... treatment of muscle invasive bladder cancer? Oncol Rev 2011 doi:10.1186/1756-8722-4-35 Cite this article as: Ismaili et al.: Chemotherapy in advanced bladder cancer: current status and future Journal ... OncologyGroup J Clin Oncol 2004, 22:220-8 27 Waxman J, Barton C: Carboplatin-based chemotherapy for bladder cancer Cancer Treat Rev 1993, 19(Suppl C):21-5 28 Redman BG, Smith DC, Flaherty L, Du W, Hussain ... A, Fimmers R, Siener R, AUO Bladder Cancer Group: Randomized phase III trial of 2nd line gemcitabine and paclitaxel chemotherapy in patients with advanced bladder cancer: short-term versus prolonged...
Ngày tải lên: 10/08/2014, 21:23
... efforts to bring together existing toxicological 773 information on reproductive toxicology in an electronic format For data that are publicly 774 available (i.e not Confidential Business Information), ... possibility to build local (Q)SARs and 910 perform read-across These are currently limited and can be performed only for obvious 911 (structural) analogues for which a mechanistic basis may be known ... (non-animal) methods for cosmetics testing: Current status and future prospects - A report prepared in the context of the 7th amendment of the cosmetic directive for establishing the timetable for phasing...
Ngày tải lên: 05/03/2014, 16:20
Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx
... models for bladder cancer Expression of IGF2-P4 and H19 transcripts in heterotopic subcutaneous tumors In order to develop a model for heterotopic bladder tumors, T24P or HT-1376 human bladder cancer ... therapy of bladder cancer than subcutaneous implantation of bladder cancer cells (heterotopic model) Therefore, a mouse model was developed by intravesical instillation of T24P human bladder carcinoma ... as a major mechanism for the IGF2 overexpression in a variety of tumors including bladder carcinoma, hepatocellular carcinoma, breast cancer, ovarian cancer and prostate cancer [19-22] The human...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo khoa học: "Independent position correction on tumor and lymph nodes; consequences for bladder cancer irradiation with two combined IMRT plan" pptx
... the results for rectum are for 19 patients The V95% of the femoral heads was zero for all options in all patients For the bladder as OAR, we determined the hot spots in the same way as for the small ... radiotherapy for bladder cancer Radiother Oncol 2009, 93:364-367 Pos FJ, Hulshof MC, Lebesque JV, Lotz HT, van Tienhoven G, Moonen L, Remeijer P: Adaptive radiotherapy for invasive bladder cancer: ... literature on bladder tumor deformation is not unequivocal Lotz et al found that bladder tumor tissue is very rigid and that only small deformations occur [4] However, Chai et al found that deformations...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: " Hypofractionated radiotherapy after conservative surgery for breast cancer: analysis of acute and late toxicity" ppt
... to 10 Gy for early reactions, Gy for late reactions In the group assigned to receive 45 Gy to the whole breast, BED was 55 Gy for early effects, 78 Gy for late effects versus 60 Gy for early ... maximum dose 0.0009 Surgery 0.584 IQR = interquartile range KPS = Karnofsky performance status T = tumor N = lymph-node ** > 53.5 Gy for conventional fractionation and > 48.1 Gy for hypofractionation ... performance status, tumour stage, adjuvant chemotherapy and hormone treatment Differences were observed for lymph node stage, breast volume and breast maximum dose (Table 1) Median time from surgery...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo y học: "Pancreatic and psoas abscesses as a late complication of intravesical administration of bacillus Calmette-Guerin for bladder cancer: a case report and review of the literature" ppt
... BCG has proved to be an effective form of treatment for some stages of bladder Figure Computed tomography scan showing 43 mm abscess affecting the pancreatic head cancer [4] There are specific risks ... Surgical exploration and drainage were performed and cultures of the purulent material were positive for M bovis Urine and blood cultures were negative for acidfast bacilli stains Antitubercular ... head and right psoas muscle diagnosed years after intravesical treatment with BCG therapy for bladder cancer Case presentation An 83-year-old Caucasian man was hospitalized with a 2-month history...
Ngày tải lên: 11/08/2014, 17:21
Báo cáo y học: "Current Status of Methods to Assess Cancer Drug Resistance"
... [19] Prostate cancer Harper ME [20], Bright RK et al [21] Breast cancer O’Hare MJ [22], Speirs V [23] Cervical cancer Stern P et al [24] Bladder cancer Fu VX et al [25] Head and neck cancer Edington ... resistance in breast cancer identified by proteomics: Current status Cancer Letters 2010; 294: 13-24 56 Dupuy A, Simon RM: Critical review of published microarray studies for cancer outcome and ... predictive tests for cancer chemotherapy Cancer Treatment Reviews 1982; 9: 267-298 38 Weisenthal LM Predictive assays for drug and radiation resistance In: Masters JRW, ed Human Cancer in Primary...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo khoa học: Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer pdf
... TTA loops is ligand dependent, and therefore structural information for a given class of ligand would be highly desirable Also, there are G-quadruplexes as cancer drug targets no experimental structural ... DNA affinity (and therefore more generalized toxicity), and assays for duplex:quadruplex selectivity are routinely performed in many laboratories The structural requirements for selectivity have ... G-quadruplexes as cancer drug targets 10 11 12 Acknowledgement 13 I am grateful to Cancer Research UK for Programme Grant support and a Professorial Fellowship, and to my colleagues for their input...
Ngày tải lên: 06/03/2014, 09:22
MULTIPLE SCLEROSIS CURRENT STATUS AND STRATEGIES FOR THE FUTURE ppt
... MULTIPLE SCLEROSIS CURRENT STATUS AND STRATEGIES FOR THE FUTURE Janet E Joy and Richard B Johnston, Jr., Editors Committee on Multiple Sclerosis: Current Status and Strategies for the Future Board ... Medicine The members of the committee responsible for the report were chosen for their special competencies and with regard for appropriate balance Support for this project was provided by the National ... on Multiple Sclerosis: Current Status and Strategies for the Future and are not necessarily those of the funding agencies Additional copies of this report are available for sale from the National...
Ngày tải lên: 23/03/2014, 06:20
Brazil''''s Capital Market: Current Status and Issues for Further Development pot
... Western Hemisphere Department Brazil’s Capital Market: Current Status and Issues for Further Development Prepared by Joonkyu Park* Authorized for distribution by Vikram Haksar September 2012 This ... and steps for further development It starts by taking stock of the current status of local capital markets in Brazil, including in terms of size, investor base, maturity structure, both for the ... Report for Capital Markets (São Paulo) , 2012, Statistical Report for Asset Management (São Paulo) BNDES, 2011, Annual Report for 2010 (Rio de Janeiro) , 2010, Annual Report for 2009...
Ngày tải lên: 23/03/2014, 12:21
báo cáo hóa học:" The psychological context of quality of life: a psychometric analysis of a novel idiographic measure of bladder cancer patients’ personal goals and concerns prior to surgery" pot
... used bladder cancer disease specific instruments only, five used general instruments only (not specific to bladder cancer) , and five studies used a combination However, only one of the bladder cancer ... Kettering Cancer Center patients with bladder cancer were identified in the clinic and approached for participation The Eligibility criteria included: patients diagnosed with bladder cancer and ... relevant aspects of life HRQOL research on patients with bladder cancer is urgently needed, as bladder cancer is the fifth most commonly diagnosed cancer with an estimated 70,980 new cases in 2009 in...
Ngày tải lên: 20/06/2014, 15:20
BLADDER CANCER – FROM BASIC SCIENCE TO ROBOTIC SURGERY ppt
... Biology and Bladder Cancer Chapter Bladder Cancer Biology Susanne Fuessel, Doreen Kunze and Manfred P Wirth Part Epidemiology, Biomarkers and Prognostic Factors Chapter Biomarkers of Bladder Cancer ... and Bladder Cancer Bladder Cancer Biology Susanne Fuessel, Doreen Kunze and Manfred P Wirth Department of Urology, Technical University of Dresden Germany Introduction At present, bladder cancer ... in transitional cell bladder cancers: is it a good predictor for tumor behavior? Int Urol Nephrol, Vol.35, No.2, pp 181-188 26 Bladder Cancer – From Basic Science to Robotic Surgery Dominguez,...
Ngày tải lên: 27/06/2014, 13:20
Báo cáo y học: "The current status of targeting BAFF/BLyS for autoimmune diseases" pps
... act as a sink for BAFF and prevent its binding to BAFF-R TACI and BCMA also bind APRIL (for ‘a proliferationinducing ligand’), a molecule homologous to BAFF, which is not necessary for normal B ... survival [12,16] To further complicate matters, APRIL and BAFF can form heterotrimers [17] and the extracellular domain of APRIL can form a hybrid molecule with the intracellular domain of TWEAK (TWE-PRIL; ... of BAFF for the survival of established memory cells or of long-lived plasma cells is not yet certain 198 Available online http://arthritis-research.com/content/6/5/197 Table List of current...
Ngày tải lên: 09/08/2014, 01:24
báo cáo khoa học: "A role of 18F-fluorodeoxyglucose positron emission/computed tomography in a strategy for abdominal wall metastasis of colorectal mucinous adenocarcinoma developed after laparoscopic surgery" pptx
... metastasis after laparoscopic surgery for CRC is rare, reported as 0.71-1% in the literature [11-16] Recently the rate was reported as 1.3% in a randomized clinical trial by the Colon Cancer Laparoscopic ... Påhlman L, Cuesta MA, Msika S, Morino M, Lacy A, Bonjer HJ: Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randmised cilinical trial Lancet Oncol ... CLASSIC trial of laparoscopically assisted versus open surgery for colorectal cancer Br J Surg 2010, 97:1638-1645 Symonds DA, Vickery AL: Mucinous carcinoma of the colon and rectum Cancer 1976, 37:1891-1900...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo khoa học: "Comparison of intraoperative frozen section analysis for sentinel lymph node biopsy during breast cancer surgery for invasive lobular carcinoma and invasive ductal carcinoma" docx
... [5,7,8,10,11,13-15,17], including our own current series in which the false negative rate of frozen section analysis for SLN biopsy was 33% for ILC, 25% for IDC, and 30% for all breast cancer cases This particular ... frozen section analysis for confirming the presence of metastatic disease within SLNs during breast cancer surgery for ILC and IDC Methods Patient selection This study was performed under an established ... statistically significant difference in the false negative rate for frozen section analysis for SLN biopsy for ILC as compared to IDC (33% for ILC, 25% for IDC, P = 0.385) Although this may initially seem...
Ngày tải lên: 09/08/2014, 04:21
Báo cáo khoa học: "Laparoscopic insertion of pelvic tissue expander to prevent radiation enteritis prior to radiotherapy for prostate cancer" pdf
... use prior to radiotherapy for rectal cancer [9] Many reported cases involved the use of large tissue expanders for patients requiring post-operative adjuvant radiotherapy for large retroperitoneal ... particularly suitable during open colorectal surgery where mobilisation of the omentum off the colon is required But this procedure is difficult to perform laparoscopically, and in the thin patient, ... man with prostate cancer Opaque planning fiducial marker visible in prostate with adjacent loops of small bowel within the planned radiation field Figure Four incisions used for laparoscopic insertion...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "Intensity modulated radiotherapy for elderly bladder cancer patients" potx
... that RT given concurrently with or without chemotherapy provided benefits for locally advanced bladder cancer patients [29] For elderly patients with locally advanced bladder cancer, several reports ... IMRT and HT are feasible for elderly patients with locally advanced bladder cancer RT concurrent with chemotherapy, or alone, provides benefits for locally advanced bladder cancer patients However, ... the 5-year OS rates for patients with bladder cancer were 70% for T2 disease and 51% for T3 disease Shipley [36] also noted that the 5-year actuarial overall survival rates for T2 and T3-T4a were...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "Upfront systemic chemotherapy and preoperative short-course radiotherapy with delayed surgery for locally advanced rectal cancer with distant metastases" ppt
... integrating × Gy with delayed surgery Surgery was performed for nine patients R0 resection was achieved for six of the nine patients Subsequent metastatic surgery was possible for two of the patients ... after surgery for different preoperative radiotherapy regimens (5 × Gy and immediate surgery versus × Gy and delayed surgery versus conventional fractionated 50 Gy and delayed surgery) For patients ... respectively [2] Currently, this short-course RT schedule with immediate surgery is a widely accepted standard treatment for rectal cancer However, it is increasingly clear that MRF status, as determined...
Ngày tải lên: 09/08/2014, 09:21
Báo cáo y học: "Clinical significance in the number of involved lymph nodes in patients that underwent surgery for pathological stage III-N2 non-small cell lung cancer" pot
... of the patients was 51.0% for single lymph node positive, 58.9% for lymph nodes positive, 34.2% for lymph nodes positive, 30.0% for lymph nodes positive, and 20.4% for more than lymph nodes positive ... E: Cancer statistics, 2010 CA Cancer J Clin 2010, 60:277-300 Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 Int J Cancer ... lymph node positive patients was 51.0%, 58.9% for lymph nodes positive, 34.2% for lymph nodes positive, and 30.0% for lymph nodes positive, and 20.4% for more than lymph nodes positive (Figure 3)...
Ngày tải lên: 10/08/2014, 09:22
báo cáo khoa học: "Current status of haploidentical stem cell transplantation for leukemia" pps
... CY/MeCCNU/ATG CSP/MMF/ MTX short 1.8 220 Not done 55% 47% 2-year 19% for SR 31% for HR 12% for SR 39% for HR 2-year 68% for SR 42% for HR Japan, 2006[39] Journal of Hematology & Oncology 2008, 1:27 ... 0.06(M) 0.09(P) 0.01 (M+P) Ex vivo CD34+ selection 13% II~IV 21% 35% 47% 22 %for SR 79 %for HR 5-year 39% for SR 5% for HR Tuebingen, Germany 2004[22] AML/ALL/ others 63 TBI or BuExtensive based ... carried out for more than 20 years Early practice by Fred Hutchinson Cancer Research Center[10] demonstrated the promise and limitation of haploidentical HSCT for leukemia The overall survival for patients...
Ngày tải lên: 10/08/2014, 22:20