is there a role for imaging in lung cancer screening
Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx
Ngày tải lên :
09/08/2014, 09:20
... DMe Alive DM Death DM Death DM Death DM Death DM Alive Out-come a Lateral, bMedial, cInvasive ductal carcinoma, dInvasive Paget’s disease, eDistance metastasis patients had lung metastasis and ... nodes in the infra or supraclavicular fossa or in the internal mammary chain was considered as a regional recurrence Any recurrence outside these areas was defined as DM Statistical Analysis LRR and ... clear surgical margins (>1 mm) Axillary lymph node staging was performed in all patients Pathological staging was reviewed based on AJCC 2002 The date of evaluation was January 2009 Patient-related...
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Báo cáo khoa học: "Bench-to-bedside review: Is there a place for epinephrine in septic shock" pptx
Ngày tải lên :
12/08/2014, 23:20
... correlating an increase in MAP with an increase in cardiac index [6] Using epinephrine as a first line agent, Moran et al [7] reported a linear relationship between epinephrine dosage and heart rate, ... does adrenaline have a role as a first-line inotropic agent? Anaesth Intensive Care 1992, 20: 470-474 Moran JL, O’Fathartaigh MS, Peisach AR, Chapman MJ, Leppard P: Epinephrine as an inotropic agent ... epinephrine (MAP and cardiac index increase) were obtained without the adjunction of dobutamine This may prove to be important from a practical standpoint in situations such as transportation Arrhythmia...
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Báo cáo khoa học: "Is there a place for N-acetylcysteine in the treatment of septic shock" pptx
Ngày tải lên :
12/08/2014, 20:20
... however, and there was also a significant increase in the cardiac index in the NAC-treated group [20] Conclusions This is an exciting time for intensivists involved in the care of patients with sepsis, ... microcirculation and thus oxygen extraction, while at the same time attenuating inflammatory responses Prostacyclin, a prostaglandin synthesized in endothelial cells, is a potent vasodilator and an inhibitor ... TNF-α and IL-6 and reduced the mortality rate in premature infants with sepsis [13] NAC in animal experimental and human sepsis NAC increases nitric oxide synthesis and cGMP Several studies have...
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Báo cáo y học: "Tranexamic acid in cardiac surgery: is there a cause for concern" pps
Ngày tải lên :
13/08/2014, 21:21
... patients not taking platelet active medication and having primary myocardial revascularisation This patient population appears not to have observed safety issues when tranexamic acid was administered ... study adds to the data questioning if tranexamic acid administration has a place in higher risk cardiac surgery and especially in surgery where a cardiac chamber is opened Competing interests In ... of aprotinin versus tranexamic acid in cardiac surgery Anesth Analg 2009, 110:21-29 Fodstad H, Forssell A, Liliequist B, Schannong M: Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid...
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Context based learning: A role for cinema in science education pdf
Ngày tải lên :
23/03/2014, 11:21
... conceptual language in reading, writing, problem solving and guiding practical action in the laboratory and also in daily life The Role of Cinema This paper discusses the role of cinema as a tool for ... and, not taking advantages of the real possibilities (Brake et al, 2003) 134 Context based learning: A Role for Cinema in Science Education An artistic manifestation, as audiovisual language, shows ... sense that it is primarily designed to be show in a public performance Whereas a dramatic play is realized as a live performance by actors on a stage, a movie is show in a cinema, not as a live...
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is there a future for quantum chemistry
Ngày tải lên :
02/06/2014, 09:45
... usually within physics and mathematics ˙ i hψ=Hψ Quantum Mechanics S = k log W Statistical Mechanics Computational Chemistry Computational chemistry is a branch of chemistry that uses principles ... to assist in solving chemical problems Quantum Mechanics Molelcular Orbital Theory Density Functional Theory Ab Initio Calculations Statistical Mechanics Molecular Dynamics Monte Carlo Transition ... levels important for charge localization and for electron injection dynamics I− Distribution at Interface I− Distribution at Interface • Solvent near interface cannot be described by single dielectric...
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Báo cáo y học: "Bench to bedside: A role for erythropoietin in sepsis" pps
Ngày tải lên :
13/08/2014, 20:22
... disappointing for many years, leading to a reappraisal of the mechanisms underlying sepsis in the search for novel therapies Apoptosis is pivotal in the relative immunosuppression that can lead ... norepinephrine in renal failure Kidney Int 1995, 48:806-813 65 Allegra A, Galasso A, Siracusano L, Aloisi C, Corica F, Lagana A, Frisina N, Buemi M: Administration of recombinant erythropoietin ... the administration of EPO attenuates tissue injury In a rat model of necrotising pancreatitis, EPO led to a reduction in all features of sepsis-induced acute lung injury, including circulating...
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Báo cáo y học: "A role for Numb in p53 stabilization" pps
Ngày tải lên :
14/08/2014, 08:21
... than initially thought The well characterized binding between the amino termini of the two proteins causes a conformational change, which allows binding between the DNA-binding domain of p53 and ... through interaction with the ubiquitin ligase Itch It is interesting to note that rather than inhibiting ubiquitination, Numb can enhance the degradation of Gli1 by Itch - again pointing to a rather ... the acidic domain of MDM2 [18,19] It is now thought that it may be this second stage of binding that is critical for ubiquitination of p53, and it is possible, therefore, that Numb inhibits this...
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Báo cáo Y học: Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts A role for phosphoinositide 3-kinase pot
Ngày tải lên :
24/03/2014, 03:21
... but instead acts as a cofactor for the cleavage and activation of PAR4 [27] Thrombin has been shown to cleave and activate PAR1, PAR3 and PAR4, whereas trypsin cleaves and activates PAR2 As duodenase ... (MEK1 inhibitor) and GF109203X (protein kinase C inhibitor) indicating that each of these pathways has a modulatory rather than a mandatory role to play in mediating the proliferative response In ... PAR3 and PAR4 [11] Interestingly, thrombin has now been demonstrated to cleave and activate PAR1, PAR3 and PAR4 whereas trypsin and tryptase activate PAR2 [12] Certain other proteases, including...
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Báo cáo y học: "A role for MCP-1/CCR2 in interstitial lung disease in children" pps
Ngày tải lên :
12/08/2014, 18:22
... bronchoalveolar lavage and participated in the study design TN performed bronchoalveolar lavage and patient characterization GZ and CP participated in the experimental analyses DR and DJS participated ... Yamamoto T, Hiraga Y, Ando M: Measurement of serum monocyte chemoattractant protein1 and its clinical application for estimating the activity of granuloma formation in sarcoidosis Sarcoidosis ... restrictive lung function parameters and ILD disease severity, indicating a relevance of the MCP-1/CCR2 axis in the pathogenesis of pediatric ILD Infiltrating T cells are a characteristic feature of...
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Báo cáo y học: " Mechanical ventilation in the ICU- is there a gap between the time available and time used for nurse-led weaning?" pot
Ngày tải lên :
13/08/2014, 23:20
... discrepancies between the time used for weaning and time available for weaning and 2) to analyse the patient and systemic factors were associated with the time available for weaning that is actually ... actually used for weaning The time used versus time available for weaning ratio represents a new way of reporting the weaning status and process at an organisational level Although various patient ... weaning in an intensive care unit in Norway Nurs Health Sci in press Katz MH: Multivariable Analysis: A Primer for Readers of Medical Research Ann Intern Med 2003, 138:644-650 Esteban A, Alia...
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Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx
Ngày tải lên :
20/02/2014, 11:20
... MSSAE added to growing SVT2 cells 125Ilabelled MSSAE was detached by high salt from SVT2 cells at increasing time intervals In the insert, autoradiographic scans of the SDS/PAGE runs D and M mark ... repeats Nature 366, 751756 Papageorgiou, A. , Shapiro, R & Acharya, K (1997) Molecular recognition of human angiogenin by placental ribonuclease inhibitor an X-ray crystallographic study at 20 A ... reconstituted in the presence of growing broblasts into the parent dimeric protein, which is internalized as a native-like dimeric RNase They also indicate for the rst time that when BS-RNase is internalized...
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Báo cáo khoa học: A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components ppt
Ngày tải lên :
07/03/2014, 11:20
... Vector Laboratories, Burlingame, CA) was used as secondary antibody (1 : 100 dilution in NaCl ⁄ Pi) Staining was performed with a standard protocol using the biotin–avidin-based Vectastain Elite ... b-hexosaminidase is in uenced by SG Although b-hexosaminidase activity was already detected at day 0, the intracellular content of this enzyme increased markedly after days of culture, and reached a plateau ... (IL)-3-containing medium were analyzed for total intracellular b-hexosaminidase activity Results are expressed as percentages, where the b-hexosaminidase content in SG+ ⁄ + cells at day 33 is set as...
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Báo cáo khoa học: A pre-docking role for microtubules in insulin-stimulated glucose transporter 4 translocation ppt
Ngày tải lên :
16/03/2014, 06:20
... Stockli J, van Dam EM, Winata S, Wasinger V, Simpson F, Graham M, Junutula JR, Guilhaus M et al (2005) Characterization of the role of the Rab GTPase-activating protein AS160 in insulinregulated GLUT4 ... analysis For normally distributed data, population averages are given as mean ± SEM and statistical significance was tested using Student’s t-test Statistical significance between exponential distributions ... serine kinase substrates Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain J Biol Chem 277, 22115–22118 Miinea CP, Sano H, Kane S, Sano E, Fukuda M,...
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LOOKING for a FIGHT IS THERE A Republican War on Science? potx
Ngày tải lên :
22/03/2014, 23:20
... Republican War on Science, journalist Chris Mooney made the case that, again and again, even overwhelming scientific consensus has met immovable political obstacles And, again and again, those obstacles ... (now-dissolved) Tobacco Institute of Australia The teaching of creationism is much less of a hot button issue in Australia than in America, partly because belief in Biblical literalism is much weaker ... less in pretending that DDT (a commodity chemical) is a panacea for malaria and as far as I can see none at all in “intelligent design” Intelligent design isn’t even a particularly congenial theory...
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is there a new vision for maghreb economic integration
Ngày tải lên :
22/05/2014, 12:51
... Recent analysis on Maghreb countries’ revealed comparative advantage and export specialization also reveals that Tunisia’s exports of beverages have a strong comparative advantage in the Maghreb market ... remains much lower than in other regional groupings Advances in intra-industry trade over the period were mainly due to increases in intra-industry trade in machinery and transportation goods in ... prospects for regional integration is whether there is potential for increased intraregional merchandise trade after accounting for other factors deterring trade, such as market size, geographical and...
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báo cáo hóa học: " A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells" pot
Ngày tải lên :
19/06/2014, 22:20
... Rintahaka J, Søby S, Horan KA, Poltajainen A, Østergaard L, Paludan SR, Matikainen S: Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVSdependent ... Cambridge, MA), STING (Abcam, Cambridge, MA) or a mouse monoclonal antibody against gG1 (Abnova, Taipei, Taiwan) for 24 hours at 4°C, blots were washed and incubated in the presence of an horseradish ... fold) isolated from the brains of infected animals (Figure 3B) in the absence of significant increases in levels of this viral sensor in total brain protein isolates (Figure 3A) Finally, we assessed...
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Báo cáo hóa học: " Supplement use in sport: is there a potentially dangerous incongruence between rationale and practice?" docx
Ngày tải lên :
20/06/2014, 00:20
... studies are not suitable for hypothesis testing Results from quantitative analyses, assuming adequate sampling and appropriate statistical analyses are objective and comparable Data from this type ... performance enhancement and/or health maintenance [10,15,34-37] including: caffeine, ephedrine, creatine, whey protein, antioxidants, ginseng, multivitamins, vitamin C, iron, Echinacea and magnesium ... athletes can be investigated by analyzing quantitative or qualitative data Although qualitative approaches have the advantage of producing deep understanding of athletes' motivations, data from these...
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A Role for the International Criminal Court in the Fight against Terrorism? potx
Ngày tải lên :
10/07/2014, 13:21
... proceedings and the proceedings before the International Criminal Tribunal for Former Yugoslavia indicate that prosecutions by international criminal tribunals are certainly not always barred by ... easily be dismissed as an inappropriate interference with the internal affairs of the affected state Arguments in support of including internal terrorism 14 The alternative to having perpetrators ... prosecution and trial as from the day after tomorrow 18 The ICC obviously has an important role to play in dealing with acts of internal terrorism targeting a state in political anarchy Inactivity...
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