is a new aetiological factor in the knee osteoarthritis

... technological advances to produce higher quantities of paper at a faster rate An example of this is described by author Nancy Ohanian in Spain: "about 1150, papermakers in Xatina, Spain, began to use water ... its approach to manage its weaknesses A SWOT analysis starts with the definition of the industry Industry: This SWOT analysis is used to analyze the factors that will assist Booshoot Gardens in ... fiber in a process called pulping The smaller the individual fibers strands, the finer pulp, the finer the paper The pulp is then placed on a screen and the water is dried out As the water drains...

Ngày tải lên: 18/03/2014, 02:20

... because no data have been available regarding clinicopathological factors in BE and EAC so far Our findings of an increased MMP-1 expression in EAC is well in line with results obtained in other ... Takeo S, Harada T, Okazawa T, Yanai H, Okita K: Matrix metalloproteinase-7 and matrix metalloproteinase-9 are associated with unfavourable prognosis in superficial oesophageal cancer Br J Cancer ... be promising for further investigations in the carcinogenesis of Barrett-associated adenocarcinomas due to a cancer stem cell hypothesis 10 Acknowledgements The authors thank the assistance of...

Ngày tải lên: 18/06/2014, 16:20

... 92:271-277 Athanassiadou P, Grapsa D, Athanassiades P, Gonidi M, Athanassiadou A- M, Tsipis A, Patsouris E: The prognostic significance of COX-2 and survivin expression in ovarian cancer Pathol Res Pract ... K, Kuragaki C, Ueda Y, Aki T, Ikegami H, Yamazaki M, Ito K, Nagamatsu M, Nishizaki T, Asada M, Kameda T, Wakimoto A, Mizutani T, Yamada T, Murata Y: Prognostic significance of p53 mutation in suboptimally ... Menicagli M, Cosio S, Naccarato AG, Genazzani AR, Bevilacqua G, Cavazzana AO: P53 gene status in patients with advanced serous epithelial ovarian cancer in relation to response to paclitaxel-plus...

Ngày tải lên: 20/06/2014, 08:20

... TypA, LepA and EF-G share an additional three domains (Domains II, III and V) [39,40] EF-G contains a unique domain IV whereas LepA and TypA each have a unique C-terminal domain (CTD) The overall ... S2), the domains of each factor are highly conserved between the two species In addition, the four factors have many domains in common A GTP binding domain (Domain I) is present in all factors, while ... contains a unique domain, which might mediate factor specific interactions with the ribosome and facilitate different roles in translation In the case of SVR3/AtcpTypA, the C-terminal domain may...

Ngày tải lên: 11/08/2014, 11:21

... Page of Denmark) All the parameters were measured by computer-assisted morphometric analysis (Image Proplus version 5) and a mm square area was evaluated Statistical analysis Mean and standard ... analysis and interpretation, and drafting the manuscript PS participated in the design of the study and performed the statistical analysis FO performed the statistical analysis and helped to draft the ... data, TNF -a may lead to an increased activity of other proinflammatory pathways [56-58] The fact that IL-22 and IL17 not react in the same way in the SF of PsA would seem to indicate that they...

Ngày tải lên: 12/08/2014, 14:22

... smaller number of uncorrelated variables, called principal components, while maintaining the variability in the original variables More specifically, a principal component is a linear combination ... of the original standardized (µ = 0,σ = 1) variables (in this case, the four ASVAB components listed above) that maximizes the variance of that combination and has a zero covariance with all ... RCS The apparent rise in the demand for college among young Americans is most sensibly attributable to a perception that the financial returns to attaining a college degree have risen The popular...

Ngày tải lên: 23/03/2014, 02:20

... maintain its DNA-binding domain in an active conformation RLjunRP is an  40 kDa protein that forms an 80-kDa protein–DNA adduct To assess approximate molecular mass of the factors interacting ... Phosphatase-treated nuclear extracts were assayed for their DNA-binding capacity in standard EMSA UV crosslinking of DNA–protein adduct The EMSA reaction was carried out using ng labelled Jun)25 and ... stated otherwise Healthy female inbred rats of Wistar strain weighing 150–170 g were procured from the Animal Facility, Jawaharlal Nehru University, New Delhi, India Animals were fed water and...

Ngày tải lên: 23/03/2014, 20:22

... domain B) from AMY2 (in green) and TAA (in black) The superimpositioning was guided by the catalytic acids (D179AMY2, E204AMY2, and D289AMY2 and D206TAA, E230TAA, and D297TAA) The invariant Y51AMY2 ... conserved in plant a- amylases, has a role in substrate binding and activity This local region was different in structures of nonplant a- amylases having a longer ba loop which typically contained aromatic ... the Met52AMY2 (Met53AMY1) and Trp83TAA (Fig 1A) Also the larger TAA loop in TAA appeared to hinder binding of the substrate beyond subsite )3/)4 as illustrated by global views of AMY2 and TAA...

Ngày tải lên: 31/03/2014, 08:20

... Rintahaka J, Søby S, Horan KA, Poltajainen A, Østergaard L, Paludan SR, Matikainen S: Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVSdependent ... fold) isolated from the brains of infected animals (Figure 3B) in the absence of significant increases in levels of this viral sensor in total brain protein isolates (Figure 3A) Finally, we assessed ... RIP3 and STING (Panel D) by immunoblot analysis For comparison purposes, DAI expression in the murine neuron-like cell line CATH .a (Panel A: Cath) and murine small intestine tissue (Panels A and...

Ngày tải lên: 19/06/2014, 22:20

... independently associated with the diagnosis of symptomatic knee osteoarthritis As the knee osteoarthritis risk is strongly elevated in occupations that involve both kneeling/squatting and heavy lifting/carrying, ... (handball, volleyball, basketball); apparatus gymnastics, shot put, javelin, hammer throwing, wrestling; and body building, strength training The mean age at initial radiographic diagnosis of knee ... finally qualify as cases, patients had to have at least grade osteoarthritis according to the reference radiologist's assessment 21.7% of the cases had a grade knee osteoarthritis (n = 64; mean...

Ngày tải lên: 20/06/2014, 00:20

... the manuscript MU was involved in the overall supervision, preparation of the questionnaire and collection and analysis of data TA was involved in the study design, analysis and was involved in ... critically reviewing the manuscript FA and MUC participated in the designed the Page of study and participated in the preparation of the protocol and data collection MU participated in overall ... Cardiac, Vasovagal (Risk Factors: Younger Age, Lower weight, 1St time donation) [34] • 12 times increase in Anginal and Vasovagal complications (Risk Factor: 1st time donation) [35] • Overall increase...

Ngày tải lên: 20/06/2014, 04:20

... the manuscript MU was involved in the overall supervision, preparation of the questionnaire and collection and analysis of data TA was involved in the study design, analysis and was involved in ... critically reviewing the manuscript FA and MUC participated in the designed the Page of study and participated in the preparation of the protocol and data collection MU participated in overall ... Cardiac, Vasovagal (Risk Factors: Younger Age, Lower weight, 1St time donation) [34] • 12 times increase in Anginal and Vasovagal complications (Risk Factor: 1st time donation) [35] • Overall increase...

Ngày tải lên: 20/06/2014, 07:20

... variation is not necessarily linear, but the results obtained in this case can be generalized This type of variation has also the advantage of being the simplest model which is able to integrate ... satisfactorily the estimation of N PARTICULAR CASE OF A LINEAR PIECEWISE VARIATION OF THE AUTOCORRELATION MATRIX EIGENVALUES The theoretical validity of this criterion will be demonstrated in ... idea behind the new method is that estimating N is equivalent to finding how many eigenvalues are associated to each of the two subspaces, signal and noise This can be considered a classification...

Ngày tải lên: 23/06/2014, 01:20

... of the rest of the paper is as follows In Section we prove the main result This proof consist of stating six discharging rules, and verifying that after the discharging phase, each vertex has ... delete the sets that contain and 4, and we add the sets {1, 2}, {3}, and {4, 5} As above, we assume that 10 is uncovered (since the other case is easier) Since 10 is uncovered, P contains the set ... v is a 1-cluster, then note / that each neighbor w of v has at least one other neighbor in D (otherwise v and w are indistinguishable) So v gives each neighbor charge at most 1/5 Thus, v retains...

Ngày tải lên: 08/08/2014, 01:20

... rs3738919 in a first sample of French Caucasian families, the same trend in replication sample 2, and again a significant association in replication sample (European Caucasian families) Finally, ... association and linkage for the rs3738919-C allele of the ITGAV gene with RA in the European Caucasian population, suggesting ITGAV as a new minor RA susceptibility gene in this population Page ... disease Sample Sample (Table 1) contained the DNA from 265 European Caucasian unrelated trio families with the same characteristics as sample 1, except for a shorter mean disease duration and a different...

Ngày tải lên: 09/08/2014, 10:20

... Kizawa H, Kou I, Iida A, Sudo A, Miyamoto Y, Fukuda A, Mabuchi A, Kotani A, Kawakami A, Yamamoto S, Uchida A, Nakamura K, Notoya K, Nakamura Y, Ikegawa S: An aspartic acid repeat polymorphism in ... Mustafa Z, Dowling B, Chapman K, Sinsheimer JS, Carr A, Loughlin J: Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population Arthritis ... Arthritis Research & Therapy Vol 11 No Gruber et al Spanish Caucasians [8] and work by Mustafa et al in British Caucasians [9] Our laboratory has become interested in asporin in the human intervertebral...

Ngày tải lên: 09/08/2014, 14:20

... performed at baseline and at weeks 1, and after start of treatment Sociodemographics and clinical data were collected at baseline, and the investigators administered the MADRS, the Clinical Global Impression ... of the factor analysis confirmed the unidimensionality of the MADRS-S: each item contributed to the first factor axis with a factor loading of at least 0.50, explaining 45% of the total variance ... conceived and participated in the design of the current analysis BF oversaw execution of statistical analyses and was responsible for their coordination Both authors read and approved the final manuscript...

Ngày tải lên: 11/08/2014, 17:20

... variables measured at day 1, day 6, and the change in value between day and Stata 9.0 (StataCorp, College Station, Texas) computer software was used for statistical analysis All interval data ... data in tables and text are presented as mean with standard deviation in parentheses Data presented in graphs are mean with error bars indicating the standard error of the mean (SEM) The odds ratios ... ratios for the change between day and day of mechanical ventilation were calculated for each variable (Table 3) The only variable associated with death in these analyses was a decrease in the Crs...

Ngày tải lên: 12/08/2014, 13:22

... chi-square (MHC) tests were used to test for trend in the categorical analysis The data were managed and analyzed using SAS version 9.1 (SAS Inc., Cary, NC, USA) Statistical power of single associations ... Luciferase Assay System and luminometer (VICTOR3, Perkinelmer, Waltham, MA, USA) And the relative luciferase activity was normalized to the protein concentration and b-galactosidase activity Statistics ... this limit were assumed to be pg/mL for the statistical analysis The inter- and intraassay coefficients of variance were below 10% Protein concentration of BAL samples was measured for standardization...

Ngày tải lên: 12/08/2014, 13:22

... Jr, Amado VM, Caserta R, Dalla Valle Martino M, Pasternak J, et al.: Ventilator associated pneumonia: comparison between quantitative and qualitative cultures of tracheal aspirates Crit Care ... of VAP was considered as any decrease of X-ray findings accompanied by an increase of the pO2/FiO2 ratio Antimicrobial therapy of VAP was selected by attending physicians according to published ... requiring the administration of vasopressors [12] Sedation was achieved in all patients with the intravenous administration of midazolame and propofol 1% Upon enrolment in the study, quantitative...

Ngày tải lên: 12/08/2014, 23:23