... Diseases of the Prostate Benign and Malignant Diseases of the Prostate: Introduction Benign and malignant changes in the prostate increase with age. Autopsies of men in the eighth decade of life ... although the disease remains the second leading Chapter 091. Benign and Malignant Diseases of the Prostate (Part 1) Harrison's Internal Medicine > Chapter 91. Benign and Malignant Diseases ... in >90% and malignant changes in >70% of individuals. The high prevalence of these diseases among the elderly, who often have competing causes of morbidity and mortality, mandates a risk-adapted...
Ngày tải lên: 07/07/2014, 02:20
... proviso that the risks and benefits of the performance of these Chapter 091. Benign and Malignant Diseases of the Prostate (Part 2) Diagnosis and Treatment by Clinical State The disease continuum—from ... were high-grade [37% (280 of 757 cancers) vs. 22% (237 of 1068 cancers) for the placebo group] have been shown to be an artifact of the reduced volume of the malignant epithelial cells in finasteride-treated ... assessment, the decision to offer treatment and the specific form of treatment is based on the risk posed by the cancer, relative to Prevention Several agents are under investigation for their...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 3) docx
... biopsy. Each core of the biopsy is examined for the presence of cancer, and the amount of cancer is quantified based on the length of the tumor within the core and the percentage of the core involved. ... evolved over time. The goal is to increase the sensitivity of the test for younger men more likely to die of the disease and to reduce the frequency of detecting cancers of low malignant potential ... localized, 40% are not palpable, and of these, 70% are pathologically organ-confined. The Chapter 091. Benign and Malignant Diseases of the Prostate (Part 3) The PSA criteria used to recommend...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 4) potx
... confined to the gland (T2), and those that have extended outside the gland (T3 and T4) (Table 91-1). DRE alone is inaccurate with respect to the extent of the disease within the gland, the presence ... absence of capsular invasion, involvement of seminal vesicles, and extension of disease to lymph nodes. Because of the inadequacy of DRE for staging, the staging system was modified to include the ... Chapter 091. Benign and Malignant Diseases of the Prostate (Part 4) Pathology The noninvasive proliferation of epithelial cells within ducts is termed prostatic intraepithelial neoplasia....
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 5) pot
... evidence for the superiority of any one treatment. Comparison of outcomes of various forms of therapy is limited by the lack of prospective trials, referral bias, and differences in the outcomes ... localized disease are managed by radical surgery, radiation therapy, or active surveillance. Choice of therapy requires the consideration of several factors: the presence of symptoms, the probability ... Chapter 091. Benign and Malignant Diseases of the Prostate (Part 5) TRUS is the imaging technique most frequently used to assess the primary tumor, but its chief use...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 6) docx
... disruption of the vascular supply and not the nerve fibers. Neoadjuvant hormone therapy has also been studied in combination with radiation therapy. The aim is to decrease the size of the prostate and, ... intensity-modulated radiation therapy Chapter 091. Benign and Malignant Diseases of the Prostate (Part 6) Radical Prostatectomy The goal of radical prostatectomy is to excise the cancer completely ... patients who received >70 Gy. The frequency of erectile dysfunction is related to the quality of erections pretreatment, the dose administered, and the time of assessment. Postradiation erectile...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 7) potx
... evidence of disease on scan. For these patients the central issue is whether the rise in PSA results from persistent disease in the primary site, systemic disease, or both. In theory, disease in the ... disease had spread outside of the area of the prostate bed and is unlikely to be controlled with radiation therapy. disease. The practice evolved from studies of predominantly ... radiation therapy. The decision to recommend radiation therapy after prostatectomy is often made on the basis of the pathologic findings at surgery, as imaging studies such as CT and bone scan...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 8) docx
... Chapter 091. Benign and Malignant Diseases of the Prostate (Part 8) For patients with a rising PSA after radiation therapy, salvage prostatectomy can be considered if the disease was "curable" ... hormone and follicle-stimulating hormone followed by a downregulation of receptors in the pituitary gland, which effects a chemical castration. They were approved on the basis of randomized ... disease was "curable" at the outset, if persistent disease has been documented by a biopsy of the prostate, and if no metastatic disease is seen on imaging studies. Unfortunately, case...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 9) pdf
... 091. Benign and Malignant Diseases of the Prostate (Part 9) Antiandrogens Nonsteroidal antiandrogens such as flutamide, bicalutamide, and nilutamide block the binding of androgens to the ... metastatic disease. Nevertheless, some men may accept the trade-off of a potentially inferior cancer outcome for an improved quality of life. Combined androgen blockade the administration of an antiandrogen ... analogue receive an antiandrogen for the first 2–4 weeks of treatment to protect against the flare. Intermittent Hormone Therapy Another way to reduce the side effects of androgen depletion is...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 11) pdf
Ngày tải lên: 07/07/2014, 02:20
báo cáo khoa học: "Synchronous double primary malignant tumor of the gallbladder and liver: a case report" potx
Ngày tải lên: 09/08/2014, 02:20
Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck potx
Ngày tải lên: 10/08/2014, 05:21
Báo cáo khoa học: "Indications and recommended approach for surgical intervention of metastatic disease to the gallbladder" ppt
Ngày tải lên: 09/08/2014, 03:22
Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf
... significantly increases the cost of the purification, and the require- ment for HPLC increases the length and complexity of the purification procedure. Moreover, as with the studies by Lee et al. [21] and Subramanian ... Subramanian and Shree [42], there was no rigorous assessment of the purity of the product or the correctness of the sequence. In con- trast, the purification protocol that we have developed is quick and ... line) and 9 lM (triangles, dashed line). Each data point is the mean of eight replicates ± the standard error; where error bars are not visible, the standard error was smaller than the size of the...
Ngày tải lên: 18/02/2014, 13:20
báo cáo hóa học:" Revision hip replacement for recurrent Hydatid disease of the pelvis: a case report and review of the literature" doc
... organs. Due to their physiologic role as capillary filters and their vast capillary volume, the liver and lung are most often affected. The brain, the muscle s or the bones are the more frequently ... all aroundthehip(Figure5).Shewasgiventheoptionof Figure 1 Radiograph showing involvement of Right ilium and hip by the Hydatid disease. Figure 2 CT scan showing destruction of the hip with superior migration of the femoral head into the ... involves liver and lung. There are many reports on Hydatid disease w ith the involve- ment of the musculoskeletal system [1-11]. Involvement of the musculoskeletal system occurs in 1% to 4% of all cases...
Ngày tải lên: 20/06/2014, 04:20
ANEURYSMAL DISEASE OF THE THORACIC AND ABDOMINAL AORTA pptx
... able to locate the aneurysm neck and iliac arteries, thus adding to the visual evaluation of the anatomy and quality of the tissues. The internal hand also compensates for lack of the tri-dimensional ... lies in the semi-decubitus position on the right. The operating surgeon (*) stands on the right of the patient. After retrocolic dissection the operating surgeon (*) stands on the left of the patient ... complete treatment of aneurysmal disease with obliteration of the aneurysmal sac and debridement of its clot and atheromatous debris and most importantly is of proven durability. Of all the technical...
Ngày tải lên: 27/06/2014, 17:20