... from data in the RCT The survival of patients receiving ASC/BSC was calculated from the survival ofthe patients in the cetuximab monotherapy arm ofthe RCT The data from the monotherapy arm NICE ... guide for healthcare professionals Information for people with metastatic colorectal cancer and their carers (‘Understanding NICE guidance’) Details of all the evidence that was looked at andother ... evidence from the bevacizumab studies and noted that the age ofthe population in the largest study was lower than the age of patients normally receiving chemotherapy in England and Wales However,...
... evidence forthe optimal period oftreatmentand number of treatments? We found evidence forthe efficacy of shorter treatment protocols than the 4–6 months recommended by the ICS The basis ofthe ... the differences in outcome The expertise of health professionals may vary and also the quantity and quality ofthe educational information about the condition and PFM function The impact of these ... andother physical therapies forthetreatmentof female SUI [13] and UI [1416] has been the subject of previous systematic reviews All of these reviews limited their inclusion criteria to randomized...
... choice and loading ofthe NM is a compromise between the required efficiency ofthe converter andthe market price ofthe NM However, the application of noble metals forthetreatmentof exhaust ... are formed in adsorption of reactant molecules on the semi-conducting surface; the formation of these is a function ofthe electronic properties ofthe solid, andthe structure and kind of bonds ... begins with the adsorption of CO and O2 on the Nguyen The Tien 29 Synthesize and investigate the catalytic activity of three-way catalysts based on mixed metal oxides forthetreatmentof exhaust...
... concentrations of A:B determined by the relative association constants (K) of A:E (KA:E) and B:E (KA:B) andthe velocity (ν) of production of A from B:E (νA) and B from A:E (νB) Removal or addition of either ... strongly suggests otherwise, the immune system is thought to "control" viruses What practical meaning does "immune control" have forthe individual? There is no argument for HBV, andother viruses, ... dementia in the young represents "proof of principle" of virus-caused dementia, raising the possibility other forms of virus related dementia exist Although highly active antiretroviral therapy (HAART)...
... concentrations of A:B determined by the relative association constants (K) of A:E (KA:E) and B:E (KA:B) andthe velocity (ν) of production of A from B:E (νA) and B from A:E (νB) Removal or addition of either ... strongly suggests otherwise, the immune system is thought to "control" viruses What practical meaning does "immune control" have forthe individual? There is no argument for HBV, andother viruses, ... dementia in the young represents "proof of principle" of virus-caused dementia, raising the possibility other forms of virus related dementia exist Although highly active antiretroviral therapy (HAART)...
... bending ofthe hardware, and segmental kyphosis after a caudad screw in the lumbar construct broke And they noted that untreated anterior instability, and pre-stressing ofthe screws when the rods ... drafting the manuscript and designing of data and revising it critically, KCN has contributed in acquisition of data and analysis and interpretation of data, and JHY has contributed in acquisition and ... through the rod pusher to bring the vertebra back to the rod Gentle distraction at the level ofthe fracture followed, restoring tension to the posterior longitudinal ligament (ligamentotaxis) and thereby,...
... perform Hip and knee flexion were scored similarly For analysis, results on the lock and key test were categorized into quartiles, and range of motion ofthe shoulders Louie and Ward Health and ... functioning, before they had the physical examination and performance testing Analytic framework To maximize the specificity ofthe association between physical performance tests and self-reported ... BMI, and SMI To determine if other physical performance tests were associated with any ofthe three self-reported functional limitations, we then added the lock and key test, shoulder range of...
... contraindication for enrollment in the VNS studies of patients with TRD, there have been no studies ofthe use of VNS therapy among pregnant patients A report of eight pregnancies in patients receiving VNS therapy ... Inc., collected the data for this pilot study and encouraged the authors to submit this case report to help increase the understanding of VNS therapy and pregnancy References Andersson L, Sundstrom-Poromaa ... DSM-IV diagnosis of unipolar depression, was enrolled in the acute and long-term phases ofthe pilot study of VNS therapy for TRD At acute-phase study entry, she was noted to be obese and to have...
... of OA but not normal cartilage [36] Both IL-1β and TNF-α stimulate their own production andthe production ofother cytokines (e.g IL-8, IL-6, and leukotriene inhibitory factor), proteases, and ... [70] and IL-1αinduced PGE2 production [71] in a dose- and MW-dependent manner; the higher the MW and concentration, the more potent the inhibition Intra-articular injection of HA in the temporomandibular ... levels of prostaglandin F2α, 6-keto-prostaglandin F1α, and leukotriene C4 [72] In synovial fluid from the knees of patients with OA and RA, intra-articular HA reduced the levels of PGE2 [73,74] and...
... during the 5-day treatment period Patient compliance with thetreatment regimen was excellent Patients expressed satisfaction with the conduct ofthe study as well as the delivery ofthe radiotherapy ... Group (EBCTCG): Effects of radiotherapy andof differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview ofthe randomized trials Lancet ... selection of patients for Page of 10 APBI [22,23], and these guidelines formed the basis for patient selection in the EBT multicenter study [20] Ofthe 65 patients that met the initial screening...
... returned in 32 out ofthe 40 patients (80%) The median age at the time of radiotherapy was 44 years (range 17-83 years) The tumor manifestation was on the right eye in 16 patients and on the left eye ... Kuhn and her team of technicians for excellent patient care Authors’ contributions SC, JD and SR treated the patients SA, SR and SC collected the data SC and SA evaluated the dataset and performed ... new headaches, and three of recurrent hyperlacrimation ofthe irradiated eye, one with change of taste perception None ofthe patients developed dysfunctions ofthe pituitary gland, neuropathy,...
... was stopped after first cycle of chemotherapy at a dose of 43 Gy because of toxicity and old age ofthe patient The intensity of chemotherapy was reduced in smoker and non-smokers due to hematologic ... difference between the three treatment protocols On theother hand only 10 patients were treated outside the RTOG protocol andthe differences between the three protocols in dose and chemotherapy are ... factor forthe development of anal cancer is well known, no data about the influence of smoking during combined radiotherapy on the outcome after therapy exist as of now The exact role of smoking...
... V20 of 59% and V10 of 73% It is possible that sparing ofthe femoral heads and/ or other organs comes at the cost of increasing dose to the iliac crests The results of our study reinforce the ... M: Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in thetreatmentof locally advanced anal cancer: results of a Page 10 of 11 (page number not for citation purposes) ... apart form the ovaries, the bone marrow is the most radiosensitive pelvic tissue [28], and concurrent chemotherapy likely lowers this threshold dose and is in itself myelotoxic The issue of chemotherapy-induced...
... cells as well as the effect of IL-1β and TNF-α on cytokine gene expression andthe expression ofthe associated receptors and endogenous antagonists There Page of 10 (page number not for citation ... and a downregulation of aggrecan and collagen types I and II [7] In this study, we have expanded the investigation to include the effect of TNF-α on matrix and MMP gene expression in normal and ... IL-1β may be involved in regulation of themselves and each otherand their respective receptors Page of 10 (page number not for citation purposes) Materials and methods Tissue source All human...
... dexamethasone and rituximab, remaining in CR for 48 months He died at 73 years of age for sepsis during support therapy for t-MDS Other two patients have died: one for acute renal failure and one for ictus ... utilized in the majority of patients during FCR treatment, and in all of them after 90 Y-RIT Despite the high incidence of grade or neutropenia there were no patients requiring hospitalization for infection ... Y-RIT and disappeared with itraconazole treatmentOther previous studies have already shown the low percentage of patients requiring hospitalization for infections [3,5] and a favorable safety profile...
... standards Therefore, the relapsed and refractory AML was still sensitive to alternative chemotherapy The CR rate of CAG (56.7%) for new AML appears to be slightly lower than the CR rate of standard ... groups for meta-analysis Another seven studies did not specify AML status ofthe rest 117 patients These 117 patients were therefore excluded for this comparison (Table 3) The heterogeneity test of ... study, we performed a systematic review and meta-analysis to assess the overall treatment efficacy andthe adverse events ofthe CAG regimen Materials and Methods Data source The databases of PubMed,...
... models Therefore, the inhibition of proinflammatory cytokines may provide an important therapeutic approach forthetreatmentof OA Clinical trial data on cytokine inhibitors forthetreatmentof ... of Procter & Gamble Pharmaceuticals during the performance of these studies and received 100% of their compensation from the company Authors' contributions KKB, SAH and EBH performed all ofthe ... 0.05) between the vehicle and drug treatment groups contributes to the development and maintenance of neuropathic pain by inducing the synthesis of inflammatory cytokines andother neuroactive...
... three months oftreatment Between the commencement ofthe new psychotropic treatment regimen in October 2007 andthe significant improvement ofthe depressive symptoms as described above, the arthritis ... specific treatment (DMARDs and analgesics) had not changed While her CRP levels were 32 mg/L before the start ofthe new psychotropic treatment regimen, they dropped continuously to 13 mg/L Page of ... long before and after the clinical improvement This leaves us to the discussion ofthe anti-inflammatory effects of antipsychotic medication on CRP levels and a patient’s clinical symptoms The literature...
... analysis and interpretation ofthe data, and drafting ofthe article SJ and CS contributed to the conception and design ofthe work, sampling of data, interpretation ofthe data, and revision ofthe ... article for content SZ contributed to the conception and design ofthe work, interpretation ofthe data, and revision ofthe article for content K-DW contributed to the analysis and interpretation of ... ofthe data, revision ofthe article for content, and approval ofthe version to be published DJ contributed to the conception and design ofthe work, sampling of data, interpretation of the...
... Potaptchik and Ruth Lucio and Benjamin Nganda for their efforts in gathering cost data at the country level; and Tessa Tan Torres for her input in the development ofthe methods used The work represents ... performed the analysis and drafted the manuscript SE and BJ contributed to the selection of variables and model applications DE participated in the development ofthe methodology, selection ofthe ... gives the median and not the mean The smearing method described by Duan (1983) corrects forthe back transformation bias [74] This was done by multiplying the anti log ofthe product ofthe model...