... further discuss the implications on the requirements of PUS tagging Categorial Fluidity and Shift Very often when a verb is nominalised, it loses part of a verb's syntactic features For instance, a ... each tag consists of a letter code for the general classification (i.e noun, verb, etc.) of the word, and another for the sub-classification according to the particular context For example, when ... analysis of the data shows that about 58% of the words have r > 0.3, that is, verb usage at least doubles noun usage for these words About 23% have r between —0.3 and 0.3 These are the words of which...
Ngày tải lên: 08/03/2014, 21:20
... range of values for a-helix structure, while w angles for Leu14 and Arg16 are considerably close to the range of values for 310 helix Additionally, Leu14 possess a u torsion angle almost typical for ... (84% of residues), which is considered to be the active conformation of the hormone [38,40] The changes engineered in the sequence of the peptide, either through the nature of the side chain of ... 3JHNHa, and u vs w plots, Fig S2) imply a conformational preference for an extended structure The unambiguous conformational preference for helical structure for the C-terminal 10-peptide is manifested...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo sinh học: "A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases" docx
... proteins [15-17] The former approach requires large amounts of sera individually pre-adsorbed with E coli phage lysates for reduction of background; the latter require the purification of proteins encoding ... control target The mean OD of HD and the OD of one seronegative patient (#4) are also shown The use of sera from NSCLC patients for screening is due to higher frequency of Ab against these shared ... implications for classification of prostate cancer from non-malignant cases Journal of Translational Medicine 2011 9:43 Submit your next manuscript to BioMed Central and take full advantage of: ...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases" ppt
... proteins [15-17] The former approach requires large amounts of sera individually pre-adsorbed with E coli phage lysates for reduction of background; the latter require the purification of proteins encoding ... control target The mean OD of HD and the OD of one seronegative patient (#4) are also shown The use of sera from NSCLC patients for screening is due to higher frequency of Ab against these shared ... implications for classification of prostate cancer from non-malignant cases Journal of Translational Medicine 2011 9:43 Submit your next manuscript to BioMed Central and take full advantage of: ...
Ngày tải lên: 20/06/2014, 03:20
báo cáo khoa học: " Physician attitude toward depression care interventions: Implications for implementation of quality improvement initiatives" potx
... diagnosed, it is often within the context of a visit for another problem Further, patients diagnosed with depression may come in for follow-up visits for other chronic conditions or for acute problems ... see you for this."' Insurance coverage was often insufficient to meet the needs of patients with depression Physicians said that mental health visit limits and high out -of- pocket costs for mental ... comprehensive framework for health services for the chronically ill, have been promoted to address barriers and improve the quality of depression care [8-13] There are six elements of the CCM: delivery...
Ngày tải lên: 11/08/2014, 16:21
Báo cáo y học: "Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes" pdf
... School of Biomedicine, Faculty of Medical and Human Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK and 2Faculty of Life Sciences, Michael Smith Building, University of Manchester, ... that for correct functioning of an engineered IVD it is essential for the implanted cells to possess the correct phenotype Importantly, for stem cells-based tissue regeneration it is therefore ... differences in the transcriptional or protein profiles of IVD cells and AC cells Hypoxia inducible factor isoforms (HIF1A and HIF1B), glucose transporter type Page of 20 (GLUT-1), matrix metalloproteinase...
Ngày tải lên: 12/08/2014, 11:23
Báo cáo y học: "Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery" doc
... features of super ligands are of significance for selecting and/or designing multipotent agents Of course, the new strategy should be treated with wariness, because of the potential side effects of ... Number of carbons atoms 0.943 -0.228 Oxygens Number of oxygen atoms 0.425 0.793 Nitrogens Number of nitrogen atoms 0.475 0.324 Sulfurs Number of sulfur atoms 0.141 -0.009 Phosphorus Number of phosphorus ... 0.162 0.617 Halides Number of halide atoms 0.076 -0.170 DoubleBonds Number of double bonds 0.527 0.378 TripleBonds Number of triple bonds -0.009 -0.109 RadOfGyration Radius of gyration 0.888 0.004...
Ngày tải lên: 14/08/2014, 08:20
Role of hydrogen sulfide in the cardiovascular system implications for treatment of cardiovascular diseases
... Biosynthesis of H2S in mammals Figure 1.4 Catabolism of H2S in mammals Figure 1.5 Origins and disposal routes of H2S Figure 1.6 Effect of H2S on electrophysiology of heart Figure 1.7 Mechanisms of H2S-induced ... mechanisms of H2S may include suppression of β-adrenergic function 94 , inhibition of Na+/H+ exchanger (NHE) activity 115 , opening of KATP channels and blockade of LTCC 85, attenuation of endoplasmic ... by inhibition of pro-apoptotic factor Bad, upregulation of pro-survival factors Bcl-2 and Bcl-xL, and an upregulation of HSPs In addition, COX-2/PGE2 pathway 114, 119 , prevention of intracellular...
Ngày tải lên: 01/10/2015, 17:27
Báo cáo Y học: Regulation of a1,3galactosyltransferase expression in pig endothelial cells Implications for xenotransplantation doc
... (Fig 3B) The lack of TATA or CAAT-boxes together with the presence of many Sp1 binding sites, as observed for promoter B, is a characteristic of ÔhousekeepingÕ genes For most of these genes, transcriptional ... prepared by mixing 0.5 lg of luciferase construct and 0.25 lg of pCH110 plasmid diluted in 30 lL of serum-free medium and lL of SuperFect reagent (Qiagen) per well After 5–10 of incubation at room ... strong homology of exon sequences with a portion of the porcine invariant chain gene [21] could be responsible of the isolation of the false positive clones from the library To search for preferred...
Ngày tải lên: 08/03/2014, 16:20
Rural and Micro Finance Regulation in Ghana: Implications for Development and Performance of the Industry ppt
... Registration of RMFIs 31 B Regulation of Small Business Activity 31 C Financial Contracts 32 V Assessment of Impact of Regulation on the Evolution of Microfinance ... published as part of research on the implications of legal and regulatory structures for the development of microfinance institutions in African countries This research is a collaborative effort between ... and Micro Finance Regulation in Ghana: Implications for Development and Performance of the Industry By William F Steel & David O Andah June 2003 Foreword his country study is one of three being...
Ngày tải lên: 22/03/2014, 21:20
Báo cáo khoa học: Regulation of the muscle-specific AMP-activated protein kinase a2b2c3 complexes by AMP and implications of the mutations in the c3-subunit for the AMP dependence of the enzyme docx
... Regulation of AMPK a2b2c3 complexes by AMP K Lindgren et al all of which are required for its activity [8,9] In the mammalian genome, two isoforms of the a-subunit (a1 and ... b2 isoforms [23] The present study describes bacterial expression of AMPK a2b2c3 trimers, and provides the first characterization of the enzyme kinetic parameters and regulation mechanisms for ... AMPK subunit isoform exhibiting strictly restricted tissue-specific expression Furthermore, in both human and rodent skeletal muscle, c3 primarily forms complexes with the a2 and b2 isoforms [23,24]...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo hóa học: " ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency" potx
... for 35 cycles of 94°C for minute 15 seconds, 59.5°C for minute 15 seconds, and 72°C for 40 seconds Measurement of VP16 gene and competitor PCR product yields was performed by a modification of ... recovers 50% of the total DNA Thus, ~15 µg of DNA was present in a single TG, and the input of 0.1 µg of TG DNA per PCR contains ~1/150th (0.1 µg out of 15 µg) of the total number of HSV-1 genomes ... film of mice at day p.i (n = per group) d The percentage of mice that survived until day 60 p.i e The mean ± standard error of the mean duration of survival of those mice that survived for less...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo y học: "α Impact of VIP and cAMP on the regulation of TNF-α and IL-10 production: implications for rheumatoid arthritis" pps
... a density of × 105 cells/well, were stimulated by ng/ml LPS in the presence or absence of 10–6 M VIP IL-10 modulation of VIP regulation of TNF-α production was assessed by addition of 10 µg/ml ... inhibitor of LPSinduced TNF-α, whereas IL-10 is relatively unaffected The slight inhibition of IL-10 by elevation of cAMP is thought to be a consequence of the potent inhibition of TNF-α The failure of ... stimulated with ng/ml LPS in the presence or absence of 10–6 M VIP TNF-α modulation of VIP regulation of IL-10 production was assessed by addition of 10 µg/ml neutralising anti-TNF-α (A2) or 10 ng/ml...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis" ppt
... al.: Development of criteria for the classification and reporting of osteoarthritis Classification of osteoarthritis of the knee Diagnostic and Therapeutic Criteria Committee of the American Rheumatism ... begins at the early stage of the disease and is crucial for progression of the synovitis [13] Vascular endothelial growth factor (VEGF), which has five different isoforms (VEGF121, VEGF145, VEGF165, ... 220 µM of dNTPs and unit of ExTaq DNA polymerase (Takara Bio Inc.) The thermal cycle was minute at 94°C, minute at 62°C for ADAMs 8, 9, 10, 12, 17, 20, 21, 28 and 30, 67°C for ADAM15, 64°C for VEGFR-1,...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFκB: implications for rheumatoid arthritis" docx
... rate-limiting for the expression of chemokines after T-cell contact, with particular reference to the transcription factor NFκB, in order to gain insight into the regulation of chemokines at sites of inflammation ... differential utilization of NFκB for the expression of CC and CXC chemokines in this system We also examined the role of NFκB in the Tck-cell contactdependent production of chemokines in monocytes ... contact-dependent regulation of macrophage chemokine production is a general property of activated T cells Several other groups have also shown the importance of T-cell contact in regulating the production of...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration" ppt
... addition of exogenous IL-1β for 48 hours resulted in a statistically significant upregulation of TNF-α and TNF-R2 genes in both normal and degenerate samples (P = 0.05) (Figure 3b) The upregulation of ... be involved in the Page of 10 (page number not for citation purposes) onset of cartilage degradation and degeneration [27] The precise significance of the upregulation of TNF-R2 by TNF-α in NP ... addition of IL-1β in either normal or degenerate samples Effect of tumour necrosis factor-alpha on expression of interleukin-1 and interleukin-1 receptors The addition of recombinant TNF-α for 48...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: " Does psychopathology at admission predict the length of inpatient stay in psychiatry? Implications for financing psychiatric services" ppsx
... the amount of explained variation or that were considered to be important determinants of LOS were for instance: type of admission [9], comorbidity, severity of illness [22] or level of functioning ... 5% of the variation of LOS The consideration of syndromes Warnke et al BMC Psychiatry 2011, 11:120 http://www.biomedcentral.com/1471-244X/11/120 Page of 10 Table Prediction of the length of stay ... Psychiatric hospitals of the Canton of Zurich cover additional information (e.g data on psychopathology or severity of illness) The physicians in charge assess all medical data on the basis of a manual...
Ngày tải lên: 11/08/2014, 15:22
the development of an instrument to measure individual dispositions towards rules and principles; with implications for financial regulation
... department, for funding my PhD I also would like to express my gratitude to the Institute of Chartered Accountants of Scotland for providing support in the form of Seed-corn funding for some of the ... Society of Edinburgh Thesis Submitted in Fulfilment of the Requirements for the Degree of Doctor of Philosophy (PhD) Adam Smith Business School College of Social Sciences University of Glasgow ... exploration of the predictive power of the DRP instrument will for the purposes of this PhD project be limited, for the most part, to that necessary to convince one of the ‘predictive validity’ of the...
Ngày tải lên: 22/12/2014, 21:58
Ecological Services Analysis Some Evidences and Policy Implications for Socio- Economic Development of Ecosystems of Việt Trì City, Phú Thọ Province
... Orientation for development of the ecosystems of Viet Tri city for maximal development of ecological services [1, 3, 4-6] - Residential ecosystem should be created for full use of all the regulating services ... important level of the services of each ecosystem is presented below assessment table (Table 1) Table lists the various important levels of ecological services of the main ecosystems of Viet Tri ... maximum all services of the regulating services groups, the supporting services groups and cultural services groups - River ecosystem should be created for full use of the provision services groups,...
Ngày tải lên: 24/06/2015, 08:16
Environmental barriers to trade of the united states and implications for vietnam
... Process and Challenges, Hanoi 14 Damien J Neven (2000), Evaluating the effects of non-tariff barriers, University of Lausanne 15 The Australian APEC Study Centre-Monash University (2003), European ... mại quốc tế hàng hóa dịch vụ Mỹ từ tháng năm 2010 đến tháng năm 2012 Nguồn: http://www.census.gov/foreign-trade Nhìn vào biểu đồ ta thấy đường nhập nằm phía trên, có xu hướng lên có độ dốc so với ... soát nhập sản phẩm liên quan đến môi trường bảo vệ ngành sản xuất có liên quan nước Được Công ty Ford Việt Nam tài trợ, năm 2007, Công ty Pi C&E biên soạn phát hành "Sổ tay hướng dẫn "Rào cản xanh"...
Ngày tải lên: 06/02/2014, 20:27