 20/06/2014, 04:20