in vitro area under the concentration × time curve for target effect
An Analysis of OTC Interest Rate Derivatives Transactions: Implications for Public Reporting docx
Ngày tải lên :
06/03/2014, 03:20
... models to test the significance of different tenor groupings at explaining the variance in trade sizes A further discussion of the regression tests involved in determining the effects of tenor ... and sterling trades, there was no meaningful increase in the offsetting ratio over longer time periods following the initial trade By contrast, in US dollar denominated swaps, offsetting trades ... tenor groupings is included within the grouping itself For example, the 0-1 month bucket includes transactions with tenors up to, and including one month 29 The adjusted R-squared for the 20 tenor...
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Báo cáo khoa học: Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii Implications for the disulfide metabolism of anaerobic hyperthermophiles doc
Ngày tải lên :
07/03/2014, 17:20
... the flavin isoalloxazine ring with the C4 position of the nicotina˚ mide ring located 3.49 A from N5 of the isoalloxazine ˚ ring The active site cysteine thiolate is 3.48 A from N5 on the si-side ... of 5.7 · 10)3 and 1.3 · 10)3 min)1 for glutathione and CoA, respectively in the thiol form, as there was < 5% detected in the disulfide form, as determined by the concentration of (thiol + disulfide)–(thiol) ... sense for the enzyme to stabilize the EH4 form, since the reduced flavin is reactive with O2 Other enzymes in the family, such as the NADH peroxidase or glutathione reductase, tend to stabilize the...
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VIETNAM’S EXCHANGE RATE POLICY AND IMPLICATIONS FOR ITS FOREIGN EXCHANGE MARKET, 1986-2009 doc
Ngày tải lên :
07/03/2014, 18:20
... increase in its market share, the interbank market segment continues to play a limited role in Vietnam, in distinct contrast with the case in other countries In the global forex market, the interbank ... useful bits of information or illuminating anecdotes To further supplement the available information, the authors conducted a survey of forex dealers working for commercial banks The targeted population ... comparing the size of each forex market to the relevant country’s international trade volume As indicate in Table 4, in 2007 forex market turnover in the UK was almost 150 times the size of the...
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báo cáo khoa học: " HIV seroprevalence among participants at a Supervised Injection Facility in Vancouver, Canada: implications for prevention, care and treatment" docx
Ngày tải lên :
11/08/2014, 18:20
... providing a written informed consent, completing an interviewer-administered questionnaire and supplying a blood sample for HIV and hepatitis C testing All SEOSI participants provide informed ... public drug use, requiring help with injecting, sharing other drug using equipment, or binge drug use In the logistic regression analysis shown in Table 2, HIV positive status was independently associated ... relationship with prior incarceration, however there are risk behaviors that occur during the time of incarceration and more efforts to reduce the harms to inmates are needed [19-21] There are a number...
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and but or as cohesive devices in english written discouse - a contrastive analysis with vietnamese equivalents and implications for teaching writing skill at utehy
Ngày tải lên :
02/03/2015, 14:25
... it (for instance, thus, in other words) They may contrast new information with old information, or put another side to the argument (or, on the other hand, however) They may relate new information ... coordination are termed as coordinating conjunctions And a coordinator is organized at the process of conjoining units which are equal status In other words, coordination involves the linking ... by showing the achievement of the objectives of the study and the effectiveness of the methods used Then the limitations of the study are given Some suggestions for further study are also included...
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A silver opportunity rising longevity and its implications for business
Ngày tải lên :
06/12/2015, 23:05
... within HR departments, as they adjust to changing demographics Those who most to plan and adapt accordingly will also reinforce their position in the ongoing war for talent 10 © The Economist Intelligence ... This in turn provides an opportunity for businesses to rethink how they make use of their older workers A new role for seniors One of the biggest workforce changes likely to be introduced in the ... models for a new workforce? O ne of the most striking implications of the ageing of the overall population will be in terms of the impact it has on firms’ workforces Take Germany, where 25% of the...
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Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx
Ngày tải lên :
15/02/2014, 01:20
... obtained from ppi spider starting from the proteins grouped as above (Tables S2 and S3) In both cases, bioinformatic analysis revealed that the NF-jB pathway could be involved in determining the ... quenching These aspects are particularly relevant for an understanding of the biochemical pathways involved in PD neurodegeneration Indeed, the triggers leading to the specific death of dopaminergic ... as well as the proteins altered during the process, are still not well understood Most likely, the main players in determining the sensitivity of dopaminergic neurons are altered dopamine homeostasis...
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Therapeutic effect of hydrogen sulfide in a parkinsons disease model
Ngày tải lên :
12/10/2015, 17:36
... the function of dopaminergic neurons in 6OHDA-injured SN and striatum 3.6 ACS84 reversed the declined dopamine level in the 6-OHDA-injured striatum We further examined the dopamine level in the ... down dopamine Therefore, the inhibition of MAO-B would increase the level of dopamine in the brain Two MAO-B inhibitors had been developed, namely selegiline and rasagiline Numerous clinical researches ... channels but involved uncoupling protein in mice administrated with MPTP [209], which was contradicting to the previous understanding of H2S functions Therefore, investigation to identify the exact...
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Tài liệu Báo cáo " English - A global language and its implications for students " ppt
Ngày tải lên :
12/02/2014, 20:20
... that country For a long time, Vietnam was under the conquer of China, Chinese was the official language in Vietnam, the way of thinking and the academic style in every fields as writing, laws, ... acquire for their own purposes With that knowledge, students can have their own, independent way to approach then deal the issues they have Critical, independent and open thinking, therefore, are ... Thanks to their broaden knowledge, students will then evaluate their ways of thinking and change or develop it in a suitable and better way The change in students’ thinking can be seen in their study...
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Tài liệu Báo cáo khoa học: Expression and secretion of interleukin-1b, tumour necrosis factor-a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem cells Implications for their paracrine roles ppt
Ngày tải lên :
18/02/2014, 04:20
... washes and incubation with the nuclear stain 4¢,6-diamidino-2-phenylindone for 20 min, the MSCs were washed in NaCl ⁄ Pi for 10 and mounted in gelvatol for microscopic imaging Protein extraction ... buffer for 30 Cell lysates were then centrifuged at 13 000 g for 10 at °C and their protein concentrations were determined by the BCA Protein Assay Lysate amounts allowing equal protein loading ... was detected at the 6-h time point, and this release was elevated at the 12-h time point Furthermore, IL-10 secretion was augmented by the presence of LPS at each time point IL-10 inhibits cardiac...
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Tài liệu Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes pdf
Ngày tải lên :
19/02/2014, 05:20
... of the decrease in Jo, 68% of the decrease in Jp, 56% of the increase in the QH2 ⁄ Q ratio, 70% of the increase in Dw, 72% of the increase in the ATPin ⁄ ADPin ratio, and 59% of the decrease in ... reduction in Jo, 76% of the reduction in Jp, 68% of the increase in Dw, 88% of the increase in the ATPin ⁄ ADPin ratio, and 69% of the reduction in the ATPout ⁄ ADPout ratio The exception was the QH2 ... malate instead of succinate, control of the fluxes shifts from the respiratory chain to ATP synthesis Furthermore, the distribution of the control within the respiratory chain shifts from the part...
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Tài liệu Báo cáo Y học: Receptor crosstalk Implications for cardiovascular function, disease and therapy ppt
Ngày tải lên :
21/02/2014, 15:20
... strategies will continue to be directed mainly at containing these end-stage manifestations rather than combating the underlying cause of the disease It is nonetheless now evident that in the presence ... of the crosstalk leading to the inhibition of the b1-AR activity can be explained as resulting from a corelease of the endogenous hormones with the catecholamines in cardiomyocytes, like in the ... of these mechanisms have their origin in the CNS (Fig 3) These include: (a) the possible regulation of blood pressure in the cardiovascular centres of the brain through Ach release via cholinergic...
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Báo cáo " A brief comparison of Vietnamese intonation and English intonation and its implications for teaching English intonation to Vietnamese EFL learners " pptx
Ngày tải lên :
05/03/2014, 12:20
... low-falling, high-rising, lowfalling-rising, high-rising broken and lowfalling broken Except for the mid-level tone, all the other tones are denoted by diacritics over or under one of the vowels in the ... Rising /The First Rising Tone/Glide-up c Falling-Rising/Fall-Rise/Dive d Rising - Falling a The Falling/Glide-down In its shortest form, the Falling tone starts fairly high and then falls low In case ... "cautiously used" in Vietnamese than in other languages: In questions, for example, there is normal declination until the proximity of the sentence final question marker, where the rise begins; the overall...
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Báo cáo " A review of washback and its pedagogical implications " potx
Ngày tải lên :
05/03/2014, 12:20
... students In other words, the washback on the side of the educational setting is one coin with two sides, depending on the stakeholder’s point of view Pedagogical Implications By analyzing the possible ... refers to the extent to which a test influences within the classroom, mainly in the change or innovation of curricula and teachers’ methodologies and the influence of students’ learning Bailey ... researchers into the classroom in order to observe the effect of their tests in action.” In other words, washback validity deals directly with the extent to which the test meets the needs of students,...
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A Meta-Analysis of Fear Appeals: Implications for Effective Public Health Campaigns pdf
Ngày tải lên :
05/03/2014, 22:21
... popular at the time. 19-22 Beginning in the 1970s, cognitive perspectives gained favor in fear appeal theories, mirroring the cognitive revolution in the social sciences.10 More recently, there has ... information for the main effects and the interaction effects for each study are available from the authors upon request.) Ninety-three studies were included in the main effects analysis.28,29,58-63,65-68,70,71,77-150 ... clear whether interactions exist in the literature While the analysis of variance interaction test in this study indicated no significant interaction, the effects-coded model testing for PMT/EPPM...
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Cancer as a metabolic disease pdf
Ngày tải lên :
06/03/2014, 02:21
... grown in vivo It appears that the in vitro growth environment reduces Complex I activity and obscures the boundaries of the Crabtree and the Warburg effects The Crabtree effect involves the inhibition ... However, neither the EMT hypothesis nor the macrophage fusion hypothesis link the origin of metastasis to the Warburg effect or to impaired energy metabolism Recent findings of cardiolipin abnormalities ... will involve injury to the mitochondria in the affected cells The prevention of inflammation and damage to the tissue microenvironment will go far in reducing the incidence of most cancers Vaccines...
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Báo cáo khóa học: Disruption of the interaction between the Rieske iron–sulfur protein and cytochrome b in the yeast bc1 complex owing to a human disease-associated mutation within cytochrome b potx
Ngày tải lên :
07/03/2014, 15:20
... in pink, and the hinge region of the ISP is shown in white the integration or stability of the ISP within the bc1 complex In order to investigate its effect on the bc1 complex, we introduced this ... enzyme with their ISP in different conformations The mutation G167E could distort the hinge region of the ISP and hinder the movement of the headgroup Mutations in the hinge region of the ISP, which ... compensatory, because, in the revertants, the bc1 activity remained low and the instability of the complex persisted, as observed for the primary mutant In order to monitor the effect of the secondary...
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Báo cáo khoa học: Unravelling the functional interaction structure of a cellular network from temporal slope information of experimental data docx
Ngày tải lên :
07/03/2014, 21:20
... other methods that make use of the measured absolute values at each sampling time point For instance, the result in Fig is the same even if we choose any sampling time points within the time intervals ... which is included in the FNS at xi Based on the information of the FNS at xi, we can find the true network signs For instance, if the nonzero s( fi‘) in the FNS are all determined as É then S( ... sampling time points not overlap each other (Fig 9A) then we define the slope between these two time points as ‘clear’ since all possible increasing ⁄ decreasing slope combinations between the...
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Gender as a Health Determinant and Implications for Health Education pot
Ngày tải lên :
14/03/2014, 21:20
... more prevalent in women, there is not sufficient support for the biological-determinant hypothesis by referring back to the empirical finding that women are at increased risk for a specific health ... Dubbert, King, & Pinto, 1995) Determinants May Have Indirect Health Effects A determinant may indirectly affect a certain health outcome (see Figure 2) In this case, the effect of one determinant ... when these other determinants are considered Determinants May Interact With Each Other, and So Contextualize Health Effects Finally, determinants may interact or contextualize each other’s effect...
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