in this world nothing is certain but death and taxes benjamin franklin
Báo cáo khoa học: Liver receptor homolog-1 localization in the nuclear body is regulated by sumoylation and cAMP signaling in rat granulosa cells docx
Ngày tải lên :
23/03/2014, 06:20
... phosphorylation following 4b-phorbol 12-myristate 13-acetate (PMA) induction [18], and serine residues 238 and 243 in the hinge region of human LRH-1 are important in this PMA-dependent transactivation ... that lysine 173 and 289 are involved in the SUMO-1 modification in cells and that lysine 289 is the major target for SUMO-1 conjugation Multiple SUMO conjugation is associated with the targeting of ... whether cAMP signaling results in a global hyposumoylation of most substrates, including LRH-1, requires further investigation However, this may explain why forskolin could abolish the localization...
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Báo cáo y học: "Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study" pps
Ngày tải lên :
09/08/2014, 10:21
... synovial tissue were collected using 2.0 mm grasping forceps (Storz, Tuttlingen, Germany) and embedded in paraffin until analysis Paraffin-embedded, serial sections were stained with the following ... why HDC plus HSCT exhibited inferior efficacy in RA A common finding in autoimmune diseases is activation of autoreactive B lymphocytes, resulting in the formation of disease-specific autoantibodies ... Authors' contributions YKOT contributed to the acquisition of data, analysis and interpretation of data, and preparation of the manuscript RJV contributed to the design of the study and acquisition...
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Báo cáo y học: "TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways" pdf
Ngày tải lên :
12/08/2014, 14:20
... MyD88 is involved in TLR, but also in IRAK-1-mediated IL-1R and -18R signalling A role for IL-1 and IL-18 pathways in this response was excluded, as bronchoconstriction, inflammation, and protein ... inflammation and the production of Th2 cytokines by mediastinal lymph node T cells Interestingly, in the same mice, the levels of instructing cytokines were severely impaired Interestingly, inhalation ... the mucosa for incoming antigens Moreover, in response to LPS or HDM, TLR4+ SCs produced DCactivating cytokines such as GM-CSF in the airways This cytokine is likely to be involved in airway DC...
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English Presentation: International trade is encouraging but it is very risky and requires certain caution. Provide lessons the exporters must learn and security in payment exporters must know
Ngày tải lên :
18/05/2017, 13:19
... Transportation risk Transit risk is the risk of goods being damaged during shipment from the place of origin to the place of destination Failure in addressing transit risk may result in heavy replacement ... positive, and minimizes your risk However, few buyers will be willing to pay in advance because they concerns that the goods may not be sent if payment is made in advance At this point, exporter ... in political situations in the concerned importing and exporting countries Following are the factors, affecting the political situation: - Changes in the party in power in the concerned countries,...
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English is the most popular language in the world
Ngày tải lên :
09/04/2013, 08:49
... Questions and answers T/F exercises Multiple choice exercises Finding the topic sentences Finding synonyms and antonyms Blank filling Reordering exercises Completing exercises Matching exercises Finding ... provide his students with some questions or exercises focusing on reference and linking words Finding equivalence and completing text with missing linking words are strongly suggested in this case ... old in their homes by A mowing the lawns, doing shopping and cleaning up their houses B cooking, sewing or washing their clothes C telling them stories, and singing and dancing for them D taking...
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Tài liệu In this lab, 2 ISDN routers are required. If ISDN routers are not available, review the lab to become familiar with the process. An Adtran Atlas550 ISDN emulator is used to simulate the switch/ISDN cloud. pdf
Ngày tải lên :
21/12/2013, 19:15
... of interface even though a specific router may contain one An example of this might be an ISDN BRI interface The string in parenthesis is the legal abbreviation that can be used in IOS command ... that the interface is spoofing This provides a mechanism for the interface to simulate an active state for internal processes, such as routing, on the router The show interface command can also ... Specifying interesting traffic for DDR Traffic must be defined as ‘interesting’ to cause the DDR interface to dialup the remote router For the moment, declare that all IP traffic is interesting using...
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look at the important information in this header.1look at the important information in this header.We encourage you to keep this file on your own disk, keeping an electronic path open for the next readers. Do not remove this. **Welcome To The World o doc
Ngày tải lên :
06/03/2014, 23:21
... holding up the sky; timid in everyday life, but daring in days of battle; shrewd and clever in seizing the loose threads of ordinary life, but silly and stupid in distinguishing her own interests ... to go into all the episodes of this story, but the crisis is that Colonel Delmare is ruined, and his business affairs call him to the Isle of Bourbon He intends to take Indiana with him, but she ... having aimed at attacking institutions in her feminist novels She was wrong in protesting, as it is just this which gives her novels their value and significance It is this which dates them and...
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This World Is Taboo potx
Ngày tải lên :
23/03/2014, 00:20
... mountains in which the mine lay It tilted again, and swept onward over the mountaintops, and then tilted once more and went racing up the valley in which the landing-grid was plainly visible ... correct the results of incompetence in directing Med Service in this sector But it is always disheartening to have to labor at making up for somebody else's blundering, when there is so much new work ... communicator button and spoke into a microphone "Med Ship Aesclipus Twenty reporting arrival and asking coordinates for landing," he said matter-of-factly "Purpose of landing is planetary health inspection...
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Báo cáo hóa học: " Markedly impaired bilateral coordination of gait in post-stroke patients: Is this deficit distinct from asymmetry? A cohort study" ppt
Ngày tải lên :
19/06/2014, 08:20
... minutes, including the preparation time for the patient The post processing time was less than minutes including uploading, calculation and reporting In off-line analysis, only straight walking ... generating anti-phased stepping and increased strideto-stride inconsistency, as compared to the control group This results in increased PCI values (Table lower rows) Figure illustrates this point ... pathophysiology of freezing of gait in Parkinson’s disease Mov Disord 2008, 23(Suppl 2):S444-S450 Ustinova KI, Fung J, Levin MF: Disruption of bilateral temporal coordination during arm swinging in patients...
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information in this document is subject to change without notice. the names of companies, products, people, characters,
Ngày tải lên :
06/07/2014, 09:03
... Developing a Join Strategy ! Determining the Naming Structure ! Determining the Physical Topology ! Designing a Management and Security Strategy Lead -in In this module, you will learn about designing ... of designing and developing a metadirectory Define a Data Define a Data Model Model Determine a Determine a Naming Structure Naming Structure Lead -in Develop a Develop a Join Strategy Join Strategy ... data administrators to handle routine administration Assign access controls on the namespace and the administrative areas to protect the privacy of user data Avoid setting permissions on individual...
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Failure is the mother of successComment in this saying doc
Ngày tải lên :
22/07/2014, 04:20
... of this defect Day after day, he went to the sea, shouting and roaring with deafening sounds of waves and in the end he acquired a convincing and sonorous voice as he had wished The above saying ... lose hope and was determined to investigate the causes of his failure: he tried to better his soil, fertilizing his rice-fields with mush nitrogen and finally he succeeded in collecting tons of ... patience, persistence and will are important Drawing experiences from previous failures, we changed tactics and strategies and finally we will succeed Our success is due to our unflinching determination...
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Báo cáo y học: " TGF β-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7" pps
Ngày tải lên :
09/08/2014, 07:20
... synthesis and content in cartilage (a) PG synthesis was measured by 35SO42- incorporation into patellar cartilage days after interleukin-1 (IL-1) injection (CPM = counts per minute) PG synthesis increased ... TGF-β and Smad7 adenoviruses were injected days after IL-1 injection This combination turned out to be beneficial for PG synthesis and could still induce a significant increase in PG synthesis (80% ... Smad7, the lining appeared to be less sensitive to TGF-β-induced fibrosis The reduction of TGF-β-induced fibrosis was not optimal and resulted in only a partial block of the fibrosis This is likely...
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Báo cáo khoa học: "Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21" pdf
Ngày tải lên :
09/08/2014, 09:20
... that DCQ is a hypoxic cytotoxic compound that induces apoptosis in several murine and human cancer cell lines [4,5,8] This is our first attempt to understand the role of p53 and p21 in drug efficacy ... were obtained from ATCC and maintained in a humidified atmosphere of 5% CO2 and 95% air 10 mg of DCQ was dissolved in ml of DMSO and stored in a brown eppendorf at 4°C and then diluted in media ... (HIF-1a) mRNA and protein in the human colon carcinoma cell line T-84, and in EMT6 mouse mammary carcinoma cells and Lewis Lung Carcinoma (LLC) cells [4,8] We also showed that DCQ inhibited cell...
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Báo cáo y học: "Rheumatoid cachexia is associated with dyslipidemia and low levels of atheroprotective natural antibodies against phosphorylcholine but not with dietary fat in patients with rheumatoid arthritis: a cross-sectional study" pdf
Ngày tải lên :
09/08/2014, 13:22
... cm in women and 94 cm in men indicates low risk, 80–87.9 cm in women and 94–101.9 cm in men indicates intermediate risk, and a value Page of 11 (page number not for citation purposes) Arthritis ... in analyzing adipose tissue and an advisory role IH took part in the design of the study and has been senior advisor in all parts of the research and manuscript preparation All authors read and ... Tengstrand B, Cederholm T, Brismar K, Hafstrom I: Cachexia in rheumatoid arthritis is associated with inflammatory activity, physical disability, and low bioavailable insulin-like growth factor Scand...
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Báo cáo y học: "The World Trade Center Attack Disaster preparedness: health care is ready, but is the bureaucracy" pdf
Ngày tải lên :
12/08/2014, 18:21
... by buying equipment and stockpiling drugs prior to establishing a realistic policy and developing an infrastructure of real-time response Detection systems of incident reporting, Gram staining, ... history, but it took on a new meaning as of 11 September 2001 (it is ironic that this date corresponds to the emergency call sign of 911) Terrorism has in the past been local, but now it is international ... are caring and versatile groups, and are ready, willing, and dedicated to providing the best multifaceted care possible during unexpected disasters, but there must be effective frameworks in which...
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Ho chi minh was the communist leader of north vietnam from the end of world war II until his death in 1969
Ngày tải lên :
19/08/2016, 12:30
... Japanese forces in Indochina The Chinese Nationalists, who had broken with the Communists and been disturbed by the Viet Minh activities in both Vietnam and China, however, arrested and imprisoned Ho ... Minh) followed his studies in London and Paris during the 1910s He came to communism in France through his friend Marcel Cachin (SFIO) who was sent to Russia in 1917 during World War I Cachin ... recovering from tuberculosis In 1938, he returned to China and served as an adviser with Chinese Communist armed forces In Thailand Nachok is the village where Hồ Chí Minh stayed in 1928-29 during...
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Natural botanical products have a long history in the world and are featured in using a complex
Ngày tải lên :
03/11/2012, 09:54
... proliferation and promotion of apoptosis in this model Dietary supplement containing Schisandra chinensis has been shown to reduce prostate cancer cell growth and induce apoptosis by inhibiting androgen ... contain various anti-carcinogenic compounds including lunasin and lectins that were shown to induce apoptosis in malignant cells [13] As CKBM contains these compounds, this would partially explain ... diseases (e.g rheumatoid arthritis, menopausal symptoms, colds and flu etc) CKBM-A01 is a combination of herbs including Wu Wei Zi (Schisandra chinensis), Ginseng (Panax ginseng), Hawthorn (Fructus...
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