... pseudodiphtheriticum is part of the normal flora of the human pharynx and skin C xerosis is found on the skin, nasopharynx, and conjunctiva; C auris in the external auditory canal; and C striatum in the ... anterior nares and on the skin C jeikeium and C urealyticum are found in the axilla, groin, and perineum, particularly in hospitalized patients C ulcerans and C pseudotuberculosis infections have ... associated with the consumption of raw milk from infected cattle Specific Nondiphtherial Coryneforms C ulcerans This organism causes a diphtheria like illness and produces both diphtheria toxin and a dermonecrotic...
... either prosthetic or native valves and invasive pneumonia—have been identified only rarely Although C pseudodiphtheriticum may be isolated from the nasopharynx of patients with suspected diphtheria, ... a commensal of the human nasopharynx and skin but has been implicated as a cause of pharyngitis and chronic skin ulcers In contrast to the much more common pharyngitis causedby Streptococcus ... Biology and molecular epidemiology of diphtheria toxin andthe tox gene J Infect Dis 181(Suppl 1):S156, 2000 Kadirova R et al: Clinical characteristics and management of 676 hospitalized diphtheria...
... During the 1990s in the states of the former Soviet Union, a much larger diphtheria epidemic caused >150,000 cases and >5000 deaths Clonally related toxigenic C diphtheriae strains of the ET8 ... respiratory diphtheria occurs year-round but is most common during winter months The development of diphtheria antitoxin and diphtheria toxoid vaccine led to the near-elimination of diphtheria in Western ... leads to the optimal expression of diphtheria toxin, and these conditions are believed to be a mechanism of pathogenesis during human infection Epidemiology C diphtheriae is transmitted via the aerosol...
... the tonsils and present with "bull-neck" diphtheria, which results from massive edema of the submandibular and paratracheal region and is further characterized by foul breath, thick speech, and ... psoriasis, and venous stasis disease The lesions rarely exceed cm Figure 131-2 Cutaneous diphtheria due to nontoxigenic C diphtheriae on the lower extremity (From the Centers for Disease Control and ... diphtheria neuropathy is a noninflammatory demyelinating disorder mediated bythe exotoxin Gradual improvement is the rule in patients who survive the acute phase Other complications of diphtheria...
... cutaneous diphtheria is identified should have the nasopharynx cultured for C diphtheriae The laboratory media for cutaneous diphtheria are the same as those used for respiratory diphtheria: Löffler's ... respiratory diphtheria remains a notifiable disease in the United States, whereas cutaneous diphtheria is not Diphtheria: Treatment Diphtheria Antitoxin Prompt administration of diphtheria antitoxin ... critical in the management of respiratory diphtheria The antitoxin—a horse antiserum—is effective in reducing the extent of local disease as well as the risk of complications of myocarditis and neuropathy...
... diphtheria and tetanus toxoids and acellular pertussis vaccine, adsorbed) is the currently recommended vaccine for children up to the age of 7; DTaP replaced DTP (diphtheria and tetanus toxoids and ... diphtheriae in the community should be treated and vaccinated when identified Nondiphtherial Corynebacteria and Related Species Nondiphtherial corynebacteria, which are also referred to as diphtheroids ... tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine formulated for adolescents and adults Tdap was licensed for use in the United States in 2005 and is the recommended booster...
... formed of the inner circular and outer longitudinal muscle layers The vasa recta, which supply the mucosa and submucosa of the colon, penetrate the circular muscle The weakness of the vascular ... preparation The bleeding was controlled by #3-0 Vycryl intracorporeal suture, andthe invagination of the diverticulum was performed laparoscopically The recovery was uneventful, andthe patient ... Invagination and diverticulectomy have been performed to treat diverticula to preserve the blood supply to the intestine In the present case, blood supply to the intestine had to be preserved because the...
... Vietnamese and English and then analyzing noun phrases from the two selected chapters of “Pride and Prejudice” by Jane Austen and their equivalents in the translated version The results of the study ... general from the source language text into the mother tongue and vice versa This is also the case when the author read the favourite novel “Pride and Prejudice” by Jane Austen Then in the author’s ... dependent of the personal or non-personal character of the antecedent, the function of the pronoun and also their position in the relative clause are frequently used and enclosed by a comma These clauses...
... on average over the 1990s (this is not the case in Ireland andthe Netherlands for the former, and Finland for the latter) The picture is less clear in the case of mortgages and long-term loans ... Germany andthe Netherlands For the latter, it goes up in Spain, Ireland, Italy, down in Belgium and Germany However, it could be the case that the term CC captures a trend in the level of the bank ... can be explained bythe change in the underlying trend in the market rate that coincided with the beginning of EMU We then test whether the EMU break is due to the change in the volatility of...
... toxicity to infected cells There is an inverse relationship between toxicity and virulence—i.e., the more cytotoxic the strain, the less virulent it is in animals Once in the cytosol, L monocytogenes ... LLO probably acts by inserting itself into an acidifying phagosome, thereby preventing the vesicle's maturation In addition, LLO acts as a translocation pore for one or both of the L monocytogenes ... synthesis and activity are controlled at multiple levels to ensure that its lytic activity is limited to acidic vacuoles and does not affect the cytosol Mutations in LLO that influence its synthesis,...
... role The critical effector cells are cytotoxic (CD8+) T cells that recognize and lyse infected cells The bacteria grow and spread from cell to cell The host recognizes and lyses infected cells, and ... involving the generation of appropriate cytokines andthe compartmentalization of bacterial proteins for antigen processing and presentation Epidemiology L monocytogenes usually enters the body via the ... listeriosis seems to be prevented by trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis targeting other AIDSrelated infectionsThe diagnosis is typically made by culture of blood, cerebrospinal...
... for the diagnosis of these infections Other Focal Infections Focal infections of visceral organs; the eye; the pleural, peritoneal and pericardial spaces; andthe bones and joints have all been ... of fever and headache followed by asymmetric cranial nerve deficits, cerebellar signs, and hemiparetic and hemisensory deficits Respiratory failure can occur The subacute course andthe often ... instances, occur in the cerebellum andthe spinal cord Invasion of the brainstem results in a characteristic severe rhombencephalitis, usually in otherwise healthy older adults The presentation...
... Austria Authors’ contributions WJS and RWL conceived of and designed the study WJS and PR analyzed and interpreted the data WJS drafted the article and, along with ET and SJW, critically revised it ... accordance with the Declaration of Helsinki andthe recommendations of the local ethics committee Discussion The umbilical vein is obliterated a few days after birth and is usually not part of the actual ... Page of and RWL approved the final article WJS, RK and RWL provided administrative, technical, or logistic support WJS collected and assembled the data All authors have read and approved the final...
... Austria Authors’ contributions WJS and RWL conceived of and designed the study WJS and PR analyzed and interpreted the data WJS drafted the article and, along with ET and SJW, critically revised it ... accordance with the Declaration of Helsinki andthe recommendations of the local ethics committee Discussion The umbilical vein is obliterated a few days after birth and is usually not part of the actual ... Page of and RWL approved the final article WJS, RK and RWL provided administrative, technical, or logistic support WJS collected and assembled the data All authors have read and approved the final...
... located nearby in the RuvA sequences from M pneumoniae, M genitalium, and U urealyticum and Holliday junction bound by EcRuvA (Table 1), illustrating the additional stability of the Holliday ... resolvasome complex requires the binding of RuvA to one face of the junction and RuvC to the other [8,9] Complexes formed bythe loading of both RuvA and RuvC on a synthetic junction can be detected ... reflected in the high conservation of the sequences forming the pin in the majority of bacteria with the exception of two Mycoplasma species and one of Ureaplasma In the RuvA proteins from these organisms...
... presented in the thesis and give some suggestions for further studies The References and Appendix are provided at the end of the thesis PART II: DEVELOPMENT CHAPTER 1: THEORETICAL BACKGROUND 1.1 The Nature ... study on ambiguity causedby ellipsis and substitution In this thesis, the author discusses different definitions of ambiguity, ellipsis and substitution and their types first Then, the survey is ... (N), Epithet (E), Classifier(C), and Quantifier (Q) The Deictic is normally a determiner, the Numerative a numeral or other quantifier, the Epithet is an adjective andthe Classifier a noun, the...
... introduced bythe primer is underlined) and CD14 (5¢-AAGCTTAGTTAGATATCAGAGACC ATG) The PCR product was digested with NdeI and BamHI and cloned into pET3c cut with the same enzymes The wild-type and ... SacII and BamHI and cloned into pGP172 linearized with the same enzymes The resulting plasmids were pGP611 and pGP612 for the wild-type and F200W forms of hprK, respectively Mutagenesis of the ... 7.5, and mM dithiothreitol After 30 incubation at 25 °C, the fluorescence of the sample was recorded from 300 to 450 nm (a) Then 50 lM ATP/MgCl2 was added to the mixture andthe fluorescence of the...
... P. cactorum, and to verify the effect of water stress on the stem lesion development causedby P cactorum The article deals with the outcomes of these first infection experiments MATERIAL AND METHODS ... moderately pathogenic The length of lesions causedby P cactorum was statistically different from those causedby P gonapodyides and P. cambivora isolates on one hand and from the most aggressive ... and horse chestnut The identity of the isolates was verified by morphological analysis as well as bythe analysis of the ITS regions (Cerny et al 2009) P. cactorum isolates are deposited in the...
... AS, FZ, and MM participated in the design of the manuscript and they revised and critically reviewed the manuscript All authors read and approved the final manuscript Competing interests The authors ... be found near the edge of the leaflets along the line of closure; both on the atrial and ventricular sides of the leaflets They can even be found on the chordae andthe endocardium In this case ... Netherlands Department of Pathology, University Medical Center Groningen, the Netherlands Authors’ contributions WB collected the data, systematically reviewed the literature, and wrote the manuscript...
... evidenced bythe fact that both hemolysis and pancytopenia as well as the hyperhomocysteinemia were all corrected by cobalamin treatments It is also evident that all the three cases reported here either ... 12 13 The authors declare that they have no competing interests Authors' contributions The case report was initially originated by UA, JTG, and WC Later, two more cases were added by WH and PV ... efforts UA, WH and CTH particularly contributed to the literature update and search All authors participated in drafting and editing the manuscript All authors read and approved the final manuscript...