in the delta exoplanets worlds but not as we know them

... with previous in vivo studies indicating that aggrecan loss was reversible as long as the progression was not too advanced [2,4,36] In further support of these findings are studies in inflammatory ... Although assays for measuring sulphated glycosaminoglycans (S-GAGs) are available, these assays not distinguish between synthesis and degradation of the proteoglycans [19] Furthermore, they not distinguish ... synthesis, whereas proteoglycan synthesis was strongly attenuated In contrast, at the time of maximal aggrecanase activity, the proteoglycan loss was fully reversible These findings correlate well...

Ngày tải lên: 09/08/2014, 10:23

... staining cells has been reported [5] but, for unknown reasons, could not be repeated [4] In mice, increased SAβGAL staining has been reported in animals harbouring the Werner mutation and short telomeres, ... could exist in vivo but not provide any measure of their relative contribution to the aging process In the current study, publicly available microarray data describing both aging and in vitro senescence ... Given the expansion of the microarray field during the past years, resulting in an accumulation of expression datasets in the literature and public databases, we thought that sufficient data were...

Ngày tải lên: 14/08/2014, 16:20

... mean DTC, which increased the sample size, and thus also increased the power of statistical testing The remaining pairs of bars in Fig illustrate mean DTC for the task combinations in our previous ... steps in front of the first obstacle, and finished one step behind the last They walked at their preferred speed, and all succeeded in not touching the obstacles We quantified their performance as ... avoiding obstacles, engaged in a visual checking task, and/or kept a visual scene in memory The walking and each non-walking task were administered separately as well as concurrently For task...

Ngày tải lên: 19/06/2014, 08:20

... a SNP in the CXCR1 gene would also influence the host susceptibility to CP In this regard, the aim of this study was to investigate the association of the rs2234671 SNP in the CXCR1 gene in a ... allele frequency (MAF) was 0.087, and the genotype distribution of the rs2234671 SNP in the CXCR1 gene was consistent with the assumption of the Hardy-Weinberg equilibrium for the control (p = 0.1719) ... gingival margin to the base of the pocket), clinical attachment loss (CAL) (as the distance from the cement-enamel junction to the base of the periodontal pocket) and bleeding on probing (BOP) (registered...

Ngày tải lên: 11/08/2014, 07:21

... thrombo-embolectomy The use of temporary shunting of peripheral vasculature in order to maintain distal vascular perfusion is rarely employed in civilian surgical practice [2,3], however, it has been gaining ... definitive revascularisation which can be performed following fracture fixation Competing interests The authors declare that they have no competing interests Authors' contributions SAS was first assistant ... McIlrath E: The Belfast approach to managing complex lower limb vascular injuries Eur J Vasc Endovasc Surg 2006, 32(3):246-256 Consent Written informed consent was obtained retrospectively from the patient...

Ngày tải lên: 11/08/2014, 21:22

... Score in 28 joints calculated by using C-reactive protein; DAS28-ESR, Disease Activity Score in 28 joints calculated by using erythrocyte sedimentation rate Page of 2 Competing interests The authors ... PLCM: Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with ... Shadick NA, Weinblatt ME, Solomon DH: Pain persists in DAS28 rheumatoid arthritis remission but doi:10.1186/ar3393 Cite this article as: Yoshida K, et al.: Response to ‘Pain persists in DAS28 rheumatoid...

Ngày tải lên: 12/08/2014, 17:22

Ngày tải lên: 21/06/2014, 23:20

... which are basic passages established without using engineering structures and drainage and have rather large longitudinal inclines, which in most cases does not allow using them for the passage of ... forest The main factors determining the effect of a driving unit on soil are density of soil in the rut and its depth, which depend on the number of passages in the same track Investigations included ... included measuring the depth of ruts, degree of damage to the bearing surface and soil sampling Before the beginning of investigations the radius of turns, lengths of linear plots, weight and...

Ngày tải lên: 07/08/2014, 03:22

... age, but others were not trained There is no official swimming training in the school program in the Mekong River Delta It seems an irrational structure for children living in a floodplain as the ... in the high inundated areas are not attending their schools The beginning and the end of the rainy season are the best time for mosquito reproduction resulting in mosquito-based diseases A recurrent ... data showing high percentage of child deaths in the total the losses of life in the flood seasons in the MD Save the Children (2003) reported that the vast majority of the drowning deaths in recent...

Ngày tải lên: 18/10/2013, 12:15

... of adenine nucleotides, (b) the decrease in ATP and the increase in inosine, promoted by H2O2, cannot be explained solely by a change in the level of the enzymes more directly involved in the nucleotide ... adenosine deaminase; E5, purine nucleoside phosphorylase; E6, adenylate kinase; E7, adenosine kinase; E8, hypothetical enzyme recycling ATP Fig Dierential equations describing the uxes operating in ... Fig Inuence of the hypothetical enzyme (E8) recycling ATP, on the rate of synthesis of inosine Application of the theoretical model was performed with the MATHEMATICA-3.0 program, as described in...

Ngày tải lên: 17/03/2014, 10:20

... calnexin-containing but not in calnexin-deficient cells HPV16 E5 decreases HLA-I surface expression in calnexin-containing but not in calnexin-deficient cells CEM-C7 (calnexin) and CEM-NKR (no calnexin) ... E5 expression results in diminished HLA-I surface staining in cells expressing calnexin, but not in calnexin deficient cells D) The upper part of the blot shown in A was incubated with anti-HC-10 ... pCI) as the statistic D The p value of each single experiment was in all cases ≤ 0.001 sion As shown in Fig 2B no major difference in the expression level was found between both cells types We then...

Ngày tải lên: 18/06/2014, 18:20

... calnexin-containing but not in calnexin-deficient cells HPV16 E5 decreases HLA-I surface expression in calnexin-containing but not in calnexin-deficient cells CEM-C7 (calnexin) and CEM-NKR (no calnexin) ... E5 expression results in diminished HLA-I surface staining in cells expressing calnexin, but not in calnexin deficient cells D) The upper part of the blot shown in A was incubated with anti-HC-10 ... pCI) as the statistic D The p value of each single experiment was in all cases ≤ 0.001 sion As shown in Fig 2B no major difference in the expression level was found between both cells types We then...

Ngày tải lên: 20/06/2014, 01:20

... words in underline are phrases in examples below: The sun rises in the east Peter sat on a wall The girl with red hair is an artist The Phrase There are five commonly occurring types of phrase in ... Pointing out that “ she” functions in exactly the same way as “ The beautiful girl” and “ arrived” in exactly the way as “ has arrived” Concentrating on the similarity of function, they define ... Ex: The senile old man disease Many case of infectious A story as old as time The Phrase A noun phrase: A noun phrase consits of a noun and all it modifies Ex: The senile old man Many case of infectious...

Ngày tải lên: 13/07/2014, 23:26

... differences in the amount or localization of apoptotic cells during the beginning regression of the interdigital web Serial sagittal sections stained for activated caspase (aCasp3; red) in (b-d) ... hyperplastic brain phenotypes were observed at a low penetrance in Ptdsr-mutant mice (less then 4.5% of homozygotes), but these not resemble to any extent the brain-overgrowth phenotypes of caspase- ... 3d,j) In the most severe cases, expansion of brain tissue in mutant mice resulted in further perturbations of cortical structures (Figure 3d,j) Of note, a similar brain phenotype was observed in the...

Ngày tải lên: 06/08/2014, 18:21

... (2000) was revealed during passaging of HIV-1 in the presence of (-)-b-D-dioxolaneguanosine (DXG) This study showed that K65R and L74V were selected during passaging of HIV-1 LAI in the presence ... was due to an increase in the processivity of RT containing K65R+L74I mutant In summary, K65R+L74I virus showed a shorter lag period (similar to WT and point mutants), increased RC and increased ... are involved in coordinating the incoming triphosphate In the process, Arg72 donates hydrogen bonds to the a-phosphate and the ε-amino group of Lys65 donates hydrogen bonds to the g-phosphate These...

Ngày tải lên: 11/08/2014, 21:21

... phagocytosis in the diseased lung In contrast, the expression of the Hb monomers in the alveolar epithelial cells is in full agreement with previous findings on the airway epithelium [39] The distributions ... positivity, but when normalized against the loaded protein in the lane, no major difference between these diseases could be seen (not shown) However, if the total nitrotyrosine immunoreactivity in the ... the total protein pattern visualized by silver staining blot analysis The results showed clear nitrotyrosine positivity, especially in the epithelial cells and inflammatory cells but not in the...

Ngày tải lên: 12/08/2014, 11:22

... streptavidin-PE was added and incubated for 10 minutes The Bioplex-protein assay reader from Luminex was used The amount (pg) of cytokine/chemokine per mg protein (pg/mg) was calculated Cytokine and ... providing further evidence that the increase in uterus weight is indeed mediated via ERα (Figure 2a) Interestingly, after treatment with ERA-63, a more profound increase in uterus weight was observed ... In CIA, an increase in the arthritis score of the knee joints was associated with an increase in IL-1 mRNA levels [33] In addition, suppression of CIA was observed using antibodies against TNFα...

Ngày tải lên: 12/08/2014, 14:21

... similar to our findings (22.8 vs 22.3 in our study in the high morbidity group and 17.6 vs 18.8 in the low morbidity group) Another study associated increased length of stay in the ICU in association ... course? The baseline characteristics of the recipients are shown in Table The underlying liver diseases of the 144 patients are presented in Table The incidence of hepa- The analysis of the 147 ... with consecutive reintubations), ventilation days, serum peak values of bilirubin, alkaline phosphatase, alanine aminotransferase (ALT) and aspartate aminotransferase (AST); incidence of primary...

Ngày tải lên: 13/08/2014, 20:22

... given in [3] Anagrelide was administered orally The starting dose was 0.5 mg b.i.d If there was no response the dose was increased by 0.5 mg per day per week The mean maintenance dose was 2.3 ... response (PR) was defined as a reduction of the platelet count with at least 50 % of the baseline value, and treatment failure (F) as a reduction of the platelet count with < 50 % of the baseline value ... engineered TPO overproduction [27-29] Likewise, interleukin-6 (IL-6) levels might be raised in MPD [14] Since it is poorly known if therapy for thrombocythemia affects TPO levels, we assessed the...

Ngày tải lên: 03/11/2012, 10:52

... BRAND Line Extensions Line Extensions in existing in existing Product Class Product Class Stretching the Stretching the Brand Vertically Brand Vertically in existing in existing Product Class Product ... AVSs since they know the company producing them That is the source of the consumers’ trust for the Company’s products Furthermore, they know that the company produces not only AVSs but also other ... only few big companies offering the same products dominating the whole market Therefore, the bargaining power of buyers is low Bargaining power of suppliers In the AVS industry, although domestic...

Ngày tải lên: 13/04/2013, 10:29