incidence classification and outcomes of acute kidney injury pdf

... Incidence and outcomes in acute kidney injury: a comprehensive population-based study J Am Soc Nephrol 2007, 18:1292-1298 Ricci Z, Cruz D, Ronco C: The RIFLE criteria and mortality in acute kidney ... determination of AKI severity in critically-ill patients Page of Abbreviations AKI: acute kidney injury; AKIN: Acute Kidney Injury Network; CKD: chronic kidney disease; GFR: glomerular filtration rate; IQR: ... risk of in-hospital death [25] Additionally, several studies have now shown that the change in severity stage of AKI (acute kidney injury network (AKIN) or risk, injury, failure, loss of kidney...

Ngày tải lên: 13/08/2014, 20:22

... Bidwell, Professor of Anatomy & Cell Biology; Dr Randy R Brutkiewicz, Professor of Microbiology & Immunology and Associate Dean for Graduate Studies, Dr Jonathan D Tune, Associate Professor of Cellular ... similarly capable of blunting the extent of injury Altogether, these results indicate the development of novel and exciting platform for the future study and management of renal injury Simon J Atkinson, ... TABLE OF CONTENTS List of Tables xvi List of Figures xvii I Introduction A Acute kidney injury 1 The growing prevelance of renal injury...

Ngày tải lên: 24/08/2014, 12:58

... repositories Process outcomes Measures of effectiveness of current processes for changing behavior/attitude of caregivers and ultimately patient outcomes from AKI AKI, acute kidney injury; CRRT, continuous ... clinical presentation and following adequate fluid resuscitation when applicable Note: Many acute kidney diseases exist, and some (but not all) of them may result in acute kidney injury (AKI) Because ... standards for definition and classification of AKI Definition and diagnostic criteria of AKI For any condition, the clinician needs to know whether the disease is present and, if so, where and...

Ngày tải lên: 13/08/2014, 03:20

... known risk factor for AKI, Table Baseline characteristics of patients with and without acute kidney injury No acute kidney injury Acute kidney injury P value Number 21 18 Age (years)* 2.1 ± ± 5.2 ... IL-6 levels and acute kidney injury was detected (P = 0.06) An interaction was not detected between IL-8 levels and acute kidney injury (P = 0.83) We therefore stratified the analysis of IL-6 levels ... hypothesized that IL-6 and IL-8 would be early biomarkers of acute kidney injury In animals, we and others demonstrated that AKI causes lung injury, characterized by neutrophil infiltration and increased...

Ngày tải lên: 13/08/2014, 16:21

... the ICU: risk factors and outcome evaluated by the SOFA score Intensive Care Med 2000, 26:915-921 Kellum JA, Bellomo R, Ronco C: Definition and classification of acute kidney injury Nephron Clin ... Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A: Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Crit Care 2007, 11:R31 Available online http://ccforum.com/content/13/5/R171 ... conception and design, and drafted the manuscript WYL, DMH, SLL and PRT were involved in acquisition and interpretation of data YFL, GHY, and CHW participated in the sequence alignment and drafted...

Ngày tải lên: 13/08/2014, 19:20

... A: Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Crit Care 2007, 11:R31 Pickering JW, Frampton CM, Endre ZH: Evaluation of trial outcomes in acute ... study and the concept of measuring uCysC and participated in the study design, interpretation of results, and revision of the draft Acknowledgements We thank the staff of the ICUs of Dunedin and ... are the standard errors of the mean Figure Median urinary cystatin C differences (a) Patients with and without acute kidney injury (AKI) and with and without sepsis on admission to ICU; and (b)...

Ngày tải lên: 13/08/2014, 20:22

... Ronco C, Warnock DG, Levin A, the Acute Kidney Injury Network: Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Crit Care 2007, 11:R31 Ricci Z, Ronco ... heterogeneous and AKI etiology and timing are often unclear Furthermore, the prevalence of sepsis in the intensive care unit (ICU) may limit the use of uNGAL as a specific biomarker of kidney injury ... initiation of ventilation and that urine was collected once per day for up to days if possible (b) Acute kidney injury (AKI) urine specimens collected before AKI development were used for assessment of...

Ngày tải lên: 13/08/2014, 08:20

... serum and urine IL-6 • Urine IL-6 may be a useful early biomarker to detect acute kidney injury from acute tubular necrosis Abbreviations AKI: acute kidney injury; ALI: acute lung injury; ATN: acute ... the outcome of acute kidney injury (the EARLYARF trial) Kidney Int 2010, 77:1020-1030 26 Dennen P, Douglas IS, Anderson R: Acute kidney injury in the intensive care unit: an update and primer ... 0.000 0.000 000 0.000 Figure Clinical utility of urine IL-6 to diagnose early acute kidney injury (A) A urine IL-6 of ≥75 pg/mg predicts acute kidney injury with 88% sensitivity (B) Receiver operating...

Ngày tải lên: 13/08/2014, 21:21

... traumatic brain injury, CT is a vital tool for the assessment and remains the investigation of choice even following the advent of MRI, due both to the ease of monitoring of injured patients and the ... appearance and a more irregular inner margin An ICH occurs due to stretching and shearing injury, often due to impaction of the brain against the skull on the side opposite to the injury Thus ... boundary of a lobular region LFS is a grouping of a specific region of the lung, usually a lobe 40 Figure 2.8: The lobular feature set (LFS) of ASSERT or a combination of adjacent lobes, and the...

Ngày tải lên: 10/09/2015, 08:42

... Campbell DJ: A phase trial of nebulised heparin in acute lung injury Crit Care 2008, 12:R64 Geiser M, Schürch S, Gehr P: Influence of surface chemistry and topography of particles on their immersion ... in acute lung injury /acute respiratory distress syndrome Curr Opin Crit Care 2008, 14:11-15 Hofstra JJH, Juffermans NP, Schultz MJ, Zweers MM: Pulmonary coagulopathy as a new target in lung injury ... The acute respiratory distress syndrome N Engl J Med 2000, 342:1334-1349 Schultz MJ, Millo J, Levi M, Hack CE, Weverling GJ, Garrard CS, Poll T: Local activation of coagulation and inhibition of...

Ngày tải lên: 13/08/2014, 11:22

... kidney injury and incidence from the Australia New Zealand Intensive Care Society Adult Patient Database, 1996–2005 acute kidney injury and incidence from the Australia New Zealand Intensive ... for coma Clinical outcomes Outcomes extracted from the APD included an incidence of early AKI at or within 24 hours of ICU admission (as a proportion of all ICU admissions) and the hospital mortality ... the incidence of AKI for patients with no comorbid illness (annual percentage change, 2.9%; 95% CI, -0.4 to 6.2; P = 0.08) There were no significant Figure Summary of cases of acute kidney injury...

Ngày tải lên: 13/08/2014, 03:21

... culprit in both his acute kidney injury and pancreatitis Conclusion AAS use and misuse is being seen in an expanding population of patients because they are readily available and often perceived ... clinical jaundice [7] In this paper, we present a case of pancreatitis, cholestasis of the liver and acute kidney injury associated with the use of methandrostenolone for aesthetic purposes in a 50-year-old, ... Rosenfeld et al.: Cholestatic jaundice, acute kidney injury and acute pancreatitis secondary to the recreational use of methandrostenolone: a case report Journal of Medical Case Reports 2011 5:138...

Ngày tải lên: 11/08/2014, 00:23

... completely and stopped entirely, following months of treatment At 8-month follow-up, the patient's creatinine was 0.8 mg/dl and there was no proteinuria Discussion Oliguric acute kidney injury occurs ... changes in hematocrit (A) and creatinine levels (B) of the patient Therapy scheme and resultant changes in hematocrit (A) and creatinine levels (B) of the patient Hemodialysis and erythropoietin treatments ... Vijayan A: Use of EPO in critically ill patients with acute renal failure requiring renal replacement therapy Am J Kidney Dis 2005, 46(5):791-798 Abbreviations ARF: acute kidney injury; MCD: minimal...

Ngày tải lên: 11/08/2014, 19:21

... fall of mortality of patients with acute renal failure: what the analysis of two databases does and does not tell us J Am Soc Nephrol 2006, 17:923-925 Dejavaran P: Emerging biomarkers of acute kidney ... Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A: Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Crit Care 2007, 11:R31 ... serum creatinine and urine output Emerging biomarkers of AKI, such as neutrophil gelatinase-associated lipocalcin and cystatin C, give us a view of the biological clock, and the use of commercially...

Ngày tải lên: 13/08/2014, 08:20

... recovery of renal function and adversely impact patient survival [30] Several studies over the past decade have evaluated the impact of timing of initiation of CRRT on outcomes of AKI In the first of ... acute kidney injury of the critically ill patient Nat Clin Pract Nephrol 2007, 3:118-119 22 Himmelfarb J: Continuous dialysis is not superior to intermittent dialysis in acute kidney injury of ... DW: Acute kidney injury, mortality, length of stay, and costs in hospitalized patients J Am Soc Nephrol 2005, 16:3365-3370 Liano F, Junco E, Pascual J, Madero R, Verde E: The spectrum of acute...

Ngày tải lên: 13/08/2014, 08:20

... Beginning and Ending Supportive Therapy for the Kidney (B.E.S.T Kidney) Investigators Writing Committee Patient and kidney survival by dialysis modality in critically ill patients with acute kidney injury ... conception and design, patient enrollment, acquisition of data, analysis and interpretation of data, and critical revision of the manuscript DNC participated in patient enrollment, acquisition of data, ... analysis and interpretation of data, drafting and critical revision of the manuscript RF, DKM, GM, AM, FM, MF, MM, RR and SL participated in conception and design, patient enrollment, acquisition of...

Ngày tải lên: 13/08/2014, 16:20

... Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators: Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute kidney injury ... Acute Kidney Injury Network (AKIN): report of an initiative to improve outcomes in acute kidney injury Critical Care 2007, 11:R31 Knaus WA, Draper EA, Wagner DP, Zimmermann JE: Prognosis in acute ... (range) Mean (SD) Mechanical ventilation Mortality * excluding acute kidney injury AKI = acute kidney injury; APACHE = acute physiology and chronic health evaluation score; Hb = haemoglobin; ICU...

Ngày tải lên: 13/08/2014, 19:20

... damage the kidney A meta-analysis of randomized controlled trials was performed to test this hypothesis Hyperoncotic albumin decreased the odds of acute kidney injury by 76% and of death by ... Hyperoncotic colloids and acute kidney injury: a meta-analysis of randomized trials Critical Care 2010 14: R191 Submit your next manuscript to BioMed Central and take full advantage of: Convenient ... patient age and gender, fluid regimen, criteria for diagnosing AKI, and incidence of AKI and death on the basis of intent to treat Statistical analysis The pooled odds ratios (ORs) for AKI and mortality...

Ngày tải lên: 13/08/2014, 21:21

... Molitoris BA, Ronco C, Warnock DG, Levin A, Acute Kidney Injury Network: Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Crit Care 2007, 11: R31 Levey ... be addressed for accurate recognition and staging of AKI Abbreviations AKI: acute kidney injury; ADQI: Acute Dialysis Quality Initiative; AKIN: Acute Kidney Injury Network; AUC: areas under the ... P, Dragun D, Haase-Fielitz A: A Comparison of the RIFLE and Acute Kidney Injury Network classifications for cardiac surgery-associated acute kidney injury: A prospective cohort study J Thorac...

Ngày tải lên: 14/08/2014, 07:21

... Summary of search strategy Detailed summary of search terms and strategy used for systematic literature search Abbreviations AKI: acute kidney injury; AKIN: Acute Kidney Injury Network; APACHE II: Acute ... survivors of acute kidney injury requiring dialysis JAMA 2009, 302:1179-1185 48 Bagshaw SM, George C, Bellomo R: Changes in the incidence and outcome for early acute kidney injury in a cohort of Australian ... as randomised? Yes Yes Was the method used to randomise described and appropriate (table of random numbers, computer generated, and so on)? Yes No Was there a description of withdrawals and dropouts?...

Ngày tải lên: 14/08/2014, 07:21