induction chemotherapy in head and neck cancers

... symptoms suggestive of head and neck cancer 3.2 diagnosis and staging Diagnosis and staging of head and neck malignancy will normally include clinical examination by an experienced clinician, fibre ... including dental and medical practitioners, should be aware of the presenting features of head and neck cancer, and the local referral pathways for suspected cancers screening for head and neck ... support the use of chemotherapy alone as a curative treatment for squamous carcinoma of head and neck In patients with head and neck cancer the administration of chemotherapy in combination with locoregional...

Ngày tải lên: 14/02/2014, 22:20

... Guide to NECK DISSECTION CLASSIFICATION AND TNM STAGING OF HEAD AND NECK CANCER Committee for Head and Neck Surgery and Oncology American Academy of Otolaryngology– Head and Neck Surgery Neck Dissection ... guide to neck dissection classification and TNM staging of head and neck cancer / Committee for Neck Dissection Classification, American Head and Neck Society [and] Committee for Head and Neck Surgery ... Congress Cataloging -in- Publication Data Pocket guide to neck dissection classification and TNM staging of head and neck cancer — 3rd ed / Committee for Head and Neck Surgery and Oncology, American...

Ngày tải lên: 15/03/2014, 00:20

... ALL HEAD AND NECK CANCERS REDUCING RISK The risk of having head and neck cancer can be reduced by: B B not smoking or chewing tobacco C increasing the intake of fruit and vegetables ... and fish oils C reducing the intake of red meat, fried food and fat limiting alcohol consumption, in line with government guidelines PRESENTATION AND SCREENING All healthcare practitioners, including ... THE HEAD AND NECK Oral cavity Oropharynx Larynx Hypopharynx ALL HEAD AND NECK CANCERS DIAGRAM OF THE LYMPH NODES LEVELS IN THE NECK I II III VI IV V NECK DISSECTION TECHNIQUES Comprehensive neck...

Ngày tải lên: 15/03/2014, 01:20

... from head and neck cancers, are discussed in Improving Outcomes in Haematological Cancers. 4 There are marked regional variations in the incidence of head and neck cancers, with rates ranging from ... NHS National Institute for Clinical Excellence Guidance on Cancer Services Improving Outcomes in Head and Neck Cancers The Manual Improving Outcomes in Head and Neck Cancers Cancer service ... connective and soft tissues, and various glands Skull base cancers are included among head and neck cancers, but tumours that originate in the skull are very rare; most cancers that invade the...

Ngày tải lên: 22/03/2014, 16:21

... objective response and cancer-specific survival in patients treated by Cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma Clin Cancer Res 2007, ... Papakostas P, et al: Induction chemotherapy with docetaxel and cisplatin followed by concomitant chemoradiotherapy in patients with inoperable non-nasopharyngeal carcinoma of the head and neck Anticancer ... predicts cisplatinbased chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area Journal of Translational Medicine 2011 9:31 ...

Ngày tải lên: 18/06/2014, 19:20

... objective response and cancer-specific survival in patients treated by Cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma Clin Cancer Res 2007, ... Papakostas P, et al: Induction chemotherapy with docetaxel and cisplatin followed by concomitant chemoradiotherapy in patients with inoperable non-nasopharyngeal carcinoma of the head and neck Anticancer ... predicts cisplatinbased chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area Journal of Translational Medicine 2011 9:31 ...

Ngày tải lên: 20/06/2014, 03:20

... continuous LDR irradiation, which, in turn, minimizes injury to the overlying skin and surrounding neurovascular structures In this study, we investigated the efficacy and feasibility of percutaneous ... history and physical condition of all the patients, hematological and chemical tests, and obtained CT images of the head and neck and radiographs of the chest Patient characteristics are shown in ... head and neck cancer with curative intent Int J Radiat Oncol Biol Phys 1994, 29:687-698 Emami B, Marks JE: Re-irradiation of recurrent carcinoma of the head and neck by afterloading interstitial...

Ngày tải lên: 09/08/2014, 09:20

... reirradiation combined with chemotherapy after salvage surgery in head and neck carcinoma Curr Opin Oncol 2001, 91:2071-6 Temam S, Pape E, Janot F, Wibault P, Julieron M, Lusinchi A, Mamelle G, Marandas ... were similar (66% in SRS and 61% in SRT), severe side effects occurred at a rate of 33% for SRS (brain necrosis, 16%; bleeding, 5%), and 21% for SRT (brain necrosis, 12%; bleeding, 2%) Other lesions ... also invaded and damaged it Furthermore, when the artery has been weakened and affected by infection and necrosis, copious bleeding easily occurs Bleeding may also be caused by due to the following:...

Ngày tải lên: 09/08/2014, 09:21

... delineation using PET in head and neck cancers: threshold contouring and lesion volumes Med Phys 2006, 33:4280-4288 Black QC, Grills IS, Kestin LL, Wong CO, Wong JW, Martinez AA, Yan D: Defining ... patients with primary head and neck carcinoma were selected for radiotherapy after discussion in multidisciplinary conference and obtaining informed consent following the rules of our institution Patients ... Dawson L, Keller A, Kim J, Ringash J, Yu E, Hendler A, Waldron J: Intraobserver and interobserver variability in GTV delineation on FDG-PET-CT images of head and neck cancers Int J Radiat Oncol Biol...

Ngày tải lên: 09/08/2014, 09:22

... Kowalski LP: Interstitial high-dose-rate brachytherapy combined with cervical dissection on head and neck cancer Head Neck 2005, 27(12):1035-41 Mazeron JJ, Noel G, Simon JM: Head and neck brachytherapy ... LRFS and OS at and years was margin status, p = 0.0007 and p = 0.0002, respectively Figure Doses at skin were measured and where in the range of 32–60% Four patients (19.4%) experienced acute and ... concomitant chemotherapy and radiotherapy regimen for squamous cell head and neck cancer: a systematic review of the published literature with subgroup analysis Head Neck 2001, 23:579-589 Hinerman...

Ngày tải lên: 09/08/2014, 10:21

... the increasing incidence of head and neck cancers in women consequent to an increasing exposure to risk factors [40,41], while the decrease in lymphomas may actually reflect the decreasing incidence ... lineages in the head and neck whereas neuroendocrine tumours of the head and neck are rare It is expedient to conduct this sort of study periodically to monitor the changing trends of head and ... and JO were involved in the conception and design of the study AO acquired the data AO and BF participated in the analysis and interpretation of the data BF, EEU and B were involved in drafting...

Ngày tải lên: 11/08/2014, 20:21

... inhibitor-kappaB kinase (IKK)α/β/γ and casein kinase complexes modulating NFκB1, RELA and cREL, and alternative pathways involving NF-κB inducing kinase and IKKα modulating NFκB2 and RELB [1,2,11,24-26] ... colony-stimulating-factor; HNSCC, head and neck squamous cell carcinoma; IGF, insulin-like growth factor; IκB, inhibitor kappaB; IKK, inhibitor-kappaB kinase; IL, interleukin; IL-R, interleukin receptor; ... sensitivity in head and neck squamous cell carcinoma lines Head Neck 2003, 25(8):654-661 Ongkeko WM, Altuna X, Weisman RA, Wang-Rodriguez J: Expression of protein tyrosine kinases in head and neck squamous...

Ngày tải lên: 14/08/2014, 08:20

... against infection and invading connective tissue There are still very few studies applying the methods of tissue engineering to produce tracheal replacements and to examine these in vitro and in ... this technique and bearing in mind the contraindications, more than 90% of the children can nowadays be extubated without problems In spite of the progress, in children undergoing single-step surgical ... intubation over several days as an intratracheal splinting An external splinting by metallic microplates in the surgical tracheal reconstruction was described first time by Zalzal and Deutch in...

Ngày tải lên: 25/10/2013, 08:20

... gradually increase in size and number and form sinuses that open onto the face and neck Although infection is often seen in the jaw area, Actinomyces infections have been described in other sites, including ... and immunostains can be used to identify the organism in smears and tissue sections.94 A C Fungal Diseases A variety of fungal infections can result in head and neck manifestations Head and neck ... but untreated ocular involvement can lead to scarring and pain in infected children HIV Infection with HIV (an RNA Lentivirus) can manifest in several ways in the head and neck area Many of these...

Ngày tải lên: 19/02/2014, 08:20

... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non-specific staining, the section was incubated with protein block (DakoCytomation) ... membranous staining and Her3 (b, membranous and cytoplasmic staining, and c, predominant cytoplasmic staining) 400 × magnification Takikita et al Journal of Translational Medicine 2011, 9:126...

Ngày tải lên: 18/06/2014, 22:20

... strong (3+), and 26% showed no TLR4 staining (Figure 1; Table 3) TLR4 staining (all scores) showed a diffuse and fine granular cytoplasmatic pattern Distinct membrane staining was observed in some ... well as overcoming the immune defect induced by deficient TLR4 signaling by combining chemotherapy with alternate TLR4 agonists Abbreviations (HNSCC): Head and neck squamous cell carcinomas; (TLR): ... CW and GL participated in collection and assembly of data CP and AS participated in data analysis and interpretation CB, HSB, AB and AS wrote the manuscript All authors read and approved the final...

Ngày tải lên: 18/06/2014, 22:20

... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non-specific staining, the section was incubated with protein block (DakoCytomation) ... membranous staining and Her3 (b, membranous and cytoplasmic staining, and c, predominant cytoplasmic staining) 400 × magnification Takikita et al Journal of Translational Medicine 2011, 9:126...

Ngày tải lên: 20/06/2014, 04:20

... strong (3+), and 26% showed no TLR4 staining (Figure 1; Table 3) TLR4 staining (all scores) showed a diffuse and fine granular cytoplasmatic pattern Distinct membrane staining was observed in some ... well as overcoming the immune defect induced by deficient TLR4 signaling by combining chemotherapy with alternate TLR4 agonists Abbreviations (HNSCC): Head and neck squamous cell carcinomas; (TLR): ... CW and GL participated in collection and assembly of data CP and AS participated in data analysis and interpretation CB, HSB, AB and AS wrote the manuscript All authors read and approved the final...

Ngày tải lên: 20/06/2014, 04:20