influence of airflow rate and starting materials 129

Particle development for drug delivery

Particle development for drug delivery

... Speed and Starting Materials 126 A3.3 Influence of Airflow Rate and Starting Materials 129 A3.4 Influence of the Length of Grinding Zone and Starting Materials 131 A3.5 Relative Importance of the ... Process 76 B1.1.1 Influence of Beater Rotational Speed 79 B1.1.2 Influence of Classifier Wheel Rotational Speed 79 B1.1.3 Influence of Airflow Rate 79 B1.1.4 Influence of the Length of Grinding Zone ... Process 170 C2.1 Influence of Classifier Wheel Rotational Speed 170 C2.2 Influence of Starting Material 179 C2.3 Influence of Airflow Rate 180 C3 Complementary Roles of D50 and D99 181 D Nifedipine...

Ngày tải lên: 17/09/2015, 17:19

284 506 0
Research " Essays on the Equilibrium Valuation of IPOs and Bonds " pdf

Research " Essays on the Equilibrium Valuation of IPOs and Bonds " pdf

... E(RS ) ¡ Á2 (1 ¡ ») ¡ Á2 (1 + a + b)´; (1.2) where Rj is the rate of return of asset j, RS is the rate of return of the market portfolio and is de…ned as RS ´ ¯j ´ cov(Rj ;RS ) var(RS ) , P1 P1 +P2 ... securities) of IPOs IPO residual risk acts as a source of systematic risk and is priced in equilibrium From the point of view that innovation is the source of sustained economic growth and economic ... is de…ned as the negative of the ratio of the total number of shares available for short sale over the total number of shares outstanding IPO shares available Mauer and Senbet (1992) provide...

Ngày tải lên: 07/03/2014, 02:20

152 365 0
Báo cáo khoa học: Equilibrium distribution of skeletal actin–tropomyosin– troponin states, determined by pyrene–tropomyosin fluorescence potx

Báo cáo khoa học: Equilibrium distribution of skeletal actin–tropomyosin– troponin states, determined by pyrene–tropomyosin fluorescence potx

... cS1 and cA are S1 and actin concentrations, respectively Reverse rates of the reactions k)1, k)2, a)T, and a)B were assumed from Chen et al [37], and forward rates were calculated from K1, KB and ... concentration of i (lm); and Fmax and Fmin are the maximum and minimum values of intensity, respectively Modeling experimental results Light scattering was used to measure the binding of S1 ADP to actin and ... and p2 are fractions of actin units in the inactive and active states, respectively; hI and h2 are fractions of actin containing bound S1 in the inactive and active states, respectively; K1 and...

Ngày tải lên: 07/03/2014, 09:20

13 306 0
An Equilibrium Model of Rare-Event Premia and Its Implication for Option Smirks potx

An Equilibrium Model of Rare-Event Premia and Its Implication for Option Smirks potx

... are examined by Liu and Pan (2003), Liu, Longstaff, and Pan (2003) and Das and Uppal (2001) Dufresne and Hugonnier (2001) study the impact of event risk on pricing and hedging of contingent claims ... include Gilboa and Schmeidler (1989), Epstein and Wang (1994), Anderson, Hansen, and Sargent (2000), Chen and Epstein (2002), Hansen and Sargent (2001), Epstein and Miao (2003), Routledge and Zin (2002), ... types of random shocks One is a standard diffusive component, and the other is pure jump, capturing rare events with low frequency and sudden occurrence While the probability laws of both types of...

Ngày tải lên: 07/03/2014, 10:20

34 500 0
Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf

Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf

... (0.6 and 2.4 lM, 100 lL) equilibrated in buffer and M GdnHCl was loaded onto the column pre-equilibrated with 50 mM Tris/HCl buffer containing the same concentration of GdnHCl, pH 7.5 Calibrated ... activity of d2-crystallin was monitored as a function of the appearance of fumarate at 240 nm Tryptophan fluorescence was measured by the emission spectra at an excitation wavelength of 295 nm ... ðVe À V0 Þ=ðVt À V0 Þ where, Ve is the elution volume of the protein elution peak and Vt and V0 are the total volume and the void volume of the column, respectively Analytical ultracentrifugation...

Ngày tải lên: 08/03/2014, 08:20

8 426 0
Báo cáo khoa học: Using directed evolution to improve the solubility of the C-terminal domain of Escherichia coli aminopeptidase P Implications for metal binding and protein stability pptx

Báo cáo khoa học: Using directed evolution to improve the solubility of the C-terminal domain of Escherichia coli aminopeptidase P Implications for metal binding and protein stability pptx

... number of mutations per gene The implication of this observation is that the effects of most mutations are small compared with those of G270V, E406G, and R166G Changes at the surface of the protein ... 50 lgÆmL)1 kanamycin and increasing concentrations of TMP for the three rounds of evolution For the first round, lgÆmL)1 TMP was used, and in the second and third rounds, 10 and 20 lgÆmL)1 TMP were ... Kinetic and crystallographic analysis of mutant Escherichia coli aminopeptidase P: C-terminal domain of E coli aminopeptidase P insights into substrate recognition and the mechanism of catalysis...

Ngày tải lên: 23/03/2014, 07:20

10 538 0
Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx

Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx

... (a) the role of the N-terminal extension; (b) the role of the D to N mutation; and (c) the role of the sequence and length of the C-terminal extension To address whether presence of extra residues ... conditions (see Materials and methods) The cell pellets were sonicated and the resulting lysates were loaded onto pre-equilibrated amylose columns Sufficient and equivalent amounts of amylose resin ... issue that solubility of fusion proteins is not necessarily indicative of either proper folding or of increased solubility of the protein of interest We propose that the success of fusion protein...

Ngày tải lên: 23/03/2014, 21:20

5 436 0
báo cáo hóa học:" Research Article Strong Convergence for Mixed Equilibrium Problems of Infinitely Nonexpansive Mappings Jintana Joomwong" pot

báo cáo hóa học:" Research Article Strong Convergence for Mixed Equilibrium Problems of Infinitely Nonexpansive Mappings Jintana Joomwong" pot

... element of EP Θ and the set of fixed points of nonexpansive mappings Furthermore,Yao et al 8, 10 introduced an iterative scheme for finding a common element of EP Θ and the set of fixed points of finitely ... element of the set of solutions of an equilibrium problem and the set of common fixed point of infinitely many nonexpansive mappings in H Let {Tn }∞ be a sequence of n nonexpansive mappings of C into ... suggest and analyze an iterative scheme for finding a common element of the set of fixed point of infinitely nonexpansive mappings, the set of solutions of an equilibrium problem and the set of solutions...

Ngày tải lên: 21/06/2014, 10:20

22 306 0
Báo cáo hóa học: "Research Article Stability of Equilibrium Points of Fractional Difference Equations with Stochastic Perturbations" pdf

Báo cáo hóa học: "Research Article Stability of Equilibrium Points of Fractional Difference Equations with Stochastic Perturbations" pdf

... region one can see the regions of stability of the point of equilibrium x1 that were obtained by condition 3.3 grey and green regions and by conditions 3.4 , 3.5 cyan and green regions Stability ... dynamics of xn Journal of Difference Equations and Applications, vol 9, no 8, pp 731–738, 2003 E Camouzis and G Papaschinopoulos, “Global asymptotic behavior of positive solutions on the system of rational ... clear that the stability of the trivial solution of 2.2 is equivalent to the stability of the equilibrium point of 2.1 Together with nonlinear equation 2.2 we will consider and its linear part k...

Ngày tải lên: 22/06/2014, 11:20

21 230 0
Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx

Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx

... aspects of the laboratory work, analyzed the data and prepared the manuscript SK, SA, MW and CB participated in the collection of clinical data and the recruitment of patients into the study UW and ... the patient and the control cohort and all analyzed subgroups The distribution of genotypes and the resulting allele frequencies of the variant PTPN22 1858T allele in RA patients and healthy ... in RA patients The CT and TT genotype was present in 37.9% of patients and 19.2% of healthy controls, resulting in an OR of 2.57 (95% CI 1.85–3.58, p < 0.001) Carriage of a homozygous TT genotype...

Ngày tải lên: 09/08/2014, 08:22

7 421 0
Báo cáo y học: "Explicit equilibrium modeling of transcription-factor binding and gene regulation" pdf

Báo cáo y học: "Explicit equilibrium modeling of transcription-factor binding and gene regulation" pdf

... set of sequences and the thermodynamics and specificity of binding (see Materials and methods for a fuller discussion) [9] A variation on this idea treats the PWM as a predictor of affinity and ... (see Materials and methods) and have used this model to study the interaction of yeast transcription factors Ndt80p and Sum1p Ndt80p is an activator of genes expressed during the middle stage of ... positiondependent models that define the size and shape of regulatory regions and describe the nature of cooperative and competitive interactions (see Materials and methods) These functions can be as...

Ngày tải lên: 14/08/2014, 14:22

10 281 0
Thermochemical equilibrium modeling of biomass downdraft gasifier: Stoichiometric models

Thermochemical equilibrium modeling of biomass downdraft gasifier: Stoichiometric models

... the development of the present work The molar distribution of CO/CO2 and CO/H2 as a function of the temperature of the synthesis gas produced by the gasification of woody biomass materials in downdraft ... Determination of the enthalpy of formation of feedstock is the second step, and knowledge of the HHV or LHV (low heating value) of the feedstock is necessary Applying the HHV definition the enthalpy of formation ... (2014) 189e201 presented here: 52.28% of C, 6.61% of H, 41.05% of O, 0.1% of N, 0.01% of S, 1.54% of Ash In work by Leoneti et al [60] it is stated that one of the possible applications for the...

Ngày tải lên: 01/08/2016, 09:31

13 275 0
Study on the Photolytic Mechanisms of Red 141 Dye Wastewaters with an 185nm Vacuum-UV lamp

Study on the Photolytic Mechanisms of Red 141 Dye Wastewaters with an 185nm Vacuum-UV lamp

... requirements of the VUV photolysis of water according to Eq (1) are related to the formation of high local concentration of hydroxyl radicals (OH.) and a series of other species (Gonzalez and Braun, ... both generated from the excitement of H2O and oxygen molecules The pseudo-first order reaction rate constants of the three driving forces are referred to kuv.only, k OH·H2O, and kOH·O2 and also ... those in the VUV/N2 and VUV/O2 systems because of OH generated from the photolysis of H2O and O2 are almost scavenged by the adding t-butanol In addition, the decomposition rates of Red 141 conducted...

Ngày tải lên: 05/09/2013, 09:08

9 470 0
Tài liệu THE PRINCIPLES OF CHEMICAL EQUILIBRIUM doc

Tài liệu THE PRINCIPLES OF CHEMICAL EQUILIBRIUM doc

... energy of a pair of molecules of types i andj a:, Mole fraction of ith species in vapour phase %+,%- Charges of positive and negative ions respectively in units of the proton charge « Coefficient of ... surface of the catalyst It is therefore a problem of rates and not of equilibria The theory of equilibria, based on thermodynamics, is much simpler, and also more precise, than any theory of rates ... differential of a function of state and its integral is Us- UA• which depends only on the initial and final states A and B; dq and dw, on the other hand, are not the differentials of a function of state,...

Ngày tải lên: 12/02/2014, 16:20

514 468 0
Tài liệu Correspondence & Conversations of Alexis de Tocqueville with Nassau William Senior from 1834 to 1859, Vol. 2 docx

Tài liệu Correspondence & Conversations of Alexis de Tocqueville with Nassau William Senior from 1834 to 1859, Vol. 2 docx

... the caprice of one man, a foreigner by race and by education, and of a set of military ruffians and of infamous civilians, fit only to have formed the staff and the privy council of Catiline ... conversation; every individual stands defenceless and insulated, in the face of this unscrupulous executive, with its thousands of armed hands and its thousands of watching eyes The only opposition ... hope of undisturbed peace and progressive civilisation and prosperity An alliance with England was one of the favourite dreams of the first Napoleon He believed, and with reason, that England and...

Ngày tải lên: 18/02/2014, 08:20

126 543 0
Tài liệu Báo cáo khoa học: Mechanism of dihydroneopterin aldolase NMR, equilibrium and transient kinetic studies of the Staphylococcus aureus and Escherichia coli enzymes docx

Tài liệu Báo cáo khoa học: Mechanism of dihydroneopterin aldolase NMR, equilibrium and transient kinetic studies of the Staphylococcus aureus and Escherichia coli enzymes docx

... HPO, the oxidized form of HP These measured rate constants are reliable and accurate, because of (a) the high quality of the stopped-flow data as illustrated in Figs and and (b) the consistency ... the measurements of both equilibrium and kinetic constants of the physical steps by equilibrium and stopped-flow fluorimetric analysis and the determination of the rate constants of the chemical ... inhibitors NP and MP To assess the differences in the rate constants of the reduced and oxidized pterins, we also measured the association and dissociation rate constants of HPO and compared them...

Ngày tải lên: 19/02/2014, 00:20

13 479 0
On the Segregation of Genetically Modified, Conventional, and Organic Products in European Agriculture: A Multi-market Equilibrium Analysis doc

On the Segregation of Genetically Modified, Conventional, and Organic Products in European Agriculture: A Multi-market Equilibrium Analysis doc

... g ao sn e sn of GM food with conventional and quality-enhanced products, mandates the labelling and traceability of GM products, and allows only a stringent adventitious presence of GM content ... the introduction of GM products, and endogenise the price of land and the reward to the additional efforts supplied by farmers The model is calibrated to replicate observed data of EU agriculture, ... the effects of IP (of the superior products) and the impact of labelling and traceability requirements (on the inferior product).6 The model Based on the foregoing, the demand, supply and equilibrium...

Ngày tải lên: 05/03/2014, 20:20

36 573 0
24,185 OUTLETS - The number of JApAN pOST BANk outlets in Japan docx

24,185 OUTLETS - The number of JApAN pOST BANk outlets in Japan docx

... Average of Japan’s Mega Banks 1,750 Number of Municipalities*2 26,146 25,786 JAPAN POST BANK Total of Six Major City Banks NUMBER OF DOMESTIC OUTLETS*1 NUMBER OF DOMESTIC CD ATMS (As of March ... buildings that are separate from post office facilities At post of- • ATM service fices, which are operated by JAPAN POST NETWORK, employees handle bank agency operations as one facet of counter operations ... including branches, ATMs, and • Broad base of customers  • Steady, conservative investment  • Maintenance of low-cost  extending to all generations  operations and all regions of Japan the Internet...

Ngày tải lên: 06/03/2014, 10:20

8 377 0
AN ECONOMIC HISTORY OF THE ENGLISH POOR LAW 1750-1850 pptx

AN ECONOMIC HISTORY OF THE ENGLISH POOR LAW 1750-1850 pptx

... adoption of outdoor relief policies in the 1770s and 1780s and for the significant differences in the administration of relief between the southeast of England and the west and north, and it analyzes ... increase in labor demand for hedging and ditching, and a long-run increase in labor demand by the cultivation of commons and waste, and the adoption of new cropping systems that often followed However, ... out-migration rates in England from 1816 to 1831 were similar to out-migration rates in developing countries during the 1960s and 1970s Further evidence of labor mobility, and of the importance of London...

Ngày tải lên: 07/03/2014, 03:20

311 406 0
Báo cáo Y học: The folding of dimeric cytoplasmic malate dehydrogenase Equilibrium and kinetic studies doc

Báo cáo Y học: The folding of dimeric cytoplasmic malate dehydrogenase Equilibrium and kinetic studies doc

... standard procedure of s-MDH assay, monitoring the rate of the fall of absorbance of 0.2 mM NADH at 340 nm at 25 °C in 150 mM sodium phosphate buffer (pH 7.6) containing 0.5 mM oxaloacetate and ... expands and remains more Fig Equilibrium ‘dissociation and unfolding’, and ‘association and refolding’ of s-MDH, as measured by size-exclusion HPLC Experimental conditions were as described in Materials ... characterization of the intermediates to understand the structural changes involved in each transition, and (b) analysis of the kinetic mechanism that enables determination of the rate constants of individual...

Ngày tải lên: 08/03/2014, 23:20

11 399 0
w