l methionine and its potential effects for cancer therapy
3 carbon isotope discrimination in roots and shoots of major weed species of southern u s rice fields and its potential use for analysis of rice–weed root interactions
... samples containing 87% soil Thus, its influence on sample d13C values will be minor except at low sample C fraction levels Corrected d13C values closely paralleled those for the Figure d13C levels ... to Howard Black for his invaluable technical assistance and statistical analyses; Gordon Miller, Jim Gignac, and Kenneth Hale for plant sampling, cleaning, and grinding; and Erik Pollock, University ... distinctively high d13C levels and the resulting large d13C differential with rice, yellow nutsedge, and perhaps crabgrass may be especially well suited to 13C discrimination studies, and potentially...
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Báo cáo khoa học: Hyaluronan–CD44 interactions as potential targets for cancer therapy pptx
... Proposed model for the cross-talk between tumor cells (epithelial cells) and tumor-associated stromal myofibroblasts Cancer cells and stroma-derived fibroblasts influence each other’s development The ... fibroblasts, myofibroblasts, neutrophils ⁄ eosinophils ⁄ basophils ⁄ mast cells, T ⁄ B lymphocytes, natural killer cells and antigen-presenting cells, such as macrophages and dendritic cells [4] The microenvironment ... of the pericellular matrix These complexes increase the viscoelastic nature of the pericellular matrix, creating a highly malleable extracellular environment that supports the cell shape change...
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Báo cáo y học: " Preparation of RGD-modified Long Circulating Liposome Loading Matrine, and its in vitro Anti-cancer Effects"
... inhibitory effects of RGD-M-LCL and RGD-LCL on Bcap-37 cells Bcap-37 cells were treated with various concentrations of RGD-LCL and RGD-M-LCL (equivalent to the same concentration of RGD-LCL) for 48h, and ... RGD-M-LCL and RGD-LCL were re-dissolved with DMEM or RPMI1640 after freeze-drying Effects of RGD-M-LCL on cell viability using MTT) assay Briefly, cells (5×103 per well) were seeded in 96-well plates ... equivalent to the same dose of RGD-LCL strongly inhibited the growth of the cancer cells However, in the cells treated with 1.25 mg/mL or 2.5 mg/mL of RGD-LCL, RGD-LCL itself was moderately cytotoxic...
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Báo cáo y học: "New role for Agrin in T cells and its potential importance in immune system regulation" ppsx
... LGL EL LGL Secreted form SS NtA FL FL FL FL FL FL FL FL LE LE FL S/T SAE S/T EL LGL EL EL LGL A/y SS: secretion signal TM: transmembrane domain FL: Follistatin-like domain NtA: amino-terminal ... and Kabouridis Arthritis Research & Therapy 2010, 12:205 http://arthritis-research.com/content/12/2/205 Page of Transmembrane form TM FL FL FL FL FL FL FL FL LE LE FL S/T SAE S/T EL LGL EL EL ... in our knowledge regarding the function of Agrin in T cells and the immune system in general, at both the molecular level and at the level of the whole organism At the molecular level important...
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Insights into the mechanism of safingol and its potential to synergize with anti cancer drugs
... generally small, short-lived and highly reactive molecules Specifically, O2·- and OH· are extremely unstable whereas H2O2 are freely diffusible and relatively long-lived (65) 24 1.3.1 Biological ... bioactive lipids, the role of sphingolipids in cell survival and cell death will be illustrated using S1P and ceramide as the examples, respectively 1.4.1 Sphingolipids and cell survival Upon the addition ... leads to cell death 1.3.2.1 ROS and cell survival Although traditionally, ROS are considered as toxic by-products, their role as intracellular signaling molecules in deciding the fate of cells...
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Tài liệu Economic Reforms, Foreign Direct Investment and its Economic Effects in India pdf
... analyses according to which the growth implications depend on various factors, including absorptive capacity and local skills, technological spillovers and linkages between foreign and local firms, ... for Globalisation In: C Tisdell (ed.), Globalisation and World Economic Policies: Effects and Policy Responses of Nations and their Groupings New Delhi (Serials Publ.): 644-658 Aizenman, J., and ... production, local R&D has gained in significance by still more than transfers of foreign technology This applies to all industries for which data are available Yet local R&D is concentrated in exactly...
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Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf
... Data collection ˚ Resolution (A) Mean I ⁄ r (I)a No of reflections Measure Unique Completeness (%)a Rmerge (%)a,b Overall Highest-resolution shell Lowest-resolution shell Multiplicitya Unit-cell constants ... contrast, Bacillus glutaminase ˚ shows relatively large displacement (average, 0.42 A; ˚ ) The small conformational change is a SD, 0.37 A possible explanation for the salt-tolerant glutaminase ... (2003) Crystallization and preliminary X-ray crystallographic studies of salt-tolerant glutaminase from Micrococcus luteus K-3 Acta Crystallogr D Biol Crystallogr 59, 566–568 33 Leslie AGW (1992)...
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accounting ethics and its important role for reduction of accounting fraud an empirical study in hanoi
... strictly as well as the professional in the field of medicine and law With respect of customer, “they also want to receive the service of accounting professional not only rely on his skill and ability, ... cannot use information for personal advantage Professional Behavior: A professional accountant should follow the relevant laws and regulations and should avoid any action that discredits the profession ... we may face with problem to have any resources for upgrade and grow as well as cannot have a comfortable life In reality, money and standard of value also go together and help out have anything,...
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accounting ethics and its impotant role for reduction of accounting fraud an empirical in hanoi
... In this section, all information is collected and calculated, which help explaining and proving the objectives of research The result will be overall picture about the problems of accounting ... efficiency and reliability, only when all of above factor and even the smallest details are to be set uniform, consistent, and reasonable In fact, many people not realize the importance of professional ... LIST OF TABLE Figure 1: activities and situations on holding potential for conflicts of interest for public official 19 Figure 4: external activities and situations on holding potential...
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Báo cáo khoa học: Ubiquitination of E3 ubiquitin ligase TRIM5a and its potential role pdf
... characterize the molecular function of TRIM5a and its regulator Results TRIM5a and Ro52 are phylogenetically and structurally similar On human chromosome 11p15, the trim5 gene is located with a cluster of ... et al (50 lm) or MG132 (20 lm) The cells were further cultured at 37 °C with the proteasome inhibitor for h The cells were then harvested, and the total cell lysates were prepared for TALON-bead ... (lanes and 2), FLAG–YopJ (wild-type) (lanes and 4) or FLAG-tagged YopJ mutant with a single substitution (C172S) (lanes and 6) was also coexpressed The cells were lysed in M guanidine hydrochloride...
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recombinant antibodies for cancer therapy, methods and protocols
... P., Delwail, V., et al (2001) Rituximab (anti-CD20 monoclonal antibody) as single first-line therapy for patients with follicular lymphoma with a low tumor burden: clinical and molecular evaluation ... of a molecule in the body Molecules with low molecular weights undergo ultrafiltration from the plasma in the glomerulum of the kidney The passage of molecules across the glomerular filtration ... Ritz, J., Pesando, J M., Sallan, S E., Clavell, L A., Notis-McConarty, J., Rosenthal, P., and Schlossman, S F (1981) Serotherapy of acute lymphoblastic leukemia with monoclonal antibody Blood 58,...
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Báo cáo hóa học: " Research Article High-Quality Time Stretch and Pitch Shift Effects for Speech and Audio Using the Instantaneous Harmonic Analysis" pdf
... possible to calculate filter impulse responses aligned to the fundamental frequency contour Central frequency of the filter band is calculated as the instantaneous frequency of fundamental multiplied ... (11) The Hilbert transform and DESA can be applied only to monocomponent signals as long as for multicomponent signals the notion of a single-valued instantaneous frequency and amplitude becomes ... they are in reality It is possible to determine the filter bandwidth as a threshold value that gives desired level of accuracy The threshold value depends on length of analysis window and type of...
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Báo cáo hóa học: " Research Article An Efficient Addressing Scheme and Its Routing Algorithm for a Large-Scale Wireless Sensor Network" pptx
... consists of 16 bits and is partitioned equally, every dimension will have the range of and 255 Similarly, two address dimensions may be arbitrarily allocated—say, 10 bits for x-axis and bits for y-axis ... systematically determine the segment of address space that will be allocated to a new node Therefore, it will also be acceptable for a parent (including ZC) to have grandchildren before the address ... once a cluster is formed, one of nodes in the cluster is periodically elected as a cluster header randomly and probabilistically to shred energy load among the nodes evenly Then, the chosen cluster...
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Báo cáo vật lý: "Immobilization of Dithizone onto Chitin Isolated from Prawn Seawater Shells (P. merguensis) and its Preliminary Study for the Adsorption of Cd(II) Ion" pdf
... selective, especially when alkali and alkali-earth metal ions are also available in the solution in high level of concentrations Therefore, modification of the chitin surface should be carried out ... be very selective for Hg, Cd and Pb.18–19 The immobilization of dithizone onto the surface of polymer16 and silica gel17 has been reported and successfully used for the removal and selective pre-concentration ... a 500 ml flask The mixture was refluxed and stirred for 2, 4, and h at 70oC The product was filtered and washed consecutively with toluene, ethanol and water several times until the filtrate...
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Báo cáo khoa học: "Capsular polysaccharide typing of domestic mastitis-causing Staphylococcus aureus strains and its potential exploration of bovine mastitis vaccine developmen" docx
... 109 live bacteria The suspension of 109 bacterial cells per ml were heated for 30 at 100oC to kill the bacteria and then sonicated for For the agglutination test, 25 l of the staphylococcal suspension ... rigid cell wall, it is lost rapidly in artificial media during culture Lee et al [24] reported that staphylococci grown on surfaces, both in vitro and in vivo, produce large quantities of cell-associated ... mastitis milk in Korea We also describes the methodology for the purification process of the CP from clinical isolates Materials and Methods Bacteria and media A total of 107 isolates collected from...
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Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis pdf
... superior and longer-lasting anti-inflammatory effects compared with free Dex, consistent with its selective accumulation, retention, and pH-sensitive drug release (extracellular and intracellular) ... Materials HPMA [27], MA-FITC (N-methacryloylaminopropyl fluorescein thiourea) [28], N-methacryloylglycylglycine (MA-Gly-Gly-OH) [29], and N, N-dioctadecyl-N', N'-bis(2-hydroxyethyl)propanediamine (LA) ... Holbrook, NY, USA) removal of the solvent, the isolated samples were dissolved in acetonitrile/water (1:1, vol/vol, 600 l) for high-performance liquid chromatography (HPLC) analysis An Agilent...
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Báo cáo y học: "Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic study" pptx
... malignancies Abbreviations NSCLC: non-small cell lung carcinoma; LCNEC: large cell neuroendocrine carcinoma; LCC: large cell carcinoma; SCLC: small cell lung carcinoma; CSC: cancer stem cell; LC: ... (GO) analysis, highlighting their biological and molecular functions and cellular localization As Figure shows, the molecular functions and cellular localization of proteins preferentially expressed ... offered clinical samples from patients HO and TN pathologically diagnosed all samples independently TO and NI supported us clinically and financially NG supported us experimentally and financially...
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MECHANISM OF TISSUE TRANSGLUTAMINASE UPREGULATION AND ITS ROLE IN OVARIAN CANCER METASTASIS
... NK cells Natural killer cells NLS Neuclear localization signal NOSE Normal ovarian surface epithelial cells OC Ovarian cancer OCICs Ovarian cancer initiating cells OPN Osteopontin PAI Plasminogen ... tumor, cancer cells undergo epithelial-mesenchymal transition (EMT) to lose their epithelial characteristics, including their apical-basal polarity and specialized cellcell contacts, and acquire ... fibronectin and integrins not only promotes cancer cell adhesion and migration, but also promotes cancer cell proliferation and survival by upregulating cell survival and anti-apoptotic signaling 20...
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Đồ án tiếng anh AN ENGLISHVIETNAMESE CROSSCULTURAL COMMUNICATION STUDY ON USING ADDRESSING FORM AND ITS POTENTIAL CULTURE SHOCK
... the following table and table 4: 30 Table 3: Lineal relations Relation to addresser English term Vietnamese term paternal grandfather grandfather Ông nội paternal grandmother maternal grandfather ... advisor and colleague that always finds the time for listening to the little problems and roadblocks that unavoidably crop up in the course of performing research Her technical and editorial advice ... social status and marital status, English titles Here are the formal titles English speakers use: Sir (adult male of any age) Ma'am (adult female - North American) Madam (adult female) 39 Mr + last...
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