lcc modeling as a decision making tool in pipeline design

... trial reduction in test requesting was partially mediated by a change in intentions In our experience, formal mediational analyses have been rarely used to investigate the causal factors in KT ... this article as: Ramsay et al.: Using the theory of planned behaviour as a process evaluation tool in randomised trials of knowledge translation strategies: A case study from UK primary care Implementation ... information system This data are routinely collected and ascribed to the primary care practice and could not accurately be attributed to individual primary care doctors Statistical analysis In all...

Ngày tải lên: 10/08/2014, 10:23

... behavioral and attitudinal aspects of individuals An in- depth analysis in each of the broad parameters revealed the following: Educational Facet Education plays a vital role in shaping up a personality ... data was tabulated and analyzed through qualitative analysis of the gathered data, which reveal the behaviors and decision making patterns in lower income populations towards regulated microfinance ... redesign their marketing strategies with massive penetration campaigns in the lower income groups and increased availability of branches in areas having lower income populations Moreover, a flexible...

Ngày tải lên: 06/09/2013, 05:48

... to access various sources of information nowadays Manual works in manufacturing has a negative relation with the number of machines that are equipped in factories For example, in the past, a car ... managers in maintaining the efficiencies of financial activities By following annually reports, managers can predict the trend of products in next year as well as figure out the reasons for inefficient ... reducing, products quality improvements and saving manufacturing time can be listed as three main benefits that ABC can bring to organizations in operational performances aspect (Anderson and...

Ngày tải lên: 13/03/2014, 14:19

... allergic diseases (e.g as carrier ⁄ adjuvants in the design of vaccines for immunotherapy of type allergy) In order to generate a universal affinity matrix for binding of any kind of biotinylated ... Schematic drawing of the isolation of native S-layer proteins from bacterial cells and the reassembly of native and recombinant S-layer proteins into crystalline arrays in suspension, on a solid ... structural organization principles have been identified A cell-wall-targeting domain was found at the N-terminal region of many S-layer proteins, which mediates binding to a specific heteropolysaccharide,...

Ngày tải lên: 16/03/2014, 12:20

... academic field of business a feasibility analysis is developed to help a client make a game-changing decision My feasibility analysis follows the general criteria of an analysis including: basic ... unbiased information While CEOs understand in principle that everyone who seeks their attention has an agenda, they don't always know a bias when they see one." This was a challenging balance ... potential place in the paper industry I quickly realized that Booshoot can innovate and create value In the United States 80% of the raw material used in making paper is wood Booshoot can create value...

Ngày tải lên: 18/03/2014, 02:20

... the town about it, he just went home and fell asleep Landing the fish did not matter to the old man only to get it as far as the side of the boat The Old Man And The Sea portrays Hemingway Code ... potential As Heros they try their hardest to persevere under pressure and achieve the goal in front of them They show the characteristics of a stoic, working hard in the hardest of situations Hemingway ... offered each other the best of company While out at sea Santiago is constantlywishing the boy was there to talk to or to help with the mighty fish Santiago does not have relationships with any of...

Ngày tải lên: 21/03/2014, 22:50

... WHO Library Cataloguing -in- Publication Data Management of solid health-care waste at primary health-care centres : a decision- making guide 1.Medical waste - standards Medical waste disposal - methods ... safe management of health-care waste pages, available on www.who.int/water_sanitation_health, under health-care waste or www.healthcarewaste.org Health-care Waste Management - Policy Paper and ... www.healthcarewaste.org Available materials Aide-mémoire for a national strategy for health-care waste management This aide-mémoire summarizes basic activities to be undertaken at national and local...

Ngày tải lên: 22/03/2014, 16:21

... of a systematic alanine-scan of a shorter IAPP fragment (Table 1) indicated that other than phenylalanine, any amino acid within the fragment could be replaced by alanine without losing the ability ... recognition interface that can be interrupted by aromatic intercalation This situation is very similar to aromatic DNA-intercalating agents Although DNA is the most important biological assembly stabilized ... important information of the role of aromatic moieties in amyloid fibril formation [36–41] A parameter-free model based on the mathematical analysis of many peptide fragments and their analogues had...

Ngày tải lên: 23/03/2014, 11:20

... Immunoprecipitation and SDS/PAGE Materials and cell lines The mAbs V.1 and V.5 against GPV, ALMA.12 against GPIba, ALMA.16 against GPIX and RAM.1 against GPIbb, were developed in our laboratory [19] ... Strassel, C., Baas, M.J., Salamero, J., ChasserotGolaz, S., Cazenave, J.P., De La Salle, C & Lanza, F (2001) Biosynthesis and intracellular post-translational processing of normal and mutant platelet ... band was composed of three or four different molecular mass forms Parallel analysis of the supernatants revealed a positive signal starting at 60 of chase and having a molecular mass (82 kDa) consistent...

Ngày tải lên: 23/03/2014, 13:20

... Groot et al (1999) have extensively evaluated bast fiber as a papermaking raw material using a variety of pulping methods Their findings indicate that industrial hemp bast fiber has a wide range ... source of papermaking fiber For example, paper was invented in China in A. D 105, but it was not until about 1850 that wood began to be used as a principal raw material for papermaking Early sources ... United States, plantations are also predicted to supply increasing quantities of wood fiber in the decades ahead In fact, a recent estimate indicates that increasing volumes of plantation pine in the...

Ngày tải lên: 24/03/2014, 05:20

... proteins such as NEMO may sterically hinder RIP1 from interacting with downstream death mediators such as caspase or RIP3, which not have ubiquitin-binding domains Ubiquitination of RIP1 may also ... key event in NF-kappaB activation [corrected] Nat Cell Biol 8, 398–406 Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S et al (2009) Involvement ... Dual cell-death checkpoints during TNFR1 signaling M A O’Donnell and A T Ting (TRAFs) and cellular inhibitor of apoptosis protein (cIAPs) was identified as a key checkpoint in TNFR1 death signaling...

Ngày tải lên: 28/03/2014, 23:20

... give various final concentrations as described in the results section Each experiment was done in triplicate Caspase-3/7, -8, and -9 activity assay Caspase activity was measured using Caspase-Glo™ ... CA) Relative activity was calculated based on readings measured from untreated cells after subtracting blank values Baseline was set to 100 units Each sample was measured in triplicate Cytokine ... 12, and 24 hours "0" designation represents non-treated controls (a) Activity of capase-3, -8, and -9 was measured using Caspase-Glo assay, and (b) effect on XIAP, Caspase-2, and Bid was determined...

Ngày tải lên: 18/06/2014, 15:20

... this article as: Rahma et al.: A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma Journal of Translational Medicine 2010 ... adjuvant administered subcutaneously as easy and practical as they may be–reverse gradually as soon as vaccinations are completed Accordingly, we believe that such treatment needs to be continued ... and 6) pre and postvaccination The postvaccination samples were taken during the last vaccination visit for every patient except patient whom the last available T regs sample was during vaccination...

Ngày tải lên: 18/06/2014, 16:20

... the data analysis and interpretation, and also participated in writing the manuscript All authors read and approved the final manuscript References It is important to note that this type of analysis ... items in the scale Finally, a measure of reliability, the Person Separation Index (PSI), was computed This is equivalent to Cronbach's alpha but has the linear transformation from the Rasch model ... of as many animals as possible in two minutes (ten is the pass mark) Finally, 'motor perseveration' tests executive function in five trials Subsequently a total screening score is calculated as...

Ngày tải lên: 20/06/2014, 15:20

... for children ages 2–4 DataStat, a nationally-based survey administration firm located in Michigan, was contracted to administer the California SCHIP statewide mail survey DataStat mailed the PedsQL™ ... (22.2%) Hispanic/Latino, (9.7%) Black/African American, (9.7%) Asian/Pacific Islander, 2(2.8%) Native American or Native Alaskan, and (12.5%) missing The statewide SCHIP sample was representative of ... trial endpoints, and include multi-item HRQOL instruments, as well as single-item measures (e.g., pain visual analogue scale), daily diaries, treatment adherence, and healthcare satisfaction [15,16,23]...

Ngày tải lên: 20/06/2014, 15:20

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Ngày tải lên: 07/08/2014, 18:21

... Narahara H, Hara T, Takagane A, Akiya T, Takagi M, Miyashita K, Nishizaki T, Kobayashi O, Takiyama W, Toh Y, Nagaie T, Takagi S, Yamamura Y, Yanaoka K, Orita H, Takeuchi M: S-1 plus cisplatin ... Nash A, Sacks N, Ford H, Carter R, Hill A: A phase II study in advanced gastro-esophageal cancer using epirubicin and cisplatin in combination with continuous infusion 5-fluorouracil (ECF) Ann ... with advanced gastric cancer Cancer Chemother Pharmacol 2009, 64:877-883 Yoshida K, Hirabayashi N, Takiyama W, Ninomiya M, Takakura N, Sakamoto J, Nishiyama M, Toge T: Phase I study of combination...

Ngày tải lên: 09/08/2014, 03:21

... regression analyses as independent variables and resistin as a dependent variable A forward stepwise method was used ESR and S-creatinine were defined as normal or pathological according to standard laboratory ... variables Analyses were also performed with z score total hip and radius as dependent variables using a cutoff value as -1 SD for normal or reduced bone mass Resistin was significantly associated ... lupus erythematosus An association between resistin and inflammation has been reported in several different diseases, including RA [21] and inflammatory bowel disease [5], but is very weak or nonexistent...

Ngày tải lên: 09/08/2014, 10:22

... is available for review by the Editor -in- Chief of this journal Abbreviations ALB: albumin; AN: anorexia nervosa; AST: asparate aminotransferase; ALT: alanine aminotransferase; BCAA/AAA: branch-chain ... spleen in a patient with AN and elevated transaminases, whereas liver steatosis was diagnosed in ultrasound imaging, as was found in our patient In addition, these authors detected increased markers ... magnetic resonance imaging, and magnetic resonance angiography of the head showed no abnormality Aspartate aminotransferase was 3194 IU/L (reference range, to 38 IU/L); alanine aminotransferase,...

Ngày tải lên: 11/08/2014, 02:21

... analyst/manager dyads were asked to participate and four declined The reasons given for declining included vacancies in the data analyst position, and already having access to a commercial GIS tool Data ... their raw data into meaningful evidence for informed decision- making The use of maps and mapping is increasingly recognized as a key knowledge translation tool to assist in the transformation ... http://www.implementationscience.com/content/3/1/4 Finally, data analysts were involved in two separate daylong training sessions for each release phase of EYeMap Following the first training day, analysts were able to test out the software...

Ngày tải lên: 11/08/2014, 05:22