infections in patients with hematologic cancer

... not receiving colony growth factor support and in patients receiving mucotoxic regimens consisting of cytarabine plus anthracyclines This finding is consistent with the bowel being a principal ... established infections is unproven, it may be considered in the setting of profound neutropenia (ANC < 100/mcL) and in serious infections, including invasive fungal infection (Category 2B) in cases ... with increased mortality occurring in older patients, in patients with poorly controlled malignancy, and in cases in which Candida (Torulopsis) glabrata was isolated.6 However, blood stream infection

Ngày tải lên: 10/03/2017, 19:28

... Twenty-eight patients had previously been treated with hepatic surgery, 54 with prior systemic chemotherapy, including FOLFOX in 35 patients, FOLFIRI in 15, Avastin in 37 patients, and other biologics in ... treated with Irinotecan drug eluting beads with liver dominant hepatic metastasis after fail-ing standard chemotherapy b) Overall Survival of patients treated with Irinotecan drug eluting beads with ... report but including at least 13 deaths [...]... been involved in drafting the manuscript or revising it critically for important intellectual content MR have been involved in drafting the

Ngày tải lên: 09/08/2014, 04:21

... pathway activity in three subgroups of patients: SLE patients with one or more major infections, patients with SLE who experienced minor infections only, and SLE patients without any infections (Figure ... following subgroups were considered: SLE patients with one or more major infections versus SLE patients without major infections, SLE patients with one or more major infections versus patients ... obtain information on documented infections since diagnosis of SLE. Major infections were defined as infections requiring hospital admission and intravenous administration of antibiotics. In total,

Ngày tải lên: 09/08/2014, 08:23

... treatment with TNF antagonists may reduce the incidence of emerging opportunistic infections. 51 52 Vaccinations (Table 2) Vaccines are certainly underutilised in patients with IBD. In the USA, in 2005, ... in the case of lymphopenia, CD4 lymphocyte count c C-reactive protein c Urine analysis in patients with a history of urinary tract infection, and urinary symptoms c VZV serology in patients without ... bacterial infections. 87–91 PCT has not been formally tested in IBD patients with suspected infections, and cannot be recommended in routine practice. Nevertheless, given the promising interest in this

Ngày tải lên: 13/08/2014, 09:45

... described in Methods, we computed a continuous prognostic score (PS) based on the grouping defined in the training set A Cox proportional hazards model on the training set (CoxTrain) using PS to ... protein synthesis machinery including phosphorylated S6 ribosomal protein and 4EBP1, a group with overexpression of stromal markers including collagen VI, CD31 and caveolin1, and a group defined ... 168) in two cohorts of patients with primary breast cancer A score was constructed using ordinal logistic regression to quantify the probability of recurrence in the training set and tested in

Ngày tải lên: 13/08/2014, 13:20

... common cancer affecting women in Scotland, accounting for 28% of all cancers in the Scottish female population (World Cancer Research Fund 2013) Breast cancer in Scotland has increased ... of a clinically significant change in hand size with treatment. The studies would support the use of the figure of eight method for monitoring hand oedema in patients presenting with BCRL. ... method, the subject numbers with this increase and patients with difficulty in achieving the standardised position in the volumeter page 109 Table 14: The change in affected hand size for the

Ngày tải lên: 22/12/2014, 21:42

... with clinical outcome in patients with CRC treated with 5-FU In a study of 221 CRC patients treated with 5-FU, an improvement in overall survival was seen in patients with ... 82 OTHER AfiAm AfiAm Afica-indian Afica-indian AfrAm AfrAm AfrAm Arab Arab Argentina Argentina Brazil Canada (Inuit) Croatian HispAm HispAm India India Indian Indian Indian Indonesia Mexico S Africa Sub ... in patients with advanced CRC In a retrospective study of patients with metastatic CRC, the response rate of patients receiving oxaliplatin/5-FU was significantly higher in patients

Ngày tải lên: 04/10/2015, 15:58

... agreement with all of his patients Such properties eliminate potential confounding variables and increase the study’s internal validity Frequency of agreement with patients (%) low on all symptoms In ... distress thermometer in Chinese cancer patients Chinese Journal of Cancer Research, 23(1), 54–58 doi: 10.1007/s11670-011-0054-y Trask, PC (2004) Assessment of depression in cancer patients JNCI Monographs, ... establishing directionality of associations, the findings clearly emphasize the role of relational skills in detecting these symptoms They demonstrate the value of using structured screening instruments

Ngày tải lên: 10/01/2020, 13:19

... building The included patients were divided into the training and validation cohorts by a ratio of 7:3 using randomstratified grouping In the training cohort, support vector machine (SVM) and principle ... in this study was effective in predicting treatment response to neoadjuvant chemotherapy and stratifying patients? ?? prognosis for gastric cancer These findings may help clinicians in identifying ... were higher in patients with no response to neoadjuvant chemotherapy, which indicated that the intratumoral heterogeneity was more apparent in these patients than in the responding patients Many

Ngày tải lên: 30/05/2020, 21:54

... of patients who underwent chemotherapy [43–45] Individual nutritional counseling has also been demonstrated to be important in maintaining the nutritional status [46] In line with our findings, ... during NAC predicts poor prognosis Thus, maintaining the nutritional status during NAC may result in better treatment outcomes in patients with breast cancer Keywords: Prognostic nutritional index, ... (89.5%) had invasive ductal carcinoma; 12 patients (6.3%), invasive lobular carcinoma; and patients (4.2%), other special types As for intrinsic subtype, 107 cases (56.0%) were luminal Table Clinicopathologic

Ngày tải lên: 17/06/2020, 03:19

... (irAEs) caused by immune checkpoint inhibitors were associated with clinical benefit in patients with melanoma or lung cancer In advanced gastric cancer (AGC) patients, there have been few reports ... events (death) within months (Fig 2) Even in this subgroup, the PFS and OS were significantly longer in patients experiencing irAEs After excluding the patients who had events within one and months, ... cancer has been continuously decreasing, it remains one of leading causes of cancer deaths worldwide and was reported to be especially high in East Asia [1, 2] In Japan, gastric cancer is the most

Ngày tải lên: 17/06/2020, 18:16

... comparing circulating protein levels in patients with COPD and patients with lung cancer with and without COPD One-way MANCOVA was performed on two groups (COPD and Lung cancer with and without ... smokers in the group of LC patients with COPD (43%) than in LC patients without COPD (28%) and COPD patients without cancer (24%) Almost 10% of LC patients without COPD had never smoked Patients with ... study, including patients with NSCLC and patients with COPD Methods The aim of this study is to identify differences in the selected serum markers in patients with NSCLC and patients with COPD In

Ngày tải lên: 03/07/2020, 00:50

... content   in   patients   with   colon   cancer   before   and   after   radical   surgery”? ?with? ?the following goals:  Study   the   Malondialdehyde   content   in   patients   with   colon   cancer? ?who underwent radical surgery treatment ... ­? ?Patients? ?in? ?Stage I, II, III correspondingly were 11? ?patients? ?(14.9%),  32? ?patients? ?(43.2%) and 31? ?patients? ?(41.9%). The rate of? ?patients? ?with? ? lymph node metastasis: 41.9%, invasion T4: 33? ?patients? ?(44.6%) ... ­ Laparoscopic surgery: 42? ?patients? ?and open surgery: 32? ?patients,   Colostomy: 7? ?patients? ?(9.5%). Expanding surgery: 14? ?patients? ?(18.9%),  of which 5? ?patients? ?with? ?total colectomy. Most? ?patients? ?with? ?expanding  surgery were those who underwent open surgery  (13/14)

Ngày tải lên: 23/07/2020, 00:36

... the tumor, including cases of ductal carcinoma in situ, invasive ductal carcinoma, tubular carcinoma, mucinous carcinoma, papillary carcinoma, cribriform carcinoma, invasive lobular carcinoma and ... are being incorporated into screening programs Interval breast cancer is defined as primary breast cancer diagnosed in a woman who had a screening test, with or without further assessment, with ... lobular carcinoma in situ Symptomatic breast cancer will be included, as well as screened and interval breast cancer The breast cancer screening program is public and universal in Spain Following the

Ngày tải lên: 23/07/2020, 23:57

... 10 Cunningham et al.’s trial which specifically included patients with gastroesophageal cancer, we noted that patients receiving NAC were associated with a nonsignificant increase in the incidence ... have been decreasing in the past few years, gastric cancer (GC) remains the fourth most common malignancy in world [1] The incidence of early gastric cancer were highest in China, Japan, and Korea, ... across Europe and Australasia and is increasing accepted in North America [5] D2 Gastrectomy with adjuvant therapy is practised routinely in Asia, whereas patients with advanced gastric tumors needed

Ngày tải lên: 24/07/2020, 00:33

... ratio into arms A, B, and C: A (intervention) – a brief CBT-based psychosocial intervention + early PC combined with standard cancer treatment; B (intervention) – early PC combined with standard cancer ... systematically combined with early PC In the present article, we present the impact of interventions on patients? ?? emotional domain over time and in greater detail on intervention day 90 measured using several ... randomized phase II clinical trial with two intervention arms and one control group Patients with advanced cancer starting palliative chemotherapy and who met the selection criteria were included The

Ngày tải lên: 06/08/2020, 05:03

... Tissue Tissue Tissue Tissue Tissue Test sample Protein Protein Protein Protein Protein Protein Protein Protein Protein mRNA Protein Protein Protein Test content PCR IHC IHC ELISA IHC IHC IHC IHC ... rate in patients with glioma [30] Similar results were also found in patients with gastric cancer [31], hepatocellular carcinoma [32], renal cancer [33], breast cancer [34], and oesophageal cancer ... 11 Inclusion criteria The inclusion and exclusion criteria included the following four aspects (1) Patients diagnosed with CRC (including colon cancer and rectal cancer) were eligible for inclusion

Ngày tải lên: 19/09/2020, 21:38

... imaging This finding revealed that patients with a high standardized uptake value (SUV) had a worse prognosis than individuals with low SUV This was confirmed in several types of cancer, including ... from the included studies were analyzed using Review Manager Software version 5.2 Results: Eight studies with 1080 patients were included The pooled HR for OS of six studies including 672 patients ... in Table and detailed information of the PET protocol is shown in Table Quality assessment of the enrolled studies The whole eight studies involving 1080 patients and the number of patients in

Ngày tải lên: 19/09/2020, 21:53

... radiotherapy in rectal cancer patients Methods: A prospective cohort study was conducted in 22 hospitals in Spain including 770 patients undergoing surgery for rectal cancer Study outcomes were disseminated ... especially striking in patients diagnosed with disseminated disease, suggesting that the disease is suspected and confirmed earlier in men than in women, both in cases referred from screening and those ... women) The remaining 2749 patients were included, 1979 with colon and 770 with rectal cancer All hospital Institutional Review Boards approved the study and all participants signed an informed consent

Ngày tải lên: 19/09/2020, 21:57

... occur in cancer patients Fibrinogen is an important hemostatic factor that regulates the hemostatic pathway Hyperfibrinogenemia is increasing recognized as an important risk factor influencing cancer ... preoperative serum fibrinogen as a biomarker for predicating tumor progression and survival of patients with GC Patients and methods: This retrospective study was conducted in GC patients who underwent ... BMC Cancer (2016) 16:480 DOI 10.1186/s12885-016-2510-z RESEARCH ARTICLE Open Access Serum fibrinogen levels are positively correlated with advanced tumor stage and poor survival in patients with

Ngày tải lên: 20/09/2020, 14:10