k and na channels

... Ca and K channels (74) Voltage-gated K+ Channels Of the many K+ channels expressed in the coronary circulation, i.e Ca2+activated (KCa), ATP-sensitive (KATP), and inwardly rectifying (Kir) K+ channels, ... 2-adrenergic receptor; α1 and α2, + + α-adrenergic receptors; KCa, calcium-sensitive K channel; KATP, ATP-sensitive K K channel; KV, voltage+ sensitive K channel Receptors, enzymes, and channels are indicated ... indicate that protein kinase C (PKC) also contributes to the coronary myogenic response through alterations in CaV1.2 (214) In addition to PKC, protein kinase A and protein kinase G are also prominent...

Ngày tải lên: 24/08/2014, 11:10

... Material and methods Human tissue kallikrein was used as reference to calculate (kcat/Km)/(kcat/Km)ref N-BK peptide C-BK peptide Enzyme kcat/Km(mM)1Æs)1) kcat/Km)/(kcat/Km)ref Km(lM) hK1 Cat L Cat K ... produces BK(5–9) from BK and Lys-BK, and suggests that cathepsin K is a new member of the kininase family Both the kininogenase activity of cathepsin L and/ or the kininase activity of cathepsin K may ... with C-BK peptide (20 lM final), plus hK1 (2 nM) and cathepsins L (0.2 nM), K (2 nM) and B (2 nM) Kallikrein hK1 (5 nM) and cathepsins L (0.5 nM), K (5 nM) and B (5 nM) were incubated with BK-peptide...

Ngày tải lên: 31/03/2014, 07:20

... břízy karpatské Vápnění zvýšilo půdní reakci, obsah půdních bází, nasycení sorpčního komplexu bázemi, kationtovou sorpční výměnnou kapacitu a redukovalo koncentraci pohyblivého hliníku Na druhou ... Scandinavian Journal of Forest Research, 14: 51–63 Braekke F.H., 1999b Drainage, liming and fertilization of organic soils II Distribution of macroelements and heavy-metal accumulation Scandinavian ... Zprávy lesnického výzkumu, 50: 75–77 Slodič k M et al., 2005 Lesnické hospodaření v Jizerských horách Hradec Králové, Jíloviště-Strnady, LČR, VÚLHM: 232 ÚRadníček L., Maděra P., Martínková M., 2001...

Ngày tải lên: 07/08/2014, 10:22

... 15 Nagase H, Kashiwagi M: Aggrecanases and cartilage matrix degradation Arthritis Res Ther 2003, 5:94-103 16 Lark MW, Bayne EK, Flanagan J, Harper CF, Hoerrner LA, Hutchinson NI, Singer II, Donatelli ... Carrageenan-induced gonarthritis studied in dogs Acta Orthop Scand 1990, 61:207-212 Gay RE, Neidhart M, Pataky F, Tries S, Laufer S, Gay S: Dual inhibition of 5-lipoxygenase and cyclooxygenases and by ML3000 ... Prostaglandins 1997, 54:689-698 Hansen ES, Fogh K, Hjortdal VE, Henriksen TB, Noer I, Ewald H, Herlin T, Kragballe K, Bunger C: Synovitis reduced by inhibition of leukotriene B4 Carrageenan-induced...

Ngày tải lên: 09/08/2014, 06:23

... Maldonado, and W P Kirk, “Low Schottky barriers on n-type silicon (001),” App Phys Lett., vol 83, pp 2593, 2003 [1.49] M Tao, D Udeshi, S Agarwal, E Maldonado, and W P Kirk, “Negative Schottky ... 1968 [1.16] C J Koeneke and W T Lynch, “Lightly doped Schottky MOSFET,” IEDM Tech Dig., pp 466, 1982 [1.17] T Mochizuki and K D Wise, “An n-channel MOSFET with Schottky source and drain,” IEEE ... Rosa, I J R Baumvol and J Morais, “Thermal stability of nitrided high -k dielectrics,” Physica Status Solidi A, vol 201, pp 870, 2004 [1.28] K Kita, M Sasagawa, K Tomida, K Kyuno and A Toriumi, "Oxidation-Induced...

Ngày tải lên: 14/09/2015, 14:04

... range of patients and controls were 44-85 year and 43-86 year respectively Table shows serum Na+ , K+ of case and control groups, with a significant difference in serum + Na of case and control ones ... cataract formation is serum Na+ level [34,35] Lens has high content of potassium and low content of sodium Lens K+ level is 125 mmol/kg of lens water and lens Na+ is 14-26 mmol/kg of lens water [36] ... concentration, can be known as a risk factor for cataract formation Na+ pump activity in lens is as in other cells and it is related to intracellular Na+ , extracellular K+ and eventually to serum...

Ngày tải lên: 03/11/2012, 09:49

... pyruvate kinase [32] and 1.45 mLÆmg)1Æcm)1 for lactate dehydrogenase [33] Results and discussion Comparative effect of Na+ and K+ on the activity of pyruvate kinase The effect of Na+ and K+ concentration ... higher selectivity between K+ and Mg2+ for their respective sites This is clearly evident in the ratios Ki Mg2+/KNa+, Ki Na+ /KMg2+ and Ki K+ /KMg2+ that are 24, 17 and 231, respectively The overall ... apparent binding energies of Na+ and K+ to pyruvate kinase (in 40% dimethylsulfoxide the DG°t and DG°b are )3.0 and )14.56 kJÆmol)1 for Na+ and )2.01 and )22.6 kJÆmol)1 for K+ ) We found that in presence...

Ngày tải lên: 08/03/2014, 02:20

... membrane enzyme Na /K- ATPase from inactivation by the heat shock protein a-crystallin Na /K- ATPase activity decreased upon incubation with fructose, H2O2 and methylglyoxal However, Na /K- ATPase activity ... Boonstra, J., Schamhart, D.H., de Laat, S.W & van Wijk, R (1984) Analysis of K+ and Na+ transport and intracellular contents during and after heat shock and their role in protein synthesis in rat hepatoma ... in Na+ or K+ Discussion The membrane protein Na /K- ATPase of red blood cell ghosts was stressed using externally applied fructose, methylglyoxal and H2O2 and activity measured by 86Rb uptake We...

Ngày tải lên: 17/03/2014, 03:20

... Shaker B K+ channels J Membr Biol 152, 49–56 47 Rogowski, R.S., Krueger, B .K. , Collins, J.H & Blaustein, M.P (1994) Tityustoxin Ka blocks voltage-gated noninactivating K+ channels and unblocks ... obtained for Shaker B (Fig 6B), rat Kv1.2 (Fig 6C), rat Kv1.1 and Kv1.3 channels (Fig 6D) The IC50 values of sPi4 were 3.0 ± 2.2 nM for Shaker B (n ¼ 45) and ± pM for rat Kv1.2 (n ¼ 55) channels, whereas ... the toxin to Kv-type channel recognition Finally, it will be interesting to test the sPi4 bioactivity on different classes of K+ channels (e.g Eag, HERG, KCNQ, Slo, IKCa, Kir, and KCNK) in order...

Ngày tải lên: 17/03/2014, 10:20

... p42/44 MAPK (also called ERK1/2) through the Ras/Raf/ MAPK kinase/MAPK cascade (where Raf is a MAPK kinase kinase and MEK is a MAPK kinase) [29,30] However, the activation of this cascade, unlike that ... Oguchi, A., Okada, K. , Ishikawa, S.-e., Saito, T., Kawakami, K. , Hara, Y & Shimada, K (1993) Regulation of Na ,K- adenosine triphosphatase gene expression by sodium ions in cultured neonatal rat cardiocytes ... of protein kinase C in the signal pathways that link Na+ / K+ -ATPase to ERK1/2 J Biol Chem 276, 42050–42056 32 Tian, J., Gong, X & Xie, Z (2001) Signal-transducing function of Na+ -K+ -ATPase is...

Ngày tải lên: 24/03/2014, 00:21

... Meliak Thanks for being there for countless lab bookings, taking weekend and early morning phone calls when equipment wasn’t working, always making time to teach me to use and set up equipment and ... in maintenance of force production and muscle contractility In skeletal muscle knockout α2 mice and partial α2 knockout mice (α2 reduced by ~50%) marked decreases in treadmill running and muscle ... membrane and may impair excitability (Sjøgaard et al., 1985; Sejersted & Sjǿgaard, 2000) The skeletal muscle Na+ , K+ -ATPase (NKA) enzyme counteracts the excitationinduced Na+ and K+ fluxes and thus...

Ngày tải lên: 04/12/2015, 13:59

... (Thornthwaite, 1948), the Blaney-Criddle method (Blaney and Criddle, 1950), the Makkink method (Makkink, 1957), and the Priestley and Taylor method (Priestley and Taylor, 1972) However, because these methods ... hydraulic conductivity and the transport of salts such as cations (Na+ , Ca2+, Mg2+ and K+ ) and Cl- in a column were investigated by using a tensiometer and a four-electrode sensor, and the amounts of ... 0.5 wt% and 1.0 wt% Alkali soil and gypsum were mixed uniformly and were packed in an acrylic ring with an outer diameter of 60 mm, inner diameter of 50 mm, and height of 20 mm at a bulk density...

Ngày tải lên: 05/09/2013, 09:38

... and Edward VIII were the highest numbered monarchs of England • Elvis Presley is called the king, which makes him the monarch of rock • Wal-Mart is the monarch of retail sales monopoly (muh NAH ... It’s traditional for teenagers to mock each others’ actions • Dottie mocked Dan by putting on a baseball cap at a cocked angle and speaking in her lowest vocal range • The castle mocked the invading ... afford his narcissistic nature, having hired six full-time servants to see to his every need [-ally adv., narcissism n.] narrative (NA ruh TIV) adj in story form; taking the nature of a narration;...

Ngày tải lên: 01/11/2013, 14:20

... kielbasa Polish; seasoned pork and beef sausage, may be smoked kieves Irish name for mash tuns kilderkin Cask for beer (18 gallons = 80.1 L) and ale (16 gallons = 71.2 L) Kiliani reaction Colorimetric ... human food kryptoxanthin See cryptoxanthin kuban See milk, fermented kudzu See kuzu kumiss See milk, fermented kumquat A citrus fruit Fortunella spp.; widely distributed in S China and now cultivated ... Bacillus subtilis and Propionobacterium spp Used in soups and stews kb Kilobase,a measure of the size of DNA and RNA by the number of thousands of bases in the sequence under consideration kcal Abbreviation...

Ngày tải lên: 21/01/2014, 14:20

... black and other immigrant mothers are much less likely to smoke or drink during pregnancy; less likely to smoke around their children; less likely to drink on a regular basis; and more likely ... Regression of Maternal Health Behaviors on Generational Status and Race/Ethnicity, FFS and MCS* Prenatal Prenatal Early Prenatal Smoking Drinking Breastfed around Child Binge Drinking Smoking Care (B) ... significantly more likely than U .K. -born white mothers to breastfeed (e.778), but no less likely than native whites to smoke or drink while pregnant, and no more likely to receive early prenatal care South...

Ngày tải lên: 12/02/2014, 12:20

... Classroom Washington, DC: National Academies Press 20.  National Research Council (2007) Taking Science to School Washington, DC: National Academies Press 21.  Ibid 22.  National Research Council ... understanding of ourselves and the universe, and to the reduction of hunger, disease, and poverty STEM experts also provide a wealth of knowledge that serves national security and protects our natural ... DR K- 12 research and development portfolio on instructional materials includes applied efficacy research—studies that look at how, for whom, why, and 67.  National Science Board (2000) National...

Ngày tải lên: 12/02/2014, 19:20

... weld lines on both the external and internal surfaces (Fig 8) compared to Fig • Improved quality prediction (Fig 9) • Further check on quality, cooling and sink marks was conducted Results indicated ... because the heat cannot be taken away uniformly from the mould and the different shrinkage causes warpage and cooling time increase (Fig 4) On the other hand, if the cooling channels can be made to ... on reviewing and evaluating the injection moulding process, to set the knowledge and background on the subject Then a study of proposed methods for developing and applying conformal channels is...

Ngày tải lên: 12/02/2014, 22:20

... VNU Journal of Science, Mathematics - Physics 23 (2007) 225-231 In the present work, we prepared LiF powders activated with Mg, Cu, Na and Si and studied the dependence of the glow curve and the ... mol%, Na: 1.8-2.0 mol% and Si: 1.8-2.0 mol% In the present work, we prepared LiF powder activated with Mg 0.2-1.0 mol%, Cu 0.2-1.0 mol%, NaSi 1.6-2.4 mol% (NaSi was considered as a single dopant and ... as total of Na and Si because the compound Na2 SiO3.9H2 O was added) The X-ray diffraction (XRD) patterns of four kinds of the above mentioned specimens were obtained by using Cu -K (λ = 0.154056...

Ngày tải lên: 13/02/2014, 04:20

... Tomita, M., Hashimoto, K. , Takahashi, K. , Shimizu, T., Matsuzaki, Y., Miyoshi, F., Saito, K. , Tanida, S., Yugi, K. , Venter, J.C., & Hutchison, C 58 Journal of Theoretical and Applied Information Technology ... Levin, J R., & Mayer, R E (1993) Understanding illustrations in text, in B .K Britton, A Woodward, and M Binkley (Eds.), Learning from Textbooks: Theory and practice Hillsdale, NL: Erlbaum Lin, ... curriculum followed by the Turkish Ministry of National Education As mentioned above, the curriculum covers chemistry, physics, biology and health within the framework of Science and Technology course...

Ngày tải lên: 14/02/2014, 13:20