infection—the role of cd62himemory cd8 t tcm cells
The role of CD8 t cells in the differentiation of TNF iNOS producing dendritic cells and TH1 responses
Ngày tải lên :
09/09/2015, 18:58
... uninfected cells in a bystander manner (Mitrovic et al., 1994) 1.7.2 Bystander activation of T- cells Bystander activation of T cells, i.e the stimulation of unrelated, heterologous T- cells by cytokines ... supported by studies demonstrating the involvement of CD8 T cells in the generation of protective CD4 Th1 responses during retroviral infection (Peterson et al., 2002) Importantly, CD8 T cells ... depletion of CD8 T cells abrogated the protective Th1 response induced by DNA vaccination (Gurunathan et al., 2000), suggesting that CD8 T cells were vital for the polarization of Th1 cells This was...
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The role of interferon gamma in regulating antigen specific CD8 t cell responses in a mouse model of influenza
Ngày tải lên :
10/09/2015, 09:25
... HA is a lectin that mediates the binding of the virus to target cells and facilitates the entry of the virus into the target cell The proteolytic cleavage of the HA molecule (HA0) into HA1 and ... and the factors that regulate memory T cell responses are important for generation of efficient vaccines The factors that regulate the contraction of the CD8+ T cell response and the magnitude of ... clearance, the quantity of virus-specific cells generated is equally important in determining the outcome of infection Tetramer staining of CD8+ T cells reveals that there is a strong correlation between...
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Báo cáo y học: "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models" pps
Ngày tải lên :
09/08/2014, 06:22
... considered an important target for the treatment of destructive arthritis The discovery of IL-17 family members may further extend the role of this cytokine family in arthritis pathology IL-17F showed ... whether or not a patient will respond to anti-TNF and anti-IL-1 therapy AntiIL-17 cytokine therapy might be an interesting new antirheumatic approach that could contribute to the prevention of ... IL-17-deficient mice phenotypically [27,28] These studies indicate the existence of an IL-23/IL-17 axis of communication between the innate and adaptive parts of the immune system that might be an interesting...
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Báo cáo y học: "The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells" doc
Ngày tải lên :
09/08/2014, 06:22
... treated with control IgG These data imply that a substantial proportion of the T- cell compartment is still activated 14 days after intra-articular antigen challenge in the absence of Treg cells ... at the site of inflammation is also an important part of the activity of Treg cells In this regard, data on the curative effects of Treg cells in experimental disease models are conflicting To ... clearly demonstrates that their suppressive effect is not strictly limited to autoreactive T cells Taking into consideration that Treg cells are also critically involved in the control of immune responses...
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Báo cáo khoa hoc:"Heritability of susceptibility to Salmonella enteritidis infection in fowls and test of the role of the chromosome carrying the NRAMP1 gene" ppt
Ngày tải lên :
09/08/2014, 18:21
... intravenous inoculation is more repeatable The goal of this work was to estimate the heritability of resistance for fowls inoculated intravenously at 13 weeks of age, and to test the effect of ... the total number of bacteria than on concentration (number of CFU per gram of organ), only the results on the former traits are shown 3.2 Estimated heritabilities of the presence of S enteritidis ... suggests that most of the genes controlling contamination of these two organs are the same A positive but slightly smaller genetic correlation was also observed between the numbers of S enteritidis...
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Báo cáo y học: "The role of F1 ATP synthase beta subunit in WSSV infection in the shrimp, Litopenaeus vannamei" potx
Ngày tải lên :
12/08/2014, 04:20
... 5’-CTG AGG TAC CGG ATC CCG TGT CGC CCT GAC TGG T- 3’ Primer 5’-CTG AGG TAC CGG ATC CCA ACA TTT TCC GCT TCA CA-3’ Primer 5’-CTG AGG TAC CGG ATC CCC CTG ACT GGT CTG ACT GTG G-3’ Primer 5’-CTG AGG TAC ... conducted We investigated the interaction of F1-ATP synthase beta subunit with WSSV, and for the first time describe the role of F1-ATP synthase beta subunit during WSSV infection Results A 53 ... invertebrate prokineticin, astakine, and it is located on the plasma membrane of crayfish Hpt cells [26].It will be interesting to further investigate the precise role of F -ATP synthase beta subunit...
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Báo cáo khoa học: " The role of NH4Cl and cysteine proteases in Human Papillomavirus type 16 infection" ppsx
Ngày tải lên :
12/08/2014, 04:21
... 1-tail T test) These data suggested that cathepsin B but not cathepsin L treatment of HPV16 reporter-virions can overcome furin inhibition HPV16 Infectivity is blocked in the absence of cathepsin ... hour These data suggest that protease treatment of HPV16 for hour can increase binding, that longer time incubation results in a loss of total binding, and that the increase in infection after ... 6:109 vent the acidification of vesicles, unfortunately this treatment also results in the loss of fusion of intracellular vesicles In fact, it was shown that NH4Cl prevented the movement of JC...
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Báo cáo y học: " The role of vitamin D in pulmonary disease: COPD, asthma, infection, and cancer" ppsx
Ngày tải lên :
12/08/2014, 13:22
... RW: The effect of additions of fluorine to the diet of the rat on the quality of the teeth 1925 Studies on experimental rickets XXI An experimental demonstration of the existence of a vitamin ... again at and months after start of treatment Reduction in TBscore and sputum smear conversion rates did not differ among VitD and placebo treated patients Taken those data together there seems to ... benefit of VitD in the treatment of tuberculosis but this could not be reproduced in the largest study so far Respiratory tract infections (RTI) RTI are more common in the winter period than during...
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Báo cáo y học: " The role of γδ T cells in airway epithelial injury and bronchial responsiveness after chlorine gas exposure in mice" pps
Ngày tải lên :
12/08/2014, 15:20
... reagent to reduce non-specific binding The tissues were then treated with anti-PCNA antibody or isotype control antibody (negative control) for 30 minutes at 37°C, rinsed with TBS and treated with ... secondary to neutrophil activation could contribute to the extent of shedding [15] The latter mechanism seems less likely since the inflammatory response to epithelial damage was also attenuated in the ... response compared to wild type mice The lack of γδ T cells was associated with an abrogation of the changes in responsiveness to methacholine, suggesting that the intensity of the inflammatory response...
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Báo cáo y học: "The role of unintegrated DNA in HIV infection" docx
Ngày tải lên :
13/08/2014, 01:21
... Even with successful entry and reverse transcription, there is a rate of attrition associated with attempts to integrate virus into host chromatin that is mediated by host factors [61,62] Of the ... from integrating The authors of these studies also demonstrated that entry receptor downregulation contributed to restriction of superinfection prior to integration, as additional superinfection ... with host factors that are not necessarily captured in transfection studies These results also imply that there is active control of transcription from unintegrated DNA and it will be interesting...
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Báo cáo y học: " The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells" potx
Ngày tải lên :
13/08/2014, 13:20
... and 9) It is important to note that wildtype p21/waf1 has two cyclin binding motifs, one at the N- and the other at the C- terminus [20] p21/waf1 (mut) is mutated at the N-terminus and is therefore ... "knockin", demonstrating that cyclin E is a major downstream target of cyclin D1 [64] This also shows that activation of cyclin E is pertinent to transition from G1 to the S phase The role of cyclin ... independently of p53 [17,18] In fact, in HTLV-1 infected cells, it has previously been shown that Tax transactivates p21/waf1 transcription independent of p53 and through E2A sites close to the TATA...
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Báo cáo y học: " The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children" doc
Ngày tải lên :
13/08/2014, 20:22
... intrathecal concentrations and mortality Inpatient mortality is high in children admitted with pneumonia and bacterial meningitis in Malawi; therefore, it is important to determine the utility of ... of these angiogenic factors as biomarkers for the identification of patients at risk of a poor outcome Our data are in keeping with current evidence that suggests that the growth factors together ... regarding other study populations may be difficult to make Nonetheless, we believe that the high mortality in our patients represents the most severe end of the spectrum (that is, MODS without intensive...
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A STUDY ON THE ROLE OF USING VIETNAMESE IN TEACHING ENGLISH VOCABULARY TO THE 10TH FORM ETHNIC MINORITY STUDENTS AT VUNG CAO VIET BAC HIGH SCHOOL -Nghiên cứu về vai trò của việc sử dụng Tiếng Việt trong dạy từ vựng Tiếng Anh cho học sinh dân
Ngày tải lên :
30/03/2015, 14:00
... pay the most attention to when you introduce new words to your students? This question was asked to investigate the aspects of vocabulary that teachers often pay the most attention to when they ... the other hands, no teacher paid the most attention to word – form In short, from teachers‟ viewpoints about the aspect of word they paid the most attention to, the author can conclude that they ... skill of using contextual clues It might encourage them to wait for the teacher to translate instead of attempting to work out meaning of the words by themselves They all agreed the view that teacher...
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The role of ORF3 protein in the molecular pathogenesis of porcine circovirus 2 infection
Ngày tải lên :
10/09/2015, 08:38
... R-PCVPST (5-TGCACTGCAGTATTCTTTATTCTGCTG-3) and inserted into pBlueScript SK vector and cloned in DH5α E Coli At least 15 clones of each of the mutant genome were sequenced on both strands using the ... delineated into three parts; the first part comprises the characterization of the role of PCV2 ORF3 in the infection of its natural host, the piglets (Karuppannan et al., 2009) This study was essential ... death in the wildtype virus The mutant 52 and mutant 85 still induced 80% or more cell death in infected cells The mutations in the ATG mutant and mutant 27, independent of each other in preventing...
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The role of host cell ether lipids in influenza virus infection
Ngày tải lên :
12/10/2015, 17:36
... alteration to the distribution of HA and hence affecting the maturation of virus particles (Hidari et al., 2006) It is postulated that GSLs may therefore contribute not just in the viral attachment ... Whittaker (2003) also reported that depleting the influenza virus lipid envelope of cholesterol, by treatment of methyl-ß-cyclodextrin (MßCD), impairs the infectivity of the virus particle This ... potential in targeting host cell factors for antiviral strategies The objective of this study was to understand the functional role of ether lipids in influenza virus life cycle, by implementing...
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The Role of Power
Ngày tải lên :
22/08/2012, 22:07
... Gain disclosure of something private or personal about your counterpart • Expression of trust Identify true motivations and sources of objections Be patient and use probing questions Attempt to satisfy some need ... Develop extensive command of negotiation strategies or a repertoire of strategies and tactics Don t utilize the same tactic/strategy more than once – might be perceived as predictable and less skilled ... Food, room, lighting, temperature, seating, etc Create the ambience or atmosphere that is most conducive for each particular negotiation instance Rule #10: Threat is a Last Resort Negotiators who use cooperative strategies have ...
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Circuit theory of finance and the role of incentives in financial sector reform
Ngày tải lên :
24/10/2012, 09:33
... competition to be consistent with stability: incentives should be used to attract to the market the range and types of institutions apt to fill the whole spectrum of (sectoral and maturity) segments ... information A critical component for the smooth functioning and integrity of the circuit is the improvement of the quality and quantity of available information To the extent that financial institutions ... externalities to the extent that dishonest and imprudent action from one market participant may damage the reputational capital of others, and that sound financial infrastructures that strengthen...
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Facts of Vietnam Freight forwarding industry and the role of Vietnam Freight Forwarders Association (VIFFAS) to the industry in international economic integration processhelpful to Oristar.doc
Ngày tải lên :
27/10/2012, 16:42
... Committee of Khanh Hoa province The participation of the private sector in port management in Vietnam is still very limited There are only two ports with private sector participation so far It is the ... import-export goods freight forwarding activities of the S.R of Vietnam, and on this basis to integrate with such professional colleagues on the world The Association has the role of coordinating the activities ... Loan stressed that Vietnam freight forwarding had seen a rapid development in quality, which has improved its status and contributed to Vietnam's transportation activities This is thanks to the...
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Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"
Ngày tải lên :
03/11/2012, 11:06
... Int J Med Sci 2009, 134 aged This is particularly true with regards to T gondii, where the consequences of infection can be very severe, while the risk of living with one’s beloved cat is practically ... Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated with seropositivity of pregnant women in Korea J Parasitol 2008; ... Juranek DD et al Caring for pets of immunocompromised persons Can Vet J 1995; 36: 217-222 Glaser CA, Angulo FJ, Rooney JA Animal-associated opportunistic infections among persons infected with the human...
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