injury acute lung injury and acute respiratory distress syndrome

... tomography of two different models of acute lung injury/ acute respiratory distress syndrome (ARDS) (a) Computed tomography (CT) scan of pigs after saline lung lavage before and after recruitment maneuvers ... with acute respiratory distress syndrome; a randomized controlled trial JAMA 1999, 281:77–78 Gattinoni L, Caironi P, Pelosi P, Goodman LR: What has computed tomography taught us about the acute respiratory ... [1] (b) CT scan of acute respiratory distress syndrome patients before and after a recruitment maneuver with 60 cmH2O maximal inspiratory pressure maintaining PEEP values of 20 and 25 cmH2O without...

Ngày tải lên: 12/08/2014, 22:22

... The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome ... setting in acute lung injury acute respiratory distress syndrome patients Crit Care Med 2003, 31:300s-304s Gattinoni L, Carlesso E, Cadringher P, Valenza F, Vagginelli F, Chiumello D: Physical and biological ... Impairment of lung and chest wall mechanics in patients with acute respiratory distress syndrome Am J Respir Crit Care Med 1997, 156:1082-1091 Sugrue M, Hilman KM: Intra-abdominal hypertension and intensive...

Ngày tải lên: 12/08/2014, 20:20

... oxygen; ALI, acute lung injury; ARDS, acute respiratory distress syndrome; S, survived; D, died Overall results are means ± SD venous blood values), the physiological dead space, and the alveolar ... improve lung mechanics and gas exchange on a theoretical basis • This hypothesis was tested by studying respiratory mechanics (partitioned into lung and chest wall components), gas exchange and hemodynamics ... design and coordination and performed the measurements LL participated in the study design and coordination and performed the measurements GLB participated in the study design and coordination and...

Ngày tải lên: 12/08/2014, 23:23

... reference, sedation and muscle paralysis and PEEP levels are needed Abbreviations ACS: abdominal compartment syndrome; ALI: acute lung injury; ARDS: acute respiratory distress syndrome; FiO2: fraction ... in acute lung injury/ acute respiratory distress syndrome patients: a pilot study Critical Care 2010 14:R137 Authors’ contributions DV and J-MC conducted the research, collected, analysed and ... BJ and P-FP made substantial contributions to the conception and design of the study and approved the final version of the manuscript MM and SJ designed and supervised the research, analysed and...

Ngày tải lên: 13/08/2014, 21:21

... respiratory distress syndrome (ARDS) [1] Endotracheal suctioning (ETS), which is a common procedure in patients with acute lung injury (ALI) and ARDS, abolishes the positive airway pressure and even may ... data for the patients, and their underlying conditions and initial respiratory parameters are presented in Table Seven patients had ARDS and one had ALI at inclusion [17] Lung injury score (median ... End-expiratory lung volume EELV was 1550 ± 480 ml on 8–15 cmH2O PEEP (Table 1) at inclusion, and increased after lung volume standardization (see above) to 1677 ± 618 ml and 1719 ± 571 ml for ETS+LR and...

Ngày tải lên: 12/08/2014, 19:21

... exchange Five thousand units of heparin were given after the instrumentation was completely set up and the extracorporeal flow was started without oxygen flow at that time Acute lung injury was then ... the study and revised the manuscript JS participated in design and coordination IF performed the analysis and interpretation of the data and revised the manuscript NW conceived the study and participated ... A, Kaiser M, Pfeifer M, Gruene S, Schoelmerich J: Pumpless extracorporeal lung assist and adult respiratory distress syndrome Lancet 2000, 356(9225):219-220 10 Sussmane JB, Totapally BR, Hultquist...

Ngày tải lên: 13/08/2014, 15:21

... acute lung injury and acute respiratory distress syndrome: a randomized controlled trial JAMA 2008, 299:646-655 Eisner MD, Thompson BT, Schoenfeld D, Anzueto A, Matthay MA: Airway pressures and ... ventilator-induced lung injury (VILI) [1] To prevent alveolar cycling and derecruitment in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), high levels of positive end-expiratory pressure ... patients with acute lung injury and acute respiratory distress syndrome Am J Respir Crit Care Med 2002, 165:978-982 Luecke T, Pelosi P: Clinical review: Positive end-expiratory pressure and cardiac...

Ngày tải lên: 13/08/2014, 16:20

... The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome ... Griffith LE, et al.: A study of the physiologic responses to a lung recruitment maneuver in acute lung injury and acute respiratory distress syndrome Respir Care 2008 53:1441–1449 34 Constantin JM, ... recruitment maneuver, namely: 1) The nature and extent of lung injury, and 2) patient positioning Nature and extent of lung injury The nature of the underlying injury can affect the response to a recruitment...

Ngày tải lên: 13/08/2014, 20:21

... of the acute respiratory syndrome N Eng J Med 2003, 348:683-693 Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD: Incidence and outcomes of acute lung injury ... traumatic brain injury Neurocrit Care 2006, 5:108-114 Holland MC, Mackersie RC, Morabito D, Campbell AR, Kivett VA, Patel R, Erickson VR, Pittet JF: The development of acute lung injury is associated ... Piacentini E, Real J, Fernandez-Segoviano P, Romero PV, Hotchkiss JR, Blanch L: Massive brain injury enhances lung damage in an isolated lung model of ventilator-induced injury Crit Care Med 2005,...

Ngày tải lên: 13/08/2014, 23:20

... [8] and CT guided percutaneous approaches have a poor yield due to the patchy distribution of BOOP and small sample size The differential diagnosis includes Acute Interstitial Pneumonitis and respiratory ... returned and repeat chest radiograph showed right middle and lower lobe consolidation associated with recurrent hydro-pneumothorax A new intercostal drain was inserted and he was intubated and ventilated ... culture-negative respiratory failure in previously healthy patients The 'Air Leak Syndrome' type of BOOP is associated with persisting broncho-pleural fistula, pneumo-mediastinum and pneumopericardium and...

Ngày tải lên: 11/08/2014, 23:21

... abnormalities and therapeutic options Intensive Care Med 2001, 27:1699-1717 Haitsma JJ, Papadakos PJ, Lachmann B: Surfactant therapy for acute lung injury/ acute respiratory distress syndrome Curr ... infants with neonatal respiratory distress syndrome due to prematurity, lung malformations and infections [18,32-36] However there are aspects of the present work, both conceptual and technical, that ... tracer to lung structures not pertaining to the surfactant system (i.e infiltrating inflammatory cells), or to a combination of these ARDS = acute respiratory distress syndrome k21 and k12 =...

Ngày tải lên: 12/08/2014, 15:20

... volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome The Acute Respiratory Distress Syndrome Network N Engl J Med 2000, 342:1301-1308 ... thirty-day mortality in the Acute Respiratory Distress Syndrome (ARDS) in an adult ICU Anaesth Intensive Care 2004, 32:317-329 Ware LB, Matthay MA: The acute respiratory distress syndrome N Engl J Med ... composition and duration of surfactant administration List of abbreviations APACHE II scores on the acute physiology and chronic health evaluation ARDS acute respiratory distress syndrome BALF...

Ngày tải lên: 12/08/2014, 15:21

... and mechanisms of remodeling of the pulmonary circulation in acute and subacute lung injury In The Pulmonary Circulation and Acute Lung Injury Edited by Said SI Mount Kisko, NY: Futura Publishing ... in patients with acute respiratory distress syndrome Anesth Analg 1996, 82:574-581 Lundin S, Westfelt UN, Stenqvist O: Response to nitric oxide inhalation in early acute lung injury Intensive ... = deceased; BPN = bronchopneumonia; LISS = lung injury severity score; SAPS = simplified acute physiologic score; ARDS = acute respiratory distress syndrome; COPD = chronic obstructive pulmonary...

Ngày tải lên: 12/08/2014, 18:20

... a human lung adenocarcinoma cell line, NCI-H441, and human fetal lung explants H441 cells resemble bronchiolar epithelial Clara cells in phenotype and produce both SP-A and SP-B mRNA and protein ... saline; PI 3-kinase = phosphatidylinositol 3-kinase; RDS = respiratory distress syndrome; SD = standard deviation of the mean; SE = standard error of the mean; SP = surfactant protein; TPA = 12-O-tetradecanoylphorbol13-acetate ... Health NIH-HL-50050 and DK-25295 References Snyder JM, George TN, Miakotina OL: Insulin and lung development In Contemporary Endocrinology: Endocrinology of the lung: Development and surfactant synthesis...

Ngày tải lên: 12/08/2014, 18:20

... risk for ARDS and their value as predictive factors Abbreviations ALI = acute lung injury; ARDS = acute respiratory distress syndrome; BALF = bronchoalveolar lavage fluid; ICAM-1= intercellular ... lavage fluid (BALF) and serum levels (pg/ml) of the measured cytokines and adhesion molecules in at risk patients who developed or did not develop acute respiratory distress syndrome (groups B ... and VCAM-1 expression is induced mainly by IL1b and TNF-α However, the levels of TNF-α and IL-1 were not predictive for the development of the syndrome BALF soluble adhesion molecules sICAM and...

Ngày tải lên: 12/08/2014, 18:20

... pulmonary acid injury in a pig model Am J Respir Crit Care Med 1996, 154:1351–1356 Murray JF, Matthay MA, Luce JM, Flick MR: An expanded definition of the acute respiratory distress syndrome Am ... in ARDS Am J Respir Crit Care Med 1996, 154:1375–1381 Hansen-Flaschen JH: Acute respiratory distress syndrome Principles and Practice of Medical Intensive Care Edited by Carlson RW, Geheb MA Philadelphia: ... dose–response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with acute respiratory distress syndrome Eur J Clin Invest 1993, 23:499–502 26 Imanaka H, Hess...

Ngày tải lên: 12/08/2014, 18:21

... volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome The Acute Respiratory Distress Syndrome Network N Engl J Med 2000, 342:1301-1308 ... Thorsteinsson A, Frostell CG, Bonde J: Incidence and mortality after acute respiratory failure and acute respiratory distress syndrome in Sweden, Denmark, and Iceland The ARF Study Group Am J Respir Crit ... with acute lung injury and the acute respiratory distress syndrome Am J Respir Crit Care Med 2001, 163:1376-1383 Matthay MA, Folkesson HG, Verkman AS: Salt and water transport across alveolar and...

Ngày tải lên: 12/08/2014, 20:20

... 64 460 December 2004 Vol No Reutershan and Ley volumes for acute lung injury and the acute respiratory distress syndrome The Acute Respiratory Distress Syndrome Network N Engl J Med 2000, 342:1301-1308 ... phase References Ware LB, Matthay MA: The acute respiratory distress syndrome N Engl J Med 2000, 342:1334-1349 Abraham E: Neutrophils and acute lung injury Crit Care Med 2003, Suppl:S195-S199 ... colony-stimulating factor and alpha-chemokines in relation to serum levels, pulmonary neutrophilia, and severity of lung injury in ARDS Chest 2004, 125:212-219 Colletti LM, Green M: Lung and liver injury following...

Ngày tải lên: 12/08/2014, 20:20

... early-stage patients with acute respiratory distress syndrome • In patients with early-stage acute respiratory distress syndrome of suspected non-infectious origin, open lung biopsy may have a high ... and Blood Institute Acute respiratory Distress Syndrome (ARDS) Clinical Trials Network: Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome N Engl J Med 2006, ... diagnostic yield rate • The role of open lung biopsy in patients with acute respiratory distress syndrome needs to be investigated in prospective, randomized and controlled clinical trials Authors'...

Ngày tải lên: 13/08/2014, 01:20

... mechanical ventilation, and admission scorings were extracted from the ICU database To assess the severity of illness and ARDS, the Lung Injury Score and the Acute Physiology and Chronic Health Evaluation ... health, vitality, social function, emotional function and mental health), comparing between patients with acute respiratory distress syndrome and age- and gender-matched healthy controls Significant ... PTSS-10 score below the cutoff score; APACHE, Acute Physiology and Chronic Health Evaluation; ICU, intensive care unit; ARDS, acute respiratory distress syndrome; ECMO, extracorporeal membrane oxygenation...

Ngày tải lên: 13/08/2014, 03:20