... history of colon cancer); 2) An ECOG Performance Status Score of to or a Karnofsky's Performance score of 60 to 100%; 3) Age 18 years or older; 4) Patient able to comprehend the nature of the ... patients treated with beads with liver dominant hepatic metastasis after ingDisease Free Survival failing standardSurvival ofIrinotecan drug elutingIrinotecan drug eluting beads with liver dominant ... metastasis of AH 7974 cells in rats Chem Pharm Bull (Tokyo) 1981, 29:1433-1438 Tang Y, Taylor RR, Gonzalez MV, Lewis AL, Stratford PW: Evaluation of irinotecan drug- eluting beads: a new drug- device...
Ngày tải lên: 09/08/2014, 04:21
... consists of eight sessions Like in regular CT, each PCT session follows a fixed structure, with agenda setting, review of homework, explanation of rationale of each session, and assignment of homework ... of bipolar illness, any psychotic disorder (current and previous), alcohol or drug misuse, predominant anxiety disorder Assessment of Eligibility and Baseline Measures Informed consent We inform ... For a complete overview of the assessments see Table Participants in the M-CT group will also answer questions of the Dutch version of the Credibility and expectancy questionnaire [37,38] before...
Ngày tải lên: 11/08/2014, 16:23
báo cáo khoa học: "Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohor" pot
... allowing breaking up of the large haplotype block and thus allowing inference of the relative effects of each SNP The task of demonstrating the basis for causality, even of haplotypes, is not ... altering drug response through regulation of expression of IL28B Additional material Additional file 1: Tables S1 to S5 Table S1: number of reads aligned for each comparison Table S2: results of the ... Alignment/Map format and SAMtools Bioinformatics 2009, 25:2078-2079 Bansal V: A statistical method for the detection of variants from nextgeneration resequencing of DNA pools Bioinformatics 2010,...
Ngày tải lên: 11/08/2014, 12:21
Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... Serum levels of an isoform of apolipoprotein A-II as a potential marker for prostate cancer Clin.Cancer.Res.2005; 11:1073-1085 25 Zeidan BA, Townsend PA SELDI-TOF proteomic profiling of breast carcinomas ... [29] The initial serum proteome profiles of CRC were generated by using the combination of MALDI-TOF MS and WCX magnetic beads as well as pattern recognition software in our study The 68 different ... were eluted from the magnetic beads using 10 μl of 0.5% trifluoroacetic acid Then, μl of the eluted sample was diluted 1:2 fold in μl of SPA (saturated solution of sinapinic acid in 50% acetonitrile...
Ngày tải lên: 25/10/2012, 11:18
Tài liệu Development of an Observe-By-Wire System for Forklifts Using Haptic Interfaces pptx
... operator in term of the sense of touch 2.2 Feedback force implementation: According to previous research [9], [10], the steering system of forklifts is developed Moreover, driving torque of forklift ... improve the visibility as well as forklift performances OBSERVE BY WIRE FOR FORKLIFTS 2.1 System overview Operating a forklift is a specialized job Drivers control forks and its direction through ... configuration, a forklift lifts loads to the third floor for stacking or storage (a): forklift operation; (b): distance measurement using four distance sensors and feedback force implementation using a...
Ngày tải lên: 17/12/2013, 11:15
Tài liệu Development of an Observe-By-Wire System for Forklifts Using Haptic Interfaces docx
... operator in term of the sense of touch 2.2 Feedback force implementation: According to previous research [9], [10], the steering system of forklifts is developed Moreover, driving torque of forklift ... improve the visibility as well as forklift performances OBSERVE BY WIRE FOR FORKLIFTS 2.1 System overview Operating a forklift is a specialized job Drivers control forks and its direction through ... configuration, a forklift lifts loads to the third floor for stacking or storage (a): forklift operation; (b): distance measurement using four distance sensors and feedback force implementation using a...
Ngày tải lên: 23/12/2013, 00:15
A study of using english songs as a type of supplementary material in teaching listening for first year non major students of english at phuong dong university
... enormous information about the author of the song, the root of it and even the words of the song So there are no reasons for not making advantage of such a useful and potential source of teaching ... word is It, therefore, can be seen that the two processes are both important for learners in understanding the language since both of them can offer keys to determining the meaning of spoken discourse ... is the process of understanding speech in a second or foreign language The study of listening comprehension processes in second or foreign language learning focuses on the role of individual linguistic...
Ngày tải lên: 29/01/2014, 10:33
Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt
... previously demonstrated the application of this method to the determination of the glycan structure of a form of AFP [10] However, identification of the details of a glycan structural change on a glycoprotein ... microarray system is the best tool for a ‘cell profiler’, and it is expected to be applicable for selection of cancer-specific lectins and for quality control of stem cells before transplantation [12–15] ... dissociation spectra Therefore, structural assignment of the complicated glycans can be performed by using MSn spectral libraries without the need for detailed identification of fragment ions Indeed,...
Ngày tải lên: 16/02/2014, 08:20
Tài liệu Báo cáo khoa học: "Keyword Extraction using Term-Domain Interdependence for Dictation of Radio News" ppt
... calculated feature vectors for classifying domains of each unit of radio news and for extracting keywords Our previous system could not extract some keywords because of many noisy keywords In ... 1997), and frequency of each noun are counted Next, similarity between FeaVe of each domain and each newspaper article are calculated by using formula (1) Finally, a suitable domain of each newspaper ... number of phonemes of wordk Xk,j is x2value of wordk for domainj The system selects a word path whose Siml(i,j) is the largest among all word paths for domainj Figure shows the method of calculating...
Ngày tải lên: 20/02/2014, 18:20
The Future of Organization’s Computer Network Security for the Next 5 Years (2011-2015) by Using Delphi Technique doc
... information, so protecting the data or information is very important and necessary in the information age In this era, who possesses more information has the advantage Therefore, if the information ... Graduate Research Journal of Information Technology Education, Volume 6, 2007 [4] M Tiantong Delphi Technique F aculty of Information Technology, King Mongkut's University of Technology North Bangkok, ... ranking of the important issues for management decision research However, studies over the past few years have not used the Delphi technique which requires rigid rules for the process of selecting...
Ngày tải lên: 05/03/2014, 23:20
Báo cáo khoa học: Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138 pot
... availability of a range of structures of NNRTIresistant RTs drugs will provide greater understanding of the molecular basis of drug resistance mechanisms Such data will contribute to the design of novel ... coloured red for wild-type RT and cyan for mutant RTs For clarity, the side-chains at the site of mutation are shown in magenta for wild-type and green for the mutants Hydrogen bonds linking drug to ... the side-chain of Lys101 [24] Consistent with the reports of the selection of Lys101Glu in clinical use of efavirenz, the crystal structure of RT with this NNRTI shows a contact of the inhibitor...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: Using directed evolution to improve the solubility of the C-terminal domain of Escherichia coli aminopeptidase P Implications for metal binding and protein stability pptx
... this stage, mutants of a single-length fragment were selected for a further round of shuffling Two further rounds of shuffling were completed before a mutated fragment was selected for expression, ... digestion of the AMPP gene (pepP) The gene fragments gave rise to a series of protein fragments that were examined for their solubility by fusing them to DHFR and monitoring the absence or presence of ... in a loss of functional activity The object of this study was to increase the solubility of the C-terminal domain of AMPP, and in so doing to determine which residues are responsible for its poor...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: "Using Chunk Based Partial Parsing of Spontaneous Speech in Unrestricted Domains for Reducing Word Error Rate in Speech Recognition" potx
... hypothesis length cutoffs (for the cutoff filter); number of hidden units; number of training epochs The net with the best performance on the test set has one hidden unit, and is trained for 10 epochs ... potential benefit of selecting good candidates for reranking in the firstplace Comparison: Human Study One of our motivations for using syntactic representations for the task of Nbest listreranking ... improvement of the P O S tagger: Since the performance of this component was shown to be of essential importance for later stages of the system, we expect to see benefits from putting efforts into...
Ngày tải lên: 23/03/2014, 19:20
Designing a supply chain Proposition for improving quality and overall productivity of enterprises using business model
... company's logic of earning money It is a description of the value a company offers to one or several segments of 11 customers and the architecture of the firm and its network of partners for creating, ... partial fulfillment of the requirements for the degree of Master of Science in Industrial and Systems Engineering in the Graduate School of Binghamton University State University of New York 2010 ... failure One of the prime reasons behind industries failure, loss of market or loss of revenue is the misbalance created between right products and right quantity of products Most of the time...
Ngày tải lên: 01/06/2014, 13:59
Báo cáo hóa học: " Drug-eluting Ti wires with titania nanotube arrays for bone fixation and reduced bone infection" potx
... capability of TNTs for local delivery of different therapeutics including water insoluble drugs, antibiotics and sensitive drugs such as proteins from the implant surface at the site of implantation ... the drug- loaded TNTs were characterised, and the peak of the drug was identified in order to calculate the correct amount of drug present Drug release characterisation Drug release from the drug- loaded ... substantial amount of drug into the nanotubes Quantitative analysis of drug loading To determine the amount of drug loaded in the nanotubes, thermo-gravimetric analysis [TGA] was performed In order...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo hóa học: " A rapid, convenient, solventless green approach for the synthesis of oximes using grindstone chemistry" docx
... mortar with a pestle for the required period of time On completion of the reaction as Table Reusability of Bi2O3 in the preparation of 2b using 60 mol% of the catalyst Entry Run number Time Yield ... 60-98% yield 90 Page of run might be due to the loss of active sites of the catalyst Conclusions To the best of our knowledge, Bi O has never been used in the synthesis of oximes earlier In conclusion, ... Typical procedure for the formation of oxime A mixture of aldehyde/ketone (1 mmol), hydroxylamine hydrochloride (1.2 mmol), and Bi 2O3 (0.6 mmol) was grounded in a mortar with a pestle for the required...
Ngày tải lên: 20/06/2014, 22:20
báo cáo hóa học: " Beyond platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery vector" ppt
... http://www.nanoscalereslett.com/content/6/1/445 capable of inducing oxidative stress, which is of great concern in terms of the nanotoxicology of particles being pursued for a variety of consumer products Furthermore, ... of 10 B C Figure Characterization of CuCNPs (A) SEM image of CuCNPs, (B) EDX spectra of CNPs before (left) and after (right) addition of Cu, (C) XPS spectra for CuCNPs (right) and control particles ... molecule in general from a delivery are major factors that ultimately determine the success or failure of that vector when applied to targeted drug delivery One of the goals of this work was to demonstrate...
Ngày tải lên: 21/06/2014, 02:20
Báo cáo hóa học: " Investigation of utilization of nanosuspension formulation to enhance exposure of 1,3dicyclohexylurea in rats: Preparation for PK/PD study via subcutaneous route of nanosuspension drug delivery" doc
... Investigation of utilization of nanosuspension formulation to enhance exposure of 1,3dicyclohexylurea in rats: Preparation for PK/PD study via subcutaneous route of nanosuspension drug delivery Nanoscale ... it cannot be formulated for IV delivery without a high percentage of organic cosolvents which is incompatible with animal models in terms of efficacy An alternative IV formulation using nanosuspension ... of the drug In order to overcome these limitations, a suitable formulation was needed to maximize the potential of DCU in vivo Several formulations strategies for SC dose have been assessed Formulations...
Ngày tải lên: 21/06/2014, 03:20
Báo cáo hóa học: "Research Article Comparative Study of Local SAD and Dynamic Programming for Stereo Processing Using Dedicated Hardware" ppt
... expand as a search for optimal path in a 3D search space, formed as a stack of cost planes from adjacent scanlines The cost of a set of paths is now defined as the sum of the costs of individual paths ... quality of the final disparity maps For the assessment of the systems a hardware/software platform is developed, which is suitable to prototype and test image processing functions The assessment of ... order to form appropriate windows is achieved using delay lines For example, a shift of a whole scanline between pixels in a rectangular window needs a 640-pixel-deep shift register, for an image...
Ngày tải lên: 21/06/2014, 19:20
Báo cáo hóa học: " Combination of Polymer Technology and Carbon Nanotube Array for the Development of an Effective Drug Delivery System at Cellular Leve" pptx
... exposition before cell culture experiments The CNT array owns a forest-like structure that could be exploited for the deposition of a polymeric thin film acting as drug delivery device For drug release ... can form extended neural network upon differentiation [5] In this study, we propose a combination of drug delivery system with such CNT array, exploiting a thin film of calcium alginate as drug ... to form microbundles, driven by the capillary force of water droplets In order to prevent the CNT sticking in a liquid environment, and to improve mechanical features of CNTs, a thin layer of...
Ngày tải lên: 22/06/2014, 00:20