is adjuvant radiotherapy necessary

... mother, who is his sister, does what she can to help However the amount of help she can give is limited for she is a housewife and my father is not too keen on giving unending assistance to someone ... (my uncle) who is so irresponsible So my uncle moans about his misfortune and complains that no one wants to help him What he will not admit is that he is the cause of his own misery He suffers ... hope is there for children brought up here? On the other hand one of my father’s cousins is careful about his children He only has three, all of which are given a good home to grow up in he is...

Ngày tải lên: 21/07/2014, 20:20

Ngày tải lên: 17/08/2015, 11:16

Ngày tải lên: 29/08/2016, 20:44

... lumen Visualisation of shape and location Wall structures not imaged Intermittent snapshots or repeat contrast injections necessary QCA measurements prone to magnification errors Visualisation ... stent thrombosis include smaller minimal stent area , stent under expansion, persistent edge dissections, incomplete stent apposition and incomplete lesion coverage ,geographic miss, tissue protrusion ... resulting in an ischemic FFR (predictive value of 40%) If the pre-intervention side branch MLA is > 2.4 mm2, provisional side branch PCI can usually be deferred  If the side branch MLA is

Ngày tải lên: 15/11/2016, 15:26

... resistance to apoptosis Apoptosis is a tightly regulated mechanism for the disposal of damaged cells and to remove cells during normal growth and development [27,40] Cells that undergo apoptosis ... N-terminal myristoylation sequence and unusual in light of their potential to promote signaling In this study, we demonstrated that JSP1 is myristoylated Although this modification is not required ... induced apoptosis This study illustrates that the toxicity of JSP1-wt presents a technical challenge that prohibits functional analysis using overexpression systems Consistent with this, we have...

Ngày tải lên: 16/02/2014, 14:20

... Cassian Bon for the gift of convulxin This work was supported by the British Heart Foundation S.P.W is a British Heart Foundation Senior Research Fellow J F is a Wellcome Trust Senior Research Fellow ... association with the FcR c-chain, although it is not clear how the cytoplasmic tail supports the association The molecular basis of this interaction is still being studied We have shown by transient ... thromboxane receptor antagonists [30] (B T Atkinson & S P Watson, unpublished) The most likely explanation for these observations is that a certain receptor density is required for functional...

Ngày tải lên: 22/02/2014, 07:20

... toxin is endocytosed via both clathrin-dependent and -independent mechanisms and is delivered to EEs [18–20] There is no known protein receptor for Stx B subunit (StxB), and the mechanism by ... (AlF4)) is an activator of small GTPases and is well-documented to block recycling of Tfn from the RE [5,49] Although the precise target of AlF4) at the RE is not known, the effect of this drug ... to this sequestration appears to have been to develop a mechanism to exploit retro- Shiga toxin in the Golgi grade transport out of the Golgi into the ER While this process is also slow, it is...

Ngày tải lên: 16/03/2014, 04:20

... of Ku-80 IR gene is consistent with previous report that the stability of Ku-70 is compromised by the absence of Ku-80 [57] This is the first report to show that Ku-80 expression is suppressed effectively ... 70-kDa proteins were visualized by silver staining (unpublished data) In contrast, only the 70 kDa subunit was observed by South-Western blot analysis (Fig 3A) This is consistent with previous ... RNAi assays (Fig 6A) Double-stranded RNAi is an effective method for disrupting expression of specific genes in higher organisms, especially Caenohabditis elegans [43–45] Recently, it was reported...

Ngày tải lên: 17/03/2014, 23:20

... the Inside This is a much greater risk than permitting access from the Outside to the isolated DMZ • DMZ (Demilitarized Zone)—The DMZ is an isolated network, or networks, which is usually accessible ... afterthought Why Network Security Is Necessary Today, the Internet is made up of tens of thousands of networks, interconnected without boundary Network security is essential in this environment because ... host is a host that is running only those services necessary CiscoSecurePIX.book Page Friday, November 16, 2001 10:35 AM Secure Network Design Defined to make it perform its application duties Unnecessary...

Ngày tải lên: 28/03/2014, 22:20

... language is that all English learners want to speak English well; however, most learners don't want to spend time on learning English on their own (Which is probably why they sign up for English classes ... time on learning English is that they associate learning English with unpleasant things When they think "learning English", they think about boring English classes, boring exercises and boring homework ... English exam However, he will not read a book in English for 30 minutes every day He just doesn't feel that learning English is pleasant enough, so he will only it if he has to The problem is...

Ngày tải lên: 04/04/2014, 03:21

... [006] - Programas demo PLC S7-1200 da SIEMENS (Simatic) This configuration example CE-X25 helps to solve the tasks displayed The focus is on the library blocks which enable SMS-Sending and SMS-Receiving ... Startup-Code and library with the actual version counter V1.2 and the append ant documentations is now adapted to STEP V11 Additional search terms wireless, m2m, without server Doc técnico blog...

Ngày tải lên: 01/07/2014, 21:04

... private tuition is that the students can become too dependent on the tutors and cannot function on their own Everything has to be spoon-fed Private tuition is only necessary if the child is really ... thinking that their tuition teachers will cover the lessons for them later What they not realize is that it is so much easier to pay attention in class than having to spend extra time in the afternoons ... difficult to follow, as long as I not neglect my work Mathematics, Science, Geography, History, and English are not that difficult to handle provided I take an interest in them and put in some...

Ngày tải lên: 21/07/2014, 20:20

... bliss and to believe in it would be a folly It is not gold that makes good people or good countries It is knowledge Knowledge is the only thing which can come to the help of mankind Education is ... Today war is not a mere matter of bravery of courage Wars are won or lost on the basis of literacy Modern weapons are so sophisticated that an illiterate soldier cannot use them Education is not ... knowledge and for peace and war education is necessary We can never be free if we depend on other countries for the technical know-how Even if practical knowledge is acquired in the fields and the factories,...

Ngày tải lên: 21/07/2014, 20:20

... results from the European Organisation for Research and Treatment of Cancer trial 10902 J Clin Oncol 2002, 19:4224-37 Mauri D, Pavlisdis N, Ioannidis JP: Neoadjuvant vs adjuvant systemic treatment ... Following NACT, traditionally ALND is performed as a part of optimum breast surgery This however is associated with considerable morbidity [11,12] A less aggressive approach is therefore sought for, making ... sentinel lymph node biopsy is feasible and reliable even in locally advanced carcinoma after NACT The possibility of skip metastasis is perhaps an exaggerated apprehension There is a high Table Single...

Ngày tải lên: 09/08/2014, 01:24

... comparison with the isotype control, #P 0.05 in comparison with W3/25, ĐP 0.05 in comparison with OX35, &P 0.05 in comparison with RIB5/2 Role of molecular features of the antibodies Isotype, ... association rate constant kass, the dissociation rate constant kdiss, and the affinity constant KA (kass/kdiss) were calculated Adjuvant arthritis and anti-CD4 treatment Lewis rats (812 weeks old) were ... JF, Wilson RE, Carlson RP, Lewis AJ: Lymphoid abnormalities in rats with adjuvant- induced arthritis I Mitogen responsiveness and lymphokine synthesis Ann Rheum Dis 1984, 43:847-855 28 Schmidt-Weber...

Ngày tải lên: 09/08/2014, 03:24

... other inflammatory sites, is one of the hallmarks of rheumatoid arthritis [29,30] One of the mechanisms that can contribute to this phenomenon is inhibition of apoptosis due to stimulation of ... pathological manifestations of adjuvant- induced arthritis (a) Effect of IB-MECA on the pathological features of joint destruction in adjuvant arthritis Shown are representative histology sections obtained ... from AIA rats in comparison with the corresponding naïve tissues (P < 0.01) Normal synovial tissue could not be evaluated for receptor expression since it is too thin to be excised In IB-MECA-treated...

Ngày tải lên: 09/08/2014, 07:20

... diminished p21 expression in vivo is the mechanism that underlies increased radiosensitivity at higher doses; however it is clearly associated statistically To us it is an attractive hypothesis ... inactivation in each group is statistically distinct at circa Gy However the distribution of tumor cell radiosensitivity with genotype is better seen when radiosensitivity of tumor cells is expressed as ... tumor types or between pairs of radiotherapy protocols [1,18] and while this method has significant statistical power in such a pair-wise comparison, Page of 14 it is limited in comparing response...

Ngày tải lên: 09/08/2014, 09:20

... underwent adjuvant chemotherapy with FOLFOX or FOLFIRI regimen were not recommended for concurrent radiotherapy due to increased toxicity and this result is shown in Table Statistical analysis The ... followed and decisions for adjuvant pelvic RT were made at physicians’ discretion In Table 2, although not statistically significant, group S+R shows higher rates of lymph node metastasis (Duke C), ... respectively Discussion Metastatic spread of colorectal cancer occurs mainly via the portal system and the incidence of isolated liver metastasis in rectal cancer is seven times higher than isolated...

Ngày tải lên: 09/08/2014, 09:20

... included in the current immunohistochemical study Statistical analysis of the CA12 expression, histologic grade, and radiotherapy outcomes The primary endpoints for radiotherapy outcome were DFS ... start of radiotherapy to local relapse and relapse in any site, respectively Local recurrence included the recurrent diseases at the cervix and parametrial tissues Persistent local diseases at ... of the pelvis ± positron emission tomography except for the 36 patients who also undertook laparoscopic lymph node staging as a part of our previous clinical trial Radiotherapy consisted of whole-pelvic...

Ngày tải lên: 09/08/2014, 09:20

... treated with this new technology in this centre This study is an audit of the RA experience to ensure that the newer therapy is recommended with proper evidence Methods The audit is of the first ... beam radiotherapy is delivered by a certain number of machine monitor units (MUs), a measure of machine radiation output MUs are important as second cancer risk in patients treated with radiotherapy ... radiation therapists were on the lowest paid level qualified to perform the relevant duties In our NSW system, this meant that the two therapists involved in the treatment, Table Costs of radiotherapy...

Ngày tải lên: 09/08/2014, 09:21