iron oxidative stress and health

... OXIDATIVE STRESS AND DISEASES Edited by Volodymyr Lushchak and Dmytro V Gospodaryov Oxidative Stress and Diseases Edited by Volodymyr Lushchak and Dmytro V Gospodaryov ... 4 Oxidative Stress and Diseases Evidences for connection of oxidative stress with the stresses induced by other factors are promptly gained The potency of transition metals, some herbicides and ... response to oxidative stress: Bacteria, fungi, plants and animals Comparative Biochemistry and Physiology C Vol 153, pp.175-190 Lushchak, V.I (2011b) Environmentally induced oxidative stress in...

Ngày tải lên: 12/02/2014, 16:20

... oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues Particle and Fibre Toxicology 2011 8:20 Submit your next manuscript to BioMed Central and ... lesions on a standard chow diet It is used for studies of hyperlipidemia and atherosclerosis, and has been used extensively in understanding the mechanisms of lipoprotein metabolism and atherosclerosis ... insights into the roles and mechanisms of PM2.5-associated physiology and pathology In summary, our data demonstrate the important effects of PM2.5 exposure on oxidative stress and mitochondrial alterations...

Ngày tải lên: 06/03/2014, 19:20

... cardiac oxidative stress, myocyte apoptosis and the DCM phenotype Materials and methods * Animals WT CYP2E1 cTnTR141W Fig Determination of the levels of cytochrome c release, cleaved caspases and ... Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression Mutagenesis 22, 189–194 McKillop IH & Schrum LW (2005) Alcohol and liver cancer Alcohol ... Pacher P (2005) Role of oxidative- nitrosative stress and downstream pathways in various forms of cardiomyopathy and heart failure Curr Vasc Pharmacol 3, 221–229 33 Narula J, Pandey P, Arbustini E,...

Ngày tải lên: 22/03/2014, 16:20

... exposed to oxidative stress (2.5 mm and mm HA) with PARP inhibition and allowed to develop, the spores showed faster germination (32 h and 60 h) as compared to cells exposed to oxidative stress alone ... oxidative stress (Fig 4A,B) Under oxidative stress, partial inhibition of PARP activity led to altered growth, suggesting that oxidative stress could be leading to cell cycle arrest [22] and that ... 20 Oxidative stress induces PARP activation PARP activity in D discoideum was assayed at various time points (5, 10, 20 and 60 and h) after HA stress PARP activity was increased initially, and...

Ngày tải lên: 23/03/2014, 07:20

... protein in Scrambleand ANT1 and ANT2 siRNA-transfected cells; the 33 kDa band corresponds to ANT proteins, the 43 kDa band corresponds to actin (E) Western blot analysis of FLAGANT1 and FLAG-ANT2 ... effects of BA, ATR and ANT1 siRNA on cell viability and glucose consumption (A,B) Cell growth curves analyzed by crystal violet assay in BA and vehicle-treated (A) and in ATR and vehicle-treated ... survival, thus indicating that ANT1 effect is mediated by oxidative stress A possible explanation for the ANT1-silencing effect on oxidative stress and cell survival could reside in the loss of the basal...

Ngày tải lên: 29/03/2014, 09:20

... hyperthermal stress on antioxidant induction and on apoptotic markers (caspase-like activation and ⁄ or DNA degradation) in order to demonstrate the concomitant involvement of oxidative stress and apoptosis ... 6B) Effect of heat stress on antioxidant defenses and bleaching in animal tissue of A viridis The occurrence of oxidative stress in the animal tissue (ectoderm and gastroderm) and freshly isolated ... studies and supports the occurrence of an oxidative stress period in heat stressed A viridis [24] We suggest that apoptosis induction could be the consequence of the previous oxidative stress...

Ngày tải lên: 30/03/2014, 10:20

... another anti -oxidative biomarker, was remarkably lower in group than in groups and 3, and significantly lower in group than in group at 24 h and 72 h after IR injury On the other hand, this protein ... apoptosis, and suppressing oxidative stress in this experimental setting of acute kidney IR injury The cause of discrepancy between mRNA and protein expressions of HO-1 on both day and day after ... experiments, and drafted the manuscript LTC, THT, YLC, SC, PLS, and CHY were responsible for the laboratory assay and troubleshooting KCC, SL, and HKY participated in refinement of experiment protocol and...

Ngày tải lên: 18/06/2014, 19:20

... Selfperceived occupational stress and distress in a Scottish police force Work Stress 1997, 11:118-133 Kirkcaldy B, Shephard RJ: Occupational stress, work satisfaction and health among the helping ... good health and The aims of the study were: To explore physical and mental health in the Norwegian police service To explore the relationship between the frequency and severity of perceived job stress ... negative impact of stress in police work is manifested in different ways, such as somatic and mental health problems and burnout [3,4,7,8], and it depends on the frequency, the intensity and how the...

Ngày tải lên: 20/06/2014, 00:20

... variation in oxidative stress markers in healthy and type II diabetic men Chronobiol Int 2002, 19:423-439 68 Hardeland R, Coto-Montes A, Poeggeler B: Circadian rhythms, oxidative stress and antioxidative ... against oxidative stress [7] was verified by testing the correlation between levels of 8OHdG, reflecting oxidative stress, and the reducing capacity (corresponding to a defense against oxidative stress) ... Environ Health Perspect 2004, 112:666-671 Lai CH, Liou SH, Lin HC, Shih TS, Tsai PJ, Chen JS, Yang T, Jaakkola JK, Strickland PT: Exposure to traffic exhausts and oxidative DNA damage Occup Environ...

Ngày tải lên: 20/06/2014, 00:20

... of erythrocytes to handle the hydrogen peroxide to molecular oxygen and water [11,29] GSH-Pxs catalyze the peroxides and reduce the glutathione to form oxidized glutathione and water [30] A significant ... Press, New York, 1983 Andreyev AY, Kushnareva YE, Starkov AA Mitochondrial metabolism of reactive oxygen species Biochemistry (Mosc) 2005, 70, 200-214 Athar M Oxidative stress and experimental carcinogenesis ... Adam-Vizi V Effect of cypermethrin on oxidative stress after dermal application 259 10 11 12 13 14 15 16 17 18 19 20 21 22 Exacerbated responses to oxidative stress by an Na+ load in isolated nerve...

Ngày tải lên: 07/08/2014, 23:22

... the context of the culture and value system in which they live and in relation to their goals, standards, and concerns" [5] In general, HRQL can be influenced directly and indirectly by various ... of psychological stress and health related quality of life among patients with various cardiovascular conditions To further investigate the relationship of psychological stress and quality of life ... Nasser, and Khan Younis hospital) and the geographically and administratively related primary health care clinics were pinpointed for the selection of the study population Each selected primary health...

Ngày tải lên: 08/08/2014, 21:20

... 0.01, and §p < 0.001 compared with control group L = Live; A = Apoptosis; N = Necrosis References Kode A, Yang SR, Rahman I: Differential effects of cigarette smoke on oxidative stress and proinflammatory ... ethidium bromide and appeared red Percentage of viable (white bars), apoptotic (grey bars) and necrotic/late apoptotic (black bars) determined by counting as described in Materials and Methods Results ... cells underwent morphological changes in response to CSE and lost their characteristic spindle-shaped morphology as is evident from figs c and d SAEC were shown to be more sensitive to CSE compared...

Ngày tải lên: 12/08/2014, 15:21

... vitro and lung in vivo under oxidative stress Am J Physiol 1995, 269:L285-L292 Moodie FM, Marwick JA, Anderson CS, Szulakowski P, Biswas SK, Bauter MR, Kilty I, Rahman I: Oxidative stress and cigarette ... smoke extract (CSE 0.5 and 1.0%) dose-dependently increased the levels of nuclear NF-κB RelA/p65 in SAEC after hr treatment (Figures 11A and 11B) Discussion Oxidative stress and inflammatory events, ... I: Oxidative stress in asthma and COPD: Antioxidants as a therapeutic strategy Pharmacol Ther 2006, 111:476-494 Rahman I, Biswas SK, Kode A: Oxidant and antioxidant balance in the airways and...

Ngày tải lên: 12/08/2014, 16:20

... between oxidative stress, inflammation and angiogenesis, where increase in tpO2 and reduce oxidative stress observed in responders is associated with lower microscopic scores of T-cells (CD4 and ... treatment and we found significant positive association between synovial 4-HNE expression and clinical measures of arthritis Several cellular and environmental sources of synovial oxidative stress ... oxidative stress and clinical parameters of disease activity and suggest that microscopically assessed levels of 4-HNE may closely reflect clinical scores of IA Synovial levels of oxidative stress, ...

Ngày tải lên: 12/08/2014, 17:22

... two isoforms of α-subunit (α1 and α2 by prkaa1 and prkaa2), two of β-subunit (β1 and β2 by prkab1 and prkab2), and three of γ-subunit (γ1, γ2 and γ3 by prkag1, prkag2 and prkag3) (Chen et al., 2009; ... be removed and recycled and the targeted proteins are degraded into small peptides (Glickman and Ciechanover, 2002; Hershko and Ciechanover, 1998; Komander and Rape, 2012; Naujokat and Sarić, ... targets (Mihaylova and Shaw, 2011)   13 1.1.5 AMPK and cancer As a central metabolic regulator allowing cells to cope with environmental stresses, especially typical tumor microenvironment like nutrient...

Ngày tải lên: 22/10/2015, 21:19

... TBARS and decreased concentration of TAS supports the oxidative stress in anoxia and reperfusion and suggests a possible role for anti oxidants in preventing neuro- 153 degeneration in anoxia and ... once and after removal of animals from desiccator, they were allowed to stay at normal conditions and were given normal diet for days and decapitated and the different brain regions (CC, CB and ... direct and secondary excitotoxic neuronal injuries in vivo Excitotoxicity, oxidative stress and apoptosis comprise major routs of hypoxic-ischemic neuronal death Each route is likely activated and...

Ngày tải lên: 26/10/2012, 09:07

... physically examined and interviewed by physicians and research nurses Information concerning education and socio-economic group was obtained by questionnaire, which was sent out beforehand Data on smoking ... regarding work, own health, family or conflicts at home or at work during the last five years Asthma, and colds, respectively, was defined as self-reported asthma and colds in 1968-1969 Health status ... linear regression model including VC, FEV1 and PEF and individual heights The other “standard” confounding factors for lung function measurements, gender and age, were not controlled for as the...

Ngày tải lên: 31/10/2012, 15:34

... and Volodymyr I Lushchak Chapter Oxidative and Nitrosative Stresses: Their Role in Health and Disease in Man and Birds 47 Hillar Klandorf and Knox Van Dyke Chapter Nitric Oxide Synthase and Oxidative ... Oxidative Stress: Regulation of Nitric Oxide Synthase 61 Ehab M M Ali, Soha M Hamdy and Tarek M Mohamed Chapter Iron, Oxidative Stress and Health 73 Shobha Udipi, Padmini Ghugre and Chanda Gokhale ... glycoxidation and carbonyl /oxidative stress 30 Oxidative Stress Molecular Mechanisms and Biological Effects The existence of a strong relation between carbonyl and oxidative stresses can be...

Ngày tải lên: 12/02/2014, 16:20

... general and not only to oxidative stress [5,6,31,32] Recently, it was demonstrated that the lipophilic iron chelator sih (salicylaldehyde isonicotinoyl hydra- Oxidative stress and intralysosomal iron ... against oxidative stress- induced mitochondrial and cellular damage when present in low concentrations during the oxidative stress period [15,33] sih was rst synthesized in 1953 [34] and its iron ... following oxidative stress Cells were seeded (500 000 well) and 24 h later exposed to oxidative stress, with or without sih-protection as described before Directly after end of the oxidative stress...

Ngày tải lên: 19/02/2014, 06:20