important fungal diseases in humans

Ngày tải lên: 13/08/2014, 03:20

... treatment ingestion. After eating, an increase in heart rate occurred in all three treatment groups. The increase in heart rate does not coincide with the pharmacokinetics including blood ... caffeine user group in response to the product containing caffeine and p-synephrine. The results of this study in- dicate that ingestion of a product containing bitter orange extract, caffeine ... JP, Muller GJ. Coronary spasm and thrombosis in a bodybuilder using a nutritional supplement containing synephrine, octopamine, tyramine and caffeine. So African Med J. 2008; 98: 372-373. 22....

Ngày tải lên: 25/10/2012, 11:10

... containing isoamyl nitrite as a main component. b) In the commercial products of an alkyl nitrite, small amounts of corresponding alkyl alco- hol, the decomposition product, are contained. Since ... nitrites; their boiling points are 98, 78 and 67 °C, respectively. Amyl nitrite is being widely used as a detoxicant for cyanide poisoning, because alkyl nitrites oxidize hemoglobin in erythrocytes ... solution (2 mg/mL), and kept airtightly in a refrigerator. A 5-àL volume of the above solution is placed using a microsyringe in a glass vial containing 1 mL of dimethyl sulfoxide (DMSO), capped...

Ngày tải lên: 18/10/2013, 00:15

... solution containing a large amount of the derivatization reagent has to be injected into GC/MS, resulting in the marked contamination of the ion source of an MS instrument.  e lighting-up time ... mucosa and the skin results in its poisoning. In the murder terrorism with VX taking place in Osaka, Japan, 1994, VX was sprayed on the back of the neck of the victim using a syringe (the exposure ... stockpiling and use are being prohibited by the CWC international treaty as a chemical weapon together with those of sarin and soman. In addition, even material com- pounds for VX synthesis are being...

Ngày tải lên: 18/10/2013, 00:15

... conditions; an Autosystem XL (Perkin Elmer, Wellesley, MA, USA) and an FID were used. Column (oven) temperature: 50°C (2 min) →20 °C/min→200 °C(0.5 min)→5 °C/min→ 300 °C(5 min); injection temperature: ... 11-nor-9-carboxy-∆ 9 - tetrahydrocannabinol in urine. J Anal Toxicol 8:255–259 13) Foltz RL, McGinnis KM, Chinn DM (1983) Quantitative measurement of ∆9-tetrahydrocannabinol and two ma- jor metabolites in physiological ... acid measured by GC/MS were 22 ng/mL in urine and 0.6 ng/g in the liver. Case 2: A paper factory worker was killed by being caught in a machine during working with it.  e concentrations of ∆ 9 -THC-11-oic...

Ngày tải lên: 24/10/2013, 19:15

... or dihydrocodeine is commonly included in over-the-counter drugs of antitussives. > Figure 3.1 shows metabolic pathways of morphine, heroin and codeine. Since morphine and codeine are  nally ... containing poppy seeds [9]. It should be noted that an amount of codeine comparable to that of morphine are also included in the poppy seed- containing foods [10].  e half-life of heroin disappearance ... tetrahydropapavero- line in Parkinsonian patient undergoing L-3,4-dihydroxyphenylalanine therapy: a possible biosynthetic path- way of morphine from L-3,4-dihydroxyphenylalanine in humans. J Pharmacol...

Ngày tải lên: 24/10/2013, 19:15

... Table 5.1, clinical symptoms according to the concentrations of methemoglobin are pre- sented. ⊡ Table 5.1 Clinical symptoms appearing according to methemoglobin concentrations Methemoglobin concentration ... Cyanosis in infants caused by nitrates in well water. JAMA 257:2788–2792 12) Fan AM, Steinberg VE (1996) Health implications of nitrate and nitrite in drinking water: an update on methe- moglobinemia ... containing nitrate salt can be considered. However, a form or a product con- taining nitrate ingested could not be speci ed in the present poisoning case. Notes a) When nitrite is present in blood,...

Ngày tải lên: 24/10/2013, 19:15

... determination of methemoglobin in blood containing carboxyhemoglobin. Forensic Sci Int 17:177–184 7) Sato K (1983) A method for determination of methemoglobin in blood containing carboxyhemoglobin. ... Microdetermination of oxyhemoglobin, methemoglobin and sulfhemoglobin in a single sample of blood. J Biol Chem 126:655–662 2) Leahy T, Smith R (1960) Notes on methemoglobin determination. Clin Chem ... 8.68.6 â Springer-Verlag Berlin Heidelberg 2005 II.8.6 Methemoglobin by Keizo Sato Introduction Determination of methemoglobin ( Met-Hb) in blood is important for the diagnosis of poison- ing by...

Ngày tải lên: 24/10/2013, 19:15

... cocaine inhalation; the ratio was 10.6 on average for urine sampled 0–8 h a er the inhalation.  e ratios increased according to the increase in time interval between the inhalation and samplings ... GC/MS analysis for cocaine and its main metabolites, such as ecgonine methyl ester ( EME) and benzoylecgonine ( BE), in urine and blood, are presented; a fatal cocaine poisoning case, which the ... cocaine in urine was as much as 8.5 % ( > Table 4.1). According to human experiments, the urinary ratio of BE to cocaine was reported to be 5.9 on average for urine sampled 0–1 h a er cocaine...

Ngày tải lên: 29/10/2013, 01:15

... Figure 5.2 223 In two autopsy cases of pentazocine poisoning, its concentrations were 9.2 and 3.3 àg/mL in blood, 43 and 34 àg/g in the liver, and not detectable and 4.5 àg/mL in urine, respectively ... 285 plus 217 (pentazocine) were used at the retention times of 3–7 min and 7–8 min, respectively. The amount of pentazocine and IS spiked into 1 mL of blank whole blood or urine was equally 50 ng. ⊡ ... being analyzed by GC [1–4], HPLC [5–7] and GC/MS [8]. In this chapter, a simple method for GC/MS analysis of pentazocine in human whole blood and urine is presented. Structures of pentazocine...

Ngày tải lên: 29/10/2013, 02:15

... methamphetamine. However, in recent years, it has been increasing markedly; 3,500 tablets of LSD were seized in 1996, while 53,043 tablets in 2000 (about 15-fold increase), arousing a serious concern ... obtained by oral administration of as small as 2075 àg of LSD. e ab- sorption of LSD from the digestive tract is rapid and distinct visual hallucination takes place 45 min–1 h a er oral intake ... powerful hallucinogenic drugs of abuse. LSD was explosively abused in U.S.A. in the latter half of the 1960s. In Japan, the amount of seizure of LSD is much smaller than that of methamphetamine. However,...

Ngày tải lên: 08/11/2013, 01:15

... Services Administration (SAMHSA) is 250 ng/mL. Symptoms, and toxic and fatal concentrations MDMA causes increased catecholamine (including serotonin) release and blockade of reuptake resulting in cardiac ... obtained from clandestine tablets, are shown in > Fig. 7.3.  e MDAs produce EI mass spectra characterized by intense ions resulting from the α-cleavage of the amines and some less intense ... drugs are being usually sold in tablet forms in black markets.  e tablets are o en imprinted with various kinds of graphic designs and commercial logos, including the 3-diamond (“Mitsubishi”...

Ngày tải lên: 08/11/2013, 01:15

... dichloromethane containing cyclized GHB is more than 100 àL in the vial, the proportion of dichloromethane gas, being contained in the headspace vapor to be injected a er heating, becomes too ... awakening ranged from 30 to 190 min (average: 120 min). Serum GHB levels did not correlate with the degree of coma or the time until awakening. GHB levels in urine collected within 30 min a ... sealed with an alu- minum cap. vii.  e vial is heated at 100 °C for 15 min on a heating block and 1 mL of the headspace gas is injected into GC. 2.92.9 â Springer-Verlag Berlin Heidelberg 2005 II.2.9...

Ngày tải lên: 08/11/2013, 01:15

Ngày tải lên: 11/12/2013, 23:55

... Springer-Verlag Berlin Heidelberg 2005 II.3.1 Phenothiazines by Akira Ishii and Yoshinao Katsumata Introduction Phenothiazine drugs, including chlorpromazine and levomepromazine, have been being ... Poisoning due to psychotropic agents. Adverse Drug React Acute Poisoning Rev 4:83–126 3) Geraut A, Kintz P, Traqui A et al. (1994) Toxicological findings in a fatality involving chlorpromazine. ... (1 min) →15 °C/min e → 290 °C (10 min); injection temperature: 270 °C; interface temperature; 270 °C; carrier gas: He; its  ow rate: about 1.5 mL/min; injection: splitless mode for 1 min followed...

Ngày tải lên: 15/12/2013, 12:15

... Igarashi Introduction Butyrophenone drugs including haloperidol are being widely used in the  eld of psychiatry.  e acute butyrophenone poisoning incidents sometimes take place; in such cases, ... solution, because it increases extraction e ciency due to its salting-out e ect. c)  ere is a report using a haloperidol analog as IS, in which chlorine is substituted for the  uorine; but this ... temperature: 100 °C (1 min) → 30 °C/min → 270 °C (30 s) → 5 °C/min → 290 °C (5 min); injection temperature: 260 °C; separator tempera- ture: 280 °C; carrier gas: He; its  ow rate: 1.5 mL/min; MS ionization...

Ngày tải lên: 15/12/2013, 12:15

... carbamazepine obtained by GC/MS. A: amitriptyline, B: mianserin, C: nortriptyline, D: imipramine, E: desipramine, F: promethazine (IS), G: setiptiline, H: carbamazepine, I: maprotiline, J: clomipramine, ... also in- cluded in this chapter. GC/MS analysis Reagents and their preparation ã Amitriptyline, carbamazepine, clomipramine, desipramine, imipramine, maprotiline, mi- anserin, nortriptyline ... solvent can be chosen according to the kind of a target drug. e) Imipramine and amitriptyline are metabolized into desipramine and nortriptyline, respec- tively, in a human body. Both metabolites...

Ngày tải lên: 15/12/2013, 12:15

Ngày tải lên: 15/12/2013, 12:15

Ngày tải lên: 15/12/2013, 12:15

Ngày tải lên: 15/12/2013, 12:15