... use of these drugs, however, absolute rates for these potential events are high [12] Premarketing understanding of major biologic effects of new therapies and large carefully performed studies of ... sophistication on the part of physicians and the public in understanding the inevitable competing risks and benefits of medical therapy and the inherent uncertainties in the current paradigm of drug development ... approval of celecoxib and rofecoxib was cost After publication of the results of the VIGOR trial, comparative safety became less clear between nonselective NSAIDs and coxibs Results of the placebo-controlled...
Ngày tải lên: 09/08/2014, 07:20
... apart from diclofenac, meloxicam and etodolac, with values of about 0.5 to 0.9 ml/day (Table and Figure 2) Rofecoxib and etoricoxib also had low mean daily faecal blood loss of 0.8 and 0.9 ml/day ... reports of 47 randomized trials (Additional file includes details of the trials, including trial design; nature of participants, and their sex, age and any illness; faecal blood loss results; and ... nonsteroidal anti -inflammatory drug, cyclooxygenase-2 inhibitor, as well as the individual names of common drugs, including ibuprofen, diclofenac, naproxen, indomethacin, ketoprofen, rofecoxib, celecoxib,...
Ngày tải lên: 09/08/2014, 10:22
Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
... isoforms by the excision of the prosegment and of most of the PSI [21] Conversely to what has been found in vivo [31], heavy and light chains of the processed forms of recombinant cyprosin are ... N-terminal of the mature enzyme and by the ÔflapÕ The anchorage of the prosegment and of part of the N-terminus in the active site cleft is made by ionic interactions established between Lys11/Tyr13 of ... mechanisms of degradation of pathogenesis-related proteins in plants Plant Physiol 95, 616–622 Guevara, M.G., Oliva, C.R., Machinandiarena, M & Daleo, G.R (1999) Purification and properties of an aspartic...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: 1,5-Diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases ppt
... (fragmentation: m/z 317.3, 305.2, 291.1, 253.2 and 240.1), 350.2 (fragmentation: m/z 333.2 and 307.1) and 431.3 (fragmentation: m/z 414.3, 388.3 and 337.1) MALDI-TOF-MS of the separated peak provided a single ... 18 19 20 21 and oxidative half-reactions and the role of copper ions in plant and mammalian copper-amine oxidases Eur J Inorg Chem 1, 35–42 Medda, R., Padiglia, A & Floris, G (1995) Plant copper-amine ... oxidized by an excess of GPAO (500 nkat) in 0.1 M potassium phosphate buffer, pH 7.0, in the presence of catalase (200 U) and 2.5 mM ABA After h of incubation at 30 °C, mL of 15% trichloroacetic...
Ngày tải lên: 19/02/2014, 16:20
WHY DOES THE WORLD STAY GREEN? Nutrition and survival of plant-eaters doc
... icefields, plants grow on and cover nearly all surfaces of the Earth They make up some 99.9 per cent of the weight of living things on Earth: only a tiny fraction of life consists of animals If plants ... some of the ancient cities found buried deep in the jungles of Central and South America Nor are plants confined to dry land Myriads of plants, from singlecelled plankton to seagrasses and huge ... other inedible plants is remote To our eyes many species of plants are widely scattered and hard to The green world find among other sorts of plants However, this strategy of the plants has been...
Ngày tải lên: 22/03/2014, 19:20
chemical engineering design principles, practice and economics of plant and process design
... always refer to the original source references of laws, standards, and codes of practice, as they are updated frequently All of the costs and examples have been put on a U.S basis, and examples have ... of international standards The European countries used to maintain their own national standards, but these are now being superseded by common European standards Lists of codes and standards and ... Capacity 92 Enthalpy of Mixtures 94 Enthalpy-Concentration Diagrams 95 Heats of Reaction 98 Standard Heats of Formation 101 Heats of Combustion 102 Compression and Expansion of Gases 104 Energy...
Ngày tải lên: 01/04/2014, 11:33
báo cáo khoa học: "MeRy-B: a web knowledgebase for the storage, visualization, analysis and annotation of plant NMR metabolomic profiles" potx
... were used 1) creation of the users account and project, 2) population of the database with the user’s data, and 3) analysis and visualization of the user’s data The aim of the tomato study was ... contributions ADD and AM initiated the project HFD, DJ and LG designed the DB LG and DJ designed the web interface and implemented the DB and associated tools and developed the source code of the web ... such as NMR, is often required for further characterization of specific metabolome changes in terms of structure [30] A major advantage of H-NMR is that the profiles obtained are often comparable,...
Ngày tải lên: 11/08/2014, 11:21
báo cáo khoa học: " Identification and characterization of plant Haspin kinase as a histone H3 threonine kinase" ppsx
... Thr3 and Thr11 in planta AtHaspin is involved in cell division Because of the presence of the plant cell wall, cell division, including cytokinesis, is more complex in plants than in animals A plant- specific ... analogues of CPC components exist in plants Further analyses of the substrates of AtHaspin and their downregulating mechanisms will provide insights into the regulation of cell division during plant ... phosphorylation of histone H3 is correlated with the condensation of plant mitotic chromosomes Plant J 1999, 18(6):675-679 Gernand D, Demidov D, Houben A: The temporal and spatial pattern of histone...
Ngày tải lên: 11/08/2014, 11:22
Scientific report: "The awareness of people about the risks of plant protection drugs in vegetable production: case studies in Hanoi and Thai Binh" ppsx
... perception of pesticide risks and the current status of human and environmental risks caused by pesticides in the the selected distinct case studies of vegetable production in Hanoi city and Thai ... province The overall objective of this paper is to 1) examine local people’s perception of level of pesticide risks to human and environment, their causes and risk group; and 2) draw recommendations ... as means, standard deviation, frequencies and cross tab were employed to describe the current situation of people’s perception of risks RESULTS AND DISCUSSION 3.1 People’s perception of pesticide...
Ngày tải lên: 06/08/2014, 18:22
Báo cáo y học: "Prescription channeling of COX-2 inhibitors and traditional nonselective nonsteroidal anti-inflammatory drugs: a population-based case–control study" pot
... Conversely, the majority of COX-2 inhibitors were prescribed at standard anti -inflammatory dosages (65.3% of celecoxib and 73.0% of rofecoxib prescriptions) A relatively high proportion of COX-2 inhibitors, ... users and 15.7% among nonselective NSAID users The great majority of NSAIDs were prescribed by general practitioners (85.9% of traditional nonselective NSAIDs, 85.3% of celebrex and 88.3% of rofecoxib ... NSAID, nonsteroidal anti -inflammatory drug R339 Arthritis Research & Therapy Vol No Moride et al dosages in excess of standard recommendations (31.2% of celecoxib and 8.8% of rofecoxib prescriptions)...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "A multicentre case-control study of nonsteroidal anti-inflammatory drugs as a risk factor for severe sepsis and septic shock" docx
... fasciitis and non steroidal anti -inflammatory drugs: a case series and review of the literature N Z Med J 2001, 114:3-6 Holder EP, Moore PT, Browne BA: Nonsteroidal anti -inflammatory drugs and necrotising ... NSAIDs Aspirin Site of infection: lung (n = 71)a NSAIDs Aspirin Site of infection: urinary tract (n = 30)a Site of infection: skin and soft tissue (n = 16)a NSAIDs Aspirin Site of infection: other ... between NSAID use and increased risk for sepsis during bacterial infection First, the sites of infection and micro-organisms that we identified, especially the low incidence of skin and soft tissue...
Ngày tải lên: 13/08/2014, 16:20
Textile and Apparel Barriers and Rules of Origin in a Post-ATC World
... largest importer of textiles and apparel, and it accounted for 17.0 percent of world imports of these goods in 2005 This high value of imports occurred in spite of U.S textile and apparel import ... 34 (1): 141–166 Estevadeordal, Antoni and Kati Suominen 2006 “Mapping and Measuring Rules of Origin Around the World.” In The Origin of Goods: Rules of Origin in Regional Trade Agreements, ed ... Representative 2005 “Memorandum of Understanding Between the Governments of the United States of America and the People’s Republic of China Concerning Trade in Textile and Apparel Products.” (November...
Ngày tải lên: 12/04/2013, 16:17
ảNH HƯởNG CủA MậT Độ GIEO TRồNG ĐếN CáC CHỉ TIÊU SINH Lý Và NĂNG SUấT CủA GIốNG BÔNG VN35KS Effect of Plant Density on Cotton Physiological Characters and Seed
... tr.106-108 Ashley D.A., Doss B.D., and Bennett O.L (1965) Relation of cotton leaf area index to plant growth and fruiting, Agronomy Journal 57, pp 61-64 Gomez K Wanchai A and Gomez Arturo A (1984) Statistical...
Ngày tải lên: 28/08/2013, 14:15
Design and development of major balance of plant components in solid oxide fuel cell system
... any SOFC system, the performance of the INER SOFC system is dependent not only on the design and operating conditions of the fuel cell stack, but also on the design and operating conditions of ... provided by the anode off-gas given an anode off-gas temperature of less than 650 oC, a cathode off-gas temperature of less than 390 oC, and a flame barrier temperature of less than 700 oC However, ... SOFC BOP system (S/C=1.7, O/C=0.3, fuel utilization = 64.2%, electrical conversion efficiency = 44%) Design of SOFC BOP components The BOP components of a SOFC system account for between 50% and...
Ngày tải lên: 05/09/2013, 16:10
Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)
... of 0.4 mL of blank blood and 0.4 mL of IS- containing pentane solution in a glass vial with a Teflon-septum screw cap, which has been cooled with ice, and vortex-mixed for s; a 3-µL aliquot of ... Assessment and some comments on the method > Figure 8.1 shows gas chromatograms of isobutyl nitrite (injected amount µg) and isobutyl alcohol (injected amount 10 µg); they appeared at 3.4 and 7.4 of ... detection limits of isobutyl nitrite and isobutyl alcohol in liquid specimens were 62 ng and 1.9 µg/mL, respectively [7] > Figure 8.2 shows EI mass spectra of isobutyl nitrite (A) and isobutyl alcohol...
Ngày tải lên: 18/10/2013, 00:15
Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)
... analysis of DAEMS, various concentrations of DAEMS are spiked into blank serum specimens containing a fixed amount of DAEMO (IS) each and extracted as described before Since the base peaks of DAEMS and ... Trace Analysis of Chemical Warfare Agents An Approach to the Environmental Monitoring of Nerve Agents Ministry of Foreign Affairs of Finland, Helsinki, pp 27, 28, 37–39, 59–64, 72–79 and 90–99 2) ... serum (a) a total ion chromatogram (TIC) and a mass chromatogram; (b) an EI mass spectrum of DAEMS; (c) a CI mass spectrum of DAEMS Poisoning case, and toxic and fatal concentrations VX is much less...
Ngày tải lên: 18/10/2013, 00:15
Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)
... 188 Cannabinoids and their metabolites GC analysis of cannabinoids in plant specimensa Reagents and their preparation • • • Extraction and purification of cannabinoids [3]: Cannabis ... 2.4 Mass spectra of the methyl ester plus TMS and TMS derivatives of ∆9-THC-11-oic acid The Substance Abuse and Mental Service Administration (SAMSA) in USA set the cutoff value of ∆9-THC-11-oic ... Methods for analysis of cannabis and its components In: The Pharmaceutical Society of Japan (ed) Standard Methods of Chemical Analysis in Poisoning – With Commentaries, 4th edn., Nanzando, Tokyo, pp...
Ngày tải lên: 24/10/2013, 19:15
Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)
... analysis is made by the comparison of the retention time of a peak of a specimen with that of the authentic standard and also by the confirmation of the absence of such a peak in a blank specimen ... HPLC analysis Reagents and their preparation • • Standard solutions of morphine for a calibration curve (2, and 20 µg/mL): see “Reagents and their preparation”, above of GC and GC/MS analysis section ... of morphine, codeine and 6-acetylmorphine, the extraction is made as follows A 2-mL volume of urine is diluted 2-fold with purified water and mixed with 0.1 mL of the IS solution and 0.2 mL of...
Ngày tải lên: 24/10/2013, 19:15
Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)
... volume of the supernatant solution is transferred to a new polypropylene tube of the same type, followed by addition of 0.5 mL of concentrated sulfuric acid f and 0.5 mL of mesitylene Nitrate and ... addition of 20 mg of anhydrous sodium carbonate and vortex-mixed for After centrifugation at 3,000 rpm for min, 1- or 4-µL of the upper layer is injected into GC Various known amounts of nitrate and ... He; flow rate: 2.1 mL/min Procedures i Analysis of nitrate i ii iii iv v vi A 0.2-mL volume of a test specimen, 20 µL of IS solution and 0.2 mL of the saturated silver acetate solution e are placed...
Ngày tải lên: 24/10/2013, 19:15
Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)
... A and B, a 0.5-mL volume each of distilled water is added To cuvettes C and D, a 0.5-mL volume each of % potassium ferricyanide solution is added vi To cuvettes A and C, a 3-mL volume each of ... cuvettes to stand for min, the absorbances of cuvettes B and D at 630 nm are read using cuvettes A and C as references, respectively These readings are A2 and A4, respectively x The percentage of Met-Hb ... Assessment and some comments on the method The present method for analysis of Met-Hb in blood is simple and rapid, and is not interfered with by the coexistence of high concentrations of CO-Hb...
Ngày tải lên: 24/10/2013, 19:15