kie apos s as probes of transition state structure

Báo cáo khoa học: Homoadenosylcobalamins as probes for exploring the active sites of coenzyme B12-dependent diol dehydratase and ethanolamine ammonia-lyase docx

Báo cáo khoa học: Homoadenosylcobalamins as probes for exploring the active sites of coenzyme B12-dependent diol dehydratase and ethanolamine ammonia-lyase docx

... substrate (‘distal’ conformation) Stick model represents the adenosyl group of AdoCbl Residue numbers in the a subunit (B) Partial structures of AdoCbl analogues used in this study R represents ... functions of homoadenosylcobalamins M Fukuoka et al A B Fig Modeling studies of diol dehydratase on adenosyl radical formation and access to substrate (A) and partial structures of AdoCbl analogues ... functions of homoadenosylcobalamins cob(II)alamin and substrate radicals are closer than that of diol dehydratase Experimental procedures Materials Partial structures of the coenzyme analogues used...

Ngày tải lên: 07/03/2014, 21:20

10 444 0
Directors of Central Intelligence as Leaders of the U.S. Intelligence Community 1946 - 2005 potx

Directors of Central Intelligence as Leaders of the U.S. Intelligence Community 1946 - 2005 potx

... months as president His assistant Clark Clifford has testified that this complaint increased as he moved toward mak4 The British officer who served as Gen Eisenhower s senior intelligence adviser ... revising his reasoning and conclusions Other members of CIA s History Staff also contributed in many ways Dr David Robarge s thorough, classified biography of John McCone as DCI served as both a source ... that arose in subsequent decades, perhaps when Clifford served as a consultant to various presidents, as secretary of defense, or even later 16 Truman s memoir, which stresses the DCI s role in...

Ngày tải lên: 22/03/2014, 21:20

356 308 0
The State of Marketing 2011: Unica’s Annual Survey of Marketers pptx

The State of Marketing 2011: Unica’s Annual Survey of Marketers pptx

... asking marketers about their key issues, this year s survey changed one of the answer options on the questionnaire from “measuring results and increasing effectiveness” to “attributing success ... Analysis and Action – This year, “measurement, analysis and learning” overtook “IT support of marketing needs” as the #1 marketing bottleneck And after years of analysis paralysis, respondents identified ... TECHNOLOGY Measurement, Analysis & Learning Overtakes IT as the Most Pervasive Bottleneck This year, “measurement analysis & learning” moved into the lead spot as the biggest bottleneck marketers face...

Ngày tải lên: 23/03/2014, 04:21

29 409 0
Cinema as Art and Philosophy in Béla Tarr''''s Creative Exploration of Reality potx

Cinema as Art and Philosophy in Béla Tarr''''s Creative Exploration of Reality potx

... the necessary tension; the professional non-actors, actor-mediums, capable of living Description is used here in relation to Deleuze 's idea of description as process of creating and erasing the ... bottomlessness, and that perhaps is, as Jonathan Romney argues, essentially Tarr 's invitation to the viewer (Romney 2003) At the bottomlessness sensations are born and change is made possible ... faces, architextures of settings, and sound Like the spider web of interwoven pieces of a non-told story, it is an image of time reected now in the long shot of beer glasses or in the slow scanning...

Ngày tải lên: 23/03/2014, 11:21

10 420 0
Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part1 potx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part1 potx

... by the Legislature Under its assigned missions, the office conducts the following types of examinations: Financial audits attest to the fairness of the financial statements of agencies They examine ... benefits Such bills cannot be enacted unless they are referred to the Office of the Auditor for an assessment of the social and financial impact of the proposed measure Analyses of proposed special ... The Office of the Auditor The missions of the Office of the Auditor are assigned by the Hawaii State Constitution (Article VII, Section 10) The primary mission is to conduct post audits of the...

Ngày tải lên: 20/06/2014, 02:20

10 316 0
Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part2 pot

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part2 pot

... Coordinator Budget Fiscal Officer Project Manager Tourism Specialist Administrative Assistant II Secretary II Administrative Assistant I Source: Hawai`i Tourism Authority This is trial version www.adultpdf.com ... Revenues and Appropriations, FY1999-2000 to FY2001-02 FY1999-2000 Revenues: Tourism Special Fund Interest/miscellaneous receipts Total revenues Appropriations: Regular session Special session Total ... Tourism Authority adequately manages its major contracts Assess the compliance of major contractors with contract provisions and the propriety of contract expenditures Make recommendations as appropriate...

Ngày tải lên: 20/06/2014, 02:20

10 365 0
Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part3 ppt

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part3 ppt

... provided little oversight and no constraints on the amounts of HVCB employees’ salaries As a result, HVCB salaries and bonuses increased significantly after the authority assumed responsibility from ... questionable expenditures of state contract funds, such as purchasing an office Christmas tree and spending over $100 for less than a pound of coffee for office use, they not appear to be widespread ... holiday parties, or other occasions • State funds were used to pay for $93 in napkins and refreshments for two HVCB office blessings • Gifts valued in excess of $800 were purchased for HVCB s outgoing...

Ngày tải lên: 20/06/2014, 02:20

10 362 0
Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part4 potx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part4 potx

... Bennet and Associates two separate amounts under two separate agreements leads us to question whether use of HVCB as the pass-through entity for payment was designed to evade the State Procurement ... was also suspect for other reasons First, we found that HVCB used state contract funds to pay some of the invoices it received from the governor s office because it had not yet received funds ... finance/public ethics law issues as they relate to dues for a particular political candidate, research regarding gifts of travel to public officials, state ethics law issues, and drafting HVCB testimony...

Ngày tải lên: 20/06/2014, 02:20

10 317 0
Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part5 pptx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part5 pptx

... authority s contract procurement methods and assigns responsibility of overseeing the procurement steps to various sections It also specifies that overall responsibility for a contract rests with the section ... These financial statements are the responsibility of HVCB s management Our responsibility is to express an opinion on these financial statements based on our audit The financial statements of ... statements are free of material misstatement An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements An audit also includes assessing...

Ngày tải lên: 20/06/2014, 02:20

10 357 0
Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part6 potx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part6 potx

... net assets of HVCB and changes therein are classified and reported as follows: Unrestricted Net Assets - Net assets not subject to donor-imposed stipulations Temporarily Restricted Net Assets - ... 2003 Description of Financial Statements Statements of Financial Position (Exhibit 3.1) These statements present the assets, liabilities, and net assets of HVCB at December 31, 2002 and 2001 Statements ... Net assets subject to donor-imposed stipulations that may or will be met either by actions of the HVCB and/ or the passage of time (b) Cash equivalents For purposes of the statements of cash flows,...

Ngày tải lên: 20/06/2014, 02:20

10 292 0
Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part7 docx

Management and Financial Audit of the Hawai`i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawaii Report No. 03-10 June 2003_part7 docx

... This is trial version www.adultpdf.com Responses of the Affected Agencies Comments on Agency Responses We transmitted drafts of this report to the Board of Directors of the Hawai‘i Tourism Authority, ... the State and Legislature take appropriate steps to further assess HVCB s violation of generally accepted accounting principles 56 This is trial version www.adultpdf.com This is trial version ... authority s efforts to address some of the concerns raised in a prior audit They also noted their support for our audit as a tool to improve its operations, respond to legislative questions and concerns,...

Ngày tải lên: 20/06/2014, 02:20

9 248 0
Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part1 pptx

Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part1 pptx

... by the Legislature Under its assigned missions, the office conducts the following types of examinations: Financial audits attest to the fairness of the financial statements of agencies They examine ... benefits Such bills cannot be enacted unless they are referred to the Office of the Auditor for an assessment of the social and financial impact of the proposed measure Analyses of proposed special ... demonstrate the effectiveness of its activities and programs Industry experts attest to the complexity and difficulty in assessing the effectiveness of tourism development efforts such as promoting...

Ngày tải lên: 20/06/2014, 02:20

10 268 0
Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part2 potx

Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part2 potx

... to state general excise taxes Exhibit 1.3 summarizes HTA s audited revenues and expenditures for all funds for the past three fiscal years The authority s financial statements are comprised of ... tourism in a sustainable manner consistent with our economic goals, cultural values, preservation of natural resources, community desires and visitor industry needs The authority is responsible ... levied on gross rental income from hotel rooms, suites, condominiums, and vacation houses Generally, the TAT applies to rentals by nonresidents for less than 180 consecutive days It is collected...

Ngày tải lên: 20/06/2014, 02:20

10 240 0
Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part3 doc

Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part3 doc

... its activities and those of its contractors Evaluate the adequacy of HTA s measures of effectiveness in providing a basis for performance assessments and an assurance that taxpayers receive value ... Without a strategic plan of its own that maps out the long-term goals and processes to assess the accomplishments of its major contractors, the authority s board of directors is unable to demonstrate ... out its mission We also noted that performance indicators for the tourism industry, such as statewide visitor spending, were insufficient measurements given the problems raised by other states Our...

Ngày tải lên: 20/06/2014, 02:20

10 222 0
Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part4 doc

Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part4 doc

... survey measures states of mind, rather than the number of visitors who visited Hawai‘i in response to a contractor s efforts, also known as conversion rates Second, the survey s results are subject ... values for each of these measures, and the self-assessment provides no information on the changes achieved as a result of the contractor s efforts The authority solicits selected stakeholders’ ... transactions reported to and relied on by HTA Separation of duty, a key concept of internal controls, demands the disseminating of tasks and associated privileges for sensitive business processes...

Ngày tải lên: 20/06/2014, 02:20

10 154 0
Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part5 doc

Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part5 doc

... issue remains: the authority s planning processes and its assessment of marketing efforts continue to be largely based on conjecture and opinion with no objective measures of success or failure ... original schedule governing the scope of services instead of the compensation schedule in at least four cases; erroneous budget amounts, such as a $145,000 discrepancy when the amount spelled ... rental rates but can also involve the provision of goods and services Contractual agreements between the center and its clients specify the discounts, as well as the goods and services SMG will...

Ngày tải lên: 20/06/2014, 02:20

10 184 0
Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part6 docx

Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part6 docx

... This is trial version www.adultpdf.com This is trial version www.adultpdf.com This is trial version www.adultpdf.com This is trial version www.adultpdf.com This is trial version www.adultpdf.com ... trial version www.adultpdf.com This is trial version www.adultpdf.com This is trial version www.adultpdf.com This is trial version www.adultpdf.com This is trial version www.adultpdf.com ...

Ngày tải lên: 20/06/2014, 02:20

10 180 0
Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part7 ppt

Management and Financial Audit of Hawai‘i Tourism Authority’s Major Contracts A Report to the Governor and the Legislature of the State of Hawai‘i_part7 ppt

... use of performance measures is not limited to broad, agencylevel activities Measures are useful for planning for and assessing performance of many programs, initiatives, or projects, even of staff ... of the effect of its deployment of state resources We discuss this issue in our report with reference to performance reporting standards promulgated by the Destination Marketing Association International ... expertise While HTA s response lists available measures, such not appear in its plans, contracts, or reports to the public and the Legislature to provide a meaningful before and after comparison of...

Ngày tải lên: 20/06/2014, 02:20

8 177 0
OFFICE OF THE STATE AUDITORPHIL BRYANTAUDITORINDEPENDENT AUDITOR''''S SINGLE AUDIT REPORT ON ppt

OFFICE OF THE STATE AUDITORPHIL BRYANTAUDITORINDEPENDENT AUDITOR''''S SINGLE AUDIT REPORT ON ppt

... Members of the Board of Supervisors Alcorn County, Mississippi We have audited the primary government financial statements of Alcorn County, Mississippi, as of and for the year ended September 30, 1996, ... express such an opinion The results of our procedures and our audit of the primary government financial statements disclosed an immaterial instance of noncompliance with state laws and regulations ... auditing standards and the procedures prescribed by the State Auditor, and accordingly, included such tests of the accounting records and such other auditing procedures as we considered necessary...

Ngày tải lên: 20/06/2014, 02:20

7 185 0
báo cáo hóa học:" Assessing normative cut points through differential item functioning analysis: An example from the adaptation of the Middlesex Elderly Assessment of Mental State (MEAMS) for use as a cognitive screening test in Turkey" docx

báo cáo hóa học:" Assessing normative cut points through differential item functioning analysis: An example from the adaptation of the Middlesex Elderly Assessment of Mental State (MEAMS) for use as a cognitive screening test in Turkey" docx

... MEAMS subtests requiring adjustment of pass scores by ANOVA and Rasch analysis Bold numbers indicate adjusted scores Subtest Score range Pass score in original version Turkish Pass Scores (where ... sub-tests each of which has a 'pass score' (Table 2) A screening score of either (fail) or (pass) is assigned to each subtest These subtests are sensitive to the functioning of different areas of ... for scales measuring aspects of cognitive impairment One such scale, the Middlesex Elderly Assessment of Mental State (MEAMS) was developed as a screening test to detect gross impairment of specific...

Ngày tải lên: 20/06/2014, 15:20

8 448 0
w